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3. HTSeg: Hybrid Two-Stage Segmentation Framework for Intestine Segmentation from CT Volumes

Author

An, Qin, Oda, Hirohisa, Hayashi, Yuichiro, Kitasaka, Takayuki, Takimoto, Aitaro, Hinoki, Akinari, Uchida, Hiroo, Suzuki, Kojiro, Oda, Masahiro, Mori, Kesaku, Goos, Gerhard, Series Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Drechsler, Klaus, editor, Oyarzun Laura, Cristina, editor, Freiman, Moti, editor, Chen, Yufei, editor, Wesarg, Stefan, editor, and Erdt, Marius, editor

Published
2024
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4. M U-Net: Intestine Segmentation Using Multi-dimensional Features for Ileus Diagnosis Assistance

Author

An, Qin, Oda, Hirohisa, Hayashi, Yuichiro, Kitasaka, Takayuki, Hinoki, Akinari, Uchida, Hiroo, Suzuki, Kojiro, Takimoto, Aitaro, Oda, Masahiro, Mori, Kensaku, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Wu, Shandong, editor, Shabestari, Behrouz, editor, and Xing, Lei, editor

Published
2024
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8. Visualizing intestines for diagnostic assistance of ileus based on intestinal region segmentation from 3D CT images

Author

Oda, Hirohisa, Nishio, Kohei, Kitasaka, Takayuki, Amano, Hizuru, Takimoto, Aitaro, Uchida, Hiroo, Suzuki, Kojiro, Itoh, Hayato, Oda, Masahiro, and Mori, Kensaku

Subjects
Electrical Engineering and Systems Science - Image and Video Processing, Computer Science - Computer Vision and Pattern Recognition
Abstract

This paper presents a visualization method of intestine (the small and large intestines) regions and their stenosed parts caused by ileus from CT volumes. Since it is difficult for non-expert clinicians to find stenosed parts, the intestine and its stenosed parts should be visualized intuitively. Furthermore, the intestine regions of ileus cases are quite hard to be segmented. The proposed method segments intestine regions by 3D FCN (3D U-Net). Intestine regions are quite difficult to be segmented in ileus cases since the inside the intestine is filled with fluids. These fluids have similar intensities with intestinal wall on 3D CT volumes. We segment the intestine regions by using 3D U-Net trained by a weak annotation approach. Weak-annotation makes possible to train the 3D U-Net with small manually-traced label images of the intestine. This avoids us to prepare many annotation labels of the intestine that has long and winding shape. Each intestine segment is volume-rendered and colored based on the distance from its endpoint in volume rendering. Stenosed parts (disjoint points of an intestine segment) can be easily identified on such visualization. In the experiments, we showed that stenosed parts were intuitively visualized as endpoints of segmented regions, which are colored by red or blue.

Published
2020

26. Intestine Segmentation with Small Computational Cost for Diagnosis Assistance of Ileus and Intestinal Obstruction

Author

Oda, Hirohisa, Hayashi, Yuichiro, Kitasaka, Takayuki, Takimoto, Aitaro, Hinoki, Akinari, Uchida, Hiroo, Suzuki, Kojiro, Oda, Masahiro, Mori, Kensaku, Goos, Gerhard, Founding Editor, Hartmanis, Juris, Founding Editor, Bertino, Elisa, Editorial Board Member, Gao, Wen, Editorial Board Member, Steffen, Bernhard, Editorial Board Member, Woeginger, Gerhard, Editorial Board Member, Yung, Moti, Editorial Board Member, Oyarzun Laura, Cristina, editor, Cardoso, M. Jorge, editor, Rosen-Zvi, Michal, editor, Kaissis, Georgios, editor, Linguraru, Marius George, editor, Shekhar, Raj, editor, Wesarg, Stefan, editor, Erdt, Marius, editor, Drechsler, Klaus, editor, Chen, Yufei, editor, Albarqouni, Shadi, editor, Bakas, Spyridon, editor, Landman, Bennett, editor, Rieke, Nicola, editor, Roth, Holger, editor, Li, Xiaoxiao, editor, Xu, Daguang, editor, Gabrani, Maria, editor, Konukoglu, Ender, editor, Guindy, Michal, editor, Rueckert, Daniel, editor, Ziller, Alexander, editor, Usynin, Dmitrii, editor, and Passerat-Palmbach, Jonathan, editor

Published
2021
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37. Laparoscopic Fundoplication in Patients with Ventriculoperitoneal Shunts: A Systematic Review and Our Experience

