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Your search keyword '"TUTAL GÜRSOY, GÖRKEM"' showing total 9 results
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9 results on '"TUTAL GÜRSOY, GÖRKEM"'

4. Evaluation of Cognitive Performance and Daily Life Activities in Dementia Patients with Online cognitive Tracking and Exercise Application

Author

ÖZ, DİDEM, ŞAHİNER, TÜRKER, ATES, MIRUNA FLORENTINA, KARALI, FENİSE SELİN, MENENGİÇ, KÜBRA NUR, SARI, TACİM, KUTLAR, HAMDİYE NİHAL, GENÇ, HAMİT, ÇELİK, ÇİĞDEM, MEHTİYEV, DUYGU, ŞİRİNOCAK, PINAR, ÜLKER, MUSTAFA, BİZPINAR, ÖZLEM, TUTAL GÜRSOY, GÖRKEM, AKKAYA, ÖMER FARUK, BÖLÜKBAŞI, OKAN, SUSUZ, ÇİĞDEM, İNCİ, İPEK, İŞERİ, PERVİN, SAKALLI, NAZAN, ÖZLER, ÖZGE GÖNÜL, YALÇIN ÇAKMAKLI, GÜL, TAŞKIRAN SAĞ, ASLIHAN, ÖZDAĞ KİRAZ, MÜMİNE, GÖÇMEN YILMAZ, GÜLCAN, ULUAKAY KANDEMİR, ARZU, KENANGİL, GÜLAY, CAN, UFUK, KİBAROĞLU, SEDA, GELİŞİN, ÖZLEM, ÖZBABALIK ADAPINAR, BELGİN DEMET, MUNGAN, BEHİYE, ACIMAN DEMİREL, ESRA, EVLİCE, AHMET TURAN, DOĞAN, HASAN, OKLUOĞLU ÖNAY, TUĞBA, YILMAZ KÜSBECİ, ÖZGE, ER, DİDEM, ÇULHA OKTAR, AYLA, SAKA TOPÇUOĞLU, ESEN, ÖZGE, AYNUR, ÇINAR, NİLGÜN, and BÜLBÜL, NAZLI GAMZE

Published
2022

6. Demans Hastalarında Günlük Yaşam Akti̇vi̇teleri̇ni̇n Çevri̇mi̇çi̇ Bi̇li̇şsel Taki̇p ve Egzersi̇z Uygulaması İle Değerlendi̇ri̇lmesi̇

Author

OKLUOĞLU ÖNAY, TUĞBA, İŞERİ, PERVİN, İNCİ, İPEK, SUSUZ, ÇİĞDEM, BÖLÜKBAŞI, OKAN, AKKAYA, ÖMER FARUK, TUTAL GÜRSOY, GÖRKEM, BİZPINAR, ÖZLEM, ÜLKER, MUSTAFA, ŞİRİNOCAK, PINAR, MEHTİYEV, DUYGU, ÇELİK, ÇİĞDEM, GENÇ, HAMİT, KUTLAR, HAMDİYE NİHAL, SARI, TACİM, MENENGİÇ, KÜBRA NUR, KARALI, FENİSE SELİN, ATES, MIRUNA FLORENTINA, ULUAKAY KANDEMİR, ARZU, TAŞKIRAN SAĞ, ASLIHAN, ÖZDAĞ KİRAZ, MÜMİNE, GÖÇMEN YILMAZ, GÜLCAN, ÖZ, DİDEM, BÜLBÜL, NAZLI GAMZE, ÇINAR, NİLGÜN, ÖZGE, AYNUR, SAKA TOPÇUOĞLU, ESEN, ÇULHA OKTAR, AYLA, ER, DİDEM, YILMAZ KÜSBECİ, ÖZGE, DOĞAN, HASAN, EVLİCE, AHMET TURAN, ACIMAN DEMİREL, ESRA, MUNGAN, BEHİYE, ÖZBABALIK ADAPINAR, BELGİN DEMET, GELİŞİN, ÖZLEM, ŞAHİNER, TÜRKER, KİBAROĞLU, SEDA, CAN, UFUK, KENANGİL, GÜLAY, SAKALLI, NAZAN, ÖZLER, ÖZGE GÖNÜL, and YALÇIN ÇAKMAKLI, GÜL

Published
2021

7. Demans Hastalarında Çevrimiçi Bilişsel Oyun Performansının SLUMS Skorları ile Karşılaştırılması

Author

ÖZBABALIK ADAPINAR, BELGİN DEMET, ŞAHİNER, TÜRKER, MENENGİÇ, KÜBRA NUR, KARALI, FENİSE SELİN, ATES, MIRUNA FLORENTINA, ÖZ, DİDEM, OKLUOĞLU ÖNAY, TUĞBA, ÇINAR, NİLGÜN, ÖZGE, AYNUR, SAKA TOPÇUOĞLU, ESEN, BÜLBÜL, NAZLI GAMZE, ÇULHA OKTAR, AYLA, ER, DİDEM, YILMAZ KÜSBECİ, ÖZGE, DOĞAN, HASAN, GÖÇMEN YILMAZ, GÜLCAN, ÖZDAĞ KİRAZ, MÜMİNE, TAŞKIRAN SAĞ, ASLIHAN, YALÇIN ÇAKMAKLI, GÜL, ÖZLER, ÖZGE GÖNÜL, SAKALLI, NAZAN, İŞERİ, PERVİN, İNCİ, İPEK, SUSUZ, ÇİĞDEM, BÖLÜKBAŞI, OKAN, TUTAL GÜRSOY, GÖRKEM, BİZPINAR, ÖZLEM, ÜLKER, MUSTAFA, ŞİRİNOCAK, PINAR, MEHTİYEV, DUYGU, ÇELİK, ÇİĞDEM, GENÇ, HAMİT, KUTLAR, HAMDİYE NİHAL, SARI, TACİM, EVLİCE, AHMET TURAN, ACIMAN DEMİREL, ESRA, MUNGAN, BEHİYE, GELİŞİN, ÖZLEM, KİBAROĞLU, SEDA, CAN, UFUK, KENANGİL, GÜLAY, and ULUAKAY KANDEMİR, ARZU

