Search

Your search keyword '"Takx, Richard A. P."' showing total 322 results
Start Over Author "Takx, Richard A. P."
322 results on '"Takx, Richard A. P."'

2. Automatic Coronary Artery Plaque Quantification and CAD-RADS Prediction using Mesh Priors

Author

van Herten, Rudolf L. M., Hampe, Nils, Takx, Richard A. P., Franssen, Klaas Jan, Wang, Yining, Suchá, Dominika, Henriques, José P., Leiner, Tim, Planken, R. Nils, and Išgum, Ivana

Subjects
Electrical Engineering and Systems Science - Image and Video Processing
Abstract

Coronary artery disease (CAD) remains the leading cause of death worldwide. Patients with suspected CAD undergo coronary CT angiography (CCTA) to evaluate the risk of cardiovascular events and determine the treatment. Clinical analysis of coronary arteries in CCTA comprises the identification of atherosclerotic plaque, as well as the grading of any coronary artery stenosis typically obtained through the CAD-Reporting and Data System (CAD-RADS). This requires analysis of the coronary lumen and plaque. While voxel-wise segmentation is a commonly used approach in various segmentation tasks, it does not guarantee topologically plausible shapes. To address this, in this work, we propose to directly infer surface meshes for coronary artery lumen and plaque based on a centerline prior and use it in the downstream task of CAD-RADS scoring. The method is developed and evaluated using a total of 2407 CCTA scans. Our method achieved lesion-wise volume intraclass correlation coefficients of 0.98, 0.79, and 0.85 for calcified, non-calcified, and total plaque volume respectively. Patient-level CAD-RADS categorization was evaluated on a representative hold-out test set of 300 scans, for which the achieved linearly weighted kappa ($\kappa$) was 0.75. CAD-RADS categorization on the set of 658 scans from another hospital and scanner led to a $\kappa$ of 0.71. The results demonstrate that direct inference of coronary artery meshes for lumen and plaque is feasible, and allows for the automated prediction of routinely performed CAD-RADS categorization., Comment: 12 pages, 6 figures, accepted in IEEE Transactions on Medical Imaging

Published
2023

3. Deep Learning from Dual-Energy Information for Whole-Heart Segmentation in Dual-Energy and Single-Energy Non-Contrast-Enhanced Cardiac CT

Author

Bruns, Steffen, Wolterink, Jelmer M., Takx, Richard A. P., van Hamersvelt, Robbert W., Suchá, Dominika, Viergever, Max A., Leiner, Tim, and Išgum, Ivana

Subjects
Electrical Engineering and Systems Science - Image and Video Processing, Computer Science - Machine Learning
Abstract

Deep learning-based whole-heart segmentation in coronary CT angiography (CCTA) allows the extraction of quantitative imaging measures for cardiovascular risk prediction. Automatic extraction of these measures in patients undergoing only non-contrast-enhanced CT (NCCT) scanning would be valuable. In this work, we leverage information provided by a dual-layer detector CT scanner to obtain a reference standard in virtual non-contrast (VNC) CT images mimicking NCCT images, and train a 3D convolutional neural network (CNN) for the segmentation of VNC as well as NCCT images. Contrast-enhanced acquisitions on a dual-layer detector CT scanner were reconstructed into a CCTA and a perfectly aligned VNC image. In each CCTA image, manual reference segmentations of the left ventricular (LV) myocardium, LV cavity, right ventricle, left atrium, right atrium, ascending aorta, and pulmonary artery trunk were obtained and propagated to the corresponding VNC image. These VNC images and reference segmentations were used to train 3D CNNs for automatic segmentation in either VNC images or NCCT images. Automatic segmentations in VNC images showed good agreement with reference segmentations, with an average Dice similarity coefficient of 0.897 \pm 0.034 and an average symmetric surface distance of 1.42 \pm 0.45 mm. Volume differences [95% confidence interval] between automatic NCCT and reference CCTA segmentations were -19 [-67; 30] mL for LV myocardium, -25 [-78; 29] mL for LV cavity, -29 [-73; 14] mL for right ventricle, -20 [-62; 21] mL for left atrium, and -19 [-73; 34] mL for right atrium, respectively. In 214 (74%) NCCT images from an independent multi-vendor multi-center set, two observers agreed that the automatic segmentation was mostly accurate or better. This method might enable quantification of additional cardiac measures from NCCT images for improved cardiovascular risk prediction.

