31 results on '"Takita W"'
Search Results
2. The development of visual task management ICT system for acute stroke care
- Author
-
Matsumoto, S., primary, Koyama, H., additional, Hatano, T., additional, Sadamasa, N., additional, Kai, Y., additional, Saka, M., additional, Ando, M., additional, Hashimoto, T., additional, Chihara, H., additional, Takita, W., additional, Tokunaga, K., additional, Kamata, T., additional, Tujimoto, A., additional, Nagata, I., additional, and Kira, J.I., additional
- Published
- 2017
- Full Text
- View/download PDF
3. Reduction in stroke alert response time for patients with in-hospital stroke using a standardized protocol
- Author
-
Koge, J., primary, Matsumoto, S., additional, Nakahara, I., additional, Ishii, A., additional, Hatano, T., additional, Sadamasa, N., additional, Kai, Y., additional, Ando, M., additional, Saka, M., additional, Chihara, H., additional, Takita, W., additional, Tokunaga, K., additional, Kamata, T., additional, Nishi, H., additional, Hashimoto, T., additional, Tsujimoto, A., additional, Kira, J.I., additional, and Nagata, I., additional
- Published
- 2017
- Full Text
- View/download PDF
4. Schemes on the home front
- Author
-
Mason, Takita W.
- Subjects
Fraud -- Cases -- Public opinion ,Home labor -- Public opinion -- Cases ,Business, general ,Business ,Ethnic, cultural, racial issues/studies ,Company legal issue ,Cases ,Public opinion - Abstract
In-house employment opportunities don't pan out You have probably seen this ad in one of your local newspapers: '$356 Weekly Guaranteed. Work two hours daily at home stuffing envelopes. No [...]
- Published
- 2000
5. A classic dilemma
- Author
-
Mason, Takita W.
- Subjects
Employee selection -- Analysis ,College graduates -- Employment ,Employment interviewing -- Analysis ,Business, general ,Business ,Ethnic, cultural, racial issues/studies ,Hiring ,Analysis ,Employment - Abstract
Get past it and get your first gig So you finished your undergraduate education in May and you're still on the prowl for your first job. Apparently, you've been running [...]
- Published
- 2000
6. Packet Size Based Routing for Stable Data Delivery in Mobile Ad-Hoc Networks
- Author
-
KHAN, A., primary, SUZUKI, T., additional, KOBAYASHI, M., additional, TAKITA, W., additional, and YAMAZAKI, K., additional
- Published
- 2008
- Full Text
- View/download PDF
7. Proactive Cooperation Mechanism against Selfish Power Off for Mobile Ad Hoc Networks
- Author
-
SUZUKI, T., primary, KHAN, A., additional, and TAKITA, W., additional
- Published
- 2007
- Full Text
- View/download PDF
8. Collaboration in Routing and Velocity Measurement Function for Mobile Ad hoc Networks.
- Author
-
Suzuki, T., Khan, A., Kobayashi, M., and Takita, W.
- Published
- 2007
- Full Text
- View/download PDF
9. Hepatectomy and Intraarterial Infusion Chemotherapy for Liver Metastasis from Colorectal Cancer.
- Author
-
Nakazaki, H., primary, Watanabe, M., additional, Hasebe, Y., additional, Suzuki, Y., additional, Ohshiro, M., additional, Takita, W., additional, Seo, A., additional, Shimojima, Y., additional, Funahashi, K., additional, Tsujita, K., additional, Kobayashi, K., additional, and Yoshio, T., additional
- Published
- 1999
- Full Text
- View/download PDF
10. OMG A/V streams and TINA NRA: an integrative approach
- Author
-
Kath, O., primary and Takita, W., additional
- Published
- 1999
- Full Text
- View/download PDF
11. Evaluation of Hepatic Resection for Colorectal Cancer Patients with Liver Metastasis.
- Author
-
Watanabe, M., primary, Nakazaki, H., additional, Maeda, T., additional, Hanawa, S., additional, Hasebe, Y., additional, Ohoshiro, T., additional, Takita, W., additional, Seo, A., additional, Nagasawa, Y., additional, Tsujita, K., additional, Yanagita, K., additional, Kuramoto, S., additional, and Yoshio, T., additional
- Published
- 1995
- Full Text
- View/download PDF
12. Quench propagation analysis in adiabatic superconducting windings
- Author
-
Ishiyama, A., primary, Matsumura, H., additional, Takita, W., additional, and Iwasa, Y., additional
- Published
- 1991
- Full Text
- View/download PDF
13. TINA connection management implementation over distributed processing platforms.
- Author
-
Spinelli, G., Takita, W., Martini, C., and Chikara, S.
- Published
- 1996
- Full Text
- View/download PDF
14. Clopidogrel response predicts thromboembolic events associated with coil embolization of unruptured intracranial aneurysms: A prospective cohort study.