Published
2021

8. The relationship between temporal muscle thickness and triglyceride glucose index in sarcopenia with mortality and third-month functional outcomes in patients after acute stroke

Author

Tutal Gürsoy, Görkem, Görgülü, Ümit, Tengirşenk, Zeynep, and Bektas, Hesna

Abstract

Especially in recent years, temporal muscle thickness has been used as an important parameter for sarcopenia in neurological disorders. In addition, triglyceride glucose index was evaluated separately in studies conducted in terms of coronary diseases, diabetes, high blood pressure, body mass index and acute stroke. In this clinical study, unlike the others, both temporal muscle thickness and triglyceride glucose index were evaluated together in acute stroke patients in terms of sarcopenia. We aimed to investigate the relationship between temporal muscle thickness and triglyceride glucose index, which is atherosclerotic index, with mortality and 3rd month functional outcomes in acute stroke patients. In this retrospective study, 147 patients admitted to Ankara City Hospital with the diagnosis of acute ischemic stroke between January 2021 and September 2022 were evaluated. Fasting triglyceride glucose indexes of the patients were calculated. The temporal muscle thickness measurement of the patients was performed by the radiologist using computed tomography images. Those who scored 3 or higher on the modified Rankin Scale (mRS) at the third month were considered to have poor functional outcome. A significant cutoff point was found for estimating mortality for the temporal muscle thickness parameter [area under the curve for a receiver operating characteristic curve (AUC) = 0.636; P = .012]. The cutoff point was obtained as ≤ 5.2. Sensitivity value was 65%, specificity value was 65%, the positive predictive value (PPV) value was 42.62% and the negative predictive value (NPV) value was 82.28%. Similarly, for the triglyceride glucose index parameter, there was a significant cutoff point in estimating mortality (AUC = 0.673; P = .003). The cutoff point was obtained as ≥ 8.23. Sensitivity value was 91.18%, specificity value was 13%, PPV value was 26.96% and NPV value was 81%. Temporal muscle thickness and triglyceride glucose index parameters were found to be statistically important parameters of sarcopenia. It was concluded that the evaluation of these 2 parameters in terms of both mortality and sarcopenia in acute stroke patients is important in the evaluation of neurological and cardiac disorders.

Published
2023
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9. Resveratrol showed anti-inflammatory effects on hippocampus via suppressing NFκB.

Author

Aşır F, Aslanoğlu B, Tutal Gürsoy G, and Tuncer MC

Subjects
Animals, Rats, Male, Glutathione metabolism, Malondialdehyde metabolism, Resveratrol pharmacology, Hippocampus metabolism, Hippocampus drug effects, Hippocampus pathology, NF-kappa B metabolism, Anti-Inflammatory Agents pharmacology, Anti-Inflammatory Agents therapeutic use, Brain Injuries, Traumatic drug therapy, Brain Injuries, Traumatic metabolism, Brain Injuries, Traumatic pathology
Abstract

Background: Traumatic brain injury (TBI) is the damage to the brain caused by external blow or jolt to the head or body. TBI secondarily induces cell damage in the hippocampus. This study aimed to investigate effects of resveratrol treatment histological examination and nuclear factor kappa B (NFκB) expression in hippocampus after TBI., Materials and Methods: Twenty-four rats were assigned to three groups: sham, TBI and TBI + Resveratrol. TBI was conducted by dropping a 50 g weight from a 1-meter height from a tube to the head of animals. 20 mg/kg resveratrol was orally administered to rats after TBI. Blood was collected to measure malondialdehyde (MDA) and glutathione (GSH) contents. Cerebral tissues were processed for histopathology and furtherly for immunohistochemical analysis., Results: MDA content was significantly increased and GSH value were significantly decreased in TBI group compared to sham group. Resveratrol treatment significantly improved biochemical scores in TBI + Resveratrol group. Normal histological appearance was observed in hippocampal sections of sham group. In TBI group, neurons in hippocampus were degenerated. Their nuclei were pyknotic. Other neurons and supportive neuroglial cells in hippocampal proper and dentate gyrus were also disrupted. Hippocampal proper integrity was lost with vascular dilatation. NFκB was upregulated in hippocampal neurons of TBI group., Conclusions: Resveratrol treatment alleviated pathologies and downregulated NFκB expression in hippocampus. TBI caused adverse alterations in free radicals' balance system and histological structures of hippocampus. Resveratrol with its antioxidant and anti-inflammatory effects reduced the damage caused by TBI.

Published
2024
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