Published
2020
Full Text
View/download PDF

4. Deep Learning-Based Regression and Classification for Automatic Landmark Localization in Medical Images

Author

Noothout, Julia M. H., de Vos, Bob D., Wolterink, Jelmer M., Postma, Elbrich M., Smeets, Paul A. M., Takx, Richard A. P., Leiner, Tim, Viergever, Max A., and Išgum, Ivana

Subjects
Electrical Engineering and Systems Science - Image and Video Processing, Computer Science - Computer Vision and Pattern Recognition, Physics - Medical Physics
Abstract

In this study, we propose a fast and accurate method to automatically localize anatomical landmarks in medical images. We employ a global-to-local localization approach using fully convolutional neural networks (FCNNs). First, a global FCNN localizes multiple landmarks through the analysis of image patches, performing regression and classification simultaneously. In regression, displacement vectors pointing from the center of image patches towards landmark locations are determined. In classification, presence of landmarks of interest in the patch is established. Global landmark locations are obtained by averaging the predicted displacement vectors, where the contribution of each displacement vector is weighted by the posterior classification probability of the patch that it is pointing from. Subsequently, for each landmark localized with global localization, local analysis is performed. Specialized FCNNs refine the global landmark locations by analyzing local sub-images in a similar manner, i.e. by performing regression and classification simultaneously and combining the results. Evaluation was performed through localization of 8 anatomical landmarks in CCTA scans, 2 landmarks in olfactory MR scans, and 19 landmarks in cephalometric X-rays. We demonstrate that the method performs similarly to a second observer and is able to localize landmarks in a diverse set of medical images, differing in image modality, image dimensionality, and anatomical coverage., Comment: 12 pages, accepted at IEEE transactions in Medical Imaging

Published
2020
Full Text
View/download PDF

5. Inflammation of the periodontium associates with risk of future cardiovascular events

Author

Van Dyke, Thomas E, Kholy, Karim El, Ishai, Amorina, Takx, Richard AP, Mezue, Kene, Abohashem, Shady M, Ali, Abdelrahman, Yuan, Neal, Hsue, Priscilla, Osborne, Michael T, and Tawakol, Ahmed

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Heart Disease, Cardiovascular, Clinical Research, Prevention, Aging, Biomedical Imaging, Good Health and Well Being, Cardiovascular Diseases, Female, Humans, Inflammation, Male, Middle Aged, Periodontium, Positron Emission Tomography Computed Tomography, Radiopharmaceuticals, Risk Factors, atherosclerosis, cardiovascular disease, &#160, periodontal disease, positron emission tomography,  periodontal disease, Dentistry
Abstract

BackgroundWhile growing evidence suggests a link between periodontal disease (PD) and cardiovascular disease (CVD), the independence of this association and the pathway remain unclear. Herein, we tested the hypotheses that: (1) inflammation of the periodontium (PDinflammation ) predicts future CVD independently of disease risk factors shared between CVD and PD, and (2) the mechanism linking the two diseases involves heightened arterial inflammation.Methods18 F-fluorodeoxyglucose positron emission tomography/computed tomography (18 F-FDG-PET/CT) imaging was performed in 304 individuals (median age 54 years; 42.4% male) largely for cancer screening; individuals without active cancer were included. PDinflammation and arterial inflammation were quantified using validated 18 F-FDG-PET/CT methods. Additionally, we evaluated the relationship between PDinflammation and subsequent major adverse cardiovascular events (MACE) using Cox models and log-rank tests.ResultsThirteen individuals developed MACE during follow-up (median 4.1 years). PDinflammation associated with arterial inflammation, remaining significant after adjusting for PD and CVD risk factors (standardized β [95% CI]: 0.30 [0.20-0.40], P

