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14 results on '"Tacchino, Roberto Maria"'

8. Effect of bariatric surgery on peripheral flow-mediated dilation and coronary microvascular function

Author

Nerla, Roberto, Tarzia, Pierpaolo, Sestito, Alfonso, Di Monaco, Antonio, Infusino, Fabio, Matera, Daniele, Greco, Francesco, Tacchino, Roberto Maria, Lanza, Gaetano Antonio, Crea, Filippo, Sestito, Alfonso (ORCID:0000-0001-9965-2997), Lanza, Gaetano Antonio (ORCID:0000-0003-2187-6653), Crea, Filippo (ORCID:0000-0001-9404-8846), Nerla, Roberto, Tarzia, Pierpaolo, Sestito, Alfonso, Di Monaco, Antonio, Infusino, Fabio, Matera, Daniele, Greco, Francesco, Tacchino, Roberto Maria, Lanza, Gaetano Antonio, Crea, Filippo, Sestito, Alfonso (ORCID:0000-0001-9965-2997), Lanza, Gaetano Antonio (ORCID:0000-0003-2187-6653), and Crea, Filippo (ORCID:0000-0001-9404-8846)

Abstract

BACKGROUND AND AIMS: To assess the effects of bariatric surgery (BS) on peripheral endothelial function and on coronary microvascular dilator function. METHODS AND RESULTS: We studied 50 morbidly obese patients (age 38 ± 9, 13 M) who underwent BS and 20 comparable obese controls (age 41 ± 11, 6 M) without any evidence of cardiovascular disease. Peripheral vascular dilator function was assessed by brachial artery diameter changes in response to post-ischemic forearm hyperaemia (flow-mediated dilation, FMD). Coronary microvascular function was assessed by measuring coronary blood flow (CBF) velocity response to i.v. adenosine and to cold pressor test (CPT) in the left anterior descending coronary artery by transthoracic Doppler echocardiography. The tests were performed at baseline and at 3-month follow-up. At baseline, FMD and CBF response to adenosine and CPT were similar in the 2 groups. Compared to baseline, FMD at follow-up improved significantly in BS patients (5.9 ± 2.7% to 8.8 ± 2.4%, p < 0.01), but not in controls (6.3 ± 3.2% vs. 6.4 ± 3.1%, p = 0.41). Similarly, a significant improvement of CBF response to adenosine (1.63 ± 0.47 to 2.45 ± 0.57, p < 0.01) and to CPT (1.43 ± 0.26 to 2.13 ± 0.55, p < 0.01) was observed in BS patients but not in controls (1.55 ± 0.38 vs. 1.53 ± 0.37, p = 0.85; and 1.37 ± 0.26 vs. 1.34 ± 0.21, p = 0.48, respectively). The favourable vascular effects of BS were similar independently of the presence and changes of other known cardiovascular risk factors and of basal values and changes of serum C-reactive protein levels. CONCLUSIONS: Our data show that, in morbidly obese patients, together with peripheral endothelial function, BS also improves coronary microvascular function. These effects suggest global improvement of vascular function which can contribute significantly to the reduction of cardiovascular risk by BS reported in previous studies.

Published
2012

9. Determinants of improvement in oxygenation consequent to reverse trendelenburg position in anesthetized morbidly obese patients

Author

Perilli, Valter, Sollazzi, Liliana, Modesti, Cristina, Sacco, Teresa, Bocci, Maria Grazia, Ciocchetti, P. P., Tacchino, Roberto Maria, Proietti, Rodolfo, Perilli, V. (ORCID:0000-0001-9655-4267), Sollazzi, L. (ORCID:0000-0002-2973-6236), Modesti, C. (ORCID:0000-0002-5858-3136), Sacco, T., Bocci, M. G., Tacchino, R. M., Proietti, R. (ORCID:0000-0003-1137-9928), Perilli, Valter, Sollazzi, Liliana, Modesti, Cristina, Sacco, Teresa, Bocci, Maria Grazia, Ciocchetti, P. P., Tacchino, Roberto Maria, Proietti, Rodolfo, Perilli, V. (ORCID:0000-0001-9655-4267), Sollazzi, L. (ORCID:0000-0002-2973-6236), Modesti, C. (ORCID:0000-0002-5858-3136), Sacco, T., Bocci, M. G., Tacchino, R. M., and Proietti, R. (ORCID:0000-0003-1137-9928)

Abstract

Determinants of improvement in oxygenation consequent to reverse Trendelenburg position in anesthetized morbidly obese patients.

