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There is a growing trend of applying machine learning methods to medical datasets in order to predict patients' future status. Although some of these methods achieve high performance, challenges still exist in comparing and evaluating different models through their interpretable information. Such analytics can help clinicians improve evidence-based medical decision making. In this work, we develop a visual analytics system that compares multiple models' prediction criteria and evaluates their consistency. With our system, users can generate knowledge on different models' inner criteria and how confidently we can rely on each model's prediction for a certain patient. Through a case study of a publicly available clinical dataset, we demonstrate the effectiveness of our visual analytics system to assist clinicians and researchers in comparing and quantitatively evaluating different machine learning methods., This is the author's version of the article that has been accepted to PacificVis 2020 Visualization Meets AI Workshop

Machine learning for data-driven diagnosis has been actively studied in medicine to provide better healthcare. Supporting analysis of a patient cohort similar to a patient under treatment is a key task for clinicians to make decisions with high confidence. However, such analysis is not straightforward due to the characteristics of medical records: high dimensionality, irregularity in time, and sparsity. To address this challenge, we introduce a method for similarity calculation of medical records. Our method employs event and sequence embeddings. While we use an autoencoder for the event embedding, we apply its variant with the self-attention mechanism for the sequence embedding. Moreover, in order to better handle the irregularity of data, we enhance the self-attention mechanism with consideration of different time intervals. We have developed a visual analytics system to support comparative studies of patient records. To make a comparison of sequences with different lengths easier, our system incorporates a sequence alignment method. Through its interactive interface, the user can quickly identify patients of interest and conveniently review both the temporal and multivariate aspects of the patient records. We demonstrate the effectiveness of our design and system with case studies using a real-world dataset from the neonatal intensive care unit of UC Davis., Comment: This is the author's version of the article that has been accepted in PacificVis 2020 Visualization Meets AI Workshop

Dimensionality reduction (DR) methods are commonly used for analyzing and visualizing multidimensional data. However, when data is a live streaming feed, conventional DR methods cannot be directly used because of their computational complexity and inability to preserve the projected data positions at previous time points. In addition, the problem becomes even more challenging when the dynamic data records have a varying number of dimensions as often found in real-world applications. This paper presents an incremental DR solution. We enhance an existing incremental PCA method in several ways to ensure its usability for visualizing streaming multidimensional data. First, we use geometric transformation and animation methods to help preserve a viewer's mental map when visualizing the incremental results. Second, to handle data dimension variants, we use an optimization method to estimate the projected data positions, and also convey the resulting uncertainty in the visualization. We demonstrate the effectiveness of our design with two case studies using real-world datasets., Comment: This is the author's version of the article that has been published in IEEE Transactions on Visualization and Computer Graphics. The final version of this record is available at: 10.1109/TVCG.2019.2934433

Analysis of large, high-dimensional, and heterogeneous datasets is challenging as no one technique is suitable for visualizing and clustering such data in order to make sense of the underlying information. For instance, heterogeneous logs detailing machine repair and maintenance in an organization often need to be analyzed to diagnose errors and identify abnormal patterns, formalize root-cause analyses, and plan preventive maintenance. Such real-world datasets are also beset by issues such as inconsistent and/or missing entries. To conduct an effective diagnosis, it is important to extract and understand patterns from the data with support from analytic algorithms (e.g., finding that certain kinds of machine complaints occur more in the summer) while involving the human-in-the-loop. To address these challenges, we adopt existing techniques for dimensionality reduction (DR) and clustering of numerical, categorical, and text data dimensions, and introduce a visual analytics approach that uses multiple coordinated views to connect DR + clustering results across each kind of the data dimension stated. To help analysts label the clusters, each clustering view is supplemented with techniques and visualizations that contrast a cluster of interest with the rest of the dataset. Our approach assists analysts to make sense of machine maintenance logs and their errors. Then the gained insights help them carry out preventive maintenance. We illustrate and evaluate our approach through use cases and expert studies respectively, and discuss generalization of the approach to other heterogeneous data.

