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8 results on '"Takashi Toshima"'

1. Laparoscopic cholecystectomy and common bile duct exploration for cholecystocholedocholithiasis with a left-sided gallbladder: Report of a case

Author

Akihiro Yasumoto, Hiromi Tokumura, Kenichi Takahashi, Yuji Funayama, Takashi Toshima, Hiroaki Musya, Mitsuo Yamasaki, Hiroyuki Sasaki, Naoki Matsumura, and Shoji Fukuyama

Subjects
medicine.medical_specialty, Diagnosis, Differential, Liver Function Tests, Humans, Medicine, Laparoscopic cholecystectomy, Aged, Ultrasonography, Common bile duct exploration, medicine.diagnostic_test, business.industry, Gallbladder, Cholecystolithiasis, General Medicine, Jaundice, Surgery, Radiography, Left-sided gallbladder, Choledocholithiasis, medicine.anatomical_structure, Cholecystectomy, Laparoscopic, Fundus (uterus), Abdominal ultrasonography, Vomiting, Female, medicine.symptom, business
Abstract

A 75-year old woman was admitted to our hospital with right upper quadrant pain, vomiting, and jaundice. Laboratory findings showed elevated total bilirubin, alkaline phosphatase, gamma-glutamyl transpeptidase, and C-reactive protein levels. Abdominal ultrasonography (US) and drip infusion cholangiographic computed tomography (DIC-CT) showed not only cholecystocholedocholithiasis, but a gallbladder located left of the round ligament and close to the lateral segments of the liver. We performed laparoscopic cholecystectomy (LC) with choledocholithotomy for suspected cholecystocholedocholithiasis with a left-sided gallbladder. Routine ports were inserted in the American configuration for LC. The gallbladder was normogradely separated from the gallbladder fossa, and the fundus of the gallbladder was lifted ventrally and toward to the patient's right shoulder. These procedures provided the usual view for laparoscopic choledochotomy. The patient recovered uneventfully and was discharged on postoperative day 10. To our knowledge, this is the first report of laparoscopic common bile exploration in a patient with a left-sided gallbladder.

Published
2009
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2. [A case with local recurrence of rectal cancer that responded to S-1 and PSK with long-term complete response]

Author

Ken-ichi, Takahashi, Tetsuya, Kakita, Yuji, Funayama, Hiromi, Tokumura, Takashi, Toshima, Shoji, Fukuyama, Hiroaki, Musya, Naoki, Matsumura, Hiroyuki, Sasaki, and Akihiro, Yasumoto

Subjects
Male, Antimetabolites, Antineoplastic, Antibiotics, Antineoplastic, Rectal Neoplasms, Adenocarcinoma, Mucinous, Drug Combinations, Oxonic Acid, Treatment Outcome, Antineoplastic Combined Chemotherapy Protocols, Humans, Proteoglycans, Neoplasm Recurrence, Local, Aged, Tegafur
Abstract

The patient was a 65-year-old male, who underwent low anterior resection for rectal cancer. The pathological diagnosis showed mucinous adenocarcinoma, pSS, and pN0. He complained of diarrhea and melena 4 months after the surgery. Abdominal computed tomography and colonofiberscopy showed a local recurrence of rectal cancer. Because the tumor was diagnosed as unresectable, combined chemotherapy of S-1 (100 mg/day, per os, 4 weeks of treatment and 2 weeks of rest) and PSK (3 g/day, per os, the same schedule as S-1) was started. After the 2 courses of chemotherapy, computed tomography and colonofiberscopy showed a complete disappearance of the tumor. The chemotherapy was continued until the 9th course and then stopped. Five years and 4 months since the induction of a complete response, the patient is still alive without disease recurrence. Combined chemotherapy of S-1 and PSK may be one of useful choices for recurrent colorectal cancer.