Published
2021

7. Association of Arterial and Lymph Node Inflammation With Distinct Inflammatory Pathways in Human Immunodeficiency Virus Infection

Author

Tawakol, Ahmed, Ishai, Amorina, Li, Danny, Takx, Richard AP, Hur, Sophia, Kaiser, Yannick, Pampaloni, Miguel, Rupert, Adam, Hsu, Denise, Sereti, Irini, Fromentin, Rémi, Chomont, Nicolas, Ganz, Peter, Deeks, Steven G, and Hsue, Priscilla Y

Subjects
Medical Microbiology, Biomedical and Clinical Sciences, Immunology, Infectious Diseases, HIV/AIDS, Clinical Research, Sexually Transmitted Infections, 2.1 Biological and endogenous factors, Infection, Inflammatory and immune system, Good Health and Well Being, Arteritis, CD4 Lymphocyte Count, California, Case-Control Studies, DNA, Viral, HIV, HIV Infections, Humans, Incidence, Lymph Nodes, Lymphadenitis, Male, Middle Aged, Positron-Emission Tomography, Viral Load, Cardiovascular medicine and haematology
Abstract

ImportanceHuman immunodeficiency virus (HIV) infection is associated with a high risk of cardiovascular disease and increased arterial inflammation. In HIV, inflammation is also increased within lymph nodes (LNs), tissues known to harbor the virus even among treated and suppressed individuals.ObjectiveTo test the hypothesis that arterial inflammation is linked to HIV disease activity and to inflammation within HIV-infected tissues (LNs).Design, setting, and participantsFor this case-control study, participants were recruited from the SCOPE (Observational Study of the Consequences of the Protease Inhibitor Era) cohort, a clinic-based cohort of individuals receiving care at San Francisco General Hospital and the San Francisco Veteran's Affairs Medical Center. Arterial and LN inflammation were measured using 18F-fluorodeoxyglucose positron emission tomography. Detailed immunophenotyping was performed, along with measurement of viral activity/persistence and of circulating inflammatory biomarkers.Main outcomes and measuresArterial and LN inflammation.ResultsA total of 74 men were studied (45 HIV-infected men with a median age of 53 years [interquartile range, 49-59 years] and 29 uninfected male controls with a median age of 52 years [interquartile range, 46-56 years]). Lymph node inflammation was higher in HIV-infected individuals and correlated with markers of viral disease activity (viral load, CD8+ T cells, and CD4/CD8 ratio) and CD4+ T-cell activation. Uninfected controls had the lowest LN activity (mean [SD] maximum axillary LN standardized uptake value, 1.53 [0.56]), the elite controller and ART-suppressed groups had intermediate levels of LN (mean [SD] maximum axillary LN standardized uptake value, 2.12 [0.87] and 2.32 [1.79], respectively), and the noncontrollers had the highest activity (mean [SD] maximum axillary LN standardized uptake value, 8.82 [3.08]). Arterial inflammation was modestly increased in HIV-infected individuals and was positively correlated with circulating inflammatory biomarkers (high-sensitivity C-reactive protein and IL-6) and activated monocytes (CD14dimCD16+; nonclassical) but not with markers of HIV. While LN and arterial inflammation were increased in HIV, inflammatory activity in these tissues was not related (r = 0.09, P = .56).Conclusions and relevanceWhile LNs and, to a lesser degree, the arterial wall are inflamed in HIV, inflammation in these tissues is not closely linked. Namely, measures of HIV disease activity are strongly associated with LN inflammation but not with arterial inflammation. These data suggest that LN and arterial inflammation do not share underlying pathways of immune activation and also that therapeutic interventions that reduce viral disease activity may not predictably reduce arterial inflammation in HIV or its downstream consequence (ie, cardiovascular disease).

