Search

Your search keyword '"Tackenberg, B."' showing total 243 results
Start Over Author "Tackenberg, B."
243 results on '"Tackenberg, B."'

1. Efficacy and Safety of Masitinib in Progressive Forms of Multiple Sclerosis: A Randomized, Phase 3, Clinical Trial

Author

Vermersch, Patrick, Brieva-Ruiz, Luis, Fox, Robert J., Paul, Friedemann, Ramio-Torrenta, Lluis, Schwab, Matthias, Moussy, Alain, Mansfield, Colin, Hermine, Olivier, Maciejowski, Maciej, Hecham, N., Deri, N. Haydeé, Djelilovic-Vranic, J., Milanov, I., Shotekov, P., Blevins, G., Girard, J., Lapierre, Y., Camu, W., Castelnovo, G., Clavelou, P., Hautecoeur, P., Marziniak, M., Mayer, C., Oschmann, P., Reifschneider, G., Schoell, I., Tackenberg, B., Bergh, F. Then, Fakas, N., Grigoriadis, N., Kalochristianakis, D., Mitsikostas, D., Orologas, A., Tavernarakis, A., Thomaidis, T., Kovacs, K., Matyas, K., Piros, P., Satori, M., Anand, K., Shifrin, A., Banaszkiewicz, K., Bonek, R., Chahwan, M., Czernichowska - Kotiuszko, M., Darda-Ledzion, L., Debrowska - Wójcik, J., Dziki, M., Krzystanek, E., Kulka, M., Lisewski, P., Ratajczak, M., Szczudlik, A., Szczygiel, J., Tomaszewska, M., Wójcik, J., Zielonka, D., Chiru, M., Deme, S., Manescu, S., Nica, SM., Popescu, C., Szatmari, S., Fedyanin, A., Malkova, N., Popov, D., Volkova, L., Vorobeva, O., Brozman, M., Cimprichova, A., Cuchran, P., Gurcik, L., Krastev, G., Lisá, I., Nyeky, M., Poljaková, J., Turcani, P., Frost, A., Heckmann, J., Agüera, E., Coret, F., Escartin, A., Fernandez, V., Callizo, JR. Ara, Martin, G., Martinez-Rodriguez, JE., Gines, M. Martinez, Munoz, D., Olascoaga, J., Prieto, J., Ramo-Tello, C., Belal, S., Ben Ammou, S., Frih-Ayed, M., Gouider, R., Mhiri, C., Mrissa, R., Cherkez, A., Chmyr, H., Chudovska, L., Datskevych, S., Dziak, L., Galusha, A., Khavunka, M., Kobys, T., Kozyolkin, O., Lekomtseva, Y., Litovchenko, T., Moroz, O., Moskovko, G., Pashkovsky, V., Sanotskyi, Y., Shkrobot, S., Braley, T., Conway, J., Hughes, B., Katz, A., Rizvi, S., and Singer, R.

Published
2022
Full Text
View/download PDF

2. Apheresis therapies for NMOSD attacks: A retrospective study of 207 therapeutic interventions

Author

Kleiter, Ingo, Gahlen, Anna, Borisow, Nadja, Fischer, Katrin, Wernecke, Klaus-Dieter, Hellwig, Kerstin, Pache, Florence, Ruprecht, Klemens, Havla, Joachim, Kümpfel, Tania, Aktas, Orhan, Hartung, Hans-Peter, Ringelstein, Marius, Geis, Christian, Kleinschnitz, Christoph, Berthele, Achim, Hemmer, Bernhard, Angstwurm, Klemens, Stellmann, Jan-Patrick, Schuster, Simon, Stangel, Martin, Lauda, Florian, Tumani, Hayrettin, Mayer, Christoph, Krumbholz, Markus, Zeltner, Lena, Ziemann, Ulf, Linker, Ralf, Schwab, Matthias, Marziniak, Martin, Then Bergh, Florian, Hofstadt-van Oy, Ulrich, Neuhaus, Oliver, Zettl, Uwe K., Faiss, Jürgen, Wildemann, Brigitte, Paul, Friedemann, Jarius, Sven, Trebst, Corinna, Albrecht, P., Ayzenberg, I., Bayas, A., Bellmann-Strobl, J., Bischof, F., Bittner, S., Böttcher, T., Brettschneider, J., Buttmann, M., DSouza, M., Ettrich, B., Frank, B., Gass, A., Grothe, M., Guthke, K., Haarmann, A., Habedank, E., Hoffmann, F., Hoffmann, O., Hümmert, M.W., Junghans, J., Kaste, M., Kaulen, B., Kermer, P., Kern, P., Klotz, L., Köhler, W., Kolesilova, E., Korsen, M., Kowarik, M., Langel, S., Lee, D.H., Liebetrau, M., Luessi, F., Marouf, W., Meister, S., Melms, A., Metz, I., Münch, C., Niehaus, S., Pawlitzki, M., Pellkofer, H., Puhlmann, H.U., Pul, R., Retzlaf, N., Riedlinger, A., Rommer, P., Röpke, L., Rostásy, K., Rückriem, L., Ruschil, C., Schippling, S., Senel, M., Sieb, J.P., Sommer, C., Spreer, A., Steinbrecher, A., Stephanik, H., Stoppe, M., Süße, M., Tackenberg, B., Tünnerhoff, J., Veauthier, C., Walter, A., Wandinger, K.P., Warnke, C., Weber, M.S., Weissert, R., Wiendl, H., Wilke, C., Winkelmann, A., Yalachkov, Y., Young, K., Zentner, C., and Zipp, F.