Published
2010

3. [A case of multiple metachronous metastases of colon cancer to the small intestine preoperatively diagnosed by double balloon enteroscopy and radically resected]

Author

Ken-ichi, Takahashi, Yuji, Funayama, Hiromi, Tokumura, Shigeru, Tanda, Hiroki, Maekawa, Takashi, Chiba, Takashi, Toshima, Shoji, Fukuyama, Hiroaki, Musha, Naoki, Matsumura, Hiroyuki, Sasaki, and Akihiro, Yasumoto

Subjects
Ileal Neoplasms, Jejunal Neoplasms, Colonic Neoplasms, Humans, Female, Endoscopy, Gastrointestinal, Aged, Catheterization
Abstract

The patient was a 75-year-old woman who had undergone resection of a transverse colon cancer two years before. She had anemia and intestinal obstruction, and a diagnosis of multiple metastases to the small intestine was made by double balloon enteroscopy. Eleven metastatic foci were resected by partial resection of the jejunum and ileum. Adjuvant FOLFOX chemotherapy was given, achieving a 26-month disease-free survival. The double balloon enteroscopy was useful in the definitive diagnosis of this case, and aggressive resection with adjuvant chemotherapy contributed to the good outcome.

Published
2010

5. Laparoscopic cholecystectomy and common bile duct exploration for cholecystocholedocholithiasis with a left-sided gallbladder: Report of a case.

Author

Naoki Matsumura, Hiromi Tokumura, Akihiro Yasumoto, Hiroyuki Sasaki, Mitsuo Yamasaki, Hiroaki Musya, Shoji Fukuyama, Kenichi Takahashi, Takashi Toshima, and Yuji Funayama

Subjects
CHOLECYSTECTOMY, LAPAROSCOPIC surgery, BILE duct diseases, CHOLANGIOGRAPHY, DIAGNOSTIC ultrasonic imaging, TOMOGRAPHY, HOSPITAL admission & discharge, THERAPEUTICS
Abstract

Abstract  A 75-year old woman was admitted to our hospital with right upper quadrant pain, vomiting, and jaundice. Laboratory findings showed elevated total bilirubin, alkaline phosphatase, γ-glutamyl transpeptidase, and Creactive protein levels. Abdominal ultrasonography (US) and drip infusion cholangiographic computed tomography (DIC-CT) showed not only cholecystocholedocholithiasis, but a gallbladder located left of the round ligament and close to the lateral segments of the liver. We performed laparoscopic cholecystectomy (LC) with choledocholithotomy for suspected cholecystocholedocholithiasis with a left-sided gallbladder. Routine ports were inserted in the American configuration for LC. The gallbladder was normogradely separated from the gallbladder fossa, and the fundus of the gallbladder was lifted ventrally and toward to the patient’s right shoulder. These procedures provided the usual view for laparoscopic choledochotomy. The patient recovered uneventfully and was discharged on postoperative day 10. To our knowledge, this is the first report of laparoscopic common bile exploration in a patient with a leftsided gallbladder. [ABSTRACT FROM AUTHOR]

Published
2009
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6. [Untitled]

Author

Takashi MATSUSHIRO, Tuneo HARIU, Hideyuki NAGASHIMA, Kyoji YAMAMOTO, Takashi TOSHIMA, Yoici IMAOKA, Rin YAMAGATA, Shinichi OKUYAMA, and Hitoshi MISHINA

Subjects
Gastroenterology, Surgery
Published
1983
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7. Proceedings of the 69th General Meeting from April 11–13, 1983-Osaka, Japan

