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4. Initial Laparotomy Versus Peritoneal Drainage in Extremely Low Birthweight Infants With Surgical Necrotizing Enterocolitis or Isolated Intestinal Perforation: A Multicenter Randomized Clinical Trial.

Author

Blakely, Martin L, Tyson, Jon E, Lally, Kevin P, Hintz, Susan R, Eggleston, Barry, Stevenson, David K, Besner, Gail E, Das, Abhik, Ohls, Robin K, Truog, William E, Nelin, Leif D, Poindexter, Brenda B, Pedroza, Claudia, Walsh, Michele C, Stoll, Barbara J, Geller, Rachel, Kennedy, Kathleen A, Dimmitt, Reed A, Carlo, Waldemar A, Cotten, C Michael, Laptook, Abbot R, Van Meurs, Krisa P, Calkins, Kara L, Sokol, Gregory M, Sanchez, Pablo J, Wyckoff, Myra H, Patel, Ravi M, Frantz, Ivan D, Shankaran, Seetha, D'Angio, Carl T, Yoder, Bradley A, Bell, Edward F, Watterberg, Kristi L, Martin, Colin A, Harmon, Carroll M, Rice, Henry, Kurkchubasche, Arlet G, Sylvester, Karl, Dunn, James CY, Markel, Troy A, Diesen, Diana L, Bhatia, Amina M, Flake, Alan, Chwals, Walter J, Brown, Rebeccah, Bass, Kathryn D, St Peter, Shawn D, Shanti, Christina M, Pegoli, Walter, Skarda, David, Shilyansky, Joel, Lemon, David G, Mosquera, Ricardo A, Peralta-Carcelen, Myriam, Goldstein, Ricki F, Vohr, Betty R, Purdy, Isabell B, Hines, Abbey C, Maitre, Nathalie L, Heyne, Roy J, DeMauro, Sara B, McGowan, Elisabeth C, Yolton, Kimberly, Kilbride, Howard W, Natarajan, Girija, Yost, Kelley, Winter, Sarah, Colaizy, Tarah T, Laughon, Matthew M, Lakshminrusimha, Satyanarayana, and Higgins, Rosemary D

Subjects
Perinatal Period - Conditions Originating in Perinatal Period, Clinical Research, Infant Mortality, Rare Diseases, Digestive Diseases, Preterm, Low Birth Weight and Health of the Newborn, Pediatric, Clinical Trials and Supportive Activities, Good Health and Well Being, Drainage, Enterocolitis, Necrotizing, Feasibility Studies, Female, Humans, Infant, Extremely Low Birth Weight, Infant, Newborn, Infant, Premature, Infant, Premature, Diseases, Intestinal Perforation, Laparotomy, Male, Neurodevelopmental Disorders, Survival Rate, Treatment Outcome, isolated intestinal perforation, neonatal surgery, premature infant, randomized clinical trial, surgical necrotizing enterocolitis, Eunice Kennedy Shriver National Institute of Child Health, Human Development Neonatal Research Network, Medical and Health Sciences, Surgery
Abstract

ObjectiveThe aim of this study was to determine which initial surgical treatment results in the lowest rate of death or neurodevelopmental impairment (NDI) in premature infants with necrotizing enterocolitis (NEC) or isolated intestinal perforation (IP).Summary background dataThe impact of initial laparotomy versus peritoneal drainage for NEC or IP on the rate of death or NDI in extremely low birth weight infants is unknown.MethodsWe conducted the largest feasible randomized trial in 20 US centers, comparing initial laparotomy versus peritoneal drainage. The primary outcome was a composite of death or NDI at 18 to 22 months corrected age, analyzed using prespecified frequentist and Bayesian approaches.ResultsOf 992 eligible infants, 310 were randomized and 96% had primary outcome assessed. Death or NDI occurred in 69% of infants in the laparotomy group versus 70% with drainage [adjusted relative risk (aRR) 1.0; 95% confidence interval (CI): 0.87-1.14]. A preplanned analysis identified an interaction between preoperative diagnosis and treatment group (P = 0.03). With a preoperative diagnosis of NEC, death or NDI occurred in 69% after laparotomy versus 85% with drainage (aRR 0.81; 95% CI: 0.64-1.04). The Bayesian posterior probability that laparotomy was beneficial (risk difference

Published
2021

5. Umbilical Cord Milking vs Delayed Cord Clamping and Associations with In-Hospital Outcomes among Extremely Premature Infants

Author

Kumbhat, Neha, Eggleston, Barry, Davis, Alexis S, DeMauro, Sara B, Van Meurs, Krisa P, Foglia, Elizabeth E, Lakshminrusimha, Satyan, Walsh, Michele C, Watterberg, Kristi L, Wyckoff, Myra H, Das, Abhik, Handley, Sara C, Network, Generic Database Subcommittee of the National Institute of Child Health and Human Development Neonatal Research, Polin, Richard A, Laptook, R, Keszler, Martin, Hensman, Angelita M, Vieira, Elisa, St. Pierre, Lucille, Hibbs, Anna Maria, Truog, William E, Pallotto, Eugenia K, Parimi, Prabhu S, Gauldin, Cheri, Holmes, Anne, Knutson, Allison, Gaetano, Lisa, Poindexter, Brenda B, Schibler, Kurt, Merhar, Stephanie L, Grisby, Cathy, Kirker, Kristin, Cotten, C Michael, Goldberg, Ronald N, Finkle, Joanne, Fisher, Kimberley A, Laughon, Matthew M, Bose, Carl L, Bernhardt, Janice, Bose, Gennie, Clark, Cindy, Kicklighter, Stephen D, Rhodes-Ryan, Ginger, White, Donna, Carlton, David P, Patel, Ravi M, Loggins, Yvonne, Mackie, Colleen, Bottcher, Diane I, Bremer, Andrew A, Higgins, Rosemary D, Archer, Stephanie Wilson, Sokol, Gregory M, Herron, Dianne E, Tyson, Jon E, Khan, Amir M, Kennedy, Kathleen A, Pedrozza, Claudia, Eason, Elizabeth, Stephens, Emily K, McDavid, Georgia E, Martin, Karen, Hall, Donna, Wright, Sharon L, Sánchez, Pablo J, Nelin, Leif D, Jadcherla, Sudarshan R, Luzader, Patricia, Clark, Erna, Gutentag, Julie, Park, Courtney, Shadd, Julie C, Stein, Melanie, Baugher, Hallie, McCool, Jacqueline, Gantz, Marie G, Bann, Carla M, Wallace, Dennis, Zaterka-Baxter, Kristin M, Gabrio, Jenna, Leblond, David, Auman, Jeanette O'Donnell, Stevenson, David K, Chock, Valerie Y, Ball, M Bethany, Proud, Melinda S, Reichert, Elizabeth N, Williams, R Jordan, Carlo, Waldemar A, Ambalavanan, Namasivayam, Collins, Monica V, Cosby, Shirley S, McNair, Tara, Devaskar, Uday, Garg, Meena, Chanlaw, Teresa, Geller, Rachel, Bell, Edward F, Colaizy, Tarah T, and Ellsbury, Dan L

Subjects
Paediatrics, Biomedical and Clinical Sciences, Prevention, Preterm, Low Birth Weight and Health of the Newborn, Infant Mortality, Clinical Research, Neurosciences, Cardiovascular, Clinical Trials and Supportive Activities, Perinatal Period - Conditions Originating in Perinatal Period, Pediatric, Reproductive health and childbirth, Good Health and Well Being, Cerebral Intraventricular Hemorrhage, Constriction, Female, Gestational Age, Hospital Mortality, Humans, Infant, Extremely Premature, Infant, Newborn, Male, Retrospective Studies, Umbilical Cord, Generic Database Subcommittee of the National Institute of Child Health and Human Development Neonatal Research Network, Neonatal Research Network, intraventricular hemorrhage, placental transfusion, Human Movement and Sports Sciences, Paediatrics and Reproductive Medicine, Pediatrics
Abstract

ObjectiveTo compare in-hospital outcomes after umbilical cord milking vs delayed cord clamping among infants

Published
2021

6. Early-Life Outcomes in Relation to Social Determinants of Health for Children Born Extremely Preterm

Author

Jobe, Alan H., Caplan, Michael S., Polin, Richard A., Laptook, Abbot R., Keszler, Martin, Hensman, Angelita M., Alksninis, Barbara, Bishop, Carmena, Burke, Robert T., Caskey, Melinda, Hoffman, Laurie, Johnson, Katharine, Keszler, Mary Lenore, Knoll, Andrea M., Lamberson, Vita, Leach, Teresa M., Little, Emilee, McGowan, Elisabeth C., Stephens, Bonnie E., Vieira, Elisa, St. Pierre, Lucille, Ventura, Suzy, Watson, Victoria E., Hibbs, Anna Maria, Walsh, Michele C., Wilson-Costello, Deanne E., Newman, Nancy S., Bhola, Monika, Payne, Allison H., Siner, Bonnie S., Yalcinkaya, Gulgun, Truog, William E., Pallotto, Eugenia K., Kilbride, Howard W., Gauldin, Cheri, Holmes, Anne, Johnson, Kathy, Scott, Allison, Parimi, Prabhu S., Gaetano, Lisa, Poindexter, Brenda B., Schibler, Kurt, Kallapur, Suhas G., Donovan, Edward F., Merhar, Stephanie, Grisby, Cathy, Yolton, Kimberly, Alexander, Barbara, Beiersdorfer, Traci, Bridges, Kate, Cahill, Tanya E., Dudley, Juanita, Fischer, Estelle E., Gratton, Teresa L., Hayes, Devan, Hessling, Jody, Jackson, Lenora D., Kirker, Kristin, Mincey, Holly L., Muthig, Greg, Stacey, Sara, Steichen, Jean J., Tepe, Stacey, Thompson, Julia, Wuertz, Sandra, Cotten, C. Michael, Goldberg, Ronald N., Goldstein, Ricki F., Malcolm, William F., Mago-Shah, Deesha, Ashley, Patricia L., Finkle, Joanne, Auten, Kathy J., Fisher, Kimberley A., Grimes, Sandra, Gustafson, Kathryn E., Lohmeyer, Melody B., Laughon, Matthew M., Bose, Carl L., Bernhardt, Janice, Bose, Gennie, Clark, Cindy, Talbert, Jennifer, Warner, Diane, Trembath, Andrea, O'Shea, T. Michael, Wereszczak, Janice, Kicklighter, Stephen D., Rhodes-Ryan, Ginger, White, Donna, Patel, Ravi M., Carlton, David P., Stoll, Barbara J., Hale, Ellen C., Loggins, Yvonne C., Adams-Chapman, Ira, Blackwelder, Ann, Bottcher, Diane I., Carter, Sheena L., Kendrick-Allwood, Salathiel, Laursen, Judith, LaRossa, Maureen Mulligan, Mackie, Colleen, Sanders, Amy, Seabrook, Irma, Smikle, Gloria, Wineski, Lynn C., Higgins, Rosemary D., Bremer, Andrew A., Archer, Stephanie Wilson, Sokol, Gregory M., Dusick, Anna M., Papile, Lu Ann, Gunn, Susan, Hamer, Faithe, Harmon, Heidi M., Herron, Dianne E., Hines, Abbey C., Lytle, Carolyn, Miller, Lucy C., Minnich, Heike M., Richard, Leslie, Smiley, Lucy, Wilson, Leslie Dawn, Tyson, Jon E., Kennedy, Kathleen A., Khan, Amir M., Duncan, Andrea, Mosquera, Ricardo, Stephens, Emily K., McDavid, Georgia E., Alaniz, Nora I., Allain, Elizabeth, Arldt-McAlister, Julie, Burson, Katrina, Dempsey, Allison G., Eason, Elizabeth, Evans, Patricia W., Garcia, Carmen, Green, Charles, Hall, Donna, Harris, Beverly Foley, Jiminez, Margarita, John, Janice, Jones, Patrick M., Lillie, M. Layne, Lis, Anna E., Martin, Karen, Martin, Sara C., Mason, Carrie M., McKee, Shannon, Morris, Brenda H., Rennie, Kimberly, Rodgers, Shawna, Siddiki, Saba Khan, Simmons, Maegan C., Sperry, Daniel, Pierce Tate, Patti L., Wright, Sharon L., Sánchez, Pablo J., Nelin, Leif D., Jadcherla, Sudarshan R., Slaughter, Jonathan L., Yeates, Keith O., Keim, Sarah, Maitre, Nathalie L., Timan, Christopher J., Luzader, Patricia, Clark, Erna, Fortney, Christine A., Gutentag, Julie, Park, Courtney, Shadd, Julie, Sullivan, Margaret, Stein, Melanie, Nelin, Mary Ann, Newton, Julia, Small, Kristi, Burkhardt, Stephanie, Purnell, Jessica, Pietruszewski, Lindsay, Levengood, Katelyn, Batterson, Nancy, Morehead, Pamela, Carey, Helen, Yoseff-Salameh, Lina, Sullivan, Rox Ann, Hague, Cole, Grothause, Jennifer, Fearns, Erin, Fowler, Aubrey, Notestine, Jennifer, Tonneman, Jill, Hay, Krystal, Chao, Michelle, Warnimont, Kyrstin, Marzec, Laura, Miller, Bethany, Beckford, Demi R., Baugher, Hallie, DeSantis, Brittany, Hanlon, Cory, McCool, Jacqueline, Das, Abhik, Gantz, Marie G., Bann, Carla M., Wallace, Dennis, Crawford, Margaret M., Gabrio, Jenna, Leblond, David, Newman, Jamie E., Petrie Huitema, Carolyn M., O'Donnell Auman, Jeanette, Poole, W. Kenneth, Zaterka-Baxter, Kristin M., Van Meurs, Krisa P., Chock, Valerie Y., Stevenson, David K., Adams, Marian M., Ball, M. Bethany, Bentley, Barbara, Bruno, Elizabeth, Davis, Alexis S., Elena DeAnda, Maria, DeBattista, Anne M., Huffman, Lynne C., Ismael, Magdy, Kohn, Jean G., Krueger, Casey, Lowe, Janice, Lucash, Ryan E., Palmquist, Andrew W., Patel, Jessica, Proud, Melinda S., Reichert, Elizabeth N., John, Nicholas H. St., Sivakumar, Dharshi, Taylor, Heather L., Wager, Natalie, Williams, R. Jordan, Weiss, Hali, Frantz, Ivan D., III, Fiascone, John M., MacKinnon, Brenda L., Furey, Anne, Nylen, Ellen, Church, Paige T., Sibley, Cecelia E., Brussa, Ana K., Carlo, Waldemar A., Ambalavanan, Namasivayam, Peralta-Carcelen, Myriam, Nelson, Kathleen G., Bailey, Kirstin J., Biasini, Fred J., Chopko, Stephanie A., Collins, Monica V., Cosby, Shirley S., Johnston, Kristen C., Moses, Mary Beth, Patterson, Cryshelle S., Phillips, Vivien A., Preskitt, Julie, Rector, Richard V., Whitley, Sally, Devaskar, Uday, Garg, Meena, Purdy, Isabell B., Chanlaw, Teresa, Geller, Rachel, Finer, Neil N., Vaucher, Yvonne E., Kaegi, David, Rasmussen, Maynard R., Arnell, Kathy, Demetrio, Clarence, Fuller, Martha G., Rich, Wade, Bell, Edward F., Colaizy, Tarah T., Widness, John A., Brumbaugh, Jane E., Acarregui, Michael J., Johnson, Karen J., Eastman, Diane L., Goeke, Claire A., Schmelzel, Mendi L., Walker, Jacky R., Baack, Michelle L., Hogden, Laurie A., Broadbent, Megan, Elenkiwich, Chelsey, Henning, Megan M., Van Muyden, Sarah, Ellsbury, Dan L., Campbell, Donia B., Tud, Tracy L., Duara, Shahnaz, Bauer, Charles R., Everett-Thomas, Ruth, Fajardo-Hiriart, Sylvia, Rigaud, Arielle, Calejo, Maria, Frade Eguaras, Silvia M., Berkowits, Michelle Harwood, Garcia, Andrea, Pierre, Helina, Stoerger, Alexandra, Watterberg, Kristi L., Fuller, Janell, Ohls, Robin K., Beauman, Sandra Sundquist, Lacy, Conra Backstrom, Duncan, Andrea F., Hanson, Mary, Hartenberger, Carol, Kuan, Elizabeth, Lowe, Jean R., Thomson, Rebecca A., DeMauro, Sara B., Eichenwald, Eric C., Schmidt, Barbara, Kirpalani, Haresh, Chaudhary, Aasma S., Abbasi, Soraya, Mancini, Toni, Catts, Christine, Cook, Noah, Cucinotta, Dara M., Bernbaum, Judy C., Gerdes, Marsha, Ghavam, Sarvin, Hurt, Hallam, Snyder, Jonathan, Vangala, Saritha, Ziolkowski, Kristina, D'Angio, Carl T., Phelps, Dale L., Guillet, Ronnie, Myers, Gary J., Andrews-Hartley, Michelle, Johnson, Julie Babish, Binion, Kyle, Bowman, Melissa, Boylin, Elizabeth, Burnell, Erica, Coleman, Kelly R., Fallone, Cait, Farooq, Osman, Hunn, Julianne, Hust, Diane, Jensen, Rosemary L., Jones, Rachel, Kachelmeyer, Jennifer, Kushner, Emily, Maffett, Deanna, McKee, Kimberly G., Merzbach, Joan, Orme, Constance, Prinzing, Diane, Reubens, Linda J., Rochez, Daisy, Rowan, Mary, Sabaratnam, Premini, Scorsone, Ann Marie, Wadkins, Holly I.M., Yost, Kelley, Zwetsch, Lauren, Lakshminrusimha, Satyan, Reynolds, Anne Marie, Sacilowski, Michael G., Guilford, Stephanie, Li, Emily, Williams, Ashley, Zorn, William A., Wyckoff, Myra H., Brion, Luc P., Salhab, Walid A., Rosenfeld, Charles R., Heyne, Roy J., Vasil, Diana M., Adams, Sally S., Chen, Lijun, De Leon, Maria M., Eubanks, Francis, Guzman, Alicia, Hensley, Gaynelle, Heyne, Elizabeth T., Lee, Lizette E., Leps, Melissa H., Madden, Linda A., McDougald, E. Rebecca, Miller, Nancy A., Morgan, Janet S., Pavageau, Lara, Sepulveda, Pollieanna, Tolentino-Plata, Kristine, Boatman, Cathy Twell, Vera, Azucena, Waterbury, Jillian, Yoder, Bradley A., Baserga, Mariana, Faix, Roger G., Winter, Sarah, Minton, Stephen D., Sheffield, Mark J., Rau, Carrie A., Baker, Shawna, Bird, Karie, Burnett, Jill, Christensen, Susan, Cole-Bledsoe, Laura, Davis, Brandy, Elmont, Jennifer O., Jensen, Jennifer J., Loertscher, Manndi C., Jordan, Jamie, Marchant, Trisha, Maxson, Earl, McGrath, Kandace M., Osborne, Karen A., Parry, D. Melody, Reich, Brixen A., Schaefer, Susan T., Spencer, Cynthia, Steffen, Michael, Tice, Katherine, Weaver-Lewis, Kimberlee, Woodbury, Kathryn D., Zanetti, Karen, Dillard, Robert G., Washburn, Lisa K., Jackson, Barbara G., Peters, Nancy, Chiu, Korinne, Allred, Deborah Evans, Goldstein, Donald J., Halfond, Raquel, Peterson, Carroll, Waldrep, Ellen L., Welch, Cherrie D., Morris, Melissa Whalen, Hounshell, Gail Wiley, Shankaran, Seetha, Sood, Beena G., Natarajan, Girija, Pappas, Athina, Abramczyk, Katherine, Agarwal, Prashant, Bajaj, Monika, Bara, Rebecca, Billian, Elizabeth, Chawla, Sanjay, Childs, Kirsten, De Jesus, Lilia C., Driscoll, Debra, February, Melissa, Goldston, Laura A., Johnson, Mary E., Muran, Geraldine, Panaitescu, Bogdan, Prentiss, Jeannette E., White, Diane, Woldt, Eunice, Barks, John, Wiggins, Stephanie A., Christensen, Mary K., Carlson, Martha D., Ehrenkranz, Richard A., Jacobs, Harris, Butler, Christine G., Cervone, Patricia, Greisman, Sheila, Konstantino, Monica, Poulsen, JoAnn, Taft, Janet, Williams, Joanne, Romano, Elaine, Vohr, Betty R., Travers, Colm P., and Hintz, Susan R.