Published
2018
Full Text
View/download PDF

4. Monitoring von Blutparametern unter verlaufsmodifizierender MS-Therapie: Substanzspezifische Relevanz und aktuelle Handlungsempfehlungen

Author

Klotz, L., Berthele, A., Brück, W., Chan, A., Flachenecker, P., Gold, R., Haghikia, A., Hellwig, K., Hemmer, B., Hohlfeld, R., Korn, T., Kümpfel, T., Lang, M., Limmroth, V., Linker, R. A., Meier, U., Meuth, S. G., Paul, F., Salmen, A., Stangel, M., Tackenberg, B., Tumani, H., Warnke, C., Weber, M. S., Ziemssen, T., Zipp, F., and Wiendl, H.

Published
2016
Full Text
View/download PDF

7. Aktuelles zur Therapieumstellung bei Multipler Sklerose

Author

Kolber, P., Luessi, F., Meuth, S.G., Klotz, L., Korn, T., Trebst, C., Tackenberg, B., Kieseier, B., Kümpfel, T., Fleischer, V., Tumani, H., Wildemann, B., Lang, M., Flachenecker, P., Meier, U., Brück, W., Limmroth, V., Haghikia, A., Hartung, H.-P., Stangel, M., Hohlfeld, R., Hemmer, B., Gold, R., Wiendl, H., and Zipp, F.