Published
2017

9. Imaging of intracranial arterial disease: a comparison between MRI and unenhanced CT

Author

Arts-assistenten Radiologie, Cardiovasculaire Epi Team 7a, Computational Imaging, Onderzoek Beeld, MS Radiologie, Brain, Cancer, Circulatory Health, Researchgr. Systems Radiology, Infection & Immunity, Regenerative Medicine and Stem Cells, Divisie Beeld & Oncologie, Lucci, Carlo, Rissanen, Ina, Takx, Richard A P, van der Kolk, Anja G, Harteveld, Anita A, Dankbaar, Jan W, Geerlings, Mirjam I, de Jong, Pim A, Hendrikse, Jeroen, Arts-assistenten Radiologie, Cardiovasculaire Epi Team 7a, Computational Imaging, Onderzoek Beeld, MS Radiologie, Brain, Cancer, Circulatory Health, Researchgr. Systems Radiology, Infection & Immunity, Regenerative Medicine and Stem Cells, Divisie Beeld & Oncologie, Lucci, Carlo, Rissanen, Ina, Takx, Richard A P, van der Kolk, Anja G, Harteveld, Anita A, Dankbaar, Jan W, Geerlings, Mirjam I, de Jong, Pim A, and Hendrikse, Jeroen

Published
2024

10. Automatic Coronary Artery Plaque Quantification and CAD-RADS Prediction using Mesh Priors

Author

MS Radiologie, Circulatory Health, Van Herten, Rudolf L M, Hampe, Nils, Takx, Richard A P, Franssen, Klaas Jan, Wang, Yining, Sucha, Dominika, Henriques, Jose P, Leiner, Tim, Planken, R Nils, Isgum, Ivana, MS Radiologie, Circulatory Health, Van Herten, Rudolf L M, Hampe, Nils, Takx, Richard A P, Franssen, Klaas Jan, Wang, Yining, Sucha, Dominika, Henriques, Jose P, Leiner, Tim, Planken, R Nils, and Isgum, Ivana

Published
2024

16. Detection of Cardioembolic Sources With Nongated Cardiac Computed Tomography Angiography in Acute Stroke: Results From the ENCLOSE Study

Author

Opleiding Neurologie, Researchgr. Hart-brein as., Brain, Circulatory Health, Onderzoek Beeld, Team Medisch, Fysica Radiologie, Beeldverwerking ISI, Cancer, Neurologen, MS Radiologie, Kauw, Frans, Velthuis, Birgitta K, Takx, Richard A P, Guglielmo, Marco, Cramer, Maarten J, van Ommen, Fasco, Bos, Anneloes, Bennink, Edwin, Marquering, Henk A., Kappelle, L Jaap, de Jong, Hugo W A M, Dankbaar, Jan W, Opleiding Neurologie, Researchgr. Hart-brein as., Brain, Circulatory Health, Onderzoek Beeld, Team Medisch, Fysica Radiologie, Beeldverwerking ISI, Cancer, Neurologen, MS Radiologie, Kauw, Frans, Velthuis, Birgitta K, Takx, Richard A P, Guglielmo, Marco, Cramer, Maarten J, van Ommen, Fasco, Bos, Anneloes, Bennink, Edwin, Marquering, Henk A., Kappelle, L Jaap, de Jong, Hugo W A M, and Dankbaar, Jan W

Published
2023

18. Clinical implementation of an emergency department coronary computed tomographic angiography protocol for triage of patients with suspected acute coronary syndrome

Author

Ghoshhajra, Brian B., Takx, Richard A. P., Staziaki, Pedro V., Vadvala, Harshna, Kim, Phillip, Neilan, Tomas G., Meyersohn, Nandini M., Bittner, Daniel, Janjua, Sumbal A., Mayrhofer, Thomas, Greenwald, Jeffrey L., Truong, Quyhn A., Abbara, Suhny, Brown, David F. M., Januzzi, James L., Francis, Sanjeev, Nagurney, John T., Hoffmann, Udo, Chan, Andy, Choy, Garry, Gupta, Rajiv, Kalra, Mannudeep, Karaosmanoglu, Ali, Levesque, Marie-Helene, Lu, Michael T., Oliveira, George R., Prabhakar, Anand M., Kulkarni, Naveen, Peterson, Paul Gabriel, Scheske, Jonathan, Singh, Parmanand, Pursnani, Amit, Panagia, Marcello, Sayegh, Karl, Sharma, Umesh, Walker, Christopher, Verzosa, Stacey, and on behalf of MGH Emergency Cardiac CTA Program Contributors