- Author
-
Higashi E, Matsumoto S, Nakahara I, Hatano T, Ishii A, Sadamasa N, Ohta T, Ishihara T, Tokunaga K, Ando M, Chihara H, Furuta K, Hashimoto T, Tanaka K, Sonoda K, Koge J, Takita W, Hashikawa T, Funakoshi Y, Kondo D, Kamata T, Tsujimoto A, Matsushita T, Murai H, Matsuo K, Kitazono T, and Kira J
- Subjects
- Aged, Female, Humans, Male, Middle Aged, Prospective Studies, Blood Vessel Prosthesis adverse effects, Clopidogrel therapeutic use, Embolization, Therapeutic adverse effects, Intracranial Aneurysm therapy, Platelet Aggregation Inhibitors therapeutic use, Thromboembolism prevention & control
- Abstract
Objective: Periprocedural thromboembolic events are a serious complication associated with coil embolization of unruptured intracranial aneurysms. However, no established clinical rule for predicting thromboembolic events exists. This study aimed to clarify the significance of adding preoperative clopidogrel response value to clinical factors when predicting the occurrence of thromboembolic events during/after coil embolization and to develop a nomogram for thromboembolic event prediction., Methods: In this prospective, single-center, cohort study, we included 345 patients undergoing elective coil embolization for unruptured intracranial aneurysm. Thromboembolic event was defined as the occurrence of intra-procedural thrombus formation and postprocedural symptomatic cerebral infarction within 7 days. We evaluated preoperative clopidogrel response and patients' clinical information. We developed a patient-clinical-information model for thromboembolic event using multivariate analysis and compared its efficiency with that of patient-clinical-information plus preoperative clopidogrel response model. The predictive performances of the two models were assessed using area under the receiver-operating characteristic curve (AUC-ROC) with bootstrap method and compared using net reclassification improvement (NRI) and integrated discrimination improvement (IDI)., Results: Twenty-eight patients experienced thromboembolic events. The clinical model included age, aneurysm location, aneurysm dome and neck size, and treatment technique. AUC-ROC for the clinical model improved from 0.707 to 0.779 after adding the clopidogrel response value. Significant intergroup differences were noted in NRI (0.617, 95% CI: 0.247-0.987, p < .001) and IDI (0.068, 95% CI: 0.021-0.116, p = .005)., Conclusions: Evaluation of preoperative clopidogrel response in addition to clinical variables improves the prediction accuracy of thromboembolic event occurrence during/after coil embolization of unruptured intracranial aneurysm., Competing Interests: The authors have declared that no competing interests exist.
- Published
- 2021
- Full Text
- View/download PDF
15. Mechanical Thrombectomy for Azygos Anterior Cerebral Artery Occlusion: A Case Report and Literature Review.
- Author
-
Asai T, Oyama T, Takita W, Ohno M, Suzaki N, Kajita Y, and Takahashi T
- Abstract
Objective: Azygos anterior cerebral artery (ACA) is a well-known anomaly of the second segment of the ACA. Although cases of intracerebral aneurysms related to this anomaly have been reported, acute ischemic stroke (AIS) related to the azygos ACA is extremely rare., Case Presentation: An 84-year-old man developed disturbance of consciousness (Glasgow Coma Scale [GCS] E3V1M5), quadriparesis and aphasia, with a National Institutes of Health Stroke Scale (NIHSS) score of 32. Magnetic resonance imaging (MRI) showed no early ischemic changes, although a head magnetic resonance angiogram (MRA) demonstrated a single A2 trunk without any A3 branches that were suspected bilateral ACA occlusions. Mechanical thrombectomy for the occluded A2 trunk with contact aspiration using a Penumbra 4MAX aspiration catheter was performed, and the clot was retrieved and complete recanalization was achieved after two attempts (Thrombolysis in Cerebral Infarction scale 3) without any complications (onset to recanalization time: 187 min). The final angiogram demonstrated the recanalization of the single A2 and bilateral A3 branches, so we diagnosed as azygos ACA occlusion. MRI performed the next day revealed several small infarctions in bilateral frontal lobes, but ischemic symptoms gradually improved. NIHSS score decreased to two in 2 weeks and modified Rankin Scale (mRS) score at 90 days was one., Conclusion: In this case, occlusion of the azygos ACA led to a large ischemic penumbra that spread widely and bilaterally in the ACA area, resulting in sudden onset of severe ischemic symptoms, including quadriparesis and aphasia. However, due to complete and rapid recanalization with contract aspiration, a large part of the ACA territory bilaterally was salvaged and the patient recovered extremely well., Competing Interests: None of the authors have conflicts of interest in relation to this article., (©2021 The Japanese Society for Neuroendovascular Therapy.)
