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Aim: Celiac disease is associated with an increased risk of cardiovascular disease due to inflammation and autoimmunity involved in its pathophysiology. We aimed to evaluate vascular involvement in children with celiac disease based on their augmentation index, carotid pulse wave velocity, carotid intima-media thickness, echocardiographic findings, and blood pressure. Materials and Methods: This cross-sectional and controlled study was performed at a single center between 2018 and 2019. The study population consisted of 44 patients with celiac disease who had been on a gluten-free diet for at least one year. Results: We compared celiac patients with a healthy group. While the celiac patients had significantly higher carotid intima media thickness and carotid pulse wave velocity values, there was no difference in the augmentation index values. There was no significant difference in carotid artery intimal medial thickness, augmentation index and carotid pulse wave velocity values between the diet-compliant and non-compliant groups. Conclusion: Although hypertension was not detected, arterial stiffness and carotid intima media thickness measurements were higher in the celiac disease patients compared to the healthy controls. This showed that these parameters can be used in early vascular damage assessment. These measurements, which are non-invasive and repeatable, can be a guide for the monitoring of the development of preclinical atherosclerosis in the follow-up of the pediatric patients diagnosed with celiac disease. [ABSTRACT FROM AUTHOR]

Aim: We aimed to evaluate quality of life in functional and organic dyspepsia and its change during follow-up. Materials and Methods: Children between 4-17 years of age with dyspeptic complaints were enrolled into this study. Organic and functional dyspepsia were differentiated based on clinical findings and the findings of upper gastrointestinal endoscopy, if performed. The Kinder Lebensqualität Fragebogen (KINDL) questionnaire was conducted when the patients were referred to hospital and at their 1st and 3rd month visits, prospectively. Both groups were compared with regard to their demographic data, symptoms and quality of life scores. Factors which affected the KINDL results and any changes in the KINDL scores during follow-up were evaluated. Results: The study group consisted of 71 functional dyspepsia and 65 organic dyspepsia patients. The mean quality of life scores in the physical wellness and school subscales were higher among the functional dyspepsia patients. The total score of the functional dyspepsia group was higher. There was no relation between the individual's gender, their number of symptoms and their KINDL scores. At the first month visit, the total scores and mean scores of the self-esteem, family, school and friends subscales were higher in the functional dyspepsia group. At the third month visit, the mean self-esteem score was higher in the functional dyspepsia group. Total scores increased significantly during follow-up in both the organic dyspepsia and functional dyspepsia groups. This increase was higher in the organic dyspepsia group. Conclusion: Quality of life in both functional dyspepsia and organic dyspepsia patients is affected; applying recommendations and treatment increased the quality of life of both groups. A quality of life scale can be used to monitor response to treatment. [ABSTRACT FROM AUTHOR]