Published
2023
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7. Surfactant status and respiratory outcome in premature infants receiving late surfactant treatment

Author

Ballard, Philip L, Keller, Roberta L, Truog, William E, Chapin, Cheryl, Horneman, Hart, Segal, Mark R, Ballard, Roberta A, and Tolsurf Investigators

Subjects
Paediatrics, Biomedical and Clinical Sciences, Infant Mortality, Preterm, Low Birth Weight and Health of the Newborn, Perinatal Period - Conditions Originating in Perinatal Period, Pediatric, Clinical Research, Lung, Neonatal Respiratory Distress, Birth Weight, Bronchopulmonary Dysplasia, Drug Administration Schedule, Female, Humans, Infant, Infant, Newborn, Infant, Premature, Infant, Premature, Diseases, Male, Phospholipids, Pulmonary Surfactant-Associated Protein B, Pulmonary Surfactants, Respiration, Tolsurf Investigators, Paediatrics and Reproductive Medicine, Public Health and Health Services, Pediatrics
Abstract

BackgroundMany premature infants with respiratory failure are deficient in surfactant, but the relationship to occurrence of bronchopulmonary dysplasia (BPD) is uncertain.MethodsTracheal aspirates were collected from 209 treated and control infants enrolled at 7-14 days in the Trial of Late Surfactant. The content of phospholipid, surfactant protein B, and total protein were determined in large aggregate (active) surfactant.ResultsAt 24 h, surfactant treatment transiently increased surfactant protein B content (70%, p

Published
2019

8. Surgical Necrotizing Enterocolitis and Spontaneous Intestinal Perforation Lead to Severe Growth Failure in Infants.

Author

Speer, Allison L., Lally, Kevin P., Pedroza, Claudia, Yuxin Zhang, Poindexter, Brenda B., Chwals, Walter J., Hintz, Susan R., Besner, Gail E., Stevenson, David K., Ohls, Robin K., Truog, William E., Stoll, Barbara J., Rysavy, Matthew A., Das, Abhik, Tyson, Jon E., and Blakely, Martin L.

Abstract

Objective: We aimed to determine the incidence of growth failure in infants with necrotizing enterocolitis (NEC) or spontaneous intestinal perforation (SIP) and whether initial laparotomy versus peritoneal drainage (PD) impacted the likelihood of growth failure. Summary Background Data: Infants with surgical NEC and SIP have high mortality, and most have neurodevelopmental impairment and poor growth. Existing literature on growth outcomes for these infants is limited. Methods: This is a preplanned secondary study of the Necrotizing Enterocolitis Surgery Trial dataset. The primary outcome was growth failure (Z-score for weight < -2.0) at 18 to 22 months. We used logistic regression, including diagnosis and treatment, as covariates. Secondary outcomes were analyzed using the Fisher exact or Pearson χ² test for categorical variables and the Wilcoxon rank sum test or one-way ANOVA for continuous variables. Results: Among 217 survivors, 207 infants (95%) had primary outcome data. Growth failure at 18 to 22 months occurred in 24/50 (48%) of NEC infants versus 65/157 (42%) SIP (P=0.4). The mean weight-for-age Z-score at 18 to 22 months in NEC infants was -2.05±0.99 versus -1.84±1.09 SIP (P= 0.2), and the predicted mean weight-for-age Z-score SIP (Beta -0.27; 95% CI: -0.53, -0.01; P=0.041). Median declines in weight-for-age Z-score between birth and 18 to 22 months were significant in all infants but most severe (>2) in NEC infants (P=0.2). Conclusions: This first ever prospective study of growth outcomes in infants with surgical NEC or SIP demonstrates that growth failure is very common, especially in infants with NEC, and persists at 18-22 months. [ABSTRACT FROM AUTHOR]

Published
2024
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10. Maternal Black Race and Persistent Wheezing Illness in Former Extremely Low Gestational Age Newborns: Secondary Analysis of a Randomized Trial

Author

Wai, Katherine C, Hibbs, Anna M, Steurer, Martina A, Black, Dennis M, Asselin, Jeanette M, Eichenwald, Eric C, Ballard, Philip L, Ballard, Roberta A, Keller, Roberta L, Group, Trial of Late Surfactant Study, Strong, Suzanne Hamilton, Immamura-Ching, Jill, Orfanos-Villalobos, Margaret, Williams, Cassandra, Durand, David J, Merrill, Jeffrey D, Horton, Dolia, Pacello, Loretta, Willard, April, Truog, William E, Gauldin, Cheryl, Holmes, Anne, Johnson, Patrice, Meinert, Kerrie, Reynolds, Anne Marie, Lucie, Janine, Conway, Patrick, Sacilowski, Michael, Leadersdorff, Michael, Orbank, Pam, Wynn, Karen, Steinhorn, Robin H, deUngria, Maria, Khan, Janine Yasmin, Hamann, Karin, Schau, Molly, Hopkins, Brad, Jenson, James, Garcia, Carmen, Parekh, Aruna, Shariff, Jila, McGovern, Rose, Adelman, Jeff, Combs, Adrienne, Tjersland, Mary, Mayock, Dennis E, Howland, Elizabeth, Walker, Susan, Longoria, Jim, Meo, Holly, Khan, Amir, McDavid, Georgia, Burson, Katrina, Hinojosa, Richard, Johnson, Christopher, Martin, Karen, Martin, Sarah, Rogers, Shawna, Wright, Sharon, Hudak, Mark L, Barnette, Kimberly, Kellum, Amanda, Burcke, Michelle, Hayes, Christie, Chadwick, Stephanie, Howard, Danielle, Kennedy, Carla, Prince, Renee, Helderman, Jennifer, O'Shea, T Michael, Stefanescu, Beatrice, Warden, Kelly, Brown, Patty, Griffin, Jennifer, Conley, Laura, Bendel, Catherine M, Georgieff, Michael, Davern, Bridget, Mills, Marla, Ritter, Sharon, Wagner, Carol, Ryan, Rita M, Fanning, Deanna, Roberson, Jimmy, Mammel, Mark C, Lampland, Andrea, Meyers, Pat, Brey, Angela, Bendel-Stenzel, Ellen M, Mulrooney, Neil, Worwa, Cathy, Dixon, Pam, Ebert, Gerald, Hejl, Cathy, Maxwell, Molly, McCullough, Kristin, Dhanireddy, Ramasubbareddy, Abiad, Mohammed T El, Talati, Ajay, and Dempsey, Sheila

Subjects
Paediatrics, Reproductive Medicine, Biomedical and Clinical Sciences, Asthma, Prevention, Preterm, Low Birth Weight and Health of the Newborn, Lung, Behavioral and Social Science, Clinical Research, Nutrition, Pediatric, Perinatal Period - Conditions Originating in Perinatal Period, Women's Health, Clinical Trials and Supportive Activities, Minority Health, Black or African American, Child, Preschool, Female, Humans, Infant, Infant, Extremely Premature, Infant, Newborn, Infant, Premature, Diseases, Male, Mothers, Respiration, Artificial, Respiratory Sounds, Risk Factors, Trial of Late Surfactant (TOLSURF) Study Group, asthma, prematurity, socioeconomic factors, Human Movement and Sports Sciences, Paediatrics and Reproductive Medicine, Pediatrics
Abstract

ObjectiveTo evaluate the relationship between maternal self-reported race/ethnicity and persistent wheezing illness in former high-risk, extremely low gestational age newborns, and to quantify the contribution of socioeconomic, environmental, and biological factors on this relationship.Study designWe assessed persistent wheezing illness determined at 18-24 months corrected (for prematurity) age in survivors of a randomized trial. Parents/caregivers were surveyed for wheeze and inhaled asthma medication use quarterly to 12 months, and at 18 and 24 months. We used multivariable analysis to evaluate the relationship of maternal race to persistent wheezing illness, and identified mediators for this relationship via formal mediation analysis.ResultsOf 420 infants (25.2 ± 1.2 weeks of gestation and 714 ± 166 g at birth, 57% male, 34% maternal black race), 189 (45%) had persistent wheezing illness. After adjustment for gestational age, birth weight, and sex, infants of black mothers had increased odds of persistent wheeze compared with infants of nonblack mothers (OR = 2.9, 95% CI 1.9, 4.5). Only bronchopulmonary dysplasia, breast milk diet, and public insurance status were identified as mediators. In this model, the direct effect of race accounted for 69% of the relationship between maternal race and persistent wheeze, whereas breast milk diet, public insurance status, and bronchopulmonary dysplasia accounted for 8%, 12%, and 10%, respectively.ConclusionsAmong former high-risk extremely low gestational age newborns, infants of black mothers have increased odds of developing persistent wheeze. A substantial proportion of this effect is directly accounted for by race, which may reflect unmeasured environmental influences, and acquired and innate biological differences.Trial registrationClinicalTrials.gov: NCT01022580.

Published
2018

11. Delivery Room Resuscitation and Short-Term Outcomes in Moderately Preterm Infants

Author

Bajaj, Monika, Natarajan, Girija, Shankaran, Seetha, Wyckoff, Myra, Laptook, R, Bell, Edward F, Stoll, Barbara J, Carlo, Waldemar A, Vohr, Betty R, Saha, Shampa, Van Meurs, Krisa P, Sanchez, Pablo J, D'Angio, Carl T, Higgins, Rosemary D, Das, Abhik, Newman, Nancy, Walsh, Michele C, Network, Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research, Polin, Richard A, Keszler, Martin, Hensman, Angelita M, Vieira, Elisa, Hibbs, Anna Marie, Siner, Bonnie S, Truog, William E, Pallotto, Eugenia K, Kilbride, Howard W, Gauldin, Cheri, Holmes, Anne, Johnson, Kathy, Poindexter, Brenda B, Schibler, Kurt, Kallapur, Suhas G, Grisby, Cathy, Alexander, Barbara, Fischer, Estelle E, Jackson, Lenora, Kirker, Kristin, Jennings, Jennifer, Wuertz, Sandra, Muthig, Greg, Cotten, C Michael, Goldberg, Ronald N, Finkle, Joanne, Fisher, Kimberley A, Laughon, Matthew M, Bose, Carl L, Bernhardt, Janice, Clark, Cindy, Carlton, David P, Hale, Ellen C, Loggins, Yvonne, Bottcher, Diane I, Archer, Stephanie Wilson, Sokol, Greg, Herron, Dianne E, Nelin, Leif D, Jadcherla, Sudarshan R, Luzader, Patricia, Parikh, Nehal A, Nist, Marliese Dion, Fuller, Jennifer, Gutentag, Julie, Jones, Marissa E, McGregor, Sarah, Rodgers, Elizabeth, Ulloa, Jodi A, Wolfe, Tara, Wallace, Dennis, Zaterka-Baxter, Kristin M, Crawford, Margaret, Gabrio, Jenna, Kandefer, Sarah, Auman, Jeanette O'Donnell, Stevenson, David K, Ball, M Bethany, Proud, Melinda S, Ambalavanan, Namasivayam, Collins, Monica V, Cosby, Shirley S, Devaskar, Uday, Garg, Meena, Chanlaw, Teresa, Geller, Rachel, Colaizy, Tarah T, Ellsbury, Dan L, Brumbaugh, Jane E, Johnson, Karen J, Campbell, Donia B, Walker, Jacky R, Watterberg, Kristi L, Ohls, Robin K, Lacy, Conra Backstrom, Beauman, Sandy Sundquist, Hartenberger, Carol, Schmidt, Barbara, Kirpalani, Haresh, DeMauro, Sara B, Cook, Noah, and Chaudhary, Aasma S

Subjects
Paediatrics, Biomedical and Clinical Sciences, Preterm, Low Birth Weight and Health of the Newborn, Pediatric, Perinatal Period - Conditions Originating in Perinatal Period, Infant Mortality, Lung, Clinical Research, Reproductive health and childbirth, Good Health and Well Being, Cardiopulmonary Resuscitation, Continuous Positive Airway Pressure, Delivery Rooms, Female, Humans, Infant, Newborn, Infant, Premature, Infant, Small for Gestational Age, Intubation, Intratracheal, Male, Outcome Assessment, Health Care, Oxygen Inhalation Therapy, Prospective Studies, Registries, Risk Factors, Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network, CPR, delivery room, endotracheal intubation, moderate Preterm, oxygen, resuscitation, Human Movement and Sports Sciences, Paediatrics and Reproductive Medicine, Pediatrics
Abstract

ObjectivesTo describe the frequency and extent of delivery room resuscitation and evaluate the association of delivery room resuscitation with neonatal outcomes in moderately preterm (MPT) infants.Study designThis was an observational cohort study of MPT infants delivered at 290/7 to 336/7 weeks' gestational age (GA) enrolled in the Neonatal Research Network MPT registry. Infants were categorized into 5 groups based on the highest level of delivery room intervention: routine care, oxygen and/or continuous positive airway pressure, bag and mask ventilation, endotracheal intubation, and cardiopulmonary resuscitation including chest compressions and/or epinephrine use. The association of antepartum and intrapartum risk factors and discharge outcomes with the intensity of resuscitation was evaluated.ResultsOf 7014 included infants, 1684 (24.0%) received routine care and no additional resuscitation, 2279 (32.5%) received oxygen or continuous positive airway pressure, 1831 (26.1%) received bag and mask ventilation, 1034 (14.7%) underwent endotracheal intubation, and 186 (2.7%) received cardiopulmonary resuscitation. Among the antepartum and intrapartum factors, increasing GA, any exposure to antenatal steroids and prolonged rupture of membranes decreased the likelihood of receipt of all levels of resuscitation. Infants who were small for GA (SGA) had increased risk of delivery room resuscitation. Among the neonatal outcomes, respiratory support at 28 days, days to full oral feeds and length of stay were significantly associated with the intensity of delivery room resuscitation. Higher intensity of resuscitation was associated with increased risk of mortality.ConclusionsThe majority of MPT infants receive some level of delivery room resuscitation. Increased intensity of delivery room interventions was associated with prolonged respiratory and nutritional support, increased mortality, and a longer length of stay.

Published
2018

12. Admission Temperature and Associated Mortality and Morbidity among Moderately and Extremely Preterm Infants

Author

Laptook, R, Bell, Edward F, Shankaran, Seetha, Boghossian, Nansi S, Wyckoff, Myra H, Kandefer, Sarah, Walsh, Michele, Saha, Shampa, Higgins, Rosemary, Network, Generic and Moderate Preterm Subcommittees of the NICHD Neonatal Research, Polin, Richard A, Keszler, Martin, Vohr, Betty R, Hensman, Angelita M, Vieira, Elisa, Little, Emilee, Fanaroff, Avroy A, Hibbs, Anna Marie, Newman, Nancy S, Siner, Bonnie S, Truog, William E, Pallotto, Eugenia K, Kilbride, Howard W, Gauldin, Cheri, Holmes, Anne, Johnson, Kathy, Schibler, Kurt, Kallapur, Suhas G, Grisby, Cathy, Alexander, Barbara, Fischer, Estelle E, Jackson, Lenora, Kirker, Kristin, Jennings, Jennifer, Wuertz, Sandra, Muthig, Greg, Donovan, Edward F, Hessling, Jody, Mersmann, Marcia Worley, Mincey, Holly L, Cotten, C Michael, Goldberg, Ronald N, Finkle, Joanne, Fisher, Kimberley A, Auten, Kathy J, Laughon, Matthew M, Bose, Carl L, Bernhardt, Janice, Clark, Cindy, Stoll, Barbara J, Carlton, David P, Hale, Ellen C, Loggins, Yvonne, Bottcher, Diane I, Archer, Stephanie Wilson, Wright, Linda L, McClure, Elizabeth M, Poindexter, Brenda B, Sokol, Gregory M, Herron, Dianne E, Lemons, James A, Appel, Diana D, Miller, Lucy C, Sanchez, Pablo J, Nelin, Leif D, Jadcherla, Sudarshan R, Luzader, Patricia, Parikh, Nehal A, Nist, Marliese Dion, Fuller, Jennifer, Gutentag, Julie, Jones, Marissa E, McGregor, Sarah, Rodgers, Elizabeth, Ulloa, Jodi A, Wolfe, Tara, Das, Abhik, Wallace, Dennis, Poole, W Kenneth, Zaterka-Baxter, Kristin M, Crawford, Margaret, Gabrio, Jenna, Auman, Jeanette O'Donnell, Huitema, Carolyn Petrie, Hastings, Betty K, Van Meurs, Krisa P, Stevenson, David K, Ball, M Bethany, Proud, Melinda S, Carlo, Waldemar A, Ambalavanan, Namasivayam, Collins, Monica V, Cosby, Shirley S, Devaskar, Uday, Garg, Meena, Chanlaw, Teresa, Geller, Rachel, Colaizy, Tarah T, Ellsbury, Dan L, and Brumbaugh, Jane E

Subjects
Paediatrics, Biomedical and Clinical Sciences, Perinatal Period - Conditions Originating in Perinatal Period, Infant Mortality, Pediatric, Clinical Research, Preterm, Low Birth Weight and Health of the Newborn, Reproductive health and childbirth, Good Health and Well Being, Body Temperature, Female, Fever, Hospital Mortality, Humans, Hypothermia, Infant, Extremely Premature, Infant, Newborn, Infant, Premature, Diseases, Intensive Care Units, Neonatal, Logistic Models, Male, Patient Admission, Risk Factors, United States, Generic and Moderate Preterm Subcommittees of the NICHD Neonatal Research Network, hyperthermia, hypothermia, prematurity, survival, Human Movement and Sports Sciences, Paediatrics and Reproductive Medicine, Pediatrics
Abstract

ObjectiveTo evaluate the temperature distribution among moderately preterm (MPT, 29-33 weeks) and extremely preterm (EPT, 37.5°C (4.2% vs 6.2%). For EPT infants in 2012-2013 compared with 2002-2003, the percentage of temperatures between 36.5°C and 37.5°C more than doubled and the percentage of temperatures >37.5°C more than tripled. Admission temperature was inversely associated with in-hospital mortality.ConclusionsLow and high admission temperatures are more frequent among EPT than MPT infants. Compared with a decade earlier, fewer EPT infants experience low admission temperatures but more have elevated temperatures. In spite of a change in distribution of NICU admission temperature, an inverse association between temperature and mortality risk persists.