Author

Kato, Daiki, primary, Uchida, Hiroo, additional, Tainaka, Takahisa, additional, Amano, Hizuru, additional, Ono, Yasuyuki, additional, Yasui, Akihiro, additional, Shirota, Chiyoe, additional, Sumida, Wataru, additional, Yokota, Kazuki, additional, Makita, Satoshi, additional, Takimoto, Aitaro, additional, Takada, Shunya, additional, Nakagawa, Yoichi, additional, Gohda, Yousuke, additional, Maeda, Takuya, additional, and Hinoki, Akinari, additional

Published
2024
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39. Safe thoracoscopic repair of recurrent congenital diaphragmatic hernia after initial open abdominal repair

Author

Gohda, Yousuke, primary, Yokota, Kazuki, additional, Uchida, Hiroo, additional, Shirota, Chiyoe, additional, Tainaka, Takahisa, additional, Sumida, Wataru, additional, Makita, Satoshi, additional, Takimoto, Aitaro, additional, Takada, Shunya, additional, Nakagawa, Yoichi, additional, Maeda, Takuya, additional, Guo, Yaohui, additional, and Hinoki, Akinari, additional

Published
2023
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40. Surgical Strategies for Neonates with Prenatally Diagnosed Congenital Biliary Dilatation

Author

Shirota, Chiyoe, primary, Hinoki, Akinari, additional, Tainaka, Takahisa, additional, Sumida, Wataru, additional, Makita, Satoshi, additional, Amano, Hizuru, additional, Takimoto, Aitaro, additional, Yasui, Akihiro, additional, Nakagawa, Yoichi, additional, Liu, Jiahui, additional, Guo, Yaohui, additional, Kato, Daiki, additional, Goda, Yousuke, additional, Maeda, Takuya, additional, and Uchida, Hiroo, additional

Published
2023
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42. Circumumbilical incision for neonatal abdominal surgery : additional skin incision when there is difficulty in manipulating the intestine

Author

Nakagawa, Yoichi, Hinoki, Akinari, Amano, Hizuru, Uchida, Hiroo, Shirota, Chiyoe, Tainaka, Takahisa, Sumida, Wataru, Yokota, Kazuki, Makita, Satoshi, Okamoto, Masamune, Takimoto, Aitaro, Yasui, Akihiro, Takada, Shunya, and Kato, Daiki

Subjects
intestinal atresia, meconium peritonitis, circumumbilical incision, neonates
Abstract

This study aimed to evaluate the safety and effectiveness of circumumbilical incision (CUI) for neonates requiring intestinal anastomosis. Seventy neonates requiring intestinal anastomosis at our institution between 2003 and 2020 were included in this retrospective case-control study. Patients were classified into the CUI (25 patients: 36%) and transverse incision (TI) groups (45 patients: 64%). Postoperative complications and surgical outcomes were compared between the two groups. Intestinal perforation at the non-anastomotic site occurred significantly more often in the CUI group than in the TI group (3 patients: 12%, and 0 patients: 0%, respectively (p = 0.042)). There were no between-group differences regarding anastomotic leakages, anastomotic strictures, time to enteral feeding, operative time, and blood loss. Neonatal intestinal surgery employing CUI might be associated with increased intestinal perforation at the non-anastomotic site. Hesitating to enlarge the skin incision to maintain favorable cosmetic outcomes might cause severe injury to the delicate neonatal intestine during the surgical procedure owing to the restricted surgical field. When performing CUI, we suggest that the skin incision should be extended without hesitation whenever there is difficulty in manipulating the intestine.

Published
2022

43. Case report: Laparoscopic gastrojejunostomy for duodenal atresia with situs inversus and preduodenal portal vein: a report of two cases

Author

Nakagawa, Yoichi, primary, Sumida, Wataru, additional, Makita, Satoshi, additional, Uchida, Hiroo, additional, Hinoki, Akinari, additional, Shirota, Chiyoe, additional, Tainaka, Takahisa, additional, Yokota, Kazuki, additional, Amano, Hizuru, additional, Yasui, Akihiro, additional, Takimoto, Aitaro, additional, Kato, Daiki, additional, Maeda, Takuya, additional, and Gohda, Yousuke, additional

Published
2023
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44. Case Report: Retropancreatic fascia hernia protruding into the thoracic cavity through a Bochdalek hernia

Author

Nakagawa, Yoichi, primary, Maeda, Takuya, additional, Uchida, Hiroo, additional, Takada, Shunya, additional, Hinoki, Akinari, additional, Shirota, Chiyoe, additional, Tainaka, Takahisa, additional, Sumida, Wataru, additional, Makita, Satoshi, additional, Amano, Hizuru, additional, Takimoto, Aitaro, additional, and Gohda, Yousuke, additional