Published
2015
Full Text
View/download PDF

13. Efficacy and safety of IVIG in CIDP: Combined data of the PRIMA and PATH studies

Author

Merkies, ISJ, van Schaik, IN, Leger, J-M, Bril, V, van Geloven, N, Hartung, H-P, Lewis, RA, Sobue, G, Lawo, J-P, Durn, BL, Cornblath, DR, De Bleecker, JL, Sommer, C, Robberecht, W, Saarela, M, Kamienowski, J, Stelmasiak, Z, Tackenberg, B, Mielke, O, Sabet, A, George, K, Roberts, L, Carne, R, Blum, S, Henderson, R, Van Damme, P, Demeestere, J, Larue, S, D'Amour, C, Kunc, P, Valis, M, Sussova, J, Kalous, T, Talab, R, Bednar, M, Toomsoo, T, Rubanovits, I, Gross-Paju, K, Sorro, U, Auranen, M, Pouget, J, Attarian, S, Le Masson, G, Wielanek-Bachelet, A, Desnuelle, C, Delmont, E, Clavelou, P, Aufauvre, D, Schmidt, J, Zschuentzsch, J, Kramer, D, Hoffmann, O, Goerlitz, C, Haas, J, Chatzopoulos, M, Yoon, R, Gold, R, Berlit, P, Jaspert-Grehl, A, Liebetanz, D, Kutschenko, A, Stangel, M, Trebst, C, Baum, P, Bergh, F, Klehmet, J, Meisel, A, Klostermann, F, Oechtering, J, Lehmann, H, Schroeter, M, Hagenacker, T, Mueller, D, Sperfeld, A, Bethke, F, Drory, V, Algom, A, Yarnitsky, D, Murinson, B, Di Muzio, A, Ciccocioppo, F, Sorbi, S, Mata, S, Schenone, A, Grandis, M, Lauria, G, Cazzato, D, Antonini, G, Morino, S, Cocito, D, Zibetti, M, Yokota, T, Ohkubo, T, Kanda, T, Kawai, M, Kaida, K, Onoue, H, Kuwabara, S, Mori, M, Iijima, M, Ohyama, K, Baba, M, Tomiyama, M, Nishiyama, K, Akutsu, T, Yokoyama, K, Kanai, K, Eftimov, F, Notermans, NC, Visser, N, Faber, C, Hoeijmakers, J, Rejdak, K, Chyrchel-Paszkiewicz, U, Casanovas Pons, C, Antonia, M, Gamez, J, Salvado, M, Marquez Infante, C, Benitez, S, Lunn, M, Morrow, J, Gosal, D, Lavin, T, Melamed, I, Testori, A, Ajroud-Driss, S, Menichella, D, Simpson, Lai, EC-H, Dimachkie, M, Barohn, RJ, Beydoun, S, Johl, H, Lange, D, Shtilbans, A, Muley, S, Ladha, S, Freimer, M, Kissel, J, Latov, N, Chin, R, Ubogu, E, Mumfrey, S, Rao, T, MacDonald, P, Sharma, K, Gonzalez, G, Allen, J, Walk, D, Hobson-Webb, L, Gable, K, Franques, J, Morales, RJ, Nguento, A, Schrey, C, Zwolinska, G, Merkies, ISJ, van Schaik, IN, Leger, J-M, Bril, V, van Geloven, N, Hartung, H-P, Lewis, RA, Sobue, G, Lawo, J-P, Durn, BL, Cornblath, DR, De Bleecker, JL, Sommer, C, Robberecht, W, Saarela, M, Kamienowski, J, Stelmasiak, Z, Tackenberg, B, Mielke, O, Sabet, A, George, K, Roberts, L, Carne, R, Blum, S, Henderson, R, Van Damme, P, Demeestere, J, Larue, S, D'Amour, C, Kunc, P, Valis, M, Sussova, J, Kalous, T, Talab, R, Bednar, M, Toomsoo, T, Rubanovits, I, Gross-Paju, K, Sorro, U, Auranen, M, Pouget, J, Attarian, S, Le Masson, G, Wielanek-Bachelet, A, Desnuelle, C, Delmont, E, Clavelou, P, Aufauvre, D, Schmidt, J, Zschuentzsch, J, Kramer, D, Hoffmann, O, Goerlitz, C, Haas, J, Chatzopoulos, M, Yoon, R, Gold, R, Berlit, P, Jaspert-Grehl, A, Liebetanz, D, Kutschenko, A, Stangel, M, Trebst, C, Baum, P, Bergh, F, Klehmet, J, Meisel, A, Klostermann, F, Oechtering, J, Lehmann, H, Schroeter, M, Hagenacker, T, Mueller, D, Sperfeld, A, Bethke, F, Drory, V, Algom, A, Yarnitsky, D, Murinson, B, Di Muzio, A, Ciccocioppo, F, Sorbi, S, Mata, S, Schenone, A, Grandis, M, Lauria, G, Cazzato, D, Antonini, G, Morino, S, Cocito, D, Zibetti, M, Yokota, T, Ohkubo, T, Kanda, T, Kawai, M, Kaida, K, Onoue, H, Kuwabara, S, Mori, M, Iijima, M, Ohyama, K, Baba, M, Tomiyama, M, Nishiyama, K, Akutsu, T, Yokoyama, K, Kanai, K, Eftimov, F, Notermans, NC, Visser, N, Faber, C, Hoeijmakers, J, Rejdak, K, Chyrchel-Paszkiewicz, U, Casanovas Pons, C, Antonia, M, Gamez, J, Salvado, M, Marquez Infante, C, Benitez, S, Lunn, M, Morrow, J, Gosal, D, Lavin, T, Melamed, I, Testori, A, Ajroud-Driss, S, Menichella, D, Simpson, Lai, EC-H, Dimachkie, M, Barohn, RJ, Beydoun, S, Johl, H, Lange, D, Shtilbans, A, Muley, S, Ladha, S, Freimer, M, Kissel, J, Latov, N, Chin, R, Ubogu, E, Mumfrey, S, Rao, T, MacDonald, P, Sharma, K, Gonzalez, G, Allen, J, Walk, D, Hobson-Webb, L, Gable, K, Franques, J, Morales, RJ, Nguento, A, Schrey, C, and Zwolinska, G

Abstract

Intravenous immunoglobulin (IVIG) is a potential therapy for chronic inflammatory demyelinating polyneuropathy (CIDP). To investigate the efficacy and safety of the IVIG IgPro10 (Privigen) for treatment of CIDP, results from Privigen Impact on Mobility and Autonomy (PRIMA), a prospective, open-label, single-arm study of IVIG in immunoglobulin (Ig)-naïve or IVIG pre-treated subjects (NCT01184846, n = 28) and Polyneuropathy And Treatment with Hizentra (PATH), a double-blind, randomized study including an open-label, single-arm IVIG phase in IVIG pre-treated subjects (NCT01545076, IVIG restabilization phase n = 207) were analyzed separately and together (n = 235). Efficacy assessments included change in adjusted inflammatory neuropathy cause and treatment (INCAT) score, grip strength and Medical Research Council (MRC) sum score. Adverse drug reactions (ADRs) and ADRs/infusion were recorded. Adjusted INCAT response rate was 60.7% in all PRIMA subjects at Week 25 (76.9% in IVIG pre-treated subjects) and 72.9% in PATH. In the pooled cohort (n = 235), INCAT response rate was 71.5%; median time to INCAT improvement was 4.3 weeks. No clear demographic differences were noticed between early (responding before Week 7, n = 148) and late responders (n = 21). In the pooled cohort, median change from baseline to last observation was -1.0 (interquartile range -2.0; 0.0) point for INCAT score; +8.0 (0.0; 20.0) kPa for maximum grip strength; +3.0 (1.0; 7.0) points for MRC sum score. In the pooled cohort, 271 ADRs were reported in 105 subjects (44.7%), a rate of 0.144 ADRs per infusion. This analysis confirms the efficacy and safety of IgPro10, a recently FDA-approved IVIG for CIDP, in a population of mainly pre-treated subjects with CIDP [Correction added on 14 March 2019 after first online publication: the INCAT response rate has been corrected.].