Published
2018

15. Umbilical Cord Milking vs Delayed Cord Clamping and Associations with In-Hospital Outcomes among Extremely Premature Infants

Author

Polin, Richard A., Laptook, Abbot R., Keszler, Martin, Hensman, Angelita M., Vieira, Elisa, Pierre, Lucille St., Hibbs, Anna Maria, Truog, William E., Pallotto, Eugenia K., Parimi, Prabhu S., Gauldin, Cheri, Holmes, Anne, Knutson, Allison, Gaetano, Lisa, Poindexter, Brenda B., Schibler, Kurt, Merhar, Stephanie L., Grisby, Cathy, Kirker, Kristin, Cotten, C. Michael, Goldberg, Ronald N., Finkle, Joanne, Fisher, Kimberley A., Laughon, Matthew M., Bose, Carl L., Bernhardt, Janice, Bose, Gennie, Clark, Cindy, Kicklighter, Stephen D., Rhodes-Ryan, Ginger, White, Donna, Carlton, David P., Patel, Ravi M., Loggins, Yvonne, Mackie, Colleen, Bottcher, Diane I., Bremer, Andrew A., Higgins, Rosemary D., Wilson Archer, Stephanie, Sokol, Gregory M., Herron, Dianne E., Tyson, Jon E., Khan, Amir M., Kennedy, Kathleen A., Pedrozza, Claudia, Eason, Elizabeth, Stephens, Emily K., McDavid, Georgia E., Martin, Karen, Hall, Donna, Wright, Sharon L., Sánchez, Pablo J., Nelin, Leif D., Jadcherla, Sudarshan R., Luzader, Patricia, Clark, Erna, Gutentag, Julie, Park, Courtney, Shadd, Julie C., Stein, Melanie, Baugher, Hallie, McCool, Jacqueline, Gantz, Marie G., Bann, Carla M., Wallace, Dennis, Zaterka-Baxter, Kristin M., Gabrio, Jenna, Leblond, David, Auman, Jeanette O'Donnell, Stevenson, David K., Chock, Valerie Y., Ball, M. Bethany, Proud, Melinda S., Reichert, Elizabeth N., Williams, R. Jordan, Carlo, Waldemar A., Ambalavanan, Namasivayam, Collins, Monica V., Cosby, Shirley S., McNair, Tara, Devaskar, Uday, Garg, Meena, Chanlaw, Teresa, Geller, Rachel, Bell, Edward F., Colaizy, Tarah T., Ellsbury, Dan L., Baack, Michelle L., Johnson, Karen J., Schmelzel, Mendi L., Walker, Jacky R., Goeke, Claire A., Tud, Tracy L., Elenkiwich, Chelsey, Henning, Megan M., Broadbent, Megan, Hogden, Laurie A., Brumbaugh, Jane E., Klein, Jonathan M., Dagle, John M., Fuller, Janell, Ohls, Robin K., Sundquist Beauman, Sandra, Backstrom Lacy, Conra, Hartenberger, Carol, Hanson, Mary, Kuan, Elizabeth, Eichenwald, Eric C., Schmidt, Barbara, Kirpalani, Haresh, Abbasi, Soraya, Catts, Christine, Chaudhary, Aasma S., Ghavam, Sarvin, Mancini, Toni, Snyder, Jonathan, D'Angio, Carl T., Guillet, Ronnie, Reynolds, Anne Marie, Wadkins, Holly I.M., Sacilowski, Michael G., Rowan, Mary, Jensen, Rosemary L., Maffett, Deanna, Prinzing, Diane, Scorsone, Ann Marie, Binion, Kyle, Guilford, Stephanie, Orme, Constance, Sabaratnam, Premini, Daisy Rochez, Li, Emily, Donato, Jennifer, Lakshminrusimha, Satyan, Jones, Rachel, Brion, Luc P., DeLeon, Maria M., Eubanks, Frances, Sepulvida, Pollieanna, Vasil, Diana M., Yoder, Bradley A., Baserga, Mariana, Minton, Stephen D., Sheffield, Mark J., Rau, Carrie A., Burnett, Jill, Davis, Brandy, Christensen, Susan, Loertscher, Manndi C., Marchant, Trisha, Maxson, Earl, McGrath, Kandace, Elmont, Jennifer O., Parry, Melody, Schaefer, Susan T., Weaver-Lewis, Kimberlee, Woodbury, Kathryn D., Shankaran, Seetha, Natarajan, Girija, Chawla, Sanjay, Childs, Kirsten, Panaitescu, Bogdan, Barks, John, White, Diane F., Kumbhat, Neha, Eggleston, Barry, Davis, Alexis S., DeMauro, Sara B., Van Meurs, Krisa P., Foglia, Elizabeth E., Walsh, Michele C., Watterberg, Kristi L., Wyckoff, Myra H., Das, Abhik, and Handley, Sara C.

Published
2021
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16. The Randomized, Controlled Trial of Late Surfactant: Effects on Respiratory Outcomes at 1-Year Corrected Age

Author

Keller, Roberta L, Eichenwald, Eric C, Hibbs, Anna Maria, Rogers, Elizabeth E, Wai, Katherine C, Black, Dennis M, Ballard, Philip L, Asselin, Jeanette M, Truog, William E, Merrill, Jeffrey D, Mammel, Mark C, Steinhorn, Robin H, Ryan, Rita M, Durand, David J, Bendel, Catherine M, Bendel-Stenzel, Ellen M, Courtney, Sherry E, Dhanireddy, Ramasubbareddy, Hudak, Mark L, Koch, Frances R, Mayock, Dennis E, McKay, Victor J, Helderman, Jennifer, Porta, Nicolas F, Wadhawan, Rajan, Palermo, Lisa, Ballard, Roberta A, and Group, TOLSURF Study

Subjects
Paediatrics, Biomedical and Clinical Sciences, Preterm, Low Birth Weight and Health of the Newborn, Pediatric, Perinatal Period - Conditions Originating in Perinatal Period, Lung, Clinical Research, Clinical Trials and Supportive Activities, 6.1 Pharmaceuticals, Reproductive health and childbirth, Administration, Inhalation, Age Factors, Bronchopulmonary Dysplasia, Confidence Intervals, Dose-Response Relationship, Drug, Double-Blind Method, Drug Administration Schedule, Female, Follow-Up Studies, Gestational Age, Humans, Infant, Infant, Extremely Low Birth Weight, Infant, Newborn, Male, Nitric Oxide, Pulmonary Surfactants, Respiration, Artificial, Respiratory Distress Syndrome, Newborn, Risk Assessment, Survival Rate, Time Factors, TOLSURF Study Group, bronchopulmonary dysplasia, prematurity, pulmonary morbidity, wheeze, Human Movement and Sports Sciences, Paediatrics and Reproductive Medicine, Pediatrics
Abstract

ObjectiveTo determine the effects of late surfactant on respiratory outcomes determined at 1-year corrected age in the Trial of Late Surfactant (TOLSURF), which randomized newborns of extremely low gestational age (≤28 weeks' gestational age) ventilated at 7-14 days to late surfactant and inhaled nitric oxide vs inhaled nitric oxide-alone (control).Study designCaregivers were surveyed in a double-blinded manner at 3, 6, 9, and 12 months' corrected age to collect information on respiratory resource use (infant medication use, home support, and hospitalization). Infants were classified for composite outcomes of pulmonary morbidity (no PM, determined in infants with no reported respiratory resource use) and persistent PM (determined in infants with any resource use in ≥3 surveys).ResultsInfants (n = 450, late surfactant n = 217, control n = 233) were 25.3 ± 1.2 weeks' gestation and 713 ± 164 g at birth. In the late surfactant group, fewer infants received home respiratory support than in the control group (35.8% vs 52.9%, relative benefit [RB] 1.28 [95% CI 1.07-1.55]). There was no benefit of late surfactant for No PM vs PM (RB 1.27; 95% CI 0.89-1.81) or no persistent PM vs persistent PM (RB 1.01; 95% CI 0.87-1.17). After adjustment for imbalances in baseline characteristics, relative benefit of late surfactant treatment increased: RB 1.40 (95% CI 0.89-1.80) for no PM and RB 1.24 (95% CI 1.08-1.42) for no persistent PM.ConclusionTreatment of newborns of extremely low gestational age with late surfactant in combination with inhaled nitric oxide decreased use of home respiratory support and may decrease persistent pulmonary morbidity.Trial registrationClinicalTrials.gov: NCT01022580.

Published
2017

17. Behavior Profiles at 2 Years for Children Born Extremely Preterm with Bronchopulmonary Dysplasia

Author

Caplan, Michael S., Polin, Richard A., Laptook, Abbot R., Keszler, Martin, Hensman, Angelita M., Vieira, Elisa, Little, Emilee, Burke, Robert T., Stephens, Bonnie E., Alksninis, Barbara, Bishop, Carmena, Keszler, Mary L., Leach, Teresa M., Watson, Victoria E., Knoll, Andrea M., Walsh, Michele C., Fanaroff, Avroy A., Newman, Nancy S., Wilson-Costello, Deanne E., Payne, Allison, Bhola, Monika, Yalcinkaya, Gulgun, Siner, Bonnie S., Friedman, Harriet G., Roth, Elizabeth, Truog, William E., Pallotto, Eugenia K., Kilbride, Howard W., Gauldin, Cheri, Holmes, Anne, Johnson, Kathy, Knutson, Allison, Schibler, Kurt, Poindexter, Brenda B., Merhar, Stephanie, Yolton, Kimberly, Gratton, Teresa L., Grisby, Cathy, Kirker, Kristin, Wuertz, Sandra, Carlton, David P., Adams-Chapman, Ira, Hale, Ellen C., Loggins, Yvonne C., Bottcher, Diane I., Mackie, Colleen, Carter, Sheena L., LaRossa, Maureen Mulligan, Wineski, Lynn C., Smikle, Gloria V., Leon-Hernandez, Angela, Kendrick-Allwood, Salathiel, Cotten, C. Michael, Goldberg, Ronald N., Goldstein, Ricki F., Malcolm, William F., Ashley, Patricia L., Finkle, Joanne, Fisher, Kimberley A., Grimes, Sandra, Gustafson, Kathryn E., Laughon, Matthew M., Bose, Carl L., Bernhardt, Janice, Bose, Gennie, Warner, Diane, Wereszczak, Janice, Kicklighter, Stephen D., Rhodes-Ryan, Ginger, Higgins, Rosemary D., Wilson Archer, Stephanie, Sokol, Gregory M., Papile, Lu Ann, Hines, Abbey C., Herron, Dianne E., Gunn, Susan, Smiley, Lucy, Kennedy, Kathleen A., Tyson, Jon E., Arldt-McAlister, Julie, Burson, Katrina, Dempsey, Allison G., Evans, Patricia W., Garcia, Carmen, Jiminez, Margarita, John, Janice, Jones, Patrick M., Lillie, M. Layne, Martin, Karen, Martin, Sara C., McDavid, Georgia E., Rodgers, Shawna, Siddiki, Saba Khan, Sperry, Daniel, Pierce Tate, Patti L., Wright, Sharon L., Sánchez, Pablo J., Nelin, Leif D., Jadcherla, Sudarshan R., Luzader, Patricia, Fortney, Christine A., Besner, Gail E., Parikh, Nehal A., Wallace, Dennis, Gantz, Marie G., Newman, Jamie E., Auman, Jeanette O'Donnell, Crawford, Margaret, Gabrio, Jenna, Leblond, David, Petrie Huitema, Carolyn M., Zaterka-Baxter, Kristin M., Van Meurs, Krisa P., Chock, Valerie Y., Stevenson, David K., Adams, Marian M., Ball, M. Bethany, Bentley, Barbara, DeAnda, Maria Elena, Debattista, Anne M., Earhart, Beth, Huffman, Lynne C., Ismael, Magdy, Krueger, Casey E., Palmquist, Andrew W., Proud, Melinda S., Reichert, Elizabeth N., Sankar, Meera N., St. John, Nicholas H., Taylor, Heather L., Weiss, Hali E., Frantz, Ivan D., III, Fiascone, John M., MacKinnon, Brenda L., Nylen, Ellen, Furey, Anne, Sibley, Cecelia E., Brussa, Ana K., Carlo, Waldemar A., Ambalavanan, Namasivayam, Bailey, Kirstin J., Biasini, Fred J., Collins, Monica V., Cosby, Shirley S., Phillips, Vivien A., Rector, Richard V., Whitley, Sally, Devaskar, Uday, Garg, Meena, Purdy, Isabell B., Chanlaw, Teresa, Geller, Rachel, Finer, Neil N., Vaucher, Yvonne E., Kaegi, David, Rasmussen, Maynard R., Arnell, Kathy, Demetrio, Clarence, Fuller, Martha G., Rich, Wade, West, Radmila, Baack, Michelle L., Ellsbury, Dan L., Hogden, Laurie A., Klein, Jonathan M., Dagle, John M., Johnson, Karen J., Tud, Tracy L., Elenkiwich, Chelsey, Henning, Megan M., Broadbent, Megan, Schmelzel, Mendi L., Walker, Jacky R., Goeke, Claire A., Watterberg, Kristi L., Ohls, Robin K., Backstrom Lacy, Conra, Brown, Sandra, Fuller, Janell, Hartenberger, Carol, Lowe, Jean R., Sundquist Beauman, Sandra, Hanson, Mary Ruffner, Dupont, Tara, Kuan, Elizabeth, Schmidt, Barbara, Kirpalani, Haresh, Chaudhary, Aasma S., Abbasi, Soraya, Mancini, Toni, Cucinotta, Dara M., Bernbaum, Judy C., Gerdes, Marsha, Hurt, Hallam, D'Angio, Carl T., Guillet, Ronnie, Myers, Gary J., Lakshminrusimha, Satyan, Reynolds, Anne Marie, Hartley-McAndrew, Michelle E., Wadkins, Holly I.M., Sacilowski, Michael G., Reubens, Linda J., Jensen, Rosemary L., Merzbach, Joan, Zorn, William, Farooq, Osman, Maffett, Deanna, Williams, Ashley, Hunn, Julianne, Guilford, Stephanie, Yost, Kelley, Rowan, Mary, Prinzing, Diane M., Wynn, Karen, Fallone, Cait, Scorsone, Ann Marie, Wyckoff, Myra H., Brion, Luc P., Heyne, Roy J., Vasil, Diana M., Adams, Sally S., Chen, Lijun, De Leon, Maria M., Eubanks, Frances, Guzman, Alicia, Heyne, Elizabeth T., Madden, Linda A., Miller, Nancy A., Lee, Lizette E., Pavageau, Lara, Sepulveda, Pollieanna, Boatman, Cathy Twell, Faix, Roger G., Yoder, Bradley A., Baserga, Mariana, Osborne, Karen A., Baker, Shawna, Bird, Karie, Burnett, Jill, Christensen, Susan, Davis, Brandy, Elmont, Jennifer O., Jensen, Jennifer J., Loertscher, Manndi C., Marchant, Trisha, Maxson, Earl, Minton, Stephen D., Parry, D. Melody, Rau, Carrie A., Schaefer, Susan T., Sheffield, Mark J., Spencer, Cynthia, Steffen, Mike, Weaver-Lewis, Kimberlee, Winter, Sarah, Woodbury, Kathryn D., Zanetti, Karen, Shankaran, Seetha, Chawla, Sanjay, Sood, Beena G., Pappas, Athina, Natarajan, Girija, Bajaj, Monika, Bara, Rebecca, Johnson, Mary E., Goldston, Laura, Wiggins, Stephanie A., Christensen, Mary K., Carlson, Martha, Barks, John, White, Diane F., Ehrenkranz, Richard A., Jacobs, Harris, Butler, Christine G., Cervone, Patricia, Greisman, Sheila, Konstantino, Monica, Poulsen, JoAnn, Taft, Janet, Romano, Elaine, Brumbaugh, Jane E., Bell, Edward F., Grey, Scott F., DeMauro, Sara B., Vohr, Betty R., Harmon, Heidi M., Bann, Carla M., Rysavy, Matthew A., Logan, J. Wells, Colaizy, Tarah T., Peralta-Carcelen, Myriam A., McGowan, Elisabeth C., Duncan, Andrea F., Stoll, Barbara J., Das, Abhik, and Hintz, Susan R.

Published
2020
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18. Early Cumulative Supplemental Oxygen Predicts Bronchopulmonary Dysplasia in High Risk Extremely Low Gestational Age Newborns

Author

Wai, Katherine C, Kohn, Michael A, Ballard, Roberta A, Truog, William E, Black, Dennis M, Asselin, Jeanette M, Ballard, Philip L, Rogers, Elizabeth E, Keller, Roberta L, and Group, Trial of Late Surfactant Study

Subjects
Paediatrics, Biomedical and Clinical Sciences, Neonatal Respiratory Distress, Clinical Research, Pediatric, Lung, Preterm, Low Birth Weight and Health of the Newborn, Perinatal Period - Conditions Originating in Perinatal Period, Prevention, Bronchopulmonary Dysplasia, Female, Gestational Age, Humans, Infant, Extremely Low Birth Weight, Infant, Newborn, Infant, Premature, Male, Oxygen Inhalation Therapy, Prospective Studies, ROC Curve, Risk, Survival Rate, Trial of Late Surfactant (TOLSURF) Study Group, inhaled nitric oxide, mechanical ventilation, oxidative stress, prematurity, surfactant, Human Movement and Sports Sciences, Paediatrics and Reproductive Medicine, Pediatrics
Abstract

ObjectiveTo assess the prognostic accuracy of early cumulative supplemental oxygen (CSO) exposure for prediction of bronchopulmonary dysplasia (BPD) or death, and to evaluate the independent association of CSO with BPD or death.Study designWe performed a secondary analysis of the Trial of Late Surfactant, which enrolled 511 infants born at ≤28 weeks gestational age who were mechanically ventilated at 7-14 days of life. Our primary outcome was BPD or death at 36 weeks postmenstrual age, as determined by a physiological oxygen/flow challenge. Average daily supplemental oxygen (fraction of inspired oxygen - 0.21) was calculated. CSO was calculated as the sum of the average daily supplemental oxygen over time periods of interest up to 28 days of age. Area under the receiver operating curve (AUROC) values were generated to evaluate the accuracy of CSO for prediction of BPD or death. The independent relationship between CSO and BPD or death was assessed in multivariate modeling, while adjusting for mean airway pressure.ResultsIn the study infants, mean gestational age at birth was 25.2 ± 1.2 weeks and mean birth weight was 700 ± 165 g. The AUROC value for CSO at 14 days was significantly better than that at earlier time points for outcome prediction (OR, 0.70; 95% CI, 0.65-0.74); it did not increase with the addition of later data. In multivariate modeling, a CSO increase of 1 at 14 days increased the odds of BPD or death (OR, 1.7; 95% CI, 1.3-2.2; P

Published
2016

19. Randomized Trial of Late Surfactant Treatment in Ventilated Preterm Infants Receiving Inhaled Nitric Oxide

Author

Ballard, Roberta A, Keller, Roberta L, Black, Dennis M, Ballard, Philip L, Merrill, Jeffrey D, Eichenwald, Eric C, Truog, William E, Mammel, Mark C, Steinhorn, Robin H, Rogers, Elizabeth E, Ryan, Rita M, Durand, David J, Asselin, Jeanette M, Bendel, Catherine M, Bendel-Stenzel, Ellen M, Courtney, Sherry E, Dhanireddy, Ramasubbareddy, Hudak, Mark L, Koch, Frances R, Mayock, Dennis E, McKay, Victor J, O'Shea, T Michael, Porta, Nicolas F, Wadhawan, Rajan, Palermo, Lisa, Strong, S Hamilton, Immamura-Ching, J, Orfanos-Villalobos, M, Williams, C, Horton, D, Pacello, L, Willard, A, Gauldin, C, Holmes, A, Johnson, P, Meinert, K, Reynolds, AM, Lucie, J, Conway, P, Sacilowski, ML, Leadersdorff, M, Orbank, P, Wynn, K, deUngria, M, Khan, J, Hamann, K, Schau, M, Hopkins, B, Jenson, J, Garcia, C, Shariff, J, McGovern, R, Adelman, J, Combs, A, Tjersland, M, Walker, S, Howland, E, Longoria, J, Meo, H, McDavid, G, Burson, K, Hinojosa, R, Johnson, C, Miller, K, Rogers, S, Wright, S, Barnette, K, Kellum, A, Burke, M, Hayes, C, Chadwick, S, Howard, D, Kennedy, C, Prince, R, Stefanescu, B, Helderman, J, Warden, K, Brown, P, Griffin, J, Conley, L, Georgieff, M, Davern, B, Mills, M, Ritter, S, Wagner, C, Fanning, D, Roberson, J, Lampland, A, Meyers, P, Brey, A, Worwa, C, Dixon, P, Ebert, G, Hejl, C, Maxwell, M, McCullough, K, Abiad, MT El, Talati, A, Dempsey, S, and Gammage, K

Subjects
Paediatrics, Biomedical and Clinical Sciences, Preterm, Low Birth Weight and Health of the Newborn, Lung, Perinatal Period - Conditions Originating in Perinatal Period, Pediatric, Patient Safety, Neonatal Respiratory Distress, Clinical Trials and Supportive Activities, Clinical Research, Reproductive health and childbirth, Administration, Inhalation, Bronchopulmonary Dysplasia, Female, Humans, Infant, Newborn, Infant, Premature, Infant, Premature, Diseases, Infant, Very Low Birth Weight, Male, Nitric Oxide, Pulmonary Surfactants, Respiration, Artificial, Survival Rate, United States, TOLSURF Study Group, Human Movement and Sports Sciences, Paediatrics and Reproductive Medicine, Pediatrics
Abstract

