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24 results on '"Takahashi, Ikufumi"'

4. sj-docx-1-car-10.1177_19476035231154510 – Supplemental material for Treadmill Exercise Suppresses Histological Progression of Disuse Atrophy in Articular Cartilage in Rat Knee Joints during Hindlimb Suspension

Author

Takahashi, Ikufumi, Matsuzaki, Taro, Kuroki, Hiroshi, and Hoso, Masahiro

Subjects
FOS: Clinical medicine, FOS: Biological sciences, 110323 Surgery, 110604 Sports Medicine, FOS: Health sciences, 69999 Biological Sciences not elsewhere classified, 110314 Orthopaedics
Abstract

Supplemental material, sj-docx-1-car-10.1177_19476035231154510 for Treadmill Exercise Suppresses Histological Progression of Disuse Atrophy in Articular Cartilage in Rat Knee Joints during Hindlimb Suspension by Ikufumi Takahashi, Taro Matsuzaki, Hiroshi Kuroki and Masahiro Hoso in CARTILAGE

Published
2023
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5. sj-docx-3-car-10.1177_19476035231154510 – Supplemental material for Treadmill Exercise Suppresses Histological Progression of Disuse Atrophy in Articular Cartilage in Rat Knee Joints during Hindlimb Suspension

Author

Takahashi, Ikufumi, Matsuzaki, Taro, Kuroki, Hiroshi, and Hoso, Masahiro

Subjects
FOS: Clinical medicine, FOS: Biological sciences, 110323 Surgery, 110604 Sports Medicine, FOS: Health sciences, 69999 Biological Sciences not elsewhere classified, 110314 Orthopaedics
Abstract

Supplemental material, sj-docx-3-car-10.1177_19476035231154510 for Treadmill Exercise Suppresses Histological Progression of Disuse Atrophy in Articular Cartilage in Rat Knee Joints during Hindlimb Suspension by Ikufumi Takahashi, Taro Matsuzaki, Hiroshi Kuroki and Masahiro Hoso in CARTILAGE

Published
2023
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6. sj-docx-4-car-10.1177_19476035231154510 – Supplemental material for Treadmill Exercise Suppresses Histological Progression of Disuse Atrophy in Articular Cartilage in Rat Knee Joints during Hindlimb Suspension

Author

Takahashi, Ikufumi, Matsuzaki, Taro, Kuroki, Hiroshi, and Hoso, Masahiro

Subjects
FOS: Clinical medicine, FOS: Biological sciences, 110323 Surgery, 110604 Sports Medicine, FOS: Health sciences, 69999 Biological Sciences not elsewhere classified, 110314 Orthopaedics
Abstract

Supplemental material, sj-docx-4-car-10.1177_19476035231154510 for Treadmill Exercise Suppresses Histological Progression of Disuse Atrophy in Articular Cartilage in Rat Knee Joints during Hindlimb Suspension by Ikufumi Takahashi, Taro Matsuzaki, Hiroshi Kuroki and Masahiro Hoso in CARTILAGE

Published
2023
Full Text
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7. sj-docx-2-car-10.1177_19476035231154510 – Supplemental material for Treadmill Exercise Suppresses Histological Progression of Disuse Atrophy in Articular Cartilage in Rat Knee Joints during Hindlimb Suspension

Author

Takahashi, Ikufumi, Matsuzaki, Taro, Kuroki, Hiroshi, and Hoso, Masahiro

Subjects
FOS: Clinical medicine, FOS: Biological sciences, 110323 Surgery, 110604 Sports Medicine, FOS: Health sciences, 69999 Biological Sciences not elsewhere classified, 110314 Orthopaedics
Abstract

Supplemental material, sj-docx-2-car-10.1177_19476035231154510 for Treadmill Exercise Suppresses Histological Progression of Disuse Atrophy in Articular Cartilage in Rat Knee Joints during Hindlimb Suspension by Ikufumi Takahashi, Taro Matsuzaki, Hiroshi Kuroki and Masahiro Hoso in CARTILAGE

Published
2023
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13. Disuse Atrophy of Articular Cartilage Induced by Unloading Condition Accelerates Histological Progression of Osteoarthritis in a Post-traumatic Rat Model

Author

Takahashi, Ikufumi, Matsuzaki, Taro, Kuroki, Hiroshi, and Hoso, Masahiro

Abstract

Objective The study aim was to evaluate the histological relationship between osteoarthritis (OA) and articular cartilage in disuse atrophy induced by hindlimb unloading in a post-traumatic OA rat model.Design Forty male rats were divided into the 4 following experimental groups: control, hindlimb suspension (HS), OA induced by destabilization of the medial meniscus (OA), and OA induction after hindlimb suspension (HS-OA). Histological changes in the articular cartilage of the tibia were evaluated by the Osteoarthritis Research Society International (OARSI) scores and histomorphometrical analyses at 2, 4, and 8 weeks after OA induction.Results We confirmed that disuse atrophy of the articular cartilage was caused by thinning of the articular cartilage and the decrease in matrix staining for the nonloading period of 4 weeks. The OARSI scores and histomorphological analyses revealed that OA progressed significantly wider and deeper in the HS-OA group than in the OA group over time. In the sham group, disuse atrophy of the articular cartilage recovered at 2 weeks after reloading.Conclusions This study revealed that OA progressed faster in cartilage atrophy than in normal articular cartilage. Further studies are required for investigating the mechanisms of disuse atrophy of cartilage and its association with OA using the biochemical and immunohistochemical analysis.

Published
2021
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24. Age-related changes in rat joint capsule.

Author

Matsuzaki T, Takahashi I, and Hoso M

Abstract

[Purpose] We investigated morphological and histopathological changes in the joint capsule of rats with aging. [Materials and Methods] A total of 18 male Wistar rats were categorized into two groups: the control group (n=8), and the aged group (n=10). The aged group was reared until 75 weeks of age, while the control group was maintained until 11 weeks of age. At the end of the experiment period, the knee joints were sampled, joint capsules were subjected to histopathological analysis, and their thickness was measured. [Results] The joint capsule in the aging group exhibited significantly greater thickness compared to the control group. Histopathological examination revealed distinct differences between the two groups. The control group displayed gaps between the collagen fibers in the posterior joint capsule, along with loosely overlapping connective tissue and the presence of fat cells. Conversely, in the aged group's joint capsule, these gaps between the collagen fibers almost disappeared and fibers became densely packed and thickened. [Conclusion] These results were similar to our previous study in rats with immobilized hindlimb knee joints. Similar findings, including collagen fiber thickening, densification in the joint capsule, and reduced hindlimb knee joint range of motion, were consistent with those observed in the present investigation., Competing Interests: There are no conflicts of interest to declare. The authors are solely responsible for the content of the paper., (2023©by the Society of Physical Therapy Science. Published by IPEC Inc.)

Published
2023
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