Author

Yoshihiro Baba, Kunio Nagata, Yoshihisa Tsukada, Rintaro Narisawa, Akira Honma, Shinichi Hirose, Mineo Tomizawa, Toshihiko Ozaki, Fumihiro Ichida, Kenji Tanehiro, Nobuyoshi Kuno, Kumiko Kurimoto, Tetsuo Yokota, Tomoyuki Kano, Tatsuzo Kasugai, Kazuya Ueno, Katsuhide Shimakura, Akira Kakita, Masaaki Kambayashi, Tsuyoshi Takahashi, Eisei Sasaki, Yoichi Kasai, Toshihisa Takahashi, S. Shimaguchi, J. Ariyama, Masatoshi Sumida, Yukihiro Tsuchiya, Masao Ohto, Fumio Asagami, Tadasu Fuji, Norimasa Okabe, Kenji Sakurai, Shuichi Miyakawa, Yuji Horiguchi, Hiroshi Nakano, Yuji Nimura, N. Hayakawa, H. Hasegawa, J. Kamiya, S. Maeda, Y. Iyomasa, Yoshiro Matsumoto, Katsuhiko Sugahara, T. Ida, R. Mashimo, Shu Kou Wen, H. Fujii, S. Wakashiro, G. Isowa, S. Itoh, T. Yamakawa, Hidenori Udaka, Hideyuki Miyamoto, Toshikazu Tamura, Tsutomu Hirai, Osamu Okamura, Nobuhiko Komi, Nobuo Yoshioka, Yoshio Kawamura, Takahiko Kojima, Hitoshi Hachiya, Nobuyoshi Okumura, Kunihiko Suzuki, Toshiyuki Suzuki, Sadasuke Suzuki, Norishige Ozeki, Kazuo Goto, Shigehiro Shiraki, Toshihiko Takeuchi, Atsumasa Yamaguchi, Tadashi Shibue, Yukimitsu Kawaura, Takashi Iwa, Isao Takeda, Satoshi Nakano, Tomoko Kobayashi, Hideo Harada, Tokio Wakabayashi, Norio Sawabu, Yasuo Naito, Saburo Nakazawa, Tomoaki Isawa, Ikuo Tabata, Yuichi Sasaki, Hideaki Yamada, Shunichi Tatsumi, Kenzo Kobayashi, Eitaro Suzuki, Eizo Okamoto, Masakatsu Matsukawa, Toshio Nakanishi, Hiroiku Kawakami, Sotaro Fujimoto, Masatsugu Nakajima, Junichi Sugihara, Yoichi Saitoh, Takashi Matsushiro, Hideyuki Nagashima, Kyoji Yamamoto, Ryuji Nakamura, Junichi Tanaka, Fumito Shimizu, Takashi Toshima, Tuneo Hariu, Takukazu Nagakawa, Noriyoshi Suzuki, Wataru Takahashi, Ikunoshin Uematsu, Toshio Sato, K. Egami, T. Tajiri, N. Aoki, K. Yamaguchi, H. Yamakawa, A. Watanabe, M. Yano, S. Hatta, M. Yoshioka, M. Miki, A. Shirota, Koji Morimoto, Masato Furukawa, Toshinori Nakata, Ryuhei Yamada, Shinichiro Ito, Shigeru Maeda, Toshinori Morinaga, Makota Tanigawa, Toshiyuki Fujio, Hiroshi Inui, Hiroaki Kinoshita, Osamu Yamasaki, Eiichi Nagata, Kazuhiro Hirohashi, null Sakai, Tadahiro Takada, Hideki Yasuda, Makoto Shishikura, Katsuhiro Uchiyama, Yoshifumi Ogura, Ryuji Mizumoto, Kazuomi Nakazawa, Shunichi Sato, Isamu Kaito, Hiroshi Suzuki, Masao Ohtsuki, Yoshio Goto, M. Nomoto, K. Yunoue, K. Soga, F. Ichida, Y. Koike, K. Kiyosawa, Y. Akahane, K. Kamijyo, Y. Suzuki, S. Yamamura, T. Komatsu, A. Nagata, S. Furuta, Shigeki Hayashi, Yasuhiko Ohta, Kenji Fujiwara, Yuzuru Sato, Itsuro Ogata, Katsuyoshi Takatsuki, Shunji Mishiro, Hiroshi Oka, Masaru Furube, Nobuo Yamada, Hisao Shibata, Akitaka Shibuya, Eishi Hijikata, Shigenobu Kokubu, Kohdo Ishii, Haruya Okabe, Kenichi Sasaki, Akira Takada, Jugoro Takeuchi, Yasuyuki Ohta, Tadashi Tsujii, Fumiaki Ikegame, Masashi Unoura, Akihiko Furusawa, Nobuyoshi Tanaka, Yasuhiro Kato, Kenichi Kobayashi, Nobu Hattori, Yukihiko Tameda, Satoshi Kakiuchi, Yoshitane Kosaka, Shigeyoshi Harihara, Sukeo Yamamoto, Gotaro Yamada, Hideo Nagashima, Morikazu Onji, Yoshimasa Yamashita, Norio Horiike, Hirohiko Abe, Kazuhiko Hino, Masaru Kojima, Kazunori Noguchi, Hiromu Ueda, Tomoki Aritaka, Naoto Maruyama, Hitoshi Motoori, Kazuaki Yamauchi, Hiroshi Setoyama, Michio Sata, Yasuhiko Kubo, Kyuichi Tanikawa, Tatsuo Munehisa, Keisuke Nakata, Kenzo Kono, Toyoichi Muro, Akira Sato, Ryuji Furukawa, Nobuko Ishii, Yukio Kusumoto, Toshihiko Koji, Shigenobu Nagataki, Norio Nakao, Kohi Miura, Y. Sato, Y. Ohta, I. Ogata, S. Hayashi, K. Fujiwara, H. Oka, S. Furui, M. Iio, Kenji Ikeda, Eiji Oyake, Kazuo Takeuchi, Hiromitsu Kumada, Masao Nakajima, Akira Yoshiba, Masahiro Irimoto, Toshio Kobayashi, Morio Satoh, Ryusaku Yamada, Haruki Nakatsuka, Kenji Hirai, Masanobu Kumagai, Genjiro Yamaguchi, Masatoshi Tanaka, Masanobu Abe, Keijiro Ando, Yasushi Shingai, Kiwamu Okita, Tadayoshi Takemoto, Kazuo Tarao, Kenichiro Iwamura, Kenji Soga, Minoru Nomoto, Hitoshi Takagi, Takafumi Ichida, Shunsaku Higashi, Takashi Noguchi, Takashi Kanematsu, Kenji Takenaka, Takashi Matsumata, Takashi Sonoda, Toshiya Furuta, Keizo Sugimachi, Kiyoshi Inokuchi, Susumu Yamasaki, Hiroshi Hasegawa, Masatoshi Makuuchi, Yoshimi Nakanishi, Hidekazu Sano, Tetsuro Konno, Fumio Sano, Toshiharu Tsuzuki, Shuhei Iida, Naoki Yamanaka, Keiji Kuwata, Akihiro Toyosaka, Nobutaka Tanaka, Shiro Fujiwara, Hajime Yamazaki, Katsuji Sakai, Tokio Ono, Hiroaki Yamada, Masahiro Tada, Hitoshi Asakura, Kensuke Kobayashi, Tetsuo Morishita, Masaharu Tsuchiya, Nobutaka Sato, Hideo Hiratsuka, N. Ueda, and K. Harada