ObjectiveTo assess whether late surfactant treatment in extremely low gestational age (GA) newborn infants requiring ventilation at 7-14 days, who often have surfactant deficiency and dysfunction, safely improves survival without bronchopulmonary dysplasia (BPD).Study designExtremely low GA newborn infants (GA ≤28 0/7 weeks) who required mechanical ventilation at 7-14 days were enrolled in a randomized, masked controlled trial at 25 US centers. All infants received inhaled nitric oxide and either surfactant (calfactant/Infasurf) or sham instillation every 1-3 days to a maximum of 5 doses while intubated. The primary outcome was survival at 36 weeks postmenstrual age (PMA) without BPD, as evaluated by physiological oxygen/flow reduction.ResultsA total of 511 infants were enrolled between January 2010 and September 2013. There were no differences between the treated and control groups in mean birth weight (701 ± 164 g), GA (25.2 ± 1.2 weeks), percentage born at GA

Published
2016

20. Developmental Outcomes of Extremely Preterm Infants with a Need for Child Protective Services Supervision

Author

Polin, Richard A., Laptook, Abbott R., Keszler, Martin, Hensman, Angelita M., Alksninis, Barbara, Basso, Kristin M., Burke, Robert, Caskey, Melinda, Johnson, Katharine, Keszler, Mary Lenore, Knoll, Andrea M., Leach, Theresa M., Little, Emilee, McGowan, Elisabeth C., Vieira, Elisa, Watson, Victoria E., Ventura, Suzy, Walsh, Michele C., Fanaroff, Avroy A., Hibbs, Anna Marie, Wilson-Costello, Deanne E., Newman, Nancy S., Payne, Allison H., Siner, Bonnie S., Bhola, Monika, Yalcinkaya, Gulgun, Friedman, Harriet G., Truog, William E., Pallotto, Eugenia K., Kilbride, Howard W., Gauldin, Cheri, Holmes, Anne, Johnson, Kathy, Knutson, Allison, Schibler, Kurt, Donovan, Edward F., Grisby, Cathy, Bridges, Kate, Alexander, Barbara, Fischer, Estelle E., Mincey, Holly L., Hessling, Jody, Gratton, Teresa L., Jackson, Lenora, Kirker, Kristin, Muthig, Greg, Steichen, Jean J., Tepe, Stacey, Yolton, Kimberly, Goldberg, Ronald N., Cotten, C. Michael, Goldstein, Ricki F., Ashley, Patricia L., Malcolm, William F., Auten, Kathy J., Fisher, Kimberley A., Grimes, Sandra, Gustafson, Kathryn E., Lohmeyer, Melody B., Finkle, Joanne, Laughon, Matthew M., Bose, Carl L., Bernhardt, Janice, Bose, Gennie, Clark, Cindy, Manor, Linda, Warner, Diane, Wereszczak, Janice, Carlton, David P., Stoll, Barbara J., Adams-Chapman, Ira, Hale, Ellen C., Loggins, Yvonne, Archer, Stephanie Wilson, Sokol, Gregory M., Poindexter, Brenda B., Dusick, Anna M., Papile, Lu-Ann, Gunn, Susan, Hamer, Faithe, Herron, Dianne E., Hines, Abbey C., Lytle, Carolyn, Minnich, Heike M., Smiley, Lucy, Wilson, Leslie Dawn, Sanchez, Pablo J., Nelin, Leif D., Jadcherla, Sudarshan R., Luzader, Patricia, Fortney, Christine A., Besner, Gail E., Parikh, Nehal A., Das, Abhik, Wallace, Dennis, Gantz, Marie G., Poole, W. Kenneth, Newman, Jamie E., O'Donnell Auman, Jeanette, Crawford, Margaret M., Petrie Huitema, Carolyn M., Zaterka-Baxter, Kristin M., Van Meurs, Krisa P., Stevenson, David K., Hintz, Susan R., Ball, M. Bethany, Davis, Alexis S., Palmquist, Andrew W., Proud, Melinda S., Bentley, Barbara, Bruno, Elizabeth, DeAnda, Maria Elena, DeBattista, Anne M., Earhart, Beth, Huffman, Lynne C., Kohn, Jean G., Krueger, Casey, Weiss, Hali E., Frantz, Ivan D., III, Fiascone, John M., MacKinnon, Brenda L., Furey, Anne, Nylen, Ellen, Carlo, Waldemar A., Ambalavanan, Namasivayam, Peralta-Carcelen, Myriam, Collins, Monica V., Cosby, Shirley S., Biasini, Fred J., Johnston, Kristen C., Nelson, Kathleen G., Patterson, Cryshelle S., Phillips, Vivien A., Whitley, Sally, Devaskar, Uday, Garg, Meena, Purdy, Isabell B., Chanlaw, Teresa, Geller, Rachel, Finer, Neil N., Vaucher, Yvonne E., Kaegi, David, Rasmussen, Maynard R., Arnell, Kathy, Demetrio, Clarence, Fuller, Martha G., Rich, Wade, Bell, Edward F., Colaizy, Tarah T., Acarregui, Michael J., Ellsbury, Dan L., Widness, John A., Johnson, Karen J., Campbell, Donia B., Eastman, Diane L., Walker, Jacky R., Brumbaugh, Jane E., Duara, Shahnaz, Bauer, Charles R., Everett-Thomas, Ruth, Fajardo-Hiriart, Sylvia, Rigaud, Arielle, Calejo, Maria, Frade Eguaras, Silvia M., Berkowits, Michelle Harwood, Garcia, Andrea, Pierre, Helina, Stoerger, Alexandra, Watterberg, Kristi L., Lowe, Jean R., Fuller, Janell F., Ohls, Robin K., Lacy, Conra Backstrom, Duncan, Andrea F., Montman, Rebecca, Schmidt, Barbara, Kirpalani, Haresh, DeMauro, Sara B., Chaudhary, Aasma S., Abbasi, Soraya, Mancini, Toni, Cucinotta, Dara M., Bernbaum, Judy C., Gerdes, Marsha, Hurt, Hallam, D'Angio, Carl T., Phelps, Dale L., Guillet, Ronnie, Lakshminrusimha, Satyan, Johnson, Julie Babish, Reubens, Linda J., Horihan, Cassandra A., Hust, Diane, Jensen, Rosemary L., Kushner, Emily, Merzbach, Joan, Myers, Gary J., Rowan, Mary, Wadkins, Holly I.M., Bowman, Melissa, Hunn, Julianne, Guilford, Stephanie, Maffett, Deanna, Osman, Farooq, Prinzing, Diane, Reynolds, Anne Marie, Sacilowski, Michael G., Williams, Ashley, Wynn, Karen, Yost, Kelley, Zorn, William, Zwetsch, Lauren, Kennedy, Kathleen A., Tyson, Jon E., McDavid, Georgia E., Alaniz, Nora I., Arldt-McAlister, Julie, Burson, Katrina, Evans, Patricia W., Garcia, Carmen, Green, Charles, Harris, Beverly Foley, Jiminez, Margarita, John, Janice, Jones, Patrick M., Lillie, Layne M., Lis, Anna E., Martin, Karen, Martin, Sara C., Morris, Brenda H., Poundstone, M. Layne, Robichaux, Peggy, Rodgers, Shawna, Siddiki, Saba, Simmons, Maegan C., Sperry, Daniel, Pierce Tate, Patti L., Wright, Sharon L., Wyckoff, Myra H., Brion, Luc P., Heyne, Roy J., Salhab, Walid A., Rosenfeld, Charles R., Vasil, Diana M., Chen, Lijun, Guzman, Alicia, Hensley, Gaynelle, Leps, Melissa H., Miller, Nancy A., Morgan, Janet S., Adams, Sally S., Boatman, Catherine Twell, Heyne, Elizabeth T., Madden, Linda A., Torres, Lizette E., Faix, Roger G., Yoder, Bradley A., Osborne, Karen A., Spencer, Cynthia, Weaver-Lewis, Kimberlee, Baker, Shawna, Bird, Karie, Burnett, Jill, Steffen, Michael, Jensen, Jennifer J., Winter, Sarah, Zanetti, Karen, O'Shea, T. Michael, Dillard, Robert G., Washburn, Lisa K., Jackson, Barbara G., Peters, Nancy, Chiu, Korinne, Allred, Deborah Evans, Goldstein, Donald J., Halfond, Raquel, Peterson, Carroll, Waldrep, Ellen L., Welch, Cherrie D., Morris, Melissa Whalen, Hounshell, Gail Wiley, Shankaran, Seetha, Pappas, Athina, Barks, John, Bara, Rebecca, Goldston, Laura A., Natarajan, Girija, Christensen, Mary, Wiggins, Stephanie A., White, Diane, Ehrenkranz, Richard A., Jacobs, Harris, Butler, Christine G., Cervone, Patricia, Greisman, Sheila, Konstantino, Monica, Poulsen, JoAnn, Taft, Janet, Williams, Joanne, Romano, Elaine, Laptook, Abbot. R., Lowe, Jean, Chowdhury, Dhuly, Higgins, Rosemary D., and Vohr, Betty R.

Published
2019
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21. Inhaled Nitric Oxide Increases Urinary Nitric Oxide Metabolites and Cyclic Guanosine Monophosphate in Premature Infants: Relationship to Pulmonary Outcome

Author

Ballard, Philip L, Keller, Roberta L, Black, Dennis M, Durand, David J, Merrill, Jeffrey D, Eichenwald, Eric C, Truog, William E, Mammel, Mark C, Steinhorn, Robin, Ryan, Rita M, Courtney, Sherry E, Horneman, Hart, and Ballard, Roberta A

Subjects
Paediatrics, Biomedical and Clinical Sciences, Perinatal Period - Conditions Originating in Perinatal Period, Infant Mortality, Pediatric, Preterm, Low Birth Weight and Health of the Newborn, Neonatal Respiratory Distress, Lung, Clinical Research, Respiratory, Good Health and Well Being, Administration, Inhalation, Biomarkers, Bronchopulmonary Dysplasia, Creatinine, Cyclic GMP, Dose-Response Relationship, Drug, Female, Humans, Infant, Newborn, Infant, Premature, Infant, Premature, Diseases, Male, Nitric Oxide, Regression Analysis, Respiration, Artificial, nitric oxide, cyclic GMP, bronchopulmonary dysplasia, premature, urine, Investigators of TOLSURF Pilot and TOLSURF, Clinical Sciences, Paediatrics and Reproductive Medicine, Obstetrics & Reproductive Medicine, Reproductive medicine, Midwifery
Abstract

ObjectiveInhaled nitric oxide (iNO) has been tested to prevent bronchopulmonary dysplasia (BPD) in premature infants, however, the role of cyclic guanosine monophosphate (cGMP) is not known. We hypothesized that levels of NO metabolites (NOx) and cGMP in urine, as a noninvasive source for biospecimen collection, would reflect the dose of iNO and relate to pulmonary outcome.Study designStudies were performed on 125 infants who required mechanical ventilation at 7 to 14 days and received 24 days of iNO at 20-2 ppm. A control group of 19 infants did not receive iNO.ResultsIn NO-treated infants there was a dose-dependent increase of both NOx and cGMP per creatinine (maximal 3.1- and 2-fold, respectively, at 10-20 ppm iNO) compared with off iNO. NOx and cGMP concentrations at both 2 ppm and off iNO were inversely related to severity of lung disease during the 1st month, and the NOx levels were lower in infants who died or developed BPD at term. NOx was higher in Caucasian compared with other infants at all iNO doses.ConclusionUrinary NOx and cGMP are biomarkers of endogenous NO production and lung uptake of iNO, and some levels reflect the severity of lung disease. These results support a role of the NO-cGMP pathway in lung development.

Published
2015

22. Effect of Depth and Duration of Cooling on Deaths in the NICU Among Neonates With Hypoxic Ischemic Encephalopathy: A Randomized Clinical Trial

Author

Shankaran, Seetha, Laptook, Abbot R, Pappas, Athina, McDonald, Scott A, Das, Abhik, Tyson, Jon E, Poindexter, Brenda B, Schibler, Kurt, Bell, Edward F, Heyne, Roy J, Pedroza, Claudia, Bara, Rebecca, Van Meurs, Krisa P, Grisby, Cathy, Huitema, Carolyn M Petrie, Garg, Meena, Ehrenkranz, Richard A, Shepherd, Edward G, Chalak, Lina F, Hamrick, Shannon EG, Khan, Amir M, Reynolds, Anne Marie, Laughon, Matthew M, Truog, William E, Dysart, Kevin C, Carlo, Waldemar A, Walsh, Michele C, Watterberg, Kristi L, and Higgins, Rosemary D

Subjects
Paediatrics, Biomedical and Clinical Sciences, Clinical Research, Perinatal Period - Conditions Originating in Perinatal Period, Clinical Trials and Supportive Activities, Pediatric, Infant Mortality, Reproductive health and childbirth, Acidosis, Arrhythmias, Cardiac, Developmental Disabilities, Female, Hemorrhage, Humans, Hypothermia, Induced, Hypoxia-Ischemia, Brain, Infant, Infant, Newborn, Intensive Care Units, Neonatal, Male, Survival Analysis, Temperature, Thrombosis, Time Factors, Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network, Medical and Health Sciences, General & Internal Medicine, Biomedical and clinical sciences, Health sciences
Abstract

ImportanceHypothermia at 33.5°C for 72 hours for neonatal hypoxic ischemic encephalopathy reduces death or disability to 44% to 55%; longer cooling and deeper cooling are neuroprotective in animal models.ObjectiveTo determine if longer duration cooling (120 hours), deeper cooling (32.0°C), or both are superior to cooling at 33.5°C for 72 hours in neonates who are full-term with moderate or severe hypoxic ischemic encephalopathy.Design, setting, and participantsA randomized, 2 × 2 factorial design clinical trial performed in 18 US centers in the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Neonatal Research Network between October 2010 and November 2013.InterventionsNeonates were assigned to 4 hypothermia groups; 33.5°C for 72 hours, 32.0°C for 72 hours, 33.5°C for 120 hours, and 32.0°C for 120 hours.Main outcomes and measuresThe primary outcome of death or disability at 18 to 22 months is ongoing. The independent data and safety monitoring committee paused the trial to evaluate safety (cardiac arrhythmia, persistent acidosis, major vessel thrombosis and bleeding, and death in the neonatal intensive care unit [NICU]) after the first 50 neonates were enrolled, then after every subsequent 25 neonates. The trial was closed for emerging safety profile and futility analysis after the eighth review with 364 neonates enrolled (of 726 planned). This report focuses on safety and NICU deaths by marginal comparisons of 72 hours' vs 120 hours' duration and 33.5°C depth vs 32.0°C depth (predefined secondary outcomes).ResultsThe NICU death rates were 7 of 95 neonates (7%) for the 33.5°C for 72 hours group, 13 of 90 neonates (14%) for the 32.0°C for 72 hours group, 15 of 96 neonates (16%) for the 33.5°C for 120 hours group, and 14 of 83 neonates (17%) for the 32.0°C for 120 hours group. The adjusted risk ratio (RR) for NICU deaths for the 120 hours group vs 72 hours group was 1.37 (95% CI, 0.92-2.04) and for the 32.0°C group vs 33.5°C group was 1.24 (95% CI, 0.69-2.25). Safety outcomes were similar between the 120 hours group vs 72 hours group and the 32.0°C group vs 33.5°C group, except major bleeding occurred among 1% in the 120 hours group vs 3% in the 72 hours group (RR, 0.25 [95% CI, 0.07-0.91]). Futility analysis determined that the probability of detecting a statistically significant benefit for longer cooling, deeper cooling, or both for NICU death was less than 2%.Conclusions and relevanceAmong neonates who were full-term with moderate or severe hypoxic ischemic encephalopathy, longer cooling, deeper cooling, or both compared with hypothermia at 33.5°C for 72 hours did not reduce NICU death. These results have implications for patient care and design of future trials.Trial registrationclinicaltrials.gov Identifier: NCT01192776.

Published
2014

23. Weaning of Moderately Preterm Infants from the Incubator to the Crib: A Randomized Clinical Trial

Author

Polin, Richard A., Keszler, Martin, Hensman, Angelita M., Vieira, Elisa, Hibbs, Anna Marie, Siner, Bonnie S., Truog, William E., Pallotto, Eugenia K., Kilbride, Howard W., Gauldin, Cheri, Holmes, Anne, Johnson, Kathy, Schibler, Kurt, Kallapur, Suhas G., Grisby, Cathy, Alexander, Barbara, Fischer, Estelle E., Jackson, Lenora, Kirker, Kristin, Jennings, Jennifer, Wuertz, Sandra, Muthig, Greg, Cotten, C. Michael, Goldberg, Ronald N., Roach, Theresa, Finkle, Joanne, Fisher, Kimberley A., Laughon, Matthew M., Bose, Carl L., Bernhardt, Janice, Clark, Cindy, Kicklighter, Stephen D., Rhodes-Ryan, Ginger, Hale, Ellen C., Loggins, Yvonne, Bottcher, Diane I., Archer, Stephanie Wilson, Harmon, Heidi, Herron, Dianne E., Wright-Coltart, Shirley I., Nelin, Leif D., Jadcherla, Sudarshan R., Luzader, Patricia, Gutentag, Julie, Park, Courtney, Shadd, Julie C., Sullivan, Margaret, Grothause, Jennifer L., Stein, Melanie, Clark, Erna, Sullivan, Rox Ann, Wallace, Dennis, Zaterka-Baxter, Kristin M., Crawford, Margaret, Auman, Jeanette O'Donnell, Stevenson, David K., Herfert, Lou Ann, Ball, M. Bethany, Goodlin, Gabrielle T., Proud, Melinda S., Williams, R. Jordan, Ambalavanan, Namasivayam, Collins, Monica V., Cosby, Shirley S., Chanlaw, Teresa, Geller, Rachel, Ellsbury, Dan L., Brumbaugh, Jane E., Johnson, Karen J., Campbell, Donia B., Walker, Jacky R., Watterberg, Kristi, Lacy, Conra Backstrom, Beauman, Sandy Sundquist, Hartenberger, Carol, Kirpalani, Haresh, Eichenwald, Eric C., DeMauro, Sara B., Cook, Noah, Chaudhary, Aasma S., Abbasi, Soraya, Mancini, Toni, Cucinotta, Dara, Lakshminrusimha, Satyan, Guillet, Ronnie, Scorsone, Ann Marie, Hunn, Julianne, Jensen, Rosemary, Wadkins, Holly I.M., Guilford, Stephanie, Williams, Ashley, Wyckoff, Myra, Brion, Luc P., Vasil, Diana M., Chen, Lijun, Torres, Lizette E., Pappas, Athina, Panaitescu, Bogdan, Handel, Shelley, White, Diane F., Christensen, Mary, Wiggins, Stephanie A., Shankaran, Seetha, Bell, Edward F., Laptook, Abbot R., Saha, Shampa, Newman, Nancy S., Kazzi, S. Nadya J., Barks, John, Stoll, Barbara J., Bara, Rebecca, Gabrio, Jenna, Childs, Kirsten, Das, Abhik, Higgins, Rosemary D., Carlo, Waldemar A., Sánchez, Pablo J., Carlton, David P., Pavageau, Lara, Malcolm, William F., D'Angio, Carl T., Ohls, Robin K., Poindexter, Brenda B., Sokol, Gregory M., Van Meurs, Krisa P., Colaizy, Tarah T., Khmour, Ayman, Puopolo, Karen M., Garg, Meena, and Walsh, Michele C.