- Published
- 2021
- Full Text
- View/download PDF
16. Intracranial Subdural Abscess Caused by Actinomyces meyeri Related to Dental Treatment: A Case Report.
- Author
-
Funakoshi Y, Hatano T, Ando M, Chihara H, Takita W, Tokunaga K, Hashikawa T, Kamata T, Higashi E, and Nagata I
- Abstract
Intracranial subdural abscess is a rare condition. Although brain abscess is often reported in relation to dental infection, reports of intracranial subdural abscess are few. Actinomyces spp. forms part of the normal flora of the oral, gastrointestinal, and genital tract, and is rarely the cause of intracranial infection; moreover, the pathogen Actinomyces meyeri is very rare. We report an exceptional case of intracranial subdural abscess caused by A. meyeri and related to dental treatment. A 57-year-old woman initially presented with a 5-day history of headache. Because left arm numbness and weakness became apparent, she was admitted to our department. She had a history of hypertension and dental problems requiring tooth extractions. Diffusion-weighted imaging (DWI) showed a 1-cm right convexity hyperintense mass above the postcentral gyrus. A post-gadolinium T1-weighted image showed a thin hypointense area with peripheral rim enhancement in the right subdural space that appeared to partially thicken in the same location as the DWI-positive mass. She underwent emergent navigation-guided drainage and 4 mL of pus was obtained. Postoperatively, left arm numbness and weakness disappeared. Cultures showed growth of A. meyeri and Fusobacterium nucleatum . She was started on intravenous penicillin G and metronidazole. After a 4-week course of the intravenous antibiotics, her headache gradually improved and the abscess in the subdural space subsided. To our best knowledge this is the first case report of intracranial subdural abscess caused by A. meyeri associated with dental treatment., Competing Interests: Conflicts of Interest Disclosure The authors report no competing interests concerning the materials or methods used in this study or the findings specified in this paper., (© 2020 The Japan Neurosurgical Society.)
- Published
- 2020
- Full Text
- View/download PDF
17. A Visual Task Management Application for Acute Ischemic Stroke Care.
- Author
-
Matsumoto S, Koyama H, Nakahara I, Ishii A, Hatano T, Ohta T, Tanaka K, Ando M, Chihara H, Takita W, Tokunaga K, Hashikawa T, Funakoshi Y, Kamata T, Higashi E, Watanabe S, Kondo D, Tsujimoto A, Furuta K, Ishihara T, Hashimoto T, Koge J, Sonoda K, Torii T, Nakagaki H, Yamasaki R, Nagata I, and Kira JI
- Abstract
Background: To maximize the effect of intravenous (IV) thrombolysis and/or endovascular therapy (EVT) for acute ischemic stroke (AIS), stroke centers need to establish a parallel workflow on the basis of a code stroke (CS) protocol. At Kokura Memorial Hospital (KMH), we implemented a CS system in January 2014; however, the process of information sharing within the team has occasionally been burdensome. Objective: To solve this problem using information communication technology (ICT), we developed a novel application for smart devices, named "Task Calc. Stroke" (TCS), and aimed to investigate the impact of TCS on AIS care. Methods: TCS can visualize the real-time progress of crucial tasks for AIS on a dashboard by changing color indicators. From August 2015 to March 2017, we installed TCS at KMH and recommended its use during normal business hours (NBH). We compared the door-to-computed tomography time, the door-to-complete blood count (door-to-CBC) time, the door-to-needle for IV thrombolysis time, and the door-to-puncture for EVT time among three treatment groups, one using TCS ("TCS-based CS"), one not using TCS ("phone-based CS"), and one not based on CS ("non-CS"). A questionnaire survey regarding communication problems was conducted among the CS teams at 3 months after the implementation of TCS. Results: During the study period, 74 patients with AIS were transported to KMH within 4.5 h from onset during NBH, and 53 were treated using a CS approach (phone-based CS: 26, TSC-based CS: 27). The door-to-CBC time was significantly reduced in the TCS-based CS group compared to the phone-based CS group, from 31 to 19 min ( p = 0.043). Other processing times were also reduced, albeit not significantly. The rate of IV thrombosis was higher in the TCS-based CS group (78% vs. 46%, p = 0.037). The questionnaire was correctly filled in by 34/38 (89%) respondents, and 82% of the respondents felt a reduction in communication burden by using the TCS application. Conclusions: TCS is a novel approach that uses ICT to support information sharing in a parallel CS workflow in AIS care. It shortens the processing times of critical tasks and lessens the communication burden among team members., (Copyright © 2019 Matsumoto, Koyama, Nakahara, Ishii, Hatano, Ohta, Tanaka, Ando, Chihara, Takita, Tokunaga, Hashikawa, Funakoshi, Kamata, Higashi, Watanabe, Kondo, Tsujimoto, Furuta, Ishihara, Hashimoto, Koge, Sonoda, Torii, Nakagaki, Yamasaki, Nagata and Kira.)
- Published
- 2019
- Full Text
- View/download PDF
18. Factors Associated with Postprocedural Diffusion-Weighted Imaging-Positive Lesions in Endovascular Treatment for Unruptured Cerebral Aneurysms.