Published
2004

10. Comparison of positive end-expiratory pressure with reverse Trendelenburg position in morbidly obese patients undergoing bariatric surgery: Effects on hemodynamics and pulmonary gas exchange

Author

Perilli, Valter, Sollazzi, Liliana, Modesti, Cristina, Annetta, Maria Giuseppina, Sacco, Teresa, Bocci, Maria Grazia, Tacchino, Roberto Maria, Proietti, Rodolfo, Perilli, V. (ORCID:0000-0001-9655-4267), Sollazzi, L. (ORCID:0000-0002-2973-6236), Modesti, C. (ORCID:0000-0002-5858-3136), Annetta, M. G. (ORCID:0000-0001-7574-1311), Sacco, T., Bocci, M. G., Tacchino, R. M., Proietti, R. (ORCID:0000-0003-1137-9928), Perilli, Valter, Sollazzi, Liliana, Modesti, Cristina, Annetta, Maria Giuseppina, Sacco, Teresa, Bocci, Maria Grazia, Tacchino, Roberto Maria, Proietti, Rodolfo, Perilli, V. (ORCID:0000-0001-9655-4267), Sollazzi, L. (ORCID:0000-0002-2973-6236), Modesti, C. (ORCID:0000-0002-5858-3136), Annetta, M. G. (ORCID:0000-0001-7574-1311), Sacco, T., Bocci, M. G., Tacchino, R. M., and Proietti, R. (ORCID:0000-0003-1137-9928)

Abstract

Background: Anesthetized morbidly obese patients often exhibit impaired pulmonary gas exchanges, mostly because of a reduction in functional residual capacity. At present, several approaches are suggested to ventilate these patients. Methods: The efficiency of positive end-expiratory pressure (PEEP) and reverse Trendelenburg position (RTP) were compared in order to improve oxygenation in 20 morbidly obese patients undergoing bariatric surgery. Results: Both PEEP and RTP determined a significant decrease in alveolar-arterial oxygen difference and an increase in total respiratory compliance (Ctot). RTP resulted in lower airway pressures than PEEP with similar improvements in Ctot and oxygenation. Concerning hemodynamic parameters, cardiac output (CO) significantly decreased with both PEEP and RTP. Conclusions: RTP and PEEP can be considered adequate ventilatory settings for morbidly obese patients, without any significant difference with regard to gas exchange improvement. However, the decrease in CO may partially counteract the beneficial effects on oxygenation of these ventilatory settings.

Published
2003

12. Lack of predictivity of serum neopterin, soluble interleukin-2 receptor, and serum amyloid A in long-term kidney transplant recipients

Author

Magalini, Sabina, Nanni, Giuseppe, Tacchino, Roberto Maria, Avolio, Alfonso Wolfango, Castagneto, Marco, Magalini, Sabina (ORCID:0000-0002-4056-1115), Nanni, Giuseppe (ORCID:0000-0001-9290-0695), Avolio, Alfonso Wolfango (ORCID:0000-0003-2491-7625), Magalini, Sabina, Nanni, Giuseppe, Tacchino, Roberto Maria, Avolio, Alfonso Wolfango, Castagneto, Marco, Magalini, Sabina (ORCID:0000-0002-4056-1115), Nanni, Giuseppe (ORCID:0000-0001-9290-0695), and Avolio, Alfonso Wolfango (ORCID:0000-0003-2491-7625)

Published
1992

13. Paradoxical effect of short-term protein loading on CsA-treated kidney transplant recipients

Author

Magalini, Sabina, Nanni, Giuseppe, Agnes, Salvatore, Serino, F, Avolio, Alfonso Wolfango, Tacchino, Roberto Maria, Castagneto, Marco, Magalini, Sabina (ORCID:0000-0002-4056-1115), Nanni, Giuseppe (ORCID:0000-0001-9290-0695), Agnes, Salvatore (ORCID:0000-0002-3341-4221), Avolio, Alfonso Wolfango (ORCID:0000-0003-2491-7625), Magalini, Sabina, Nanni, Giuseppe, Agnes, Salvatore, Serino, F, Avolio, Alfonso Wolfango, Tacchino, Roberto Maria, Castagneto, Marco, Magalini, Sabina (ORCID:0000-0002-4056-1115), Nanni, Giuseppe (ORCID:0000-0001-9290-0695), Agnes, Salvatore (ORCID:0000-0002-3341-4221), and Avolio, Alfonso Wolfango (ORCID:0000-0003-2491-7625)

Published
1989

14. Increase in N-acetyl-beta-glucosaminidase excretion as a marker of kidney damage in cyclosporine-treated renal allografts

Author

Avolio, Alfonso Wolfango, Nanni, Giuseppe, Citterio, Franco, Pozzetto, U, Magalini, Sabina, Zappacosta, Bruno, Tacchino, Roberto Maria, Zuppi, Cecilia, Castagneto, Marco, Avolio, Alfonso Wolfango (ORCID:0000-0003-2491-7625), Nanni, Giuseppe (ORCID:0000-0001-9290-0695), Citterio, Franco (ORCID:0000-0003-0489-6337), Magalini, Sabina (ORCID:0000-0002-4056-1115), Zuppi, Cecilia (ORCID:0000-0003-4710-4934), Avolio, Alfonso Wolfango, Nanni, Giuseppe, Citterio, Franco, Pozzetto, U, Magalini, Sabina, Zappacosta, Bruno, Tacchino, Roberto Maria, Zuppi, Cecilia, Castagneto, Marco, Avolio, Alfonso Wolfango (ORCID:0000-0003-2491-7625), Nanni, Giuseppe (ORCID:0000-0001-9290-0695), Citterio, Franco (ORCID:0000-0003-0489-6337), Magalini, Sabina (ORCID:0000-0002-4056-1115), and Zuppi, Cecilia (ORCID:0000-0003-4710-4934)

Published
1987

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