Published
2019
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24. The Impact of Pulmonary Hypertension in Preterm Infants with Severe Bronchopulmonary Dysplasia through 1 Year

Author

Lagatta, Joanne M., Hysinger, Erik B., Zaniletti, Isabella, Wymore, Erica M., Vyas-Read, Shilpa, Yallapragada, Sushmita, Nelin, Leif D., Truog, William E., Padula, Michael A., Porta, Nicolas F.M., Savani, Rashmin C., Potoka, Karin P., Kawut, Steven M., DiGeronimo, Robert, Natarajan, Girija, Zhang, Huayan, Grover, Theresa R., Engle, William A., and Murthy, Karna

Published
2018
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25. “Exploring the Association of Male Sex with Adverse Outcomes in Severe Bronchopulmonary Dysplasia: A Retrospective, Multi-Center Cohort Study”

Author

Hammond, J.D., primary, Kielt, Matthew J., additional, Conroy, Sara, additional, Lingappan, Krithika, additional, Austin, Eric D., additional, Eldredge, Laurie C., additional, Truog, William E., additional, Abman, Steven H., additional, Nelin, Leif D., additional, and Cuevas Guaman, Milenka, additional

Published
2023
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26. Early-Life Outcomes in Relation to Social Determinants of Health for Children Born Extremely Preterm

Author

Brumbaugh, Jane E., primary, Vohr, Betty R., additional, Bell, Edward F., additional, Bann, Carla M., additional, Travers, Colm P., additional, McGowan, Elisabeth C., additional, Harmon, Heidi M., additional, Carlo, Waldemar A., additional, Duncan, Andrea F., additional, Hintz, Susan R., additional, Jobe, Alan H., additional, Caplan, Michael S., additional, Polin, Richard A., additional, Laptook, Abbot R., additional, Keszler, Martin, additional, Hensman, Angelita M., additional, Alksninis, Barbara, additional, Bishop, Carmena, additional, Burke, Robert T., additional, Caskey, Melinda, additional, Hoffman, Laurie, additional, Johnson, Katharine, additional, Keszler, Mary Lenore, additional, Knoll, Andrea M., additional, Lamberson, Vita, additional, Leach, Teresa M., additional, Little, Emilee, additional, Stephens, Bonnie E., additional, Vieira, Elisa, additional, St. Pierre, Lucille, additional, Ventura, Suzy, additional, Watson, Victoria E., additional, Hibbs, Anna Maria, additional, Walsh, Michele C., additional, Wilson-Costello, Deanne E., additional, Newman, Nancy S., additional, Bhola, Monika, additional, Payne, Allison H., additional, Siner, Bonnie S., additional, Yalcinkaya, Gulgun, additional, Truog, William E., additional, Pallotto, Eugenia K., additional, Kilbride, Howard W., additional, Gauldin, Cheri, additional, Holmes, Anne, additional, Johnson, Kathy, additional, Scott, Allison, additional, Parimi, Prabhu S., additional, Gaetano, Lisa, additional, Poindexter, Brenda B., additional, Schibler, Kurt, additional, Kallapur, Suhas G., additional, Donovan, Edward F., additional, Merhar, Stephanie, additional, Grisby, Cathy, additional, Yolton, Kimberly, additional, Alexander, Barbara, additional, Beiersdorfer, Traci, additional, Bridges, Kate, additional, Cahill, Tanya E., additional, Dudley, Juanita, additional, Fischer, Estelle E., additional, Gratton, Teresa L., additional, Hayes, Devan, additional, Hessling, Jody, additional, Jackson, Lenora D., additional, Kirker, Kristin, additional, Mincey, Holly L., additional, Muthig, Greg, additional, Stacey, Sara, additional, Steichen, Jean J., additional, Tepe, Stacey, additional, Thompson, Julia, additional, Wuertz, Sandra, additional, Cotten, C. Michael, additional, Goldberg, Ronald N., additional, Goldstein, Ricki F., additional, Malcolm, William F., additional, Mago-Shah, Deesha, additional, Ashley, Patricia L., additional, Finkle, Joanne, additional, Auten, Kathy J., additional, Fisher, Kimberley A., additional, Grimes, Sandra, additional, Gustafson, Kathryn E., additional, Lohmeyer, Melody B., additional, Laughon, Matthew M., additional, Bose, Carl L., additional, Bernhardt, Janice, additional, Bose, Gennie, additional, Clark, Cindy, additional, Talbert, Jennifer, additional, Warner, Diane, additional, Trembath, Andrea, additional, O'Shea, T. Michael, additional, Wereszczak, Janice, additional, Kicklighter, Stephen D., additional, Rhodes-Ryan, Ginger, additional, White, Donna, additional, Patel, Ravi M., additional, Carlton, David P., additional, Stoll, Barbara J., additional, Hale, Ellen C., additional, Loggins, Yvonne C., additional, Adams-Chapman, Ira, additional, Blackwelder, Ann, additional, Bottcher, Diane I., additional, Carter, Sheena L., additional, Kendrick-Allwood, Salathiel, additional, Laursen, Judith, additional, LaRossa, Maureen Mulligan, additional, Mackie, Colleen, additional, Sanders, Amy, additional, Seabrook, Irma, additional, Smikle, Gloria, additional, Wineski, Lynn C., additional, Higgins, Rosemary D., additional, Bremer, Andrew A., additional, Archer, Stephanie Wilson, additional, Sokol, Gregory M., additional, Dusick, Anna M., additional, Papile, Lu Ann, additional, Gunn, Susan, additional, Hamer, Faithe, additional, Herron, Dianne E., additional, Hines, Abbey C., additional, Lytle, Carolyn, additional, Miller, Lucy C., additional, Minnich, Heike M., additional, Richard, Leslie, additional, Smiley, Lucy, additional, Wilson, Leslie Dawn, additional, Tyson, Jon E., additional, Kennedy, Kathleen A., additional, Khan, Amir M., additional, Duncan, Andrea, additional, Mosquera, Ricardo, additional, Stephens, Emily K., additional, McDavid, Georgia E., additional, Alaniz, Nora I., additional, Allain, Elizabeth, additional, Arldt-McAlister, Julie, additional, Burson, Katrina, additional, Dempsey, Allison G., additional, Eason, Elizabeth, additional, Evans, Patricia W., additional, Garcia, Carmen, additional, Green, Charles, additional, Hall, Donna, additional, Harris, Beverly Foley, additional, Jiminez, Margarita, additional, John, Janice, additional, Jones, Patrick M., additional, Lillie, M. Layne, additional, Lis, Anna E., additional, Martin, Karen, additional, Martin, Sara C., additional, Mason, Carrie M., additional, McKee, Shannon, additional, Morris, Brenda H., additional, Rennie, Kimberly, additional, Rodgers, Shawna, additional, Siddiki, Saba Khan, additional, Simmons, Maegan C., additional, Sperry, Daniel, additional, Pierce Tate, Patti L., additional, Wright, Sharon L., additional, Sánchez, Pablo J., additional, Nelin, Leif D., additional, Jadcherla, Sudarshan R., additional, Slaughter, Jonathan L., additional, Yeates, Keith O., additional, Keim, Sarah, additional, Maitre, Nathalie L., additional, Timan, Christopher J., additional, Luzader, Patricia, additional, Clark, Erna, additional, Fortney, Christine A., additional, Gutentag, Julie, additional, Park, Courtney, additional, Shadd, Julie, additional, Sullivan, Margaret, additional, Stein, Melanie, additional, Nelin, Mary Ann, additional, Newton, Julia, additional, Small, Kristi, additional, Burkhardt, Stephanie, additional, Purnell, Jessica, additional, Pietruszewski, Lindsay, additional, Levengood, Katelyn, additional, Batterson, Nancy, additional, Morehead, Pamela, additional, Carey, Helen, additional, Yoseff-Salameh, Lina, additional, Sullivan, Rox Ann, additional, Hague, Cole, additional, Grothause, Jennifer, additional, Fearns, Erin, additional, Fowler, Aubrey, additional, Notestine, Jennifer, additional, Tonneman, Jill, additional, Hay, Krystal, additional, Chao, Michelle, additional, Warnimont, Kyrstin, additional, Marzec, Laura, additional, Miller, Bethany, additional, Beckford, Demi R., additional, Baugher, Hallie, additional, DeSantis, Brittany, additional, Hanlon, Cory, additional, McCool, Jacqueline, additional, Das, Abhik, additional, Gantz, Marie G., additional, Wallace, Dennis, additional, Crawford, Margaret M., additional, Gabrio, Jenna, additional, Leblond, David, additional, Newman, Jamie E., additional, Petrie Huitema, Carolyn M., additional, O'Donnell Auman, Jeanette, additional, Poole, W. Kenneth, additional, Zaterka-Baxter, Kristin M., additional, Van Meurs, Krisa P., additional, Chock, Valerie Y., additional, Stevenson, David K., additional, Adams, Marian M., additional, Ball, M. Bethany, additional, Bentley, Barbara, additional, Bruno, Elizabeth, additional, Davis, Alexis S., additional, Elena DeAnda, Maria, additional, DeBattista, Anne M., additional, Huffman, Lynne C., additional, Ismael, Magdy, additional, Kohn, Jean G., additional, Krueger, Casey, additional, Lowe, Janice, additional, Lucash, Ryan E., additional, Palmquist, Andrew W., additional, Patel, Jessica, additional, Proud, Melinda S., additional, Reichert, Elizabeth N., additional, John, Nicholas H. St., additional, Sivakumar, Dharshi, additional, Taylor, Heather L., additional, Wager, Natalie, additional, Williams, R. Jordan, additional, Weiss, Hali, additional, Frantz, Ivan D., additional, Fiascone, John M., additional, MacKinnon, Brenda L., additional, Furey, Anne, additional, Nylen, Ellen, additional, Church, Paige T., additional, Sibley, Cecelia E., additional, Brussa, Ana K., additional, Ambalavanan, Namasivayam, additional, Peralta-Carcelen, Myriam, additional, Nelson, Kathleen G., additional, Bailey, Kirstin J., additional, Biasini, Fred J., additional, Chopko, Stephanie A., additional, Collins, Monica V., additional, Cosby, Shirley S., additional, Johnston, Kristen C., additional, Moses, Mary Beth, additional, Patterson, Cryshelle S., additional, Phillips, Vivien A., additional, Preskitt, Julie, additional, Rector, Richard V., additional, Whitley, Sally, additional, Devaskar, Uday, additional, Garg, Meena, additional, Purdy, Isabell B., additional, Chanlaw, Teresa, additional, Geller, Rachel, additional, Finer, Neil N., additional, Vaucher, Yvonne E., additional, Kaegi, David, additional, Rasmussen, Maynard R., additional, Arnell, Kathy, additional, Demetrio, Clarence, additional, Fuller, Martha G., additional, Rich, Wade, additional, Colaizy, Tarah T., additional, Widness, John A., additional, Brumbaugh, Jane E., additional, Acarregui, Michael J., additional, Johnson, Karen J., additional, Eastman, Diane L., additional, Goeke, Claire A., additional, Schmelzel, Mendi L., additional, Walker, Jacky R., additional, Baack, Michelle L., additional, Hogden, Laurie A., additional, Broadbent, Megan, additional, Elenkiwich, Chelsey, additional, Henning, Megan M., additional, Van Muyden, Sarah, additional, Ellsbury, Dan L., additional, Campbell, Donia B., additional, Tud, Tracy L., additional, Duara, Shahnaz, additional, Bauer, Charles R., additional, Everett-Thomas, Ruth, additional, Fajardo-Hiriart, Sylvia, additional, Rigaud, Arielle, additional, Calejo, Maria, additional, Frade Eguaras, Silvia M., additional, Berkowits, Michelle Harwood, additional, Garcia, Andrea, additional, Pierre, Helina, additional, Stoerger, Alexandra, additional, Watterberg, Kristi L., additional, Fuller, Janell, additional, Ohls, Robin K., additional, Beauman, Sandra Sundquist, additional, Lacy, Conra Backstrom, additional, Hanson, Mary, additional, Hartenberger, Carol, additional, Kuan, Elizabeth, additional, Lowe, Jean R., additional, Thomson, Rebecca A., additional, DeMauro, Sara B., additional, Eichenwald, Eric C., additional, Schmidt, Barbara, additional, Kirpalani, Haresh, additional, Chaudhary, Aasma S., additional, Abbasi, Soraya, additional, Mancini, Toni, additional, Catts, Christine, additional, Cook, Noah, additional, Cucinotta, Dara M., additional, Bernbaum, Judy C., additional, Gerdes, Marsha, additional, Ghavam, Sarvin, additional, Hurt, Hallam, additional, Snyder, Jonathan, additional, Vangala, Saritha, additional, Ziolkowski, Kristina, additional, D'Angio, Carl T., additional, Phelps, Dale L., additional, Guillet, Ronnie, additional, Myers, Gary J., additional, Andrews-Hartley, Michelle, additional, Johnson, Julie Babish, additional, Binion, Kyle, additional, Bowman, Melissa, additional, Boylin, Elizabeth, additional, Burnell, Erica, additional, Coleman, Kelly R., additional, Fallone, Cait, additional, Farooq, Osman, additional, Hunn, Julianne, additional, Hust, Diane, additional, Jensen, Rosemary L., additional, Jones, Rachel, additional, Kachelmeyer, Jennifer, additional, Kushner, Emily, additional, Maffett, Deanna, additional, McKee, Kimberly G., additional, Merzbach, Joan, additional, Orme, Constance, additional, Prinzing, Diane, additional, Reubens, Linda J., additional, Rochez, Daisy, additional, Rowan, Mary, additional, Sabaratnam, Premini, additional, Scorsone, Ann Marie, additional, Wadkins, Holly I.M., additional, Yost, Kelley, additional, Zwetsch, Lauren, additional, Lakshminrusimha, Satyan, additional, Reynolds, Anne Marie, additional, Sacilowski, Michael G., additional, Guilford, Stephanie, additional, Li, Emily, additional, Williams, Ashley, additional, Zorn, William A., additional, Wyckoff, Myra H., additional, Brion, Luc P., additional, Salhab, Walid A., additional, Rosenfeld, Charles R., additional, Heyne, Roy J., additional, Vasil, Diana M., additional, Adams, Sally S., additional, Chen, Lijun, additional, De Leon, Maria M., additional, Eubanks, Francis, additional, Guzman, Alicia, additional, Hensley, Gaynelle, additional, Heyne, Elizabeth T., additional, Lee, Lizette E., additional, Leps, Melissa H., additional, Madden, Linda A., additional, McDougald, E. Rebecca, additional, Miller, Nancy A., additional, Morgan, Janet S., additional, Pavageau, Lara, additional, Sepulveda, Pollieanna, additional, Tolentino-Plata, Kristine, additional, Boatman, Cathy Twell, additional, Vera, Azucena, additional, Waterbury, Jillian, additional, Yoder, Bradley A., additional, Baserga, Mariana, additional, Faix, Roger G., additional, Winter, Sarah, additional, Minton, Stephen D., additional, Sheffield, Mark J., additional, Rau, Carrie A., additional, Baker, Shawna, additional, Bird, Karie, additional, Burnett, Jill, additional, Christensen, Susan, additional, Cole-Bledsoe, Laura, additional, Davis, Brandy, additional, Elmont, Jennifer O., additional, Jensen, Jennifer J., additional, Loertscher, Manndi C., additional, Jordan, Jamie, additional, Marchant, Trisha, additional, Maxson, Earl, additional, McGrath, Kandace M., additional, Osborne, Karen A., additional, Parry, D. Melody, additional, Reich, Brixen A., additional, Schaefer, Susan T., additional, Spencer, Cynthia, additional, Steffen, Michael, additional, Tice, Katherine, additional, Weaver-Lewis, Kimberlee, additional, Woodbury, Kathryn D., additional, Zanetti, Karen, additional, Dillard, Robert G., additional, Washburn, Lisa K., additional, Jackson, Barbara G., additional, Peters, Nancy, additional, Chiu, Korinne, additional, Allred, Deborah Evans, additional, Goldstein, Donald J., additional, Halfond, Raquel, additional, Peterson, Carroll, additional, Waldrep, Ellen L., additional, Welch, Cherrie D., additional, Morris, Melissa Whalen, additional, Hounshell, Gail Wiley, additional, Shankaran, Seetha, additional, Sood, Beena G., additional, Natarajan, Girija, additional, Pappas, Athina, additional, Abramczyk, Katherine, additional, Agarwal, Prashant, additional, Bajaj, Monika, additional, Bara, Rebecca, additional, Billian, Elizabeth, additional, Chawla, Sanjay, additional, Childs, Kirsten, additional, De Jesus, Lilia C., additional, Driscoll, Debra, additional, February, Melissa, additional, Goldston, Laura A., additional, Johnson, Mary E., additional, Muran, Geraldine, additional, Panaitescu, Bogdan, additional, Prentiss, Jeannette E., additional, White, Diane, additional, Woldt, Eunice, additional, Barks, John, additional, Wiggins, Stephanie A., additional, Christensen, Mary K., additional, Carlson, Martha D., additional, Ehrenkranz, Richard A., additional, Jacobs, Harris, additional, Butler, Christine G., additional, Cervone, Patricia, additional, Greisman, Sheila, additional, Konstantino, Monica, additional, Poulsen, JoAnn, additional, Taft, Janet, additional, Williams, Joanne, additional, and Romano, Elaine, additional

Published
2023
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27. Maternal Black Race and Persistent Wheezing Illness in Former Extremely Low Gestational Age Newborns: Secondary Analysis of a Randomized Trial

Author

Strong, Suzanne Hamilton, Immamura-Ching, Jill, Orfanos-Villalobos, Margaret, Williams, Cassandra, Durand, David J., Merrill, Jeffrey D., Horton, Dolia, Pacello, Loretta, Willard, April, Truog, William E., Gauldin, Cheryl, Holmes, Anne, Johnson, Patrice, Meinert, Kerrie, Reynolds, Anne Marie, Lucie, Janine, Conway, Patrick, Sacilowski, Michael, Leadersdorff, Michael, Orbank, Pam, Wynn, Karen, Steinhorn, Robin H., deUngria, Maria, Khan, Janine Yasmin, Hamann, Karin, Schau, Molly, Hopkins, Brad, Jenson, James, Garcia, Carmen, Parekh, Aruna, Shariff, Jila, McGovern, Rose, Adelman, Jeff, Combs, Adrienne, Tjersland, Mary, Mayock, Dennis E., Howland, Elizabeth, Walker, Susan, Longoria, Jim, Meo, Holly, Khan, Amir, McDavid, Georgia, Burson, Katrina, Hinojosa, Richard, Johnson, Christopher, Martin, Karen, Martin, Sarah, Rogers, Shawna, Wright, Sharon, Hudak, Mark L., Barnette, Kimberly, Kellum, Amanda, Burcke, Michelle, Hayes, Christie, Chadwick, Stephanie, Howard, Danielle, Kennedy, Carla, Prince, Renee, Helderman, Jennifer, O'Shea, T. Michael, Stefanescu, Beatrice, Warden, Kelly, Brown, Patty, Griffin, Jennifer, Conley, Laura, Bendel, Catherine M., Georgieff, Michael, Davern, Bridget, Mills, Marla, Ritter, Sharon, Wagner, Carol, Ryan, Rita M., Fanning, Deanna, Roberson, Jimmy, Mammel, Mark C., Lampland, Andrea, Meyers, Pat, Brey, Angela, Bendel-Stenzel, Ellen M., Mulrooney, Neil, Worwa, Cathy, Dixon, Pam, Ebert, Gerald, Hejl, Cathy, Maxwell, Molly, McCullough, Kristin, Dhanireddy, Ramasubbareddy, El Abiad, Mohammed T., Talati, Ajay, Dempsey, Sheila, Gammage, Kathy, Gower, Gayle, James, Kathy, LeNoue, Pam, McKay, Victor J., Bell, Suzi, Bruton, Dawn, Beaulieu, Michelle, Williams, Richard, Wadhawan, Rajan, Barron-Nelson, Robin, Taylor, Shane, Courtney, Sherry E., Sikes, Carol, Lowe, Gary, Proffitt, Betty, Rogers, Elizabeth E., Chapin, Cheryl, Horneman, Hart, Kelley, Susan, Knowles, Karin, Newton, Nancy, Vittinghoff, Eric, Hietpas, Jean, Denton, Laurie, Palermo, Lisa, Wu, Lucy, Wai, Katherine C., Hibbs, Anna M., Steurer, Martina A., Black, Dennis M., Asselin, Jeanette M., Eichenwald, Eric C., Ballard, Philip L., Ballard, Roberta A., and Keller, Roberta L.