Published
2023
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47. Patients with gastric volvulus recurrence have high incidence of wandering spleen requiring laparoscopic gastropexy and splenopexy

Author

Nakagawa, Yoichi, Uchida, Hiroo, Amano, Hizuru, Hinoki, Akinari, Tainaka, Takahisa, Shirota, Chiyoe, Sumida, Wataru, Yokota, Kazuki, Makita, Satoshi, Okamoto, Masamune, Takimoto, Aitaro, Yasui, Akihiro, Takada, Shunya, Kato, Daiki, Nakagawa, Yoichi, Uchida, Hiroo, Amano, Hizuru, Hinoki, Akinari, Tainaka, Takahisa, Shirota, Chiyoe, Sumida, Wataru, Yokota, Kazuki, Makita, Satoshi, Okamoto, Masamune, Takimoto, Aitaro, Yasui, Akihiro, Takada, Shunya, and Kato, Daiki

Abstract

Purpose: Though gastric volvulus in neonates and infants resolves by conservative therapy and aging, some cases require surgical intervention. This study aimed to review the cases of gastric volvulus requiring surgical intervention and evaluate their characteristics. Methods: We retrospectively reviewed gastric volvulus cases requiring surgical intervention. Surgical indication was persistent acute gastric volvulus and repeated hospitalization for gastric volvulus. We evaluated the characteristics of those cases requiring surgical intervention and the surgical results of laparoscopic gastropexy. Results: The median age of patients included was 4 years (range: 1–6 years). All eight cases of gastric volvulus requiring sugery had congenital spleen diseases. Six of the eight cases suffered from a wandering spleen, while two cases presented with situs inversus with asplenia. Both splenopexy (preperitoneal distension balloon [PDB] or blunt separaion methods) and gastropexy were performed in cases with wandering spleen. No postoperative complications were reported in any of the eight cases, except the recurrence of gastric volvulus due to suture shedding in one case. Conclusion: Laparoscopic gastropexy for gastric volvulus and splenopexy for cases concomitant with wandering spleen were found to be effective surgical approaches. Both PDB and blunt separation methods for making extraperitoneal pockets for the spleen were employed successfully.

Published
2023

48. Biochemical markers to predict the development of gastrointestinal bleeding and esophageal varices after portoenterostomy in biliary atresia

Author

Sumida, Wataru, Tainaka, Takahisa, Shirota, Chiyoe, Yokota, Kazuki, Makita, Satoshi, Okamoto, Masamune, Takimoto, Aitaro, Yasui, Akihiro, Takada, Shunya, Nakagawa, Yoichi, Kato, Daiki, Yokoyama, Shinya, Ishizu, Yoji, Amano, Hizuru, Guo, Yaohui, Hinoki, Akinari, Uchida, Hiroo, Sumida, Wataru, Tainaka, Takahisa, Shirota, Chiyoe, Yokota, Kazuki, Makita, Satoshi, Okamoto, Masamune, Takimoto, Aitaro, Yasui, Akihiro, Takada, Shunya, Nakagawa, Yoichi, Kato, Daiki, Yokoyama, Shinya, Ishizu, Yoji, Amano, Hizuru, Guo, Yaohui, Hinoki, Akinari, and Uchida, Hiroo

Abstract

Purpose: Gastrointestinal bleeding (GIB) due to esophageal varices (EV) is one of the factors that negatively impact native liver survival of patients with biliary atresia (BA). Gastrointestinal fibroscopy (GIF) is usually used to determine the presence of EVs; however, it requires general anesthesia. The aim of this study is to search for markers in blood tests obtained during routine check-ups that can predict the development of GIB. Methods: Data of patients with BA who underwent portoenterostomy at our hospital from 2014 to 2020 were retrospectively reviewed. The patients’ data were assigned to three groups according to specific time points: Group B, which included data at GIB; Group NB-T, which included data at GIF and EV treatment; and Group NB-NT, which included data at GIF without treatment. The data in Group B were compared to those of other groups. Results: In our study, GIB occurred in 11 patients, and 12 cases and 8 cases were classified into Groups NB-NT and NB-T, respectively. Compared with the other groups, only ChE and M2BPGi in Group B showed statistically significant differences. Conclusions: ChE and M2BPGi are useful for predicting GIB.