- Author
-
Tokunaga K, Hatano T, Nakahara I, Ishii A, Higashi E, Kamata T, Funakoshi Y, Hashikawa T, Takita W, Chihara H, Ando M, Sadamasa N, Kitazono T, and Nagata I
- Subjects
- Aged, Female, Humans, Male, Middle Aged, Postoperative Complications diagnostic imaging, Diffusion Magnetic Resonance Imaging, Endovascular Procedures adverse effects, Intracranial Aneurysm surgery, Postoperative Complications etiology, Thromboembolism diagnostic imaging, Thromboembolism etiology
- Abstract
Background: In endovascular treatment for cerebral aneurysms, the appearance of asymptomatic thromboembolic lesions detected by postprocedural diffusion-weighted imaging (DWI) can be a surrogate marker for estimating the potential risk of symptomatic thromboembolism. The aim of this study was to clarify factors associated with postprocedural DWI-positive lesions in endovascular treatment for unruptured cerebral aneurysms., Methods: Patients with untreated unruptured cerebral aneurysms undergoing endovascular treatment were consecutively enrolled. Treatment techniques were classified into simple coiling, balloon-assisted coiling, stent-assisted coiling, and flow-diverter placement. Head magnetic resonance imaging was performed within 3 months before and 24 hours after the procedure to assess the appearance of DWI-positive lesions., Results: Among 376 aneurysms in 355 patients that were analyzed, 232 (61.7%) had postprocedural DWI-positive lesions. In univariate analyses, age (P = 0.001), dome size (P < 0.001), neck size (P < 0.001), treatment technique (P = 0.029), and total procedural time (P < 0.001) were significantly associated with postprocedural DWI-positive lesions. In the multiple logistic regression model, older age (odds ratio, 1.33; 95% confidence interval, 1.10-1.60; P = 0.003; per decade), flow-diverter placement (odds ratio, 4.93; 95% confidence interval, 1.33-20.92; P = 0.016; compared with simple coiling), and longer procedural time (odds ratio, 1.66; 95% confidence interval, 1.26-2.21; P < 0.001; per hour) were associated with postprocedural DWI-positive lesions., Conclusions: Older age, flow-diverter placement, and longer procedural time were associated with postprocedural DWI-positive lesions in endovascular treatment for unruptured cerebral aneurysms., (Copyright © 2019 Elsevier Inc. All rights reserved.)
- Published
- 2019
- Full Text
- View/download PDF
19. A Case of Posterior Reversible Encephalopathy Syndrome After Surgical Clipping of Unruptured Cerebral Aneurysm.
- Author
-
Chihara H, Hatano T, Ando M, Takita W, Tokunaga K, Hashikawa T, Funakoshi Y, Kamata T, Higashi E, and Nagata I
- Abstract
Background: Posterior reversible encephalopathy syndrome (PRES) is characterized by reversible edematous lesions on imaging examinations, along with symptoms of altered consciousness disorder and seizures. Various factors associated with PRES have been reported. However, we encountered a very rare case that developed after clipping surgery for unruptured cerebral aneurysm., Case Description: A 74-year-old man with a history of hypertension presented with an unruptured right middle cerebral artery aneurysm and underwent cranial clipping surgery. After surgery, he developed consciousness disorder and epilepsy after delayed awakening from general anesthesia. Radiological examinations revealed multiple edematous lesions, strongly suggesting PRES, and excluding asymmetry consistent with the area of craniotomy. With conservative treatment, symptoms and radiological findings almost disappeared. Symptoms and imaging findings remaining at the area of craniotomy were attributed to the severe difference in cerebral perfusion pressure due to craniotomy., Conclusions: Based on the literature, this case was considered to represent PRES caused by rapid blood pressure fluctuations accompanying general anesthesia for clipping surgery. Practitioners must keep PRES in mind as a rare complication after clipping for unruptured cerebral aneurysms. PRES developing after craniotomy shows unilaterality and may become severe in the craniotomy area and leave sequelae., (Copyright © 2019 Elsevier Inc. All rights reserved.)
- Published
- 2019
- Full Text
- View/download PDF
20. Dural and Pial Arteriovenous Fistulas Connected to the Same Drainer in the Middle Cranial Fossa: A Case Report.
- Author
-
Funakoshi Y, Hatano T, Saka M, Ando M, Chihara H, Takita W, Tokunaga K, Hashikawa T, Kamata T, Higashi E, and Nagata I
- Subjects
- Arteriovenous Fistula complications, Arteriovenous Fistula surgery, Central Nervous System Vascular Malformations complications, Central Nervous System Vascular Malformations diagnostic imaging, Central Nervous System Vascular Malformations surgery, Cranial Fossa, Middle surgery, Humans, Intracranial Arteriovenous Malformations complications, Intracranial Arteriovenous Malformations surgery, Male, Middle Aged, Pia Mater surgery, Skull Base Neoplasms complications, Skull Base Neoplasms surgery, Arteriovenous Fistula diagnostic imaging, Cranial Fossa, Middle diagnostic imaging, Intracranial Arteriovenous Malformations diagnostic imaging, Pia Mater diagnostic imaging, Skull Base Neoplasms diagnostic imaging
- Abstract
Background: Dural arteriovenous fistulas (AVFs) in the middle cranial fossa are rare. Pial AVFs are similarly rare but differ from dural AVFs in that they derive their arterial supply from pial or cortical arterial vessels and do not lie within the intradural region. We report an extremely rare case of dural and pial AVF connected to the same drainer in the middle cranial fossa., Case Description: In a 58-year-old man with a subcortical hemorrhage in the right temporal lobe, digital subtraction angiography showed a dural AVF in the middle cranial fossa fed by the middle meningeal artery (MMA) and draining into the sphenopetrosal vein. A combination with a small pial AVF connected to the same sphenopetrosal vein was suspected. Open surgery was performed to directly observe the shunt points. Transarterial indocyanine green (ICG) angiography using the MMA via the superficial temporal artery on a skin flap was performed to repeatedly and distinctly evaluate the dural shunt points and to prevent cerebral thromboembolism. Although the dural supply was completely disconnected, the sphenopetrosal vein remained arterialized. ICG angiography revealed pial AVF, which was fed by the cortical arteries draining into the same drainer. The pial supply was completely disconnected, and disappearance of the dural and pial AVF was confirmed., Conclusions: We report an extremely rare case of dural and pial AVF connected to the same drainer in the middle cranial fossa. To our knowledge, this is the first such case report described in the literature., (Copyright © 2018 Elsevier Inc. All rights reserved.)