Published
2018
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29. Outcome of Preterm Infants with Transient Cystic Periventricular Leukomalacia on Serial Cranial Imaging Up to Term Equivalent Age

Author

Jobe, Alan H., Caplan, Michael S., Polin, Richard A., Keszler, Martin, Oh, William, Vohr, Betty R., Hensman, Angelita M., Alksninis, Barbara, Basso, Kristin M., Burke, Robert, Caskey, Melinda, Johnson, Katharine, Keszler, Mary Lenore, Knoll, Andrea M., Leach, Theresa M., Little, Emilee, McGowan, Elisabeth C., Vieira, Elisa, Watson, Victoria E., Ventura, Suzy, Walsh, Michele C., Fanaroff, Avroy A., Hibbs, Anna Marie, Wilson-Costello, Deanne E., Newman, Nancy S., Payne, Allison H., Siner, Bonnie S., Bhola, Monika, Yalcinkaya, Gulgun, Friedman, Harriet G., Truog, William E., Pallotto, Eugenia K., Kilbride, Howard W., Gauldin, Cheri, Holmes, Anne, Johnson, Kathy, Knutson, Allison, Schibler, Kurt, Donovan, Edward F., Grisby, Cathy, Bridges, Kate, Alexander, Barbara, Fischer, Estelle E., Mincey, Holly L., Hessling, Jody, Gratton, Teresa L., Jackson, Lenora, Kirker, Kristin, Muthig, Greg, Steichen, Jean J., Tepe, Stacey, Mersmann, Marcia Worley, Yolton, Kimberly, Goldberg, Ronald N., Cotten, C. Michael, Goldstein, Ricki F., Ashley, Patricia L., Malcolm, William F., Auten, Kathy J., Fisher, Kimberley A., Grimes, Sandra, Gustafson, Kathryn E., Lohmeyer, Melody B., Finkle, Joanne, Laughon, Matthew M., Bose, Carl L., Bernhardt, Janice, Bose, Gennie, Warner, Diane, Wereszczak, Janice, Carlton, David P., Adams-Chapman, Ira, Hale, Ellen C., Loggins, Yvonne, Blackwelder, Ann M., Bottcher, Diane I., Mackie, Colleen, Higgins, Rosemary D., Archer, Stephanie Wilson, Sokol, Gregory M., Poindexter, Brenda B., Lemons, James A., Dusick, Anna M., Papile, Lu-Ann, Lytle, Carolyn, Hines, Abbey C., Minnich, Heike M., Herron, Dianne E., Smiley, Lucy, Gunn, Susan, Wilson, Leslie Dawn, Kennedy, Kathleen A., Tyson, Jon E., McDavid, Georgia E., Akpa, Esther G., Arldt-McAlister, Julie, Alaniz, Nora I., Burson, Katrina, Bradt, Pamela J., Dieterich, Susan, Dempsey, Allison, Duncan, Andrea F., Evans, Patricia W., Franco, Claudia I., Garcia, Carmen, Green, Charles, Harris, Beverly Foley, Jiminez, Margarita, John, Janice, Jones, Patrick M., Lillie, Layne M., Lis, Anna E., Major-Kincade, Terri, Martin, Karen, Martin, Sara C., Morris, Brenda H., Orekoya, Patricia Ann, Reddoch, Stacey, Rodgers, Shawna, Siddiki, Saba, Simmons, Maegan C., Sperry, Daniel, Tate, Patti L. Pierce, Whitely, Laura L., Wright, Sharon L., Nelin, Leif D., Jadcherla, Sudarshan R., Luzader, Patricia, Fortney, Christine A., Besner, Gail E., Parikh, Nehal A., Wallace, Dennis, Gantz, Marie G., Poole, W. Kenneth, Crawford, Margaret M., Gabrio, Jenna, Hastings, Betty K., Newman, Jamie E., O'Donnell Auman, Jeanette, Huitema, Carolyn M. Petrie, Zaterka-Baxter, Kristin M., Stevenson, David K., Ball, M. Bethany, Adams, Marian M., Davis, Alexis S., Palmquist, Andrew W., Proud, Melinda S., Bentley, Barbara, Bruno, Elizabeth, DeAnda, Maria Elena, DeBattista, Anne M., Earhart, Beth, Huffman, Lynne C., Kohn, Jean G., Krueger, Casey, Weiss, Hali E., Frantz, Ivan D., III, Fiascone, John M., MacKinnon, Brenda L., Furey, Anne, Nylen, Ellen, Peralta-Carcelen, Myriam, Collins, Monica V., Cosby, Shirley S., Biasini, Fred J., Johnston, Kristen C., Nelson, Kathleen G., Patterson, Cryshelle S., Phillips, Vivien A., Whitley, Sally, Devaskar, Uday, Garg, Meena, Purdy, Isabell B., Chanlaw, Teresa, Geller, Rachel, Finer, Neil N., Kaegi, David, Rasmussen, Maynard R., Wozniak, Paul R., Arnell, Kathy, Demetrio, Clarence, Fuller, Martha G., Henderson, Chris, Rich, Wade, Vaucher, Yvonne E., Colaizy, Tarah T., Acarregui, Michael J., Brumbaugh, Jane E., Ellsbury, Dan L., Widness, John A., Johnson, Karen J., Campbell, Donia B., Eastman, Diane L., Krutzfield, Nancy J., Duara, Shahnaz, Bauer, Charles R., Everett-Thomas, Ruth, Fajardo-Hiriart, Sylvia, Rigaud, Arielle, Calejo, Maria, Eguaras, Silvia M. Frade, Berkowits, Michelle Harwood, Garcia, Andrea, Pierre, Helina, Stoerger, Alexandra, Watterberg, Kristi L., Lowe, Jean R., Dupont, Tara, Fuller, Janell F., Ohls, Robin K., Lacy, Conra Backstrom, Montman, Rebecca, Schmidt, Barbara, Kirpalani, Haresh, DeMauro, Sara B., Chaudhary, Aasma S., Abbasi, Soraya, Mancini, Toni, Cucinotta, Dara M., Bernbaum, Judy C., Gerdes, Marsha, Hurt, Hallam, Cook, Noah, D'Angio, Carl T., Phelps, Dale L., Guillet, Ronnie, Lakshminrusimha, Satyan, Johnson, Julie Babish, Burnell, Erica, Reubens, Linda J., Horihan, Cassandra A., Jensen, Rosemary L., Kushner, Emily, Merzbach, Joan, Myers, Gary J., Rowan, Mary, Wadkins, Holly I.M., Scorsone, Anne Marie, Bowman, Melissa, Hunn, Julianne, Guilford, Stephanie, Maffett, Deanna, Farooq, Osman, Prinzing, Diane, Reynolds, Anne Marie, Sacilowski, Michael G., Williams, Ashley, Wynn, Karen, Yost, Kelley, Zorn, William, Zwetsch, Lauren, Brion, Luc P., Broyles, R. Sue, Heyne, Roy J., Ipson, Merle, Salhab, Walid A., Rosenfeld, Charles R., Vasil, Diana M., Chen, Lijun, Guzman, Alicia, Hensley, Gaynelle, Hickman, Jackie F., Leps, Melissa H., Madison, Susie, Miller, Nancy A., Morgan, Janet S., Pavageau, Lara, Adams, Sally S., Dooley, Cristin, Heyne, Elizabeth T., Lee, Lizette E., Madden, Linda A., Boatman, Catherine Twell, Faix, Roger G., Yoder, Bradley A., Osborne, Karen A., Spencer, Cynthia, Weaver-Lewis, Kimberlee, Baker, Shawna, Bird, Karie, Burnett, Jill, Steffen, Michael, Jensen, Jennifer J., Winter, Sarah, Zanetti, Karen, O'Shea, T. Michael, Dillard, Robert G., Washburn, Lisa K., Jackson, Barbara G., Peters, Nancy J., Chiu, Korinne, Allred, Deborah Evans, Goldstein, Donald J., Halfond, Raquel, Peterson, Carroll, Waldrep, Ellen L., Welch, Cherrie D., Morris, Melissa Whalen, Hounshell, Gail Wiley, Pappas, Athina, Bara, Rebecca, Goldston, Laura A., Muran, Geraldine, Natarajan, Girija, Christensen, Mary, Wiggins, Stephanie A., White, Diane, Ehrenkranz, Richard A., Jacobs, Harris, Butler, Christine G., Cervone, Patricia, Gettner, Patricia, Greisman, Sheila, Konstantino, Monica, Poulsen, JoAnn, Romano, Elaine, Taft, Janet, Williams, Joanne, Sarkar, Subrata, Shankaran, Seetha, Barks, John, Do, Barbara T., Laptook, Abbot R., Das, Abhik, Ambalavanan, Namasivayam, Van Meurs, Krisa P., Bell, Edward F., Sanchez, Pablo J., Hintz, Susan R., Wyckoff, Myra H., Stoll, Barbara J., and Carlo, Waldemar A.

Published
2018
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30. Delivery Room Resuscitation and Short-Term Outcomes in Moderately Preterm Infants

Author

Polin, Richard A., Keszler, Martin, Hensman, Angelita M., Vieira, Elisa, Hibbs, Anna Marie, Siner, Bonnie S., Truog, William E., Pallotto, Eugenia K., Kilbride, Howard W., Gauldin, Cheri, Holmes, Anne, Johnson, Kathy, Poindexter, Brenda B., Schibler, Kurt, Kallapur, Suhas G., Grisby, Cathy, Alexander, Barbara, Fischer, Estelle E., Jackson, Lenora, Kirker, Kristin, Jennings, Jennifer, Wuertz, Sandra, Muthig, Greg, Cotten, C. Michael, Goldberg, Ronald N., Finkle, Joanne, Fisher, Kimberley A., Laughon, Matthew M., Bose, Carl L., Bernhardt, Janice, Clark, Cindy, Carlton, David P., Hale, Ellen C., Loggins, Yvonne, Bottcher, Diane I., Archer, Stephanie Wilson, Sokol, Greg, Herron, Dianne E., Nelin, Leif D., Jadcherla, Sudarshan R., Luzader, Patricia, Parikh, Nehal A., Nist, Marliese Dion, Fuller, Jennifer, Gutentag, Julie, Jones, Marissa E., McGregor, Sarah, Rodgers, Elizabeth, Ulloa, Jodi A., Wolfe, Tara, Wallace, Dennis, Zaterka-Baxter, Kristin M., Crawford, Margaret, Gabrio, Jenna, Kandefer, Sarah, O'Donnell Auman, Jeanette, Stevenson, David K., Ball, M. Bethany, Proud, Melinda S., Ambalavanan, Namasivayam, Collins, Monica V., Cosby, Shirley S., Devaskar, Uday, Garg, Meena, Chanlaw, Teresa, Geller, Rachel, Colaizy, Tarah T., Ellsbury, Dan L., Brumbaugh, Jane E., Johnson, Karen J., Campbell, Donia B., Walker, Jacky R., Watterberg, Kristi L., Ohls, Robin K., Lacy, Conra Backstrom, Beauman, Sandy Sundquist, Hartenberger, Carol, Schmidt, Barbara, Kirpalani, Haresh, DeMauro, Sara B., Cook, Noah, Chaudhary, Aasma S., Abbasi, Soraya, Mancini, Toni, Cucinotta, Dara, Lakshminrusimha, Satyan, Guillet, Ronnie, Scorsone, Ann Marie, Hunn, Julianne, Jensen, Rosemary, Wadkins, Holly I.M., Guilford, Stephanie, Williams, Ashley, Brion, Luc P., Vasil, Diana M., Chen, Lijun, Torres, Lizette E., Kennedy, Kathleen A., Tyson, Jon E., Arldt-McAlister, Julie, Garcia, Carmen, Martin, Karen, McDavid, Georgia E., Wright, Sharon L., Pappas, Athina, Barks, John, Bara, Rebecca, Handel, Shelley, White, Diane F., Christensen, Mary, Wiggins, Stephanie A., Bajaj, Monika, Natarajan, Girija, Shankaran, Seetha, Wyckoff, Myra, Laptook, Abbot R., Bell, Edward F., Stoll, Barbara J., Carlo, Waldemar A., Vohr, Betty R., Saha, Shampa, Van Meurs, Krisa P., Sanchez, Pablo J., D'Angio, Carl T., Higgins, Rosemary D., Das, Abhik, Newman, Nancy, and Walsh, Michele C.

Published
2018
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31. Admission Temperature and Associated Mortality and Morbidity among Moderately and Extremely Preterm Infants

Author

Polin, Richard A., Keszler, Martin, Vohr, Betty R., Hensman, Angelita M., Vieira, Elisa, Little, Emilee, Fanaroff, Avroy A., Hibbs, Anna Marie, Newman, Nancy S., Siner, Bonnie S., Truog, William E., Pallotto, Eugenia K., Kilbride, Howard W., Gauldin, Cheri, Holmes, Anne, Johnson, Kathy, Schibler, Kurt, Kallapur, Suhas G., Grisby, Cathy, Alexander, Barbara, Fischer, Estelle E., Jackson, Lenora, Kirker, Kristin, Jennings, Jennifer, Wuertz, Sandra, Muthig, Greg, Donovan, Edward F., Hessling, Jody, Mersmann, Marcia Worley, Mincey, Holly L., Cotten, C. Michael, Goldberg, Ronald N., Finkle, Joanne, Fisher, Kimberley A., Auten, Kathy J., Laughon, Matthew M., Bose, Carl L., Bernhardt, Janice, Clark, Cindy, Stoll, Barbara J., Carlton, David P., Hale, Ellen C., Loggins, Yvonne, Bottcher, Diane I., Archer, Stephanie Wilson, Wright, Linda L., McClure, Elizabeth M., Poindexter, Brenda B., Sokol, Gregory M., Herron, Dianne E., Lemons, James A., Appel, Diana D., Miller, Lucy C., Sanchez, Pablo J., Nelin, Leif D., Jadcherla, Sudarshan R., Luzader, Patricia, Parikh, Nehal A., Nist, Marliese Dion, Fuller, Jennifer, Gutentag, Julie, Jones, Marissa E., McGregor, Sarah, Rodgers, Elizabeth, Ulloa, Jodi A., Wolfe, Tara, Das, Abhik, Wallace, Dennis, Poole, W. Kenneth, Zaterka-Baxter, Kristin M., Crawford, Margaret, Gabrio, Jenna, O'Donnell Auman, Jeanette, Huitema, Carolyn Petrie, Hastings, Betty K., Van Meurs, Krisa P., Stevenson, David K., Ball, M. Bethany, Proud, Melinda S., Carlo, Waldemar A., Ambalavanan, Namasivayam, Collins, Monica V., Cosby, Shirley S., Devaskar, Uday, Garg, Meena, Chanlaw, Teresa, Geller, Rachel, Colaizy, Tarah T., Ellsbury, Dan L., Brumbaugh, Jane E., Johnson, Karen J., Campbell, Donia B., Walker, Jacky R., Watterberg, Kristi L., Ohls, Robin K., Lacy, Conra Backstrom, Beauman, Sandra Sundquist, Hartenberger, Carol, Schmidt, Barbara, Kirpalani, Haresh, Cook, Noah, DeMauro, Sara B., Chaudhary, Aasma S., Abbasi, Soraya, Mancini, Toni, Cucinotta, Dara, D'Angio, Carl T., Guillet, Ronnie, Lakshminrusimha, Satyan, Phelps, Dale L., Reynolds, Ann Marie, Hunn, Julianne, Jensen, Rosemary, Wadkins, Holly I.M., Guilford, Stephanie, Williams, Ashley, Sacilowski, Michael, Reubens, Linda, Burnell, Erica, Rowan, Mary, Wynn, Karen, Maffett, Deanna, Brion, Luc P., Vasil, Diana M., Chen, Lijun, Torres, Lizette E., Salhab, Walid A., Madison, Susie, Hensley, Gay, Miller, Nancy A., Guzman, Alicia, Kennedy, Kathleen A., Tyson, Jon E., Arldt-McAlister, Julie, Garcia, Carmen, Martin, Karen, McDavid, Georgia E., Wright, Sharon L., Akpa, Esther G., Cluff, Patty A., Lis, Anna E., Franco, Claudia I., Pappas, Athina, Barks, John, Bara, Rebecca, Handel, Shelley, Muran, Geraldine, White, Diane F., Christensen, Mary, Wiggins, Stephanie A., Laptook, Abbot R., Bell, Edward F., Shankaran, Seetha, Boghossian, Nansi S., Wyckoff, Myra H., Kandefer, Sarah, Walsh, Michele, Saha, Shampa, and Higgins, Rosemary

Published
2018
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32. Outcomes of Preterm Infants following Discussions about Withdrawal or Withholding of Life Support

Author

Caplan, Michael S., Laptook, Abbot R., Hensman, Angelita M., Vieira, Elisa, Little, Emilee, Burke, Robert, Caskey, Melinda, Johnson, Katharine, Alksninis, Barbara, Keszler, Mary Lenore, Knoll, Andrea M., Leach, Theresa M., McGowan, Elisabeth C., Watson, Victoria E., Ventura, Suzy, Walsh, Michele C., Fanaroff, Avroy A., Hibbs, Anna Marie, Newman, Nancy S., Payne, Allison H., Wilson-Costello, Deanne E., Siner, Bonnie S., Bhola, Monika, Yalcinkaya, Gulgun, Friedman, Harriet G., Truog, William E., Pallotto, Eugenia K., Kilbride, Howard W., Gauldin, Cheri, Holmes, Anne, Johnson, Kathy, Knutson, Allison, Schibler, Kurt, Alexander, Barbara, Grisby, Cathy, Gratton, Teresa L., Steichen, Jean J., Fischer, Estelle E., Jackson, Lenora, Kirker, Kristin, Muthig, Greg, Tepe, Stacey, Yolton, Kimberly, Goldberg, Ronald N., Cotten, C. Michael, Goldstein, Ricki F., Malcolm, William F., Ashley, Patricia L., Fisher, Kimberley A., Finkle, Joanne, Gustafson, Kathryn E., Laughon, Matthew M., Bose, Carl L., Bernhardt, Janice, Bose, Gennie, Wereszczak, Janice, Carlton, David P., Hale, Ellen C., Adams-Chapman, Ira, Loggins, Yvonne, Archer, Stephanie Wilson, Sokol, Gregory M., Poindexter, Brenda B., Papile, Lu-Ann, Wilson, Leslie Dawn, Herron, Dianne E., Gunn, Susan, Smiley, Lucy, Hines, Abbey C., Nelin, Leif D., Jadcherla, Sudarshan R., Sánchez, Pablo J., Luzader, Patricia, Besner, Gail E., Parikh, Nehal A., Wallace, Dennis, Gantz, Marie G., Newman, Jamie E., O'Donnell Auman, Jeanette, Crawford, Margaret, Huitema, Carolyn M. Petrie, Zaterka-Baxter, Kristin M., Van Meurs, Krisa P., Stevenson, David K., Ball, M. Bethany, Hintz, Susan R., Proud, Melinda S., Bentley, Barbara, DeAnda, Maria Elena, DeBattista, Anne M., Earhart, Beth, Huffman, Lynne C., Krueger, Casey E., Weiss, Hali E., Carlo, Waldemar A., Ambalavanan, Namasivayam, Peralta-Carcelen, Myriam, Collins, Monica V., Cosby, Shirley S., Biasini, Fred J., Johnston, Kristen C., Patterson, Cryshelle S., Phillips, Vivien A., Whitley, Sally, Devaskar, Uday, Garg, Meena, Purdy, Isabell B., Chanlaw, Teresa, Geller, Rachel, Ellsbury, Dan L., Colaizy, Tarah T., Brumbaugh, Jane E., Widness, John A., Johnson, Karen J., Walker, Jacky R., Campbell, Donia B., Eastman, Diane L., Watterberg, Kristi L., Lowe, Jean R., Fuller, Janell F., Ohls, Robin K., Lacy, Conra Backstrom, Duncan, Andrea F., Schmidt, Barbara, Chaudhary, Aasma S., Abbasi, Soraya, Mancini, Toni, Bernbaum, Judy C., Gerdes, Marsha, Hurt, Hallam, D'Angio, Carl T., Guillet, Ronnie, Lakshminrusimha, Satyan, Reynolds, Anne Marie, Jensen, Rosemary L., Merzbach, Joan, Myers, Gary J., Williams, Ashley, Yost, Kelley, Zorn, William, Wynn, Karen, Maffett, Deanna, Prinzing, Diane, Hunn, Julianne, Guilford, Stephanie, Osman, Farooq, Rowan, Mary, Sacilowski, Michael G., Wadkins, Holly I.M., Bowman, Melissa, Kennedy, Kathleen A., Arldt-McAlister, Julie, Burson, Katrina, Duncan, Andrea Freeman, Garcia, Carmen, Harris, Beverly Foley, John, Janice, Jones, Patrick M., Lillie, Layne M., Martin, Karen, Martin, Sara C., McDavid, Georgia E., Rodgers, Shawna, Siddiki, Saba, Sperry, Daniel, Pierce Tate, Patti L., Wright, Sharon L., Wyckoff, Myra, Brion, Luc P., Vasil, Diana M., Chen, Lijun, Heyne, Roy J., Adams, Sally S., Madden, Linda A., Heyne, Elizabeth, Guzman, Alicia, Torres, Lizette E., Boatman, Catherine Twell, Pappas, Athina, Bara, Rebecca, Goldston, Laura A., Barks, John, Christensen, Mary, Wiggins, Stephanie, White, Diane, James, Jennifer, Munson, David, DeMauro, Sara B., Langer, John C., Dworetz, April R., Natarajan, Girija, Bidegain, Margarita, Fortney, Christine A., Seabrook, Ruth, Vohr, Betty R., Tyson, Jon E., Bell, Edward F., Shankaran, Seetha, Higgins, Rosemary D., Das, Abhik, Stoll, Barbara J., and Kirpalani, Haresh