Published
2019

14. IL-17(+) CD8(+) T cell suppression by dimethyl fumarate associates with clinical response in multiple sclerosis

Author

Luckel, C, Picard, F, Raifer, H, Campos Carrascosa, Lucia, Guralnik, A, Zhang, YJ, Klein, M, Bittner, S, Steffen, F, Moos, S, Marini, F, Gloury, R, Kurschus, FC, Chao, YY, Bertrams, W, Sexl, V, Schmeck, B, Bonetti, L, Grusdat, M, Lohoff, M, Zielinski, CE, Zipp, F, Kallies, A, Brenner, D, Berger, M, Bopp, T, Tackenberg, B, Huber, M, Luckel, C, Picard, F, Raifer, H, Campos Carrascosa, Lucia, Guralnik, A, Zhang, YJ, Klein, M, Bittner, S, Steffen, F, Moos, S, Marini, F, Gloury, R, Kurschus, FC, Chao, YY, Bertrams, W, Sexl, V, Schmeck, B, Bonetti, L, Grusdat, M, Lohoff, M, Zielinski, CE, Zipp, F, Kallies, A, Brenner, D, Berger, M, Bopp, T, Tackenberg, B, and Huber, M

Published
2019

15. Prospective multicenter validation of CSF protein biomarkers in patients with CIS and early MS

Author

Huss, A., Otto, M., Tackenberg, B., Stangel, M., Aktas, O., Meuth, S., Gross, C. C., Bayas, A., Wildemann, B., Luessi, F., Seipelt, M., Puetz, M., Antony, G., Weber, F., Uhr, M., Bischof', F., Ruprecht, K., Buck, D., Retzlaff, N., Zettl, U. K., Haghikia, A., Lukas, C., Hartung, H. -P., Bergh, F. Then, Warnke, C., Zipp, F., Wiendl, H., Hemmer, B., Gold, R., Tumani, H., Huss, A., Otto, M., Tackenberg, B., Stangel, M., Aktas, O., Meuth, S., Gross, C. C., Bayas, A., Wildemann, B., Luessi, F., Seipelt, M., Puetz, M., Antony, G., Weber, F., Uhr, M., Bischof', F., Ruprecht, K., Buck, D., Retzlaff, N., Zettl, U. K., Haghikia, A., Lukas, C., Hartung, H. -P., Bergh, F. Then, Warnke, C., Zipp, F., Wiendl, H., Hemmer, B., Gold, R., and Tumani, H.

Published
2018

16. Absence of Epstein-Barr virus seronegativity in a large cohort of patients with early multiple sclerosis

Author

Abrahamyan, S., Eberspaecher, B., Ambrosius, B., Hessler, N., Antony, G., Koenig, I. R., Hoshi, M. -M., Aly, L., Luessi, F., Groppa, S., Klotz, L., Meuth, S. G., Tackenberg, B., Stoppe, M., Bergh, F. Then, Tumani, H., Kuempfel, T., Stangel, M., Heesen, C., Wildemann, B., Paul, F., Bayas, A., Warnke, C., Weber, F., Linker, R. A., Ziemann, U., Zettl, U. K., Zipp, F., Wiendl, H., Hemmer, B., Gold, R., Salmen, A., Ruprecht, K., Abrahamyan, S., Eberspaecher, B., Ambrosius, B., Hessler, N., Antony, G., Koenig, I. R., Hoshi, M. -M., Aly, L., Luessi, F., Groppa, S., Klotz, L., Meuth, S. G., Tackenberg, B., Stoppe, M., Bergh, F. Then, Tumani, H., Kuempfel, T., Stangel, M., Heesen, C., Wildemann, B., Paul, F., Bayas, A., Warnke, C., Weber, F., Linker, R. A., Ziemann, U., Zettl, U. K., Zipp, F., Wiendl, H., Hemmer, B., Gold, R., Salmen, A., and Ruprecht, K.