Published
2017
Full Text
View/download PDF

22. Automatic Coronary Artery Plaque Quantification and CAD-RADS Prediction Using Mesh Priors

Author

Herten, van Rudolf L. M., Hampe, Nils, Takx, Richard A. P., Franssen, Klaas Jan, Wang, Yining, Sucha, Dominika, Henriques, Jose P., Leiner, Tim, Planken, R. Nils, and Isgum, Ivana

Abstract

Coronary artery disease (CAD) remains the leading cause of death worldwide. Patients with suspected CAD undergo coronary CT angiography (CCTA) to evaluate the risk of cardiovascular events and determine the treatment. Clinical analysis of coronary arteries in CCTA comprises the identification of atherosclerotic plaque, as well as the grading of any coronary artery stenosis typically obtained through the CAD-Reporting and Data System (CAD-RADS). This requires analysis of the coronary lumen and plaque. While voxel-wise segmentation is a commonly used approach in various segmentation tasks, it does not guarantee topologically plausible shapes. To address this, in this work, we propose to directly infer surface meshes for coronary artery lumen and plaque based on a centerline prior and use it in the downstream task of CAD-RADS scoring. The method is developed and evaluated using a total of 2407 CCTA scans. Our method achieved lesion-wise volume intraclass correlation coefficients of 0.98, 0.79, and 0.85 for calcified, non-calcified, and total plaque volume respectively. Patient-level CAD-RADS categorization was evaluated on a representative hold-out test set of 300 scans, for which the achieved linearly weighted kappa ( $\kappa $ ) was 0.75. CAD-RADS categorization on the set of 658 scans from another hospital and scanner led to a $\kappa $ of 0.71. The results demonstrate that direct inference of coronary artery meshes for lumen and plaque is feasible, and allows for the automated prediction of routinely performed CAD-RADS categorization.

Published
2024
Full Text
View/download PDF

23. Aortic calcification: A postmortem CT validation study in a middle-aged population

Author

Vos, Annelotte, Houben, Ignas B., Celeng, Csilla, Takx, Richard A. P., Isgum, Ivana, Mali, Willem P. T. M., Vink, Aryan, de Jong, Pim A., Radiology and Nuclear Medicine, Biomedical Engineering and Physics, ACS - Atherosclerosis & ischemic syndromes, and Amsterdam Neuroscience - Brain Imaging

Subjects
Intimal lesions, Radiology, Nuclear Medicine and imaging, General Medicine, Abdominal aorta, Calcifications, Atherosclerosis
Abstract

Background: Computed tomography (CT)-detected aortic calcification is strongly associated with aortic stiffness and is an accurate predictor of cardiovascular and all-cause mortality and cognitive decline. Some previous pathologic studies have shown calcium accumulation in the medial layer of the vessel wall, while others have suggested localisation in the atherosclerotic intimal layer. Objectives: The aim of this study was to histologically validate CT findings of aortic calcification for detectability and location in the aortic wall. Methods: We acquired postmortem CT images and collected 170 aortic tissue samples from five different locations in the thoracic and abdominal aorta of 40 individuals who underwent autopsy. Microscopic slides were stained with haematoxylin and eosin and elastic van Gieson stain. Calcified lesions were characterised and calcifications were manually annotated in the intima and media. The presence and morphology of calcifications were scored on CT images. Results: The mean age of the autopsied individuals was 63 years, and 28 % died of cardiovascular disease. Calcifications were present in 74/170 (44 %) samples. Calcification was more common in the abdominal aorta than in the thoracic aorta. In all samples with calcifications, 99 % were located in the intimal layer. Only 16/170 samples had a small amount of medial arterial calcification. The histological results showed an 85 % concordance for the presence or absence of CT calcifications. There was complete inter-method agreement for annularity of calcifications in 68 % of the samples (linear weighted kappa 0.68 (95 %CI 0.60–0.77). Conclusions: Aortic calcifications visible on CT are located in the intimal layer of the abdominal aorta wall, at least in aortas that are not aneurysmatic or dissected. The presence and annularity of these calcifications can be reliably determined by CT.