Published
2017
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33. Association between Use of Prophylactic Indomethacin and the Risk for Bronchopulmonary Dysplasia in Extremely Preterm Infants

Author

Caplan, Michael S., Polin, Richard A., Laptook, Abbot R., Keszler, Martin, Hensman, Angelita M., Basso, Kristin M., Vieira, Elisa, Little, Emily, Fanaroff, Avroy A., Hibbs, Anna Marie, Newman, Nancy S., Truog, William E., Kilbride, Howard W., Pallotto, Eugenia K., Gauldin, Cheri, Holmes, Anne, Johnson, Kathy, Knutson, Allison, Schibler, Kurt, Donovan, Edward F., Alexander, Barbara, Grisby, Cathy, Hessling, Jody, Fischer, Estelle E., Jackson, Lenora D., Kirker, Kristin, Muthig, Greg, Goldberg, Ronald N., Cotten, C. Michael, Fisher, Kimberley A., Auten, Kathy J., Foy, Katherine A., Grimes, Sandra, Finkle, Joanne, Laughon, Matthew M., Bose, Carl L., Bernhardt, Janice, Bose, Gennie, Carlton, David P., Hale, Ellen C., Archer, Stephanie Wilson, Poindexter, Brenda B., Sokol, Gregory M., Wilson, Leslie Dawn, Herron, Dianne E., Sánchez, Pablo J., Nelin, Leif D., Jadcherla, Sudarshan R., Luzader, Patricia, Fortney, Christine A., Besner, Gail E., Parikh, Nehal A., Das, Abhik, Wallace, Dennis, Auman, Jeanette O'Donnell, Crawford, Margaret M., Petrie Huitema, Carolyn M., Zaterka-Baxter, Kristin M., Van Meurs, Krisa P., Adams, Marian M., Stevenson, David K., Ball, M. Bethany, Palmquist, Andrew W., Proud, Melinda S., Frantz, Ivan D., III, Fiascone, John M., MacKinnon, Brenda L., Nylen, Ellen, Carlo, Waldemar A., Ambalavanan, Namasivayam, Collins, Monica V., Cosby, Shirley S., Devaskar, Uday, Garg, Meena, Chanlaw, Teresa, Geller, Rachel, Bell, Edward F., Ellsbury, Dan L., Widness, John A., Johnson, Karen J., Campbell, Donia B., Watterberg, Kristi L., Ohls, Robin K., Lacy, Conra Backstrom, Montman, Rebecca A., Brown, Sandra, Wussow, Theresa, Hartenberger, Carol, Schmidt, Barbara, Kirpalani, Haresh, DeMauro, Sara B., Chaudhary, Aasma S., Abbasi, Soraya, Mancini, Toni, Cucinotta, Dara M., D'Angio, Carl T., Guillet, Ronnie, Lakshminrusimha, Satyan, Reynolds, Ann Marie, Reubens, Linda J., Jensen, Rosemary, Maffett, Deana, Wadkins, Holly I.M., Sacilowski, Michael G., Williams, Ashley, Guilford, Stephanie, Horihan, Cassandra A., Kennedy, Kathleen A., Tyson, Jon E., Burson, Katrina, Harris, Beverly Foley, McDavid, Georgia E., Pierce Tate, Patti L., Wright, Sharon L., Brion, Luc P., Chen, Lijun, Guzman, Alicia, Leps, Melissa H., Miller, Nancy A., Morgan, Janet S., Vasil, Diana M., Torres, Lizette E., Faix, Roger G., Yoder, Bradley A., Osborne, Karen A., Bird, Karie, Burnett, Jill, Jensen, Jennifer J., Spencer, Cynthia, Weaver-Lewis, Kimberlee, Zanetti, Karen, Shankaran, Seetha, Barks, John, Bara, Rebecca, Johnson, Mary, Christensen, Mary, Wiggins, Stephanie, Ehrenkranz, Richard A., Jacobs, Harris, Cervone, Patricia, Konstantino, Monica, Poulsen, JoAnn, Taft, Janet, Jensen, Erik A., Dysart, Kevin C., Gantz, Marie G., Carper, Benjamin, Higgins, Rosemary D., Stoll, Barbara J., and Walsh, Michele C.

Published
2017
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34. The Randomized, Controlled Trial of Late Surfactant: Effects on Respiratory Outcomes at 1-Year Corrected Age

Author

Keller, Roberta L., Eichenwald, Eric C., Hibbs, Anna Maria, Rogers, Elizabeth E., Wai, Katherine C., Black, Dennis M., Ballard, Philip L., Asselin, Jeanette M., Truog, William E., Merrill, Jeffrey D., Mammel, Mark C., Steinhorn, Robin H., Ryan, Rita M., Durand, David J., Bendel, Catherine M., Bendel-Stenzel, Ellen M., Courtney, Sherry E., Dhanireddy, Ramasubbareddy, Hudak, Mark L., Koch, Frances R., Mayock, Dennis E., McKay, Victor J., Helderman, Jennifer, Porta, Nicolas F., Wadhawan, Rajan, Palermo, Lisa, and Ballard, Roberta A.

Published
2017
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35. Interdisciplinary Care of Children with Severe Bronchopulmonary Dysplasia

Author

Abman, Steven H., Collaco, Joseph M., Shepherd, Edward G., Keszler, Martin, Cuevas-Guaman, Milenka, Welty, Stephen E., Truog, William E., McGrath-Morrow, Sharon A., Moore, Paul E., Rhein, Lawrence M., Kirpalani, Haresh, Zhang, Huayan, Gratny, Linda L., Lynch, Susan K., Curtiss, Jennifer, Stonestreet, Barbara S., McKinney, Robin L., Dysart, Kevin C., Gien, Jason, Baker, Christopher D., Donohue, Pamela K., Austin, Eric, Fike, Candice, and Nelin, Leif D.

Published
2017
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37. Randomized Trial of Late Surfactant Treatment in Ventilated Preterm Infants Receiving Inhaled Nitric Oxide

Author

Strong, S. Hamilton, Immamura-Ching, J., Orfanos-Villalobos, M., Williams, C., Horton, D., Pacello, L., Willard, A., Gauldin, C., Holmes, A., Johnson, P., Meinert, K., Reynolds, A.M., Lucie, J., Conway, P., Sacilowski, M.l., Leadersdorff, M., Orbank, P., Wynn, K., deUngria, M., Khan, J., Hamann, K., Schau, M., Hopkins, B., Jenson, J., Garcia, C., Shariff, J., McGovern, R., Adelman, J., Combs, A., Tjersland, M., Walker, S., Howland, E., Longoria, J., Meo, H., McDavid, G., Burson, K., Hinojosa, R., Johnson, C., Miller, K., Rogers, S., Wright, S., Barnette, K., Kellum, A., Burke, M., Hayes, C., Chadwick, S., Howard, D., Kennedy, C., Prince, R., Stefanescu, B., Helderman, J., Warden, K., Brown, P., Griffin, J., Conley, L., Georgieff, M., Davern, B., Mills, M., Ritter, S., Wagner, C., Fanning, D., Roberson, J., Lampland, A., Meyers, P., Brey, A., Worwa, C., Dixon, P., Ebert, G., Hejl, C., Maxwell, M., McCullough, K., El Abiad, M.T., Talati, A., Dempsey, S., Gammage, K., Gower, G., James, K., LeNoue, P., Bell, S., Bruton, D., Beaulieu, M., Williams, R., Barron-Nelson, R., Taylor, S., Sikes, N.C., Lowe, G., Proffitt, B., Chapin, C., Horneman, H., Kelley, S., Vittinghoff, E., Hietpas, J., Denton, L., Wu, L., Jobe, A., Fanaroff, A., Clemons, T., Glantz, L., Reboussin, D., Van Meurs, K., Allen, M., Vohr, B., Ballard, R., Ballard, P., Blaisdell, C., Durand, D., Black, D., Eichenwald, E., Keller, R., Mammel, M., Merrill, J., Rogers, E., Ryan, R., Truog, W., Asselin, J., Newton, N., Ballard, Roberta A., Keller, Roberta L., Black, Dennis M., Ballard, Philip L., Merrill, Jeffrey D., Eichenwald, Eric C., Truog, William E., Mammel, Mark C., Steinhorn, Robin H., Rogers, Elizabeth E., Ryan, Rita M., Durand, David J., Asselin, Jeanette M., Bendel, Catherine M., Bendel-Stenzel, Ellen M., Courtney, Sherry E., Dhanireddy, Ramasubbareddy, Hudak, Mark L., Koch, Frances R., Mayock, Dennis E., McKay, Victor J., O'Shea, T. Michael, Porta, Nicolas F., Wadhawan, Rajan, and Palermo, Lisa

Published
2016
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38. Invasive mechanical ventilation at 36 weeks post-menstrual age, adverse outcomes with a comparison of recent definitions of bronchopulmonary dysplasia

Author

Guaman, Milenka Cuevas, Pishevar, Nikou, Abman, Steven H., Keszler, Martin, Truog, William E., Panitch, Howard, and Nelin, Leif D.

Abstract

Objectives: To determine whether the need for invasive mechanical ventilation (iMV) at 36 weeks PMA in patients with severe bronchopulmonary dysplasia (sBPD) identifies those patients at highest risk for tracheostomy or gastrostomy, and to compare sBPD with recent definitions of BPD. Study design: Observational study from Jan 2015 to Sept 2019 using data from the BPD Collaborative Registry. Results: Five hundred and sixty-four patients with sBPD of whom 24% were on iMV at 36 weeks PMA. Those on iMV had significantly (p&lt; 0.0001) increased risk for tracheostomy or gastrostomy. The overall mortality rate was 3% and the risk for mortality was substantially greater in those on iMV than in those on noninvasive support at 36 weeks PMA (RR 13.8, 95% CI 4.3–44.5, p&lt; 0.0001). When applying the NICHD definition (2016) 44% had Grade III BPD. When applying the NRN definition, 6% had Grade 1 BPD, 70% had Grade 2 BPD, and 24% had Grade 3 BPD. Conclusions: Patients with sBPD who were on iMV at 36 weeks had a significantly greater risk of inhospital mortality and survivors had a significantly greater risk of undergoing tracheostomy and/or gastrostomy. The use of type 2 sBPD or Grade 3 BPD would enhance the ability to target future studies to those infants with sBPD at the highest risk of adverse long-term outcomes.

Published
2024
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39. Contributors

Author

Abbasi, Soraya, primary, Abbey, James, additional, Adzick, N. Scott, additional, Ahn, Sun-Young, additional, Albertine, Kurt H., additional, Allegaert, Karel, additional, Alper, Seth L., additional, Altit, Gabriel, additional, Altschuler, Steven M., additional, Alvaro, Ruben E., additional, Amorosa, Jennifer M.H., additional, Anbuhl, Kelsey L., additional, Andersen, Claus Yding, additional, Anderson, Richard A., additional, Askenazi, David J., additional, Auten, Richard Lambert, additional, Autmizguine, Julie, additional, Azhibekov, Timur, additional, Back, Stephen A., additional, Badaut, Jérôme, additional, Baker, Peter Russell, additional, Ballard, Philip L., additional, Bancalari, Eduardo H., additional, Barichello, Tatiana, additional, Battaglia, Frederick, additional, Baum, Michel, additional, Beggs, Simon, additional, Bell, Edward F., additional, Benchimol, Corinne, additional, Benders, Manon J.N.L., additional, Bennet, Laura, additional, Bennett, Phillip R., additional, Berger, Melvin, additional, Bernhard, Wolfgang, additional, Bertram, John F., additional, Bhosle, Vikrant K., additional, Bhutani, Vinod K., additional, Black, M. Jane, additional, Bliss, Joseph M., additional, Bolender, David L., additional, Brandenburg, Joline E., additional, Broussard, Delma L., additional, Brown, Laura Davidson, additional, Burrin, Douglas G., additional, Cannon, Barbara, additional, Caplan, Michael, additional, Carlson, Susan E., additional, Carlton, David P., additional, Caruana, Georgina, additional, Cashore, William J., additional, Chaemsaithong, Piya, additional, Chaiyasit, Noppadol, additional, Charlton, Jennifer R., additional, Cheatham, Carol L., additional, Chemtob, Sylvain, additional, Chen, Yi-Yung, additional, Chevalier, Robert L., additional, Chheda, Sadhana, additional, Childs, Andrew J., additional, Christensen, Robert D., additional, Chu, Alison, additional, Chu, David H., additional, Cilio, Maria Roberta, additional, Clark, David A., additional, Cleary-Goldman, Jane, additional, Clemente, Ethel G., additional, Clements, John A., additional, Clyman, Ronald I., additional, Cohen, Susan S., additional, Colombo, John, additional, Cowett, Richard M., additional, Crawford, Peter A., additional, Crowe, James E., additional, Cullen-McEwen, Luise A., additional, Cutfield, Wayne S., additional, D'Alton, Mary E., additional, Danzer, Enrico, additional, Delacourt, Christophe, additional, Devaskar, Sherin U., additional, Diacovo, Thomas G., additional, Docheva, Nikolina, additional, Dormans, John P., additional, Dysart, Kevin, additional, El-Khuffash, Afif, additional, Ellis, Peter James, additional, Empey, Kerry McGarr, additional, Ercal, Baris, additional, Erdős, Melinda, additional, Erickson, Robert P., additional, Fahim, Mohamed A., additional, Faksh, Arij, additional, Frank, Hans-Georg, additional, Friedlich, Philippe S., additional, Friedman, Jed, additional, Gao, Yuansheng, additional, Garland, Marianne, additional, Geddes, Donna, additional, Georgieff, Michael K., additional, Gien, Jason, additional, Giussani, Dino A., additional, Goldman, Armond S., additional, González, Efrén, additional, Good, Misty, additional, Grant, Denis M., additional, Green, Lucy R., additional, Grigoriou, Emmanouil, additional, Grimberg, Adda, additional, Gross, Ian, additional, Grunau, Ruth E., additional, Guignard, Jean-Pierre, additional, Gunn, Alistair Jan, additional, Gurtunca, Nursen, additional, Hadchouel, Alice, additional, Haddad, Gabriel G., additional, Hagberg, Henrik, additional, Hale, Thomas, additional, Hambidge, K. Michael, additional, Hammerman, Cathy, additional, Hansen, Thor Willy Ruud, additional, Hanson, Mark A., additional, Harding, Richard, additional, Harris, Mary Catherine, additional, Hartmann, Peter, additional, Hassiotou, Foteini, additional, Haugen, Guttorm, additional, Hawkes, Colin P., additional, Hay, William W., additional, Hayward, Christina E., additional, Heine, Vivi M., additional, Hellström, Ann, additional, Helmrath, Michael A., additional, Hendricks-Muñoz, Karen D., additional, Herrera, Emilio, additional, Hiatt, Michael J., additional, Hoath, Steven B., additional, Hooper, Stuart B., additional, Huang, Stephen A., additional, Iacobellli, Silvia, additional, Inder, Terrie E., additional, Iruela-Arispe, M. Luisa, additional, Jadcherla, Sudarshan R., additional, Jain, Deepak, additional, Jansson, Thomas, additional, Jefferies, John Lynn, additional, Jetton, Jennifer G., additional, Jobe, Alan H., additional, Johnson, Lois H., additional, Johnston, Richard B., additional, Jones, Rebecca Lee, additional, Jose, Pedro A., additional, Kalhan, Satish C., additional, Kallapur, Suhas G., additional, Kaplan, Michael, additional, Kaplan, Stanley, additional, Karpen, Heidi Eigenrauch, additional, Karpen, Saul J., additional, Karumanchi, S. Ananth, additional, Kaskel, Frederick J., additional, Katheria, Anup C., additional, Katz, Lorraine E. Levitt, additional, Keeney, Susan E., additional, Kern, Steven E., additional, Khanjani, Shirin, additional, Kilpatrick, Laurie E., additional, Kim, Chang-Ryul, additional, Kinsella, John P., additional, Kiserud, Torvid, additional, Koenig, Joyce M., additional, Kollmann, Tobias R., additional, Kolls, Jay K., additional, Krebs, Nancy F., additional, Kulik, Thomas J., additional, Kutikov, Jessica Katz, additional, Lakshminrusimha, Satyan, additional, Lamola, Angelo A., additional, Lasunción, Miguel Angel, additional, Lavoie, Pascal M., additional, LeBien, Tucker W., additional, Lee, Mary M., additional, Lee, Matthew K., additional, Lee, Yvonne K., additional, Leibel, Sandra, additional, Levine, Fred, additional, Levy, Ofer, additional, Liu, Yang, additional, Lobritto, Steven, additional, Loomis, Cynthia A., additional, Lopez, Colleen A., additional, MacIntyre, David A., additional, Mahe, Maxime M., additional, Maheshwari, Akhil, additional, Mankouski, Anastasiya, additional, Mantilla, Carlos B., additional, Marchant, Arnaud, additional, Margolis, Kara Gross, additional, Mariscalco, M. Michele, additional, Maródi, László, additional, Maršál, Karel, additional, Martin, Richard J., additional, Matsell, Douglas G., additional, Matthews, Dwight E., additional, McArdle, Harry J., additional, McManaman, James L., additional, McNamara, Patrick J., additional, McQuillen, Patrick S., additional, McQuinn, Tim C., additional, Mercer, Judith S., additional, Meschia, Giacomo, additional, Miller, Steven P., additional, Minoo, Parviz, additional, Monagle, Paul, additional, Mortola, Jacopo P., additional, Muglia, Louis J., additional, Munshi, Upender K., additional, Namgung, Ran, additional, Narasimhan, Sumana, additional, Nedergaard, Jan, additional, Neu, Josef, additional, Nigam, Sanjay K., additional, Nogee, Lawrence M., additional, Noori, Shahab, additional, O'Brien, Barbara M., additional, Ohls, Robin K., additional, Ortega-Senovilla, Henar, additional, O'Sullivan, Justin M., additional, Owusu, Sarah A., additional, Pal, Abhijeet, additional, Panitch, Howard B., additional, Penn, Anna A., additional, Penn, Raymond B., additional, Pernia, Cameron, additional, Philipps, Anthony F., additional, Picoraro, Joseph A., additional, Pisani, Francesco, additional, Pleasure, David, additional, Pleasure, Jeanette R., additional, Pleasure, Samuel J., additional, Pomeroy, Scott L., additional, Post, Martin, additional, Prakash, Y.S., additional, Prozialeck, Joshua D., additional, Pysher, Theodore J., additional, Quigley, Raymond, additional, Rabinovitch, Marlene, additional, Raffay, Thomas M., additional, Raj, J. Usha, additional, Ramsey, Haley, additional, Rana, Sarosh, additional, Randis, Tara Marie, additional, Ranger, Manon, additional, Ratner, Adam J., additional, Regnault, Timothy R.H., additional, Rigatto, Henrique, additional, Rintoul, Natalie E., additional, Romero, Roberto, additional, Rose, James C., additional, Rosenfeld, Charles R., additional, Ross, A. Catharine, additional, Rozycki, Henry J., additional, Ryan, Thomas D., additional, Sahni, Rakesh, additional, Sajti, Eniko, additional, Sarnat, Harvey B., additional, Satlin, Lisa M., additional, Saugstad, Ola Didrik, additional, Schierding, William, additional, Schmalstieg, Frank C., additional, Schwartz, George J., additional, Schwartz, Jeffrey, additional, Segar, Jeffrey L., additional, Selewski, David T., additional, Seri, Istvan, additional, Shaffer, Thomas H., additional, Shah, Kara N., additional, Shearer, Martin J., additional, Shojaie, Sharareh, additional, Shroyer, Noah F., additional, Sibley, Colin P., additional, Sieck, Gary C., additional, Simmons, Rebecca A., additional, Sivieri, Emidio M., additional, Smith, Francine G., additional, Smith, Lois E.H., additional, Smyth, Ian M., additional, Snarr, Brian S., additional, Snyder, Evan Y., additional, Sola-Visner, Martha, additional, Solhaug, Michael J., additional, Sperling, Mark A., additional, Srinivasan, Lakshmi, additional, Stahl, Andreas, additional, Stanley, Charles A., additional, Steinhorn, Robin H., additional, Stonestreet, Barbara S., additional, Strasburger, Janette F., additional, Styne, Dennis M., additional, Sussel, Lori, additional, Tam, Emily W.Y., additional, Tan, Libo, additional, Thornton, Claire, additional, Tollin, Daniel J., additional, Tóth, Beáta, additional, Towbin, Jeffrey A., additional, Trocle, Ashley, additional, Truog, William E., additional, Tsang, Reginald C., additional, Uhler, Kristin M., additional, Van Den Anker, John N., additional, van Goudoever, Johannes (Hans) B., additional, Vannucci, Susan J., additional, Vickers, Mark H., additional, Virgintino, Daniela, additional, Volpe, Joseph J., additional, Vora, Neeta L., additional, Vyas, Neha V., additional, Wacker-Gussmann, Annette, additional, Wallace, Megan J., additional, Walsh, Brian H., additional, Wang, Alice M., additional, Warburton, David, additional, Ward, Robert M., additional, Watterberg, Kristi L., additional, Werner, Lynne A., additional, Wershil, Barry K., additional, Wert, Susan E., additional, Wessels, Andy, additional, Whitsett, Jeffrey A., additional, Wise, Michael, additional, Wolf, Matthias T., additional, Wolfson, Marla R., additional, Wong, Hector R., additional, Wynn, James L., additional, Yeo, Lami, additional, Yip, Stephen, additional, Yoder, Bradley A, additional, Yoder, Mervin C., additional, Yoshimoto, Momoko, additional, Yuskaitis, Christopher J., additional, Zhou, Dan, additional, and Zovein, Ann, additional