Subjects
medicine.medical_specialty, business.industry, Internal medicine, Gastroenterology, Library science, Medicine, business
Published
1984
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8. Effects of pH on the deconjugation of conjugated bilirubin in human bile

Author

Wataru Takahashi, Noriyoshi Suzuki, Takashi Toshima, and Fumiaki Shinya

Subjects
Chemical Phenomena, Bilirubin, Human bile, Conjugated bilirubin, Gallbladder Diseases, In Vitro Techniques, General Biochemistry, Genetics and Molecular Biology, Hydrolysis, chemistry.chemical_compound, Escherichia coli, Bile, Humans, Bile Pigments, Incubation, Glucuronidase, chemistry.chemical_classification, Chemistry, Dibekacin, General Medicine, Hydrogen-Ion Concentration, Unconjugated bilirubin, Enzyme, Biochemistry, Calcium bilirubinate
Abstract

SHINYA, F., TOSHIMA, T., TAKAHASHI, W. and SUZUKI, N. Effects of pH on the Deconjugation of Conjugated Bilirubin in Human Bile. Tohoku J. exp. Med., 1985, 147 -(3), 281-293 - The enzymatic activity of bacterial β-glucuronidase plays an essential role in the formation of calcium bilirubinate in bile. There are, however, many unsettled problems such as methodology of the assay for its enzymatic activity. In the present study (1) the azopigments from mono-conjugated bilirubin (MCB) and unconjugated bilirubin (UCB) in native bile were semiquantitatively determined, (2) the deconjugation of conjugated bilirubin (CB) in bile was estimated with azopigment analysis and (3) factors affecting the deconjugation of CB in bile, especially for pH value, were investigated. CB in bile was stable at physiologic pH during 6-hr incubation at 37°C, but was hydrolyzed at alkaline pH. At physiologic pH, addition of β-glucuronidase from E. coli hydrolyzed CB in bile and increased MCB and UCB in bile. Based upon the results mentioned above, it is suggested that alkaline pH and enzymatic activity of β-glucuronidase should cause the increase of UCB in bile. It can be said that β-glucuronidase is essential for the formation of calcium bilirubinate gallstone at physiologic pH.

Published
1985

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