- Published
- 2018
- Full Text
- View/download PDF
21. Improving treatment times for patients with in-hospital stroke using a standardized protocol.
- Author
-
Koge J, Matsumoto S, Nakahara I, Ishii A, Hatano T, Sadamasa N, Kai Y, Ando M, Saka M, Chihara H, Takita W, Tokunaga K, Kamata T, Nishi H, Hashimoto T, Tsujimoto A, Kira JI, and Nagata I
- Subjects
- Administration, Intravenous, Aged, Endovascular Procedures, Female, Health Personnel education, Humans, Male, Neuroimaging, Retrospective Studies, Stroke diagnostic imaging, Thrombolytic Therapy, Treatment Outcome, Clinical Protocols standards, Hospitalization, Quality Improvement, Stroke therapy, Time-to-Treatment
- Abstract
Background: Previous reports have shown significant delays in treatment of in-hospital stroke (IHS). We developed and implemented our IHS alert protocol in April 2014. We aimed to determine the influence of implementation of our IHS alert protocol., Methods: Our implementation processes comprise the following four main steps: IHS protocol development, workshops for hospital staff to learn about the protocol, preparation of standardized IHS treatment kits, and obtaining feedback in a monthly hospital staff conference. We retrospectively compared protocol metrics and clinical outcomes of patients with IHS treated with intravenous thrombolysis and/or endovascular therapy between before (January 2008-March 2014) and after implementation (April 2014-December 2016)., Results: Fifty-five patients were included (pre, 25; post, 30). After the implementation, significant reductions occurred in the median time from stroke recognition to evaluation by a neurologist (30 vs. 13.5min, p<0.01) and to first neuroimaging (50 vs. 26.5min, p<0.01) and in the median time from first neuroimaging to intravenous thrombolysis (45 vs. 16min, p=0.02). The median time from first neuroimaging to endovascular therapy had a tendency to decrease (75 vs. 53min, p=0.08). There were no differences in the favorable outcomes (modified Rankin scale score of 0-2) at discharge or the incidence of symptomatic intracranial hemorrhage between the two periods., Conclusion: Our IHS alert protocol implementation saved time in treating patients with IHS without compromising safety., (Copyright © 2017 Elsevier B.V. All rights reserved.)
- Published
- 2017
- Full Text
- View/download PDF
22. [Case report of a liver metastasis from rectal cancer achieving complete response (CR) by a combination of intra-hepatic arterial infusion of irinotecan (CPT-11) with degradable starch microspheres (DSM) and weekly high-dose intra-hepatic arterial chemotherapy with 5-FU].
- Author
-
Watanabe M, Tsuchiya M, Takita W, Otsuka Y, Tamura A, Yamazaki K, Koshino H, Kurihara A, Kaneko H, and Teramoto T
- Subjects
- Aged, Camptothecin administration & dosage, Camptothecin analogs & derivatives, Drug Administration Schedule, Female, Fluorouracil administration & dosage, Hepatic Artery, Humans, Infusion Pumps, Implantable, Infusions, Intra-Arterial, Irinotecan, Mitomycin administration & dosage, Rectal Neoplasms pathology, Starch administration & dosage, Adenocarcinoma drug therapy, Adenocarcinoma secondary, Antineoplastic Combined Chemotherapy Protocols therapeutic use, Liver Neoplasms drug therapy, Liver Neoplasms secondary, Rectal Neoplasms drug therapy
- Abstract
A 67-year-old woman, who was diagnosed with rectal cancer and liver metastasis, underwent a low anterior resection of the rectum in May 2004. Two months later, the level of tumor markers increased and a CT scan revealed a 45 x 35 mm liver metastasis in the S(8) segment. She was referred to our hospital for treatment of the liver tumor. Intra-hepatic arterial infusion of irinotecan (CPT-11) and mitomycin C (MMC) with degradable starch microspheres (DSM) was given in July 2004. Following this, a 34-week course of weekly high-dose intra-hepatic arterial 5-FU infusion (5-FU 1,000 mg/m(2)) was performed. In April 2005, the size of the liver metastasis decreased, and the level of serum tumor marker normalized. A CT and echo scan revealed a calcified tumor, and therefore all chemotherapy was stopped. She was followed in the outpatient clinic, with no evidence of recurrence for 12 months. This case suggests that the use of intra-hepatic arterial infusion of CPT-11 and MMC with DSM is useful for the treatment of liver metastases in colorectal cancer.