Published
2017
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42. Approaches to Interdisciplinary Care for Infants with Severe Bronchopulmonary Dysplasia: A Survey of the Bronchopulmonary Dysplasia Collaborative

Author

Cristea, A. Ioana, Tracy, Michael C., Bauer, Sarah E., Guaman, Milenka Cuevas, Welty, Stephen E., Baker, Christopher D., Bhombal, Shazia, Collaco, Joseph M., Courtney, Sherry E., DiGeronimo, Robert J., Eldredge, Laurie C., Gibbs, Kathleen, Hayden, Lystra P., Keszler, Martin, Lai, Khanh, McGrath-Morrow, Sharon A., Moore, Paul E., Rose, Rebecca, Sindelar, Richard, Truog, William E., Nelin, Leif D., Abman, Steven, Cristea, A. Ioana, Tracy, Michael C., Bauer, Sarah E., Guaman, Milenka Cuevas, Welty, Stephen E., Baker, Christopher D., Bhombal, Shazia, Collaco, Joseph M., Courtney, Sherry E., DiGeronimo, Robert J., Eldredge, Laurie C., Gibbs, Kathleen, Hayden, Lystra P., Keszler, Martin, Lai, Khanh, McGrath-Morrow, Sharon A., Moore, Paul E., Rose, Rebecca, Sindelar, Richard, Truog, William E., Nelin, Leif D., and Abman, Steven

Abstract

Objective: Bronchopulmonary dysplasia (BPD) remains the most common late morbidity for extremely premature infants. Care of infants with BPD requires a longitudinal approach from the neonatal intensive care unit to ambulatory care though interdisciplinary programs. Current approaches for the development of optimal programs vary among centers. Study design: We conducted a survey of 18 academic centers that are members of the BPD Collaborative, a consortium of institutions with an established interdisciplinary BPD program. We aimed to characterize the approach, composition, and current practices of the interdisciplinary teams in inpatient and outpatient domains. Results: Variations exist among centers, including composition of the interdisciplinary team, whether the team is the primary or consult service, timing of the first team assessment of the patient, frequency and nature of rounds during the hospitalization, and the timing of ambulatory visits postdischarge. Conclusion: Further studies to assess long-term outcomes are needed to optimize interdisciplinary care of infants with severe BPD. Key points: · Care of infants with BPD requires a longitudinal approach from the NICU to ambulatory care.. · Benefits of interdisciplinary care for children have been observed in other chronic conditions.. · Current approaches for the development of optimal interdisciplinary BPD programs vary among centers..

Published
2022
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43. Effect of Therapeutic Hypothermia Initiated After 6 Hours of Age on Death or Disability Among Newborns With Hypoxic-Ischemic Encephalopathy: A Randomized Clinical Trial

Author

Laptook, Abbot R., Shankaran, Seetha, Tyson, Jon E., Munoz, Breda, Bell, Edward F., Goldberg, Ronald N., Parikh, Nehal A., Ambalavanan, Namasivayam, Pedroza, Claudia, Pappas, Athina, Das, Abhik, Chaudhary, Aasma S., Ehrenkranz, Richard A., Hensman, Angelita M., Van Meurs, Krisa P., Chalak, Lina F., Hamrick, Shannon E. G., Sokol, Gregory M., Walsh, Michele C., Poindexter, Brenda B., Faix, Roger G., Watterberg, Kristi L., Frantz, Ivan D., III, Guillet, Ronnie, Devaskar, Uday, Truog, William E., Chock, Valerie Y., Wyckoff, Myra H., McGowan, Elisabeth C., Carlton, David P., Harmon, Heidi M., Brumbaugh, Jane E., Cotten, C. Michael, Sánchez, Pablo J., Hibbs, Anna Maria, and Higgins, Rosemary D.

Published
2017
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44. Admission Temperature and Associated Mortality and Morbidity among Moderately and Extremely Preterm Infants

Author

Laptook, Abbot R., Bell, Edward F., Shankaran, Seetha, Boghossian, Nansi S., Wyckoff, Myra H., Kandefer, Sarah, Walsh, Michele, Saha, Shampa, Higgins, Rosemary, Polin, Richard A., Keszler, Martin, Vohr, Betty R., Hensman, Angelita M., Vieira, Elisa, Little, Emilee, Fanaroff, Avroy A., Hibbs, Anna Marie, Newman, Nancy S., Siner, Bonnie S., Truog, William E., Pallotto, Eugenia K., Kilbride, Howard W., Gauldin, Cheri, Holmes, Anne, Johnson, Kathy, Schibler, Kurt, Kallapur, Suhas G., Grisby, Cathy, Alexander, Barbara, Fischer, Estelle E., Jackson, Lenora, Kirker, Kristin, Jennings, Jennifer, Wuertz, Sandra, Muthig, Greg, Donovan, Edward F., Hessling, Jody, Mersmann, Marcia Worley, Mincey, Holly L., Cotten, Michael C., Goldberg, Ronald N., Finkle, Joanne, Fisher, Kimberley A., Auten, Kathy J., Laughon, Matthew M., Bose, Carl L., Bernhardt, Janice, Clark, Cindy, Stoll, Barbara J., Carlton, David P., Hale, Ellen C., Loggins, Yvonne, Bottcher, Diane I., Archer, Stephanie Wilson, Wright, Linda L., McClure, Elizabeth M., Poindexter, Brenda B., Sokol, Gregory M., Herron, Dianne E., Lemons, James A., Appel, Diana D., Miller, Lucy C., Sanchez, Pablo J., Nelin, Leif D., Jadcherla, Sudarshan R., Luzader, Patricia, Parikh, Nehal A., Nist, Marliese Dion, Fuller, Jennifer, Gutentag, Julie, Jones, Marissa E., McGregor, Sarah, Rodgers, Elizabeth, Ulloa, Jodi A., Wolfe, Tara, Das, Abhik, Wallace, Dennis, Poole, Kenneth W., Zaterka-Baxter, Kristin M., Crawford, Margaret, Gabrio, Jenna, Auman, Jeanette O’Donnell, Huitema, Carolyn Petrie, Hastings, Betty K., Van Meurs, Krisa P., Stevenson, David K., Ball, Bethany M., Proud, Melinda S., Carlo, Waldemar A., Ambalavanan, Namasivayam, Collins, Monica V., Cosby, Shirley S., Devaskar, Uday, Garg, Meena, Chanlaw, Teresa, Geller, Rachel, Colaizy, Tarah T., Ellsbury, Dan L., Brumbaugh, Jane E., Johnson, Karen J., Campbell, Donia B., Walker, Jacky R., Watterberg, Kristi L., Ohls, Robin K., Lacy, Conra Backstrom, Beauman, Sandra Sundquist, Hartenberger, Carol, Schmidt, Barbara, Kirpalani, Haresh, Cook, Noah, DeMauro, Sara B., Chaudhary, Aasma S., Abbasi, Soraya, Mancini, Toni, Cucinotta, Dara, D’Angio, Carl T., Guillet, Ronnie, Lakshminrusimha, Satyan, Phelps, Dale L., Reynolds, Ann Marie, Hunn, Julianne, Jensen, Rosemary, Wadkins, Holly I.M., Guilford, Stephanie, Williams, Ashley, Sacilowski, Michael, Reubens, Linda, Burnell, Erica, Rowan, Mary, Wynn, Karen, Maffett, Deanna, Brion, Luc P., Vasil, Diana M., Chen, Lijun, Torres, Lizette E., Salhab, Walid A., Madison, Susie, Hensley, Gay, Miller, Nancy A., Guzman, Alicia, Kennedy, Kathleen A., Tyson, Jon E., Arldt-McAlister, Julie, Garcia, Carmen, Martin, Karen, McDavid, Georgia E., Wright, Sharon L., Akpa, Esther G., Cluff, Patty A., Lis, Anna E., Franco, Claudia I., Pappas, Athina, Barks, John, Bara, Rebecca, Handel, Shelley, Muran, Geraldine, White, Diane F., Christensen, Mary, and Wiggins, Stephanie A.

Published
2018
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45. Hydrocortisone to Improve Survival without Bronchopulmonary Dysplasia

Author

Watterberg, Kristi L., primary, Walsh, Michele C., additional, Li, Lei, additional, Chawla, Sanjay, additional, D’Angio, Carl T., additional, Goldberg, Ronald N., additional, Hintz, Susan R., additional, Laughon, Matthew M., additional, Yoder, Bradley A., additional, Kennedy, Kathleen A., additional, McDavid, Georgia E., additional, Backstrom-Lacy, Conra, additional, Das, Abhik, additional, Crawford, Margaret M., additional, Keszler, Martin, additional, Sokol, Gregory M., additional, Poindexter, Brenda B., additional, Ambalavanan, Namasivayam, additional, Hibbs, Anna Maria, additional, Truog, William E., additional, Schmidt, Barbara, additional, Wyckoff, Myra H., additional, Khan, Amir M., additional, Garg, Meena, additional, Chess, Patricia R., additional, Reynolds, Anne M., additional, Moallem, Mohannad, additional, Bell, Edward F., additional, Meyer, Lauritz R., additional, Patel, Ravi M., additional, Van Meurs, Krisa P., additional, Cotten, C. Michael, additional, McGowan, Elisabeth C., additional, Hines, Abbey C., additional, Merhar, Stephanie, additional, Peralta-Carcelen, Myriam, additional, Wilson-Costello, Deanne E., additional, Kilbride, Howard W., additional, DeMauro, Sara B., additional, Heyne, Roy J., additional, Mosquera, Ricardo A., additional, Natarajan, Girija, additional, Purdy, Isabell B., additional, Lowe, Jean R., additional, Maitre, Nathalie L., additional, Harmon, Heidi M., additional, Hogden, Laurie A., additional, Adams-Chapman, Ira, additional, Winter, Sarah, additional, Malcolm, William F., additional, and Higgins, Rosemary D., additional

Published
2022
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46. Outcomes of Preterm Infants following Discussions about Withdrawal or Withholding of Life Support

Author

James, Jennifer, Munson, David, DeMauro, Sara B., Langer, John C., Dworetz, April R., Natarajan, Girija, Bidegain, Margarita, Fortney, Christine A., Seabrook, Ruth, Vohr, Betty R., Tyson, Jon E., Bell, Edward F., Poindexter, Brenda B., Shankaran, Seetha, Higgins, Rosemary D., Das, Abhik, Stoll, Barbara J., Kirpalani, Haresh, Caplan, Michael S., Laptook, Abbot R., Hensman, Angelita M., Vieira, Elisa, Little, Emilee, Burke, Robert, Caskey, Melinda, Johnson, Katharine, Alksninis, Barbara, Keszler, Mary Lenore, Knoll, Andrea M., Leach, Theresa M., McGowan, Elisabeth C., Watson, Victoria E., Ventura, Suzy, Walsh, Michele C., Fanaroff, Avroy A., Hibbs, Anna Marie, Newman, Nancy S., Payne, Allison H., Wilson-Costello, Deanne E., Siner, Bonnie S., Bhola, Monika, Yalcinkaya, Gulgun, Friedman, Harriet G., Truog, William E., Pallotto, Eugenia K., Kilbride, Howard W., Gauldin, Cheri, Holmes, Anne, Johnson, Kathy, Knutson, Allison, Schibler, Kurt, Alexander, Barbara, Grisby, Cathy, Gratton, Teresa L., Steichen, Jean J., Fischer, Estelle E., Jackson, Lenora, Kirker, Kristin, Muthig, Greg, Tepe, Stacey, Yolton, Kimberly, Goldberg, Ronald N., Cotten, Michael C., Goldstein, Ricki F., Malcolm, William F., Ashley, Patricia L., Fisher, Kimberley A., Finkle, Joanne, Gustafson, Kathryn E., Laughon, Matthew M., Bose, Carl L., Bernhardt, Janice, Bose, Gennie, Wereszczak, Janice, Carlton, David P., Hale, Ellen C., Adams-Chapman, Ira, Loggins, Yvonne, Archer, Stephanie Wilson, Sokol, Gregory M., Papile, Lu-Ann, Wilson, Leslie Dawn, Herron, Dianne E., Gunn, Susan, Smiley, Lucy, Hines, Abbey C., Nelin, Leif D., Jadcherla, Sudarshan R., Sánchez, Pablo J., Luzader, Patricia, Besner, Gail E., Parikh, Nehal A., Wallace, Dennis, Gantz, Marie G., Newman, Jamie E., Auman, Jeanette OʼDonnell, Crawford, Margaret, Huitema, Carolyn Petrie M., Zaterka-Baxter, Kristin M., Van Meurs, Krisa P., Stevenson, David K., Ball, Bethany M., Hintz, Susan R., Proud, Melinda S., Bentley, Barbara, DeAnda, Maria Elena, DeBattista, Anne M., Earhart, Beth, Huffman, Lynne C., Krueger, Casey E., Weiss, Hali E., Carlo, Waldemar A., Ambalavanan, Namasivayam, Peralta-Carcelen, Myriam, Collins, Monica V., Cosby, Shirley S., Biasini, Fred J., Johnston, Kristen C., Patterson, Cryshelle S., Phillips, Vivien A., Whitley, Sally, Devaskar, Uday, Garg, Meena, Purdy, Isabell B., Chanlaw, Teresa, Geller, Rachel, Ellsbury, Dan L., Colaizy, Tarah T., Brumbaugh, Jane E., Widness, John A., Johnson, Karen J., Walker, Jacky R., Campbell, Donia B., Eastman, Diane L., Watterberg, Kristi L., Lowe, Jean R., Fuller, Janell F., Ohls, Robin K., Lacy, Conra Backstrom, Duncan, Andrea F., Schmidt, Barbara, Chaudhary, Aasma S., Abbasi, Soraya, Mancini, Toni, Bernbaum, Judy C., Gerdes, Marsha, Hurt, Hallam, DʼAngio, Carl T., Guillet, Ronnie, Lakshminrusimha, Satyan, Reynolds, Anne Marie, Jensen, Rosemary L., Merzbach, Joan, Myers, Gary J., Williams, Ashley, Yost, Kelley, Zorn, William, Wynn, Karen, Maffett, Deanna, Prinzing, Diane, Hunn, Julianne, Guilford, Stephanie, Osman, Farooq, Rowan, Mary, Sacilowski, Michael G., Wadkins, Holly I.M., Bowman, Melissa, Kennedy, Kathleen A., Arldt-McAlister, Julie, Burson, Katrina, Duncan, Andrea Freeman, Garcia, Carmen, Harris, Beverly Foley, John, Janice, Jones, Patrick M., Lillie, Layne M., Martin, Karen, Martin, Sara C., McDavid, Georgia E., Rodgers, Shawna, Siddiki, Saba, Sperry, Daniel, Tate, Patti Pierce L., Wright, Sharon L., Wyckoff, Myra, Brion, Luc P., Vasil, Diana M., Chen, Lijun, Heyne, Roy J., Adams, Sally S., Madden, Linda A., Heyne, Elizabeth, Guzman, Alicia, Torres, Lizette E., Boatman, Catherine Twell, Pappas, Athina, Bara, Rebecca, Goldston, Laura A., Barks, John, Christensen, Mary, Wiggins, Stephanie, and White, Diane

Published
2017
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50. Contributors

Author

Abman, Steven H., Ali, Noorjahan, Allegaert, Karel, Anderson, Jamie E., Ansah, Deidra A., Arya, Bhawna, Askenazi, David, Aucott, Susan W., Back, Stephen A., Baer, Gerri R., Baldwin, H. Scott, Ballas, Jerasimos, Batra, Maneesh, Bayart, Cheryl, Bellus, Gary A., Benjamin, John T., Berry, Gerard T., Billimoria, Zeenia C., Binenbaum, Gil, Blessing, Matthew S., Boos, Markus D., Bosse, Brad, Bouchard, Maryse L., Brandling-Bennett, Heather A., Brown, Colleen, Brown, Erin G., Campbell, Katherine H., Carlberg, Katie, Carter, Brian S., Chabra, Shilpi, Chang, Irene J., Cheng, Edith Y., Chiang, Kai-wen, Christensen, Robert D., Chun, Terrence, Clyman, Ronald I., Cortezzo, Donna, Maria E., Cotten, C.M., Courtney, Sherry E., Davis, Jonathan M., de Alba Campomanes, Alejandra G., Dean, Benjamin, Dees, Ellen, De, Mauro, Sara B., Denne, Scott C., Deschmann, Emöke, Di Blasi, Carolina Cecilia, Di, Vall, Sara A., Doherty, Dan, Durand, David J., Dyess, Nicolle Fernández, Eichenwald, Eric C., Eitel, Kelsey B., Engen, Rachel M., Evans, Kelly N., Farmer, Diana L., Fay, Emily, Fechner, Patricia