Published
2018

17. Changes of disease characteristics and disease-modifying treatment within one year in the National German MS cohort

Author

Ambrosius, B., Hessler, N., Antony, G., Konig, I. R., Hoshi, M-M., Aly, L., Luessi, F., Groppa, S., Klotz, L., Meuth, S. G., Tackenberg, B., Stoppe, M., Bergh, F. Then, Tumani, H., Kuempfel, T., Stangel, M., Heesen, C., Wildemann, B., Paul, F., Bayas, A., Warnke, C., Weber, F., Linker, R. A., Ziemann, U., Zettl, U. K., Zipp, F., Wiendl, H., Hemmer, B., Gold, R., Salmen, A., Ambrosius, B., Hessler, N., Antony, G., Konig, I. R., Hoshi, M-M., Aly, L., Luessi, F., Groppa, S., Klotz, L., Meuth, S. G., Tackenberg, B., Stoppe, M., Bergh, F. Then, Tumani, H., Kuempfel, T., Stangel, M., Heesen, C., Wildemann, B., Paul, F., Bayas, A., Warnke, C., Weber, F., Linker, R. A., Ziemann, U., Zettl, U. K., Zipp, F., Wiendl, H., Hemmer, B., Gold, R., and Salmen, A.

Published
2018

18. Survey of diagnostic and treatment practices for multiple sclerosis (MS) in Europe. Part 2:Progressive MS, paediatric MS, pregnancy and general management

Author

Fernández, O., Delvecchio, M., Edan, G., Fredrikson, S., Giovannoni, G., Hartung, H. P., Havrdova, E., Kappos, L., Pozzilli, C., Soerensen, P. S., Tackenberg, B., Vermersch, P., Comi, G., Fernández, O., Delvecchio, M., Edan, G., Fredrikson, S., Giovannoni, G., Hartung, H. P., Havrdova, E., Kappos, L., Pozzilli, C., Soerensen, P. S., Tackenberg, B., Vermersch, P., and Comi, G.

Abstract

Background and purpose: The European Charcot Foundation supported the development of a set of surveys to understand current practice patterns for the diagnosis and management of multiple sclerosis (MS) in Europe. Part 2 of the report summarizes survey results related to secondary progressive MS (SPMS), primary progressive MS (PPMS), pregnancy, paediatric MS and overall patient management. Methods: A steering committee of MS neurologists developed case- and practice-based questions for two sequential surveys distributed to MS neurologists throughout Europe. Results: Respondents generally favoured changing rather than stopping disease-modifying treatment (DMT) in patients transitioning from relapsing−remitting MS to SPMS, particularly with active disease. Respondents would not initiate DMT in patients with typical PPMS symptoms, although the presence of ≥1 spinal cord or brain gadolinium-enhancing lesion might affect that decision. For patients considering pregnancy, respondents were equally divided on whether to stop treatment before or after conception. Respondents strongly favoured starting DMT in paediatric MS with active disease; recommended treatments included interferon, glatiramer acetate and, in John Cunningham virus negative patients, natalizumab. Additional results regarding practice-based questions and management are summarized. Conclusions: Results of part 2 of the survey of diagnostic and treatment practices for MS in Europe largely mirror results for part 1, with neurologists in general agreement about the treatment and management of SPMS, PPMS, pregnancy and paediatric MS as well as the general management of MS. However, there are also many areas of disagreement, indicating the need for evidence-based recommendations and/or guidelines.