- Published
- 2006
23. [Cryotherapy of the resection edge after hepatectomy of colorectal liver metastases].
- Author
-
Watanabe M, Kaneko H, Takita W, Otsuka Y, Tsuchiya M, Tamura A, Maeda T, Oshima Y, Kobayashi K, and Teramoto T
- Subjects
- Combined Modality Therapy, Humans, Liver Neoplasms pathology, Male, Middle Aged, Postoperative Complications, Colorectal Neoplasms pathology, Cryosurgery methods, Hepatectomy, Liver Neoplasms secondary, Liver Neoplasms therapy, Neoplasm Recurrence, Local prevention & control
- Abstract
Obtaining a one-centimeter negative margin is an important factor in preventing disease recurrence after surgery for hepatic tumors. Cryotherapy of the resected edge has been used to achieve optimal margin clearance in cases in which the alternative would be an extended high-risk liver resection. As a concrete method, cryotherapy was delivered with a liquid nitrogen based compact system (CRY-AC, Brymill Co., USA). The resection edge with involved or inadequate resection margins was ablated directly by using the flat probe for 3 minutes per 1 place. Between 2002 and present, a total of 14 patients with colorectal liver metastases underwent edge cryotherapy. Although there was no hemorrhage from the stump, postoperative leak of the bile and stump recurrence were recognized in each patient. Since cryotherapy has features that make the vascular difficult to be damaged, the complication was not recognized in the patient with exposed vascular in the resected edge. By extending the follow-up period, we want to examine whether the edge recurrence could be controlled or not.
- Published
- 2005
24. Hepatic arterial cannulation using the side holed catheter.
- Author
-
Watanabe M, Takita W, Tsuchiya M, Otsuka Y, Tamura A, Kaneko H, and Kobayashi K
- Subjects
- Aged, Arterial Occlusive Diseases prevention & control, Equipment Design standards, Female, Humans, Infusions, Intra-Arterial, Laparotomy, Liver Neoplasms surgery, Male, Radiography, Catheters, Indwelling standards, Hepatic Artery diagnostic imaging, Infusion Pumps, Implantable, Liver Neoplasms drug therapy
- Abstract
Background: Hepatic arterial infusion chemotherapy (HAIC) has been recognized as one of the effective treatments for patients with hepatic metastatic tumor. However it is difficult to perform HAIC in the long term without complications. This report describes the laparotomic approach using the side holed catheter, which is a novel method of implanting a catheter-port system., Methods and Results: We designed a new anti-thrombotic catheter for HAIC. This catheter is tapered from 5F (diameter of shaft) to 3.3F (diameter at tip), and a side hole is opened 7 cm from the tip of catheter. This catheter is inserted from the gastroduodenal artery to the common hepatic artery (CHA), and the tip is put in the aorta or in the splenic artery. The side hole is adjusted distal to the CHA. In our surgical department, our new catheter was inserted in four patients at the time of their abdominal surgery. The cannulation was performed successfully in all patients. In two of them, HAIC was finished without problems at 6 months after starting, and two were still treated by HAIC at 9 and 8 months after starting., Conclusions: Initial results from a study of a new method of implanting a catheter-port system in the hepatic artery using the new tapering side hole catheter suggest that this method may enable operators to avoid complicated selective coiling and may lower the incidence of hepatic artery occlusion in patients receiving long-term HAIC., (Copyright 2005 Wiley-Liss, Inc.)
- Published
- 2005
- Full Text
- View/download PDF
25. Hepatic arterial catheterization combining interventional radiological and laparotomic approaches.
- Author
-
Watanabe M, Takita W, Nakazaki H, Tanemura H, Kaneko H, and Kobayashi K
- Subjects
- Epigastric Arteries surgery, Hepatic Artery, Humans, Infusions, Intra-Arterial, Laparoscopy, Laparotomy, Liver Neoplasms surgery, Catheterization, Peripheral instrumentation, Catheters, Indwelling, Coated Materials, Biocompatible, Liver Neoplasms drug therapy
- Abstract
Background and Objectives: This report describes a modified method of implanting a catheter-port system for hepatic arterial infusion chemotherapy (HAIC) that combines interventional radiological (IVR) and laparotomic approaches., Methods and Results: In patients, scheduled for HAIC and laparotomic surgery, we now employ a modified method of implanting the catheter-port system. In our method, an IVR approach is used to implant the catheter-port, and arterial occlusions are primarily carried out using a laparotomic approach. Following celiac and superior mesenteric arteriographies, a tapered microcatheter with a side hole is inserted by a catheter exchange method. The catheter tip is advanced far into the gastroepiploic artery via the gastroduodenal artery (GDA). The side hole is located at the orifice of the proper hepatic artery, and its location is confirmed by injection of contrast media. The microcatheter is connected to the port, and the port is buried in the subcutaneous pocket. During the laparotomy stage, the GDA lumen and the catheter lumen are clipped, and the right gastric artery (RGA) and all small branches supplying the stomach, duodenum, and pancreas are ligated. Among the 13 patients successfully implanted with a port-catheter system using our combined approach, no patients had hepatic artery occlusion or occlusion of the catheter system., Conclusions: Initial results from a study of a new method of implanting a microcatheter-port system in the hepatic artery using combined IVR and laparotomic approaches suggest that this method may enable operators to avoid complicated selective coiling and may lower the incidence of hepatic artery occlusion in patients receiving long-term HAIC.