Published
2022

31. Radiography and Computed Tomography Detection of Intimal and Medial Calcifications in Leg Arteries in Comparison to Histology

Author

Pathologie Pathologen staf, Circulatory Health, Onderzoek Beeld, MS Radiologie, Brain, Cancer, Anatomie, Researchgr. Systems Radiology, Infection & Immunity, Regenerative Medicine and Stem Cells, Vos, Annelotte, Vink, Aryan, Kockelkoren, Remko, Takx, Richard A P, Celeng, Csilla, Mali, Willem P T M, Isgum, Ivana, Bleys, Ronald L A W, de Jong, Pim A, Pathologie Pathologen staf, Circulatory Health, Onderzoek Beeld, MS Radiologie, Brain, Cancer, Anatomie, Researchgr. Systems Radiology, Infection & Immunity, Regenerative Medicine and Stem Cells, Vos, Annelotte, Vink, Aryan, Kockelkoren, Remko, Takx, Richard A P, Celeng, Csilla, Mali, Willem P T M, Isgum, Ivana, Bleys, Ronald L A W, and de Jong, Pim A

Published
2022

33. Pulmonary function and CT biomarkers as risk factors for cardiovascular events in male lung cancer screening participants: the NELSON study

Author

Takx, Richard A. P., Vliegenthart, Rozemarijn, Hoesein, Firdaus A. A. Mohamed, Išgum, Ivana, de Koning, Harry J., Mali, Willem P. Th. M., van der Aalst, Carlijn M., Zanen, Pieter, Lammers, Jan-Willem J., Groen, Harry J. M., van Rikxoort, Eva M., Schmidt, Michael, van Ginneken, Bram, Oudkerk, Matthijs, Leiner, Tim, and de Jong, Pim A.

Published
2015
Full Text
View/download PDF

40. Coronary CT angiography: image quality, diagnostic accuracy, and potential for radiation dose reduction using a novel iterative image reconstruction technique—comparison with traditional filtered back projection

Author

Moscariello, Antonio, Takx, Richard A. P., Schoepf, U. Joseph, Renker, Matthias, Zwerner, Peter L., O’Brien, Terrence X., Allmendinger, Thomas, Vogt, Sebastian, Schmidt, Bernhard, Savino, Giancarlo, Fink, Christian, Bonomo, Lorenzo, and Henzler, Thomas

Published
2011
Full Text
View/download PDF

42. Early detection of small volume stroke and thromboembolic sources with computed tomography: Rationale and design of the ENCLOSE study

Author

Kauw, Frans, Ommen, Fasco van, Bennink, Edwin, Cramer, Maarten J., Kappelle, L. Jaap, Takx, Richard A. P., Velthuis, Birgitta K., Viergever, Max A., Wouter van Es, H., Schonewille, Wouter J., Coutinho, Jonathan M., Majoie, Charles B. LM, Marquering, Henk A., de Jong, Hugo W. AM, Dankbaar, Jan W., on behalf of the ENCLOSE investigators, Neurology, ACS - Atherosclerosis & ischemic syndromes, Amsterdam Neuroscience - Neurovascular Disorders, Radiology and Nuclear Medicine, and ACS - Microcirculation

Subjects
medicine.medical_specialty, Lacunar stroke, Acute ischemic stroke, cardiac thrombus, detection, recurrent stroke, Early detection, Computed tomography, 030204 cardiovascular system & hematology, 03 medical and health sciences, 0302 clinical medicine, Protocol, medicine, magnetic resonance imaging, cardiovascular diseases, Stroke, Acute stroke, medicine.diagnostic_test, business.industry, Small volume, Magnetic resonance imaging, computed tomography, lacunar stroke, medicine.disease, prediction model, Neurology (clinical), Radiology, Tomography, Cardiology and Cardiovascular Medicine, business, 030217 neurology & neurosurgery
Abstract