Published
2018

19. Genetic predisposition in anti-LGI1 and anti-NMDA receptor encephalitis

Author

Mueller, Stefanie H, Färber, Anna, Sühs, Kurt-Wolfram, Lempert, Thomas, Winter, Benjamin, Schluh, Giesela, Gass, Achim, Hagenah, Ulrich, Hausler, Martin Georg, König, Schiffner, C., Tauber, Simone, Ayzenbeig, Ilya, Ringelstein, Marius, Ingo, Kleiter, Hellwig, Kerstin, Krogias, Christos, Heneka, Michael, Widmann, Guido, Witt, Juri-Alexander, Niehusmann, Pitt, Wagner, Jan, Schoch, Susanne, Becker, Albert, Kellinghaus, Christoph, Helmstaedter, Christoph, Elger, Christian, Kehrer, Stefanie, Langenfurth, Anika, Spruth, Eike, Priller, Josef, Paul, Friedemann, Harms, Lutz, Finke, Carsten, Wöpking, Sigrid, Bien, Christian G, Schneider, Auke, Seitz, Rüdiger, Goebels, Norbert, Aktas, Orhan, Huttner, Hagen, Gemer, Stefan, Staykov, Dimitre, van Elst, Ludger Tebartz, Endres, Dominique, Kraft, Andrea, Stich, Oliver, Rauer, Sebastian, Baumgartner, Annette, Neubauer, Bemd, Hofmann, Regina, Schirotzek, Ingo, Döppner, Thorsten, von Podewils, Felix, Süße, M., Dressel, Alexander, Zettl, Uwe K, Kaufmann, Max, Fleischer, Sabine, Heesen, Christoph, Stellmann, Jan-Patrick, Friese, Manuel, Ufer, Frederike, Trebst, Corinna, Stangel, Martin, Schönenberger, Silvia, Ehrlich, Sven, Wildemann, Brigitte, Jarius, Sven, Bösel, Julian, Roepke, Luise, Brämer, Dirk, Strubl, Julia, Kunze, Albrecht, Geis, Christian, Günther, Albrecht, Grote, Susann, Handreka, Robert, Maker, Michael, Dohmen, Christian, Stoppe, Muriel, Bergh, Florian Then, Ettrich, Barbara, Schilling, Ruth, Koertvelyessy, Peter, Bittner, Daniel, Spreer, Annette, Methner, Axel, Rostásy, Kevin, Pledl, Hans-Wemer, Hoyer, Carolin, Anlonso, Angelika, Szabo, Kristina, Held, Valentin, Tackenberg, B., Meuth, Sven, Philipp, Konstanze, Golombeck, Stefanie, Posevitz-Fejfar, Anita, Then Bergh, Florian, Wuerdemann, Till, Dik, Andre, Strippel, Christine, Möning, Constanze, Wiendl, Heinz, Melzer, Nico, Weissert, Robert, Fuchs, Komelius, Retzlaff, Nele, Schroeder, Herr, Prüss, Harald, Faiss, Jürgen H, Zettl, Uwe, Fousse, Mathias, Ragoschke-Schumm, Andreas, van Baalen, Andreas, Stumer, Klarissa, Berg, Daniela, Peuser, Anna, Nissen, Gunnar, Schmütz, Isa, Leypoldt, Frank, Lieb, Wolfgang, Bartsch, Thorsten, Falk, Kim Christin, Hummel, Katja, Moser, Andreas, Wandinger, Klaus Peter, Becker, Felicitas, Krumbholz, Markus, Bischof, Felix, Ihle, Jennifer, Dürr, Marc, Franke, Andre, Tumani, Hayrettin, Lewerenz, Jan, Doppler, Kathrin, Sommer, Claudia, Kuhlenbäumer, Gregor, Wandinger, Klaus-Peter, Encephalitis, German Network for Research on Autoimmune, Krämer, Markus, Lyss, Birgit, Schreiber, Stephan, Faiss, J., Wallenfelsova, Eva, Othman, Jalal, Sinnecker, Tim, Riedlinger, Arne, Fonseca, Patricia, Kern, Peter, Bogarin, Yuri, Hoffmann, Anna, Schwabe, Julia, Golombeck, Kristin S, Seidel, Gunter, Herwig, Antje, Rostasy, Kevin, Stolze, Henning, Körber, Rüdiger, Wiese, Lars, Schulze-Amberger, Jörg, Heide, Wolfgang, Geis, Tobias, Kümpfel, Tania, Blaes, Franz, Köhler, Wolfgang, Dogan, Muejgan, Bien, Christian, Kramme, Corinna, Grofß, Martin, Thomsen, Jens, Pulkowski, Ulrich, Hoepner, Robert, Thaler, Franziska, Schindler, Kaspar, Lippert, Julian, Marziniak, Martin, Ewering, Carina, Reimann, Gemot, Juranek, Aleksandra, Kanitz, Rolf-Dieter, Obrocki, Jost, Pfefferkorn, Thomas, Schimrigk, Sebastian, Elisak, Martin, Urbanek, Christian, Schön, Frauke, Schabet, Martin, Melville, Jutta, Finke, Alexander, Henningsen, Henning, Hansen, Hans-Christian, Küpper, Philipp, Berning, Sascha, Nagel, Michael, Hofstadt, Ulrich, Trendelenburg, George, Heider, Steffen, Linsa, Andreas, Muth, Carolin, Borggräfe, Ingo, Blaschek, Astrid, Laurent, Sarah, Havla, Joachim, Menge, Til, Bieniek, Rolf, Hoffmann, Frank, Philipsen, Alexandra, Gorsler, Anna, Pomschlegel, Sebastian, and Tesch, Manfred

Subjects
Adult, Male, Adolescent, genetics [Protein Serine-Threonine Kinases], Hashimoto Disease, Protein Serine-Threonine Kinases, LGI1 protein, human, genetics [Protein-Serine-Threonine Kinases], Polymorphism, Single Nucleotide, Receptors, N-Methyl-D-Aspartate, Young Adult, Doublecortin-Like Kinases, immunology [Receptors, N-Methyl-D-Aspartate], genetics [Hashimoto Disease], Humans, Genetic Predisposition to Disease, ddc:610, immunology [Encephalitis], genetics [Genetic Predisposition to Disease], Aged, Autoantibodies, metabolism [Hashimoto Disease], Intracellular Signaling Peptides and Proteins, Proteins, genetics [Encephalitis], DCLK2 protein, human, Middle Aged, Protein-Serine-Threonine Kinases, genetics [Proteins], immunology [Proteins], immunology [Hashimoto Disease], genetics [Polymorphism, Single Nucleotide], metabolism [Encephalitis], Encephalitis, metabolism [Autoantibodies], Female, Genome-Wide Association Study
Abstract