- Published
- 2004
- Full Text
- View/download PDF
26. [The results of liver cryosurgery for synchronized liver metastasis from colorectal cancer].
- Author
-
Watanabe M, Nakazaki H, Takada M, Kurihara A, Takita W, Hasebe Y, Fujimoto T, Teramoto T, and Kobayashi K
- Subjects
- Adult, Aged, Colorectal Neoplasms surgery, Female, Humans, Liver Neoplasms immunology, Liver Neoplasms mortality, Male, Middle Aged, Survival Rate, Colorectal Neoplasms pathology, Cryosurgery, Hepatectomy methods, Liver Neoplasms secondary, Liver Neoplasms surgery
- Abstract
We examined our results of liver cryosurgery for synchronized liver metastasis from colorectal cancer. Twelve patients whose prognosis after the cryosurgery was clear were eligible. All of the patients received not only a resection of the colorectal primary lesion, but they also received a cryosurgery for liver metastases under the same laparotomy. These patients had been treated in this manner from 1981 to 1987. Ten of the 12 patients died from recurrent cancer. The range in survival time of 12 cases was from 6 months to 117 months, and the average survival length was 25.4 months. The examination of the results suggested that there were no cryosurgery induced anti-immunological response observed among the patients. The survival lengths of the patients with untreated cancer were good.
- Published
- 2004
27. Intraoperative packing of a pancreatic pseudocyst complicated with bleeding pseudoaneurysm.
- Author
-
Watanabe M, Nakazaki H, Tokura N, Takita W, and Kobayashi K
- Subjects
- Chronic Disease, Humans, Male, Middle Aged, Pancreatic Ducts, Rupture, Spontaneous, Tampons, Surgical, Aneurysm, False complications, Gastrointestinal Hemorrhage etiology, Pancreatic Pseudocyst complications, Pancreatic Pseudocyst surgery, Pancreatitis complications
- Abstract
Hemosuccus pancreaticus (HP) is a rare cause of gastrointestinal bleeding, usually due to rupture of a visceral artery aneurysm in chronic pancreatitis. Other causes of HP are rare. We present a case of HP which occurred in a patient with chronic calcifying pancreatitis and a pancreatic pseudocyst documented by ultrasonography and computed tomography. With detectable fresh blood in the descending duodenum, an aneurysm in the pancreatic head was revealed by superior mesenteric angiography as the suspected origin of intermittent bleeding from the pancreatic duct. Because an artery feeding the pseudocyst could not be identified, angiographic embolization was not possible. Surgical resection or ligation was difficult by laparotomy; therefore, intraoperative packing of the pseudocyst with absorbable gelatin sponges was achieved via a cannula through a directly punctured site in the pseudocyst wall. The patient has been followed for 4.25 years with no further episodes of HP. It is possible that the packing of a pancreatic pseudocyst with gelatin sponges is a method that can be used in similar cases, where control of hemostasis is the primary concern. The packing of a pancreatic pseudocyst with gelatin sponges is a technique that can be performed not only via laparotomy but also via laparoscopy or concomitant angiography and ultrasonography.
- Published
- 2004
- Full Text
- View/download PDF
28. [Hepatectomy and intraarterial infusion chemotherapy for liver metastasis from colorectal cancer].
- Author
-
Kurihara A, Nakazaki H, Watanabe M, Hasebe Y, Takita W, Seo A, Takata M, Kobayashi K, Teramoto T, and Hirano K
- Subjects
- Antimetabolites, Antineoplastic administration & dosage, Fluorouracil administration & dosage, Humans, Liver Neoplasms mortality, Survival Rate, Colorectal Neoplasms pathology, Hepatectomy, Infusions, Intra-Arterial, Liver Neoplasms secondary, Liver Neoplasms therapy
- Abstract
Hepatectomy and intraarterial chemotherapy for liver metastasis from colorectal cancer have been performed in our department. Intraarterial infusion chemotherapy has also been performed for unresectable liver metastasis. One hundred twenty-seven cases of liver metastasis from colorectal cancer were studied. The cases were divided into groups according to radicability of the original colorectal cancer, whether or not hepatectomy was performed, and whether or not they received intraarterial chemotherapy. Group I is cur C of origin. Group II is cur A or B without hepatectomy. Group III is cur A or B with hepatectomy. Each group was divided into a group without intraarterial chemotherapy (A) and a group with it (B). IA 23 cases, IB 13 cases, IIA 14 cases, IIB 21 cases, IIIA 28 cases, and IIIB 28 cases. The survival rate of group III was better than that of group II. The survival rate of group II was better than that of group I. There was no significant difference in survival rates between IA and IB. The survival rate of group IIB was significantly better than that of group IIA. The survival rate of group IIIB was significantly better than that of group III A. Hepatectomy and intraarterial chemotherapy after hepatectomy for liver metastasis from colorectal cancer were effective.
