1,168 results on '"Tamai, Ikumi"'
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2. Uric acid in health and disease: From physiological functions to pathogenic mechanisms
3. Quantitative analysis of gastrointestinal fluid absorption and secretion to estimate luminal fluid dynamics in rats
4. Induction of open-form bile canaliculus formation by hepatocytes for evaluation of biliary drug excretion
5. Drug–drug conjugates of MEK and Akt inhibitors for RAS-mutant cancers
6. Contributions of multiple transport mechanisms to intestinal uptake of serotonin
7. Three-dimensional Culture of Human Proximal Tubular Epithelial Cells for an in vitro Evaluation of Drug-induced Kidney Injury
8. Association between switching prescribed drugs for lower urinary tract symptoms and independence of urination in post-stroke patients: A retrospective cohort study
9. Apple-derived extracellular vesicles modulate the expression of human intestinal bile acid transporter ASBT/SLC10A2 via downregulation of transcription factor RARα
10. Quantitative Analysis of Gastrointestinal Water Dynamics by Means of a Physiologically Based Fluid Kinetic Model
11. Characterization of Aripiprazole Uptake Transporter in the Blood-Brain Barrier Model hCMEC/D3 Cells by Targeted siRNA Screening
12. Unique Binding Sites of Uricosuric Agent Dotinurad for Selective Inhibition of Renal Uric Acid Reabsorptive Transporter URAT1
13. Evaluation of biliary excretion process of drugs and bile acids using permeation assay by a novel in vitro hepatocyte culture system (ICHEP)
14. Roles and Application of Extracellular Vesicles Occurring Endogenously and Naturally
15. Multiple Transport Mechanisms Involved in the Intestinal Absorption of Metformin: Impact on the Nonlinear Absorption Kinetics
16. Drug–drug conjugates of MEK and Akt inhibitors for RAS-mutant cancers
17. Model Analysis of the Apparent Saturation Kinetics of Purine Nucleobase Uptake in Cells co-Expressing Transporter and Metabolic Enzyme
18. Assessment of drug transporters involved in the urinary secretion of [99mTc]dimercaptosuccinic acid
19. A Novel Fluorescence-Based Method to Evaluate Ileal Apical Sodium-Dependent Bile Acid Transporter ASBT
20. [131I]MIBG exports via MRP transporters and inhibition of the MRP transporters improves accumulation of [131I]MIBG in neuroblastoma
21. Uptake Pathway of Apple-derived Nanoparticle by Intestinal Cells to Deliver its Cargo
22. Contribution of Prostaglandin Transporter OATP2A1/SLCO2A1 to Placenta-to-Maternal Hormone Signaling and Labor Induction
23. Transport mechanism and affinity of [99mTc]Tc-mercaptoacetyltriglycine ([99mTc]MAG3) on the apical membrane of renal proximal tubule cells
24. Quantitative analysis of the impact of membrane permeability on intestinal first‐pass metabolism of CYP3A substrates
25. Influence of osmolality on gastrointestinal fluid volume and drug absorption: potential impact on oral salt supplementation
26. Role of Organic Anion Transporter NPT4 in Renal Handling of Uremic Toxin 3-indoxyl Sulfate
27. Rat Kidney Slices for Evaluation of Apical Membrane Transporters in Proximal Tubular Cells
28. Quantitative analysis of the impact of membrane permeability on intestinal first‐pass metabolism of CYP3A substrates.
29. Potentiation of the Uricosuric Effect of Dotinurad byTrans-Inhibition of the Uric Acid Reabsorptive Transporter URAT1
30. Pillar[6]arene acts as a biosensor for quantitative detection of a vitamin metabolite in crude biological samples
31. Improvement of Protein Expression Profile in Three-Dimensional Renal Proximal Tubular Epithelial Cell Spheroids Selected Based on OAT1 Gene Expression: A Potential In Vitro Tool for Evaluating Human Renal Proximal Tubular Toxicity and Drug Disposition
32. A NovelIn VitroHepatocyte Culture System (icHep) for Biliary Drug Excretion Analysis Using Permeation Assay
33. Different Involvement of OAT in Renal Disposition of Oral Anticoagulants Rivaroxaban, Dabigatran, and Apixaban
34. Impact of FDA-Approved Drugs on the Prostaglandin Transporter OATP2A1/SLCO2A1
35. Association of miR-145 With Statin-Induced Skeletal Muscle Toxicity in Human Rhabdomyosarcoma RD Cells
36. Inhibitory Effect of Crizotinib on Creatinine Uptake by Renal Secretory Transporter OCT2
37. Author Correction: Imaging of hepatic drug transporters with [131I]6-β-iodomethyl-19-norcholesterol
38. Biological Distribution after Oral Administration of Radioiodine-Labeled Acetaminophen to Estimate Gastrointestinal Absorption Function via OATPs, OATs, and/or MRPs
39. A single high-dose irradiation changes accumulation of methotrexate and gene expression levels of SLC and ABC transporters in cancer cells
40. Apple juice relieves loperamide-induced constipation in rats by downregulating the intestinal apical sodium-dependent bile acid transporter ASBT
41. Carrier-Mediated Prodrug Uptake to Improve the Oral Bioavailability of Polar Drugs: An Application to an Oseltamivir Analogue
42. The change of pharmacokinetics of fexofenadine enantiomers through the single and simultaneous grapefruit juice ingestion
43. Imaging of hepatic drug transporters with [131I]6-β-iodomethyl-19-norcholesterol
44. Identification of the Catechin Uptake Transporter Responsible for Intestinal Absorption of Epigallocatechin Gallate in Mice
45. Identification of MRP2 as a targetable factor limiting oxaliplatin accumulation and response in gastrointestinal cancer
46. Different Efflux Transporter Affinity and Metabolism of 99mTc-2-Methoxyisobutylisonitrile and 99mTc-Tetrofosmin for Multidrug Resistance Monitoring in Cancer
47. Saturable Hepatic Extraction of Gemcitabine Involves Biphasic Uptake Mediated by Nucleoside Transporters Equilibrative Nucleoside Transporter 1 and 2
48. Involvement of Concentrative Nucleoside Transporter 1 in Intestinal Absorption of Trifluridine Using Human Small Intestinal Epithelial Cells
49. Kinetic Evaluation of Determinant Factors for Cellular Accumulation of Protoporphyrin IX Induced by External 5-Aminolevulinic Acid for Photodynamic Cancer Therapy
50. Dehydroepiandrosterone sulfate, a useful endogenous probe for evaluation of drug–drug interaction on hepatic organic anion transporting polypeptide (OATP) in cynomolgus monkeys
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