We performed a genome-wide association study in 1,194 controls and 150 patients with anti-N-methyl-D-aspartate receptor (anti-NMDAR, n = 96) or anti-leucine-rich glioma-inactivated1 (anti-LGI1, n = 54) autoimmune encephalitis. Anti-LGI1 encephalitis was highly associated with 27 single-nucleotide polymorphisms (SNPs) in the HLA-II region (leading SNP rs2858870 p = 1.22 × 10

Published
2017

20. Survey of diagnostic and treatment practices for multiple sclerosis (MS) in Europe. Part 2: Progressive MS, paediatric MS, pregnancy and general management

Author

Fernández, O., primary, Delvecchio, M., additional, Edan, G., additional, Fredrikson, S., additional, Giovannoni, G., additional, Hartung, H.-P., additional, Havrdova, E., additional, Kappos, L., additional, Pozzilli, C., additional, Soerensen, P. S., additional, Tackenberg, B., additional, Vermersch, P., additional, and Comi, G., additional

Published
2018
Full Text
View/download PDF

21. TRUST-Study: Methods of an Optional MRI-Safety Surveillance for Progressive Multifocal Leukoencephalopathy (PML) in Relapsing-Remitting Multiple Sclerosis Patients Treated with Natalizumab

Author

Gass, A., Wurfel, J., Kompan, I., Gregori, J., Ziemssen, T., Limmroth, V., Bayas, A., Haas, J., Linker, R., Maeurer, M., Stangel, M., Tackenberg, B., Meergans, M., Harlin, O., Hartung, H-P, Gass, A., Wurfel, J., Kompan, I., Gregori, J., Ziemssen, T., Limmroth, V., Bayas, A., Haas, J., Linker, R., Maeurer, M., Stangel, M., Tackenberg, B., Meergans, M., Harlin, O., and Hartung, H-P

Published
2017

23. Survey of diagnostic and treatment practices for multiple sclerosis in Europe

Author

Fernández, O, Delvecchio, M, Edan, G, Fredrikson, S, Gionvannoni, G, Hartung, H-P, Havrdova, E, Kappos, L, Pozzilli, C, Soerensen, P S, Tackenberg, B, Vermersch, P, Comi, G, Fernández, O, Delvecchio, M, Edan, G, Fredrikson, S, Gionvannoni, G, Hartung, H-P, Havrdova, E, Kappos, L, Pozzilli, C, Soerensen, P S, Tackenberg, B, Vermersch, P, and Comi, G

Abstract

BACKGROUND AND PURPOSE: Up-to-date information is needed on the extent to which neurologists treating multiple sclerosis (MS) in Europe are integrating rapidly evolving diagnostic criteria, disease-modifying therapies and recommendations for monitoring disease activity into their clinical practice.METHODS: A steering committee of MS neurologists used a modified Delphi process to develop case- and practice-based questions for two sequential surveys distributed to MS neurologists throughout Europe. Case-based questions were developed for radiologically isolated syndrome (RIS), clinically isolated syndrome (CIS), relapsing-remitting MS (RRMS) and RRMS with breakthrough disease.RESULTS: Multiple sclerosis neurologists from 11 European countries responded to survey 1 (n = 233) and survey 2 (n = 171). Respondents agreed that they would not treat the patients in the RIS or CIS cases but would treat a patient with a relatively mild form of RRMS. Choice of treatment was evenly distributed among first-line injectables and oral treatments for mild RRMS, and moved to second-line treatment as the RRMS case increased in severity. Additional results on RRMS with breakthrough disease are presented.CONCLUSIONS: Although there was general agreement on some aspects of treatment, responses to other management and clinical practice questions varied considerably. These results, which reflect current clinical practice patterns, highlight the need for additional MS treatment education and awareness and may help inform the development of MS practice guidelines in Europe.

Published
2017

25. Exome Array GWAS in 10,000 Germans Identifies Association between MUC22 and Multiple Sclerosis

Author

Dankowski, T., Buck, D., Andlauer, T. F., Antony, G., Bayas, A., Bechmann, Lars Peter, Berthele, A., Bettecken, T., Chan, A., Franke, A., Gold, R., Graetz, C., Haas, J., Hecker, M., Herms, S., Hohlfeld, R., Infante-Duarte, C., Jöckel, Karl-Heinz, Kieseier, B. C., Knier, B., Knop, M., Lichtner, P., Lieb, W., Lill, C. M., Limmroth, V., Linker, R. A., Loleit, V., Meuth, S., Moebus, Susanne, Mueller-Myhsok, B., Nischwitz, S., Noethen, M. M., Friedemann, P., Pütz, Martin, Ruck, T., Salmen, A., Stangel, M., Stellmann, J. -. P., Strauch, K., Stuerner, K. H., Tackenberg, B., Bergh, F. T. h. e. n., Tumani, H., Waldenberger, M., Weber, F., Wiend, H., Wildemann, B., Zettl, U. K., Ziemann, U., Zipp, F., Hemmer, B., and Ziegler, A.