- Published
- 2002
29. [A case of hepatocellular carcinoma with portal tumor thrombus effectively treated by arterial infusion chemotherapy with low-dose cisplatin and 5-fluorouracil].
- Author
-
Nakazaki H, Takita W, Watanabe M, Hasebe Y, Tokura N, Seo A, Kurihara A, Takada M, Saito N, Shirasaka K, Kobayashi K, and Hirano K
- Subjects
- Aged, Cisplatin administration & dosage, Drug Administration Schedule, Female, Fluorouracil administration & dosage, Hepatic Artery, Humans, Infusions, Intra-Arterial, Antineoplastic Combined Chemotherapy Protocols administration & dosage, Carcinoma, Hepatocellular drug therapy, Liver Neoplasms drug therapy, Neoplastic Cells, Circulating drug effects, Portal System pathology
- Abstract
A 69-year-old female with unresectable hepatocellular carcinoma was treated with continuous arterial infusion of low-dose cisplatin (10 mg/body/day) and 5-fluorouracil (250 mg/body/day). The regimen was continued for 5 days then discontinued for 2 days, and repeated for 4 weeks. The portal tumor thrombus almost disappeared and HCC was smaller than before chemotherapy. Tumor marker (AFP and PIVKA-II) decreased remarkably. As tumor markers increased again 2 months later, the same regimen chemotherapy was performed once more. The patient was treated with arterial chemotherapy as an outpatient. The present case of hepatocellular carcinoma with portal tumor thrombus was effectively treated by arterial infusion chemotherapy with low dose cisplatin and 5-fluorouracil.
- Published
- 2002
30. [Percutaneous cryosurgery for liver tumors].
- Author
-
Nakazaki H, Watanabe M, Hasebe Y, Takita W, Ooshiro M, Seo A, Kurihara A, Kobayashi K, Teramoto T, and Hirano K
- Subjects
- Aged, Carcinoma, Hepatocellular secondary, Colonic Neoplasms pathology, Female, Humans, Liver Neoplasms secondary, Male, Middle Aged, Carcinoma, Hepatocellular surgery, Cryosurgery, Liver Neoplasms surgery
- Abstract
A new cryoprobe developed in our department makes it possible to perform percutaneous cryoablation for small liver tumors. This cryoprobe is placed into each lesion using an ultrasonic guidance technique. In this study there were 10 patients with hepatocellular carcinoma and 5 patients with liver metastases from colorectal carcinoma. In 6 cases the tumor size was below 2 cm, in 6 cases between 2 and 3 cm, and in 3 cases over 3 cm. Using a cryoprobe of 3 mm in diameter, each lesion was frozen using liquid nitrogen for 15 or 20 minutes then thawed for 10 minutes, and repeated. The ice ball was found to enlarge to 3 cm in 20 minutes and 5 cm in 60 minutes experimentally. Six cases were CR, 5 PR, 2 NC and 2 PD. After cryoablation, liver function did not change and there were no complications. However, as the size of the ice ball was small (about 3 cm), this method was insufficiently effective in some cases. Percutaneous cryoablation using this probe should be performed for tumors smaller than 3 cm.
- Published
- 2001
31. [Basic studies of intra-arterial hyperthermic treatment].
- Author
-
Maeda T, Kuramoto S, Shimojima Y, Takita W, Ohshiro M, Hanawa S, Watanabe M, Nakazaki H, Yoshio T, and Nonaka H
- Subjects
- Animals, Body Temperature, Doxorubicin pharmacokinetics, Female, Infusions, Intra-Arterial, Neoplasms, Experimental metabolism, Neoplasms, Experimental pathology, Rabbits, Saline Solution, Hypertonic administration & dosage, Doxorubicin administration & dosage, Hyperthermia, Induced, Neoplasms, Experimental therapy
- Abstract
Basic studies on intra-arterial hyperthermic treatment (1AHT) were conducted in rabbits implanted with VX2 tumor inside the thigh. For the purpose of determining the best temperature, saline added Adriamycin (ADM) (2 mg/body) that heated up to a predetermined objective temperature was injected. At 3 days after administration, the intratumor concentration of ADM (ITCA) and blood laboratory data were obtained. ITCA of the 53 degrees C group (1.13 +/- 0.41 micrograms/g) was significantly higher than those in the 23 degrees C group. In the 58 degrees C group, BUN, CPK, and creatinine were elevated. These data suggested that the best temperature of IAHT was about 53 degrees C. The treated rabbits were divided into 4 groups (heated saline added ADM, heated saline, non-heated saline added ADM, control) and the tumor growth rates after IAHT were investigated. The tumor size of the groups treated by heated saline was inhibited compared with that in the other two groups. There was no elevation of intratumor temperature in spite of IAHT. At 2 days after the IAHT, patho logically there were vacuolar degeneration in the arterial endothelial cells near the tumor, and narrowing of involved artery. These results suggest that the antitumor effect by IAHT is related with blood supply without hyperthermic effect.
- Published
- 1992
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.