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4. [A case of large-cell lung cancer with liver metastasis successfully treated using combination chemotherapy with CDDP and vinorelbine].

Author

Katsuki S, Kitaoka K, Takizawa K, Machida T, Oku T, Sumiyoshi T, Nagamachi Y, Inomata H, Nojiri S, Nishino M, Fujita M, and Niitsu Y

Subjects
Adult, Carcinoma, Large Cell secondary, Cisplatin administration & dosage, Drug Administration Schedule, Female, Humans, Liver Neoplasms secondary, Lung Neoplasms pathology, Vinblastine administration & dosage, Vinorelbine, Antineoplastic Combined Chemotherapy Protocols therapeutic use, Carcinoma, Large Cell drug therapy, Liver Neoplasms drug therapy, Lung Neoplasms drug therapy, Vinblastine analogs & derivatives
Abstract

A 38-year-old woman presented to our hospital with the chief complaint of dyspnea. A chest radiograph showed pleural effusion of the right lung and a CT scan revealed liver metastasis. A tumor biopsy done under bronchoscopy revealed large-cell carcinoma of the lungs. She was given 4 courses of a combination therapy consisting of CDDP (80 mg/m2) and vinorelbine (25 mg/m2). The primary tumor in the right lung and liver metastasis were markedly reduced in size and a partial response was obtained. The combination therapy of CDDP and vinorelbine may become a standard chemotherapy for advanced non-small cell lung cancer.

Published
2002

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