Background Computed tomography is the most frequently used imaging modality in acute stroke imaging protocols. Detection of small volume infarcts in the brain and cardioembolic sources of stroke is difficult with current computed tomography protocols. Furthermore, the role of computed tomography findings to predict recurrent ischemic stroke is unclear. With ENCLOSE, we aim to improve (1) the detection of small volume infarcts with thin slice computed tomography perfusion (CTP) images and thromboembolic source with cardiac computed tomography techniques in the acute stage of ischemic stroke and (2) prediction of recurrent ischemic stroke with computed tomography-derived predictors. Methods/design: ENCLOSE is a prospective multicenter observational cohort study, which will be conducted in three Dutch stroke centers (ClinicalTrials.gov Identifier: NCT04019483). Patients (≥18 years) with suspected acute ischemic stroke who undergo computed tomography imaging within 9 h after symptom onset are eligible. Computed tomography imaging includes non-contrast CT, CTP, and computed tomography angiography (CTA) from base of the heart to the top of the brain. Dual-energy CT data will be acquired when possible, and thin-slice CTP reconstructions will be obtained in addition to standard 5 mm CTP data. CTP data will be processed with commercially available software and locally developed model-based methods. The post-processed thin-slice CTP images will be compared to the standard CTP images and to magnetic resonance diffusion-weighted imaging performed within 48 h after admission. Detection of cardioembolic sources of stroke will be evaluated on the CTA images. Recurrence will be evaluated 90 days and two years after the index event. The added value of imaging findings to prognostic models for recurrent ischemic stroke will be evaluated. Conclusion The aim of ENCLOSE is to improve early detection of small volume stroke and thromboembolic sources and to improve prediction of recurrence in patients with acute ischemic stroke.

Published
2020

44. Determinants of F-18-NaF uptake in femoral arteries in patients with type 2 diabetes mellitus

Author

Cancer, Arts-assistenten Radiologie, Fysica Radiologie, Researchgr. Systems Radiology, Cardiovasculaire Epi Team 1, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Beeldverwerking ISI, Researchgr. Cardiovasculaire Radiologie, Infection & Immunity, Regenerative Medicine and Stem Cells, Takx, Richard A P, van Asperen, Ruth, Bartstra, Jonas W, Zwakenberg, Sabine R, Wolterink, Jelmer M, Celeng, Csilla, de Jong, Pim A, Beulens, Joline W, Cancer, Arts-assistenten Radiologie, Fysica Radiologie, Researchgr. Systems Radiology, Cardiovasculaire Epi Team 1, Circulatory Health, JC onderzoeksprogramma Cardiovasculaire Epidemiologie, Beeldverwerking ISI, Researchgr. Cardiovasculaire Radiologie, Infection & Immunity, Regenerative Medicine and Stem Cells, Takx, Richard A P, van Asperen, Ruth, Bartstra, Jonas W, Zwakenberg, Sabine R, Wolterink, Jelmer M, Celeng, Csilla, de Jong, Pim A, and Beulens, Joline W

Published
2021

49. The Association Between Marital Status, Coronary Computed Tomography Imaging Biomarkers, and Mortality in a Lung Cancer Screening Population

Author

Researchgr. Cardiovasculaire Radiologie, Arts-assistenten Radiologie, Fysica Radiologie, Beeldverwerking ISI, Circulatory Health, Cancer, Brain, Researchgr. Systems Radiology, Regenerative Medicine and Stem Cells, Infection & Immunity, Celeng, Csilla, Takx, Richard A P, Lessmann, Nikolas, Maurovich-Horvat, Pál, Leiner, Tim, Išgum, Ivana, de Jong, Pim A, Researchgr. Cardiovasculaire Radiologie, Arts-assistenten Radiologie, Fysica Radiologie, Beeldverwerking ISI, Circulatory Health, Cancer, Brain, Researchgr. Systems Radiology, Regenerative Medicine and Stem Cells, Infection & Immunity, Celeng, Csilla, Takx, Richard A P, Lessmann, Nikolas, Maurovich-Horvat, Pál, Leiner, Tim, Išgum, Ivana, and de Jong, Pim A

Published
2020

Catalog

Books, media, physical & digital resources
See catalog results