Published
2023

49. Laparoscopic revision of Kasai portoenterostomy after initial laparoscopic portoenterostomy in patients with biliary atresia: a limited but positive effect on native liver survival

Author

Kato, Daiki, Uchida, Hiroo, Amano, Hizuru, Hinoki, Akinari, Shirota, Chiyoe, Sumida, Wataru, Yokota, Kazuki, Makita, Satoshi, Okamoto, Masamune, Takimoto, Aitaro, Yasui, Akihiro, Takada, Shunya, Nakagawa, Yoichi, Kato, Daiki, Uchida, Hiroo, Amano, Hizuru, Hinoki, Akinari, Shirota, Chiyoe, Sumida, Wataru, Yokota, Kazuki, Makita, Satoshi, Okamoto, Masamune, Takimoto, Aitaro, Yasui, Akihiro, Takada, Shunya, and Nakagawa, Yoichi

Abstract

Purpose: It is important for patients with biliary atresia (BA) to retain the native liver after Kasai portoenterostomy (PE). Laparoscopic PE (Lap-PE) is standard, whereas laparoscopic revision of PE (Lap-revision) is performed as needed. We report the medium-term outcomes of Lap-revision. Methods: We retrospectively reviewed the demographics and outcomes of 63 patients who underwent Lap-PE between 2013 and 2021. Indications for revision included recurrent jaundice, repeat cholangitis, and persistent jaundice with temporary biliary excretion following the initial PE. We compared liver transplantation (LT) data of patients who underwent Lap-revision with those of patients who did not. Results: Lap-revision was performed in 20 patients. Of those 17 (excluding the two who were jaundice-free before the age of 1, and the one who underwent open conversion for bleeding), 11 (65%) were jaundice-free 1 year after Lap-revision. The surgical parameters of LT did not differ between patients who underwent Lap-revision and those who did not. Conclusion: Lap-revision for patients with BA had a limited but positive effect on native liver survival and did not adversely affect subsequent LT. Therefore, Lap-revision could be second-line standard therapy in patients with BA who have demonstrated biliary drainage at least once after initial PE.

Published
2023

50. The presence of high‐risk varices after sclerotherapy in biliary atresia

Author

Yokoyama, Shinya, Ishizu, Yoji, Honda, Takashi, Imai, Norihiro, Ito, Takanori, Yamamoto, Kenta, Shirota, Chiyoe, Tainaka, Takahisa, Sumida, Wataru, Makita, Satoshi, Takimoto, Aitaro, Nakagawa, Yoichi, Takada, Shunya, Ishigami, Masatoshi, Uchida, Hiroo, Kawashima, Hiroki, Yokoyama, Shinya, Ishizu, Yoji, Honda, Takashi, Imai, Norihiro, Ito, Takanori, Yamamoto, Kenta, Shirota, Chiyoe, Tainaka, Takahisa, Sumida, Wataru, Makita, Satoshi, Takimoto, Aitaro, Nakagawa, Yoichi, Takada, Shunya, Ishigami, Masatoshi, Uchida, Hiroo, and Kawashima, Hiroki

Abstract

Background: Esophagogastric varices (EGVs) may develop as a result of portal hypertension in children with biliary atresia (BA). Although endoscopic injection sclerotherapy (EIS) with ethanolamine oleate (EO) is reported useful for children, risk factors associated with the presence of high-risk EGVs after treatment remain unknown. Methods: The subjects were BA patients under 15 years of age who underwent EO-EIS. We retrospectively reviewed a total of 28 treatment sessions of EGVs with red signs and those larger than F2, which were considered to be at high risk of bleeding. Survival analysis was performed for the presence of high-risk EGVs at the time of follow-up endoscopy as the occurrence of an event. Results: Univariate analysis showed a significantly increased risk of the presence of high-risk EGVs post-EO-EIS in patients with increased liver stiffness (LS) and Mac-2 binding protein glycan isomer (M2BPGi), with hazard ratios of 1.48 and 1.15, respectively. The median presence-free period was significantly shorter in the LS ≥ 2.8 m/s patients than in those with LS <2.8 m/s (189 vs. 266 days). Similarly, the median presence-free period was significantly shorter in patients with M2BPGi ≥ 4.0 than in those with M2BPGi < 4.0 (182 vs. 203 days). The results of multivariate analysis revealed that the risk of the presence of high-risk EGVs was significantly higher only in the high-LS group, with a hazard ratio of 2.76. Conclusions: Increased LS is associated with risk of the presence of high-risk EGVs following EO-EIS in children with BA., First published: 21 December 2022

Published
2023

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