Subjects
Medizin
Published
2015

38. NK cell peak after seizures

Author

Bauer, S, Cepok, S, Köller, M, Todorova-Rudolph, A, Nowak, M, Nockher, A, Lorenz, R, Tackenberg, B, Oertel, WH, Rosenow, F, Hemmer, B, and Hamer, HM

Published
2024
Full Text
View/download PDF

39. TRUST-Study: methods of an optional MRI-safety surveillance for progressive multifocal leukoencephalopathy (PML) in relapsing remitting multiple sclerosis patients treated with Natalizumab

Author

Gass, A., Wurfel, J., Kompan, I., Gregori, J., Ziemssen, T., Limmroth, V., Bayas, A., Haas, J., Linker, R., Maeurer, M., Stangel, M., Tackenberg, B., Meergans, M., Harlin, O., Hartung, H. -P., Gass, A., Wurfel, J., Kompan, I., Gregori, J., Ziemssen, T., Limmroth, V., Bayas, A., Haas, J., Linker, R., Maeurer, M., Stangel, M., Tackenberg, B., Meergans, M., Harlin, O., and Hartung, H. -P.

Published
2016

40. Ganzkörper-Vibrationstherapie bei Intensivpatienten

Author

Böselt, T, primary, Nell, C, additional, Kehr, K, additional, Holland, A, additional, Dresel, M, additional, Greulich, T, additional, Tackenberg, B, additional, Kenn, K, additional, Boeder, J, additional, Klapdor, B, additional, Kirschbaum, A, additional, Vogelmeier, C, additional, Alter, P, additional, and Koczulla, R, additional

Published
2016
Full Text
View/download PDF

43. TRUST study design-a study to evaluate an integrated approach for optimized patient management in multiple sclerosis patients treated with natalizumab

Author

Hartung, H-P, Ziemssen, T., Bayas, A., Tackenberg, B., Wuerfel, J., Limmroth, V., Linker, R., Maeurer, M., Haas, J., Stangel, M., Harlin, O., Winterstein, C., Meergans, M., Wernsdoerfer, C., Gass, A., Hartung, H-P, Ziemssen, T., Bayas, A., Tackenberg, B., Wuerfel, J., Limmroth, V., Linker, R., Maeurer, M., Haas, J., Stangel, M., Harlin, O., Winterstein, C., Meergans, M., Wernsdoerfer, C., and Gass, A.

Published
2014

46. Dimethylfumarat in der Therapie der schubförmigen MS

Author

Baum, K., primary, Boldt, H. J., primary, Chan, A., primary, Harms, L., primary, Hartung, H.-P., primary, Kieseier, B. C., primary, Korn, T., primary, Mäurer, M., primary, Meier, U., primary, Schreiber, H., primary, Tackenberg, B., primary, Wiendl, H., primary, Ziemssen, T., primary, and Gold, R., additional

Published
2014
Full Text
View/download PDF

47. IL-17A secretion by CD8(+) T cells supports Th17-mediated autoimmune encephalomyelitis

Author

Huber, Magdalena, Heink, Sylvia, Pagenstecher, Axel, Reinhard, Katharina, Ritter, Josephine, Visekruna, Alexander, Guralnik, Anna, Bollig, Nadine, Jeltsch, Katharina, Heinemann, Christina, Wittmann, Eva, Buch, Thorsten, Prazeres da Costa, Olivia, Bruestle, Anne, Brenner, Dirk, Mak, TW, Mittruecker, HW, Tackenberg, B, Kamradt, Thomas, Lohoff, Michael, Huber, Magdalena, Heink, Sylvia, Pagenstecher, Axel, Reinhard, Katharina, Ritter, Josephine, Visekruna, Alexander, Guralnik, Anna, Bollig, Nadine, Jeltsch, Katharina, Heinemann, Christina, Wittmann, Eva, Buch, Thorsten, Prazeres da Costa, Olivia, Bruestle, Anne, Brenner, Dirk, Mak, TW, Mittruecker, HW, Tackenberg, B, Kamradt, Thomas, and Lohoff, Michael

Published
2013

49. Neurofascin as a target for autoantibodies in peripheral neuropathies

Author

Ng, J. K. M., primary, Malotka, J., additional, Kawakami, N., additional, Derfuss, T., additional, Khademi, M., additional, Olsson, T., additional, Linington, C., additional, Odaka, M., additional, Tackenberg, B., additional, Pruss, H., additional, Schwab, J. M., additional, Harms, L., additional, Harms, H., additional, Sommer, C., additional, Rasband, M. N., additional, Eshed-Eisenbach, Y., additional, Peles, E., additional, Hohlfeld, R., additional, Yuki, N., additional, Dornmair, K., additional, and Meinl, E., additional

Published
2012
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results