Finding the similarities and differences between groups of datasets is a fundamental analysis task. For high-dimensional data, dimensionality reduction (DR) methods are often used to find the characteristics of each group. However, existing DR methods provide limited capability and flexibility for such comparative analysis as each method is designed only for a narrow analysis target, such as identifying factors that most differentiate groups. This paper presents an interactive DR framework where we integrate our new DR method, called ULCA (unified linear comparative analysis), with an interactive visual interface. ULCA unifies two DR schemes, discriminant analysis and contrastive learning, to support various comparative analysis tasks. To provide flexibility for comparative analysis, we develop an optimization algorithm that enables analysts to interactively refine ULCA results. Additionally, the interactive visualization interface facilitates interpretation and refinement of the ULCA results. We evaluate ULCA and the optimization algorithm to show their efficiency as well as present multiple case studies using real-world datasets to demonstrate the usefulness of this framework., Comment: This is the author's version of the article that has been published in IEEE Transactions on Visualization and Computer Graphics. The final version of this record is available at: 10.1109/TVCG.2021.3114807

Data-driven problem solving in many real-world applications involves analysis of time-dependent multivariate data, for which dimensionality reduction (DR) methods are often used to uncover the intrinsic structure and features of the data. However, DR is usually applied to a subset of data that is either single-time-point multivariate or univariate time-series, resulting in the need to manually examine and correlate the DR results out of different data subsets. When the number of dimensions is large either in terms of the number of time points or attributes, this manual task becomes too tedious and infeasible. In this paper, we present MulTiDR, a new DR framework that enables processing of time-dependent multivariate data as a whole to provide a comprehensive overview of the data. With the framework, we employ DR in two steps. When treating the instances, time points, and attributes of the data as a 3D array, the first DR step reduces the three axes of the array to two, and the second DR step visualizes the data in a lower-dimensional space. In addition, by coupling with a contrastive learning method and interactive visualizations, our framework enhances analysts' ability to interpret DR results. We demonstrate the effectiveness of our framework with four case studies using real-world datasets., Comment: This is the author's version of the article that has been published in IEEE Transactions on Visualization and Computer Graphics. The final version of this record is available at: 10.1109/TVCG.2020.3028889

A common network analysis task is comparison of two networks to identify unique characteristics in one network with respect to the other. For example, when comparing protein interaction networks derived from normal and cancer tissues, one essential task is to discover protein-protein interactions unique to cancer tissues. However, this task is challenging when the networks contain complex structural (and semantic) relations. To address this problem, we design ContraNA, a visual analytics framework leveraging both the power of machine learning for uncovering unique characteristics in networks and also the effectiveness of visualization for understanding such uniqueness. The basis of ContraNA is cNRL, which integrates two machine learning schemes, network representation learning (NRL) and contrastive learning (CL), to generate a low-dimensional embedding that reveals the uniqueness of one network when compared to another. ContraNA provides an interactive visualization interface to help analyze the uniqueness by relating embedding results and network structures as well as explaining the learned features by cNRL. We demonstrate the usefulness of ContraNA with two case studies using real-world datasets. We also evaluate through a controlled user study with 12 participants on network comparison tasks. The results show that participants were able to both effectively identify unique characteristics from complex networks and interpret the results obtained from cNRL., To appear in IEEE Conference on Visual Analytics Science and Technology (VAST) 2020

Understanding and tuning the performance of extreme-scale parallel computing systems demands a streaming approach due to the computational cost of applying offline algorithms to vast amounts of performance log data. Analyzing large streaming data is challenging because the rate of receiving data and limited time to comprehend data make it difficult for the analysts to sufficiently examine the data without missing important changes or patterns. To support streaming data analysis, we introduce a visual analytic framework comprising of three modules: data management, analysis, and interactive visualization. The data management module collects various computing and communication performance metrics from the monitored system using streaming data processing techniques and feeds the data to the other two modules. The analysis module automatically identifies important changes and patterns at the required latency. In particular, we introduce a set of online and progressive analysis methods for not only controlling the computational costs but also helping analysts better follow the critical aspects of the analysis results. Finally, the interactive visualization module provides the analysts with a coherent view of the changes and patterns in the continuously captured performance data. Through a multi-faceted case study on performance analysis of parallel discrete-event simulation, we demonstrate the effectiveness of our framework for identifying bottlenecks and locating outliers., Comment: This is the author's preprint version that will be published in Proceedings of IEEE Pacific Visualization Symposium, 2020

The discretized closed Friedmann-Lema\^itre-Robertson-Walker (FLRW) universe with positive cosmological constant is investigated by Regge calculus. According to the Collins-Williams formalism, a hyperspherical Cauchy surface is replaced with regular 4-polytopes. Numerical solutions to the Regge equations approximate well to the continuum solution during the era of small edge length. Unlike the expanding polyhedral universe in three dimensions, the 4-polytopal universes repeat expansions and contractions. To go beyond the approximation using regular 4-polytopes we introduce pseudo-regular 4-polytopes by averaging the dihedral angles of the tessellated regular 600-cell. The degree of precision of the tessellation is called the frequency. Regge equations for the pseudo-regular 4-polytope have simple and unique expressions for any frequency. In the infinite frequency limit, the pseudo-regular 4-polytope model approaches the continuum FLRW universe., Comment: 24 pages, 9 figures. arXiv admin note: text overlap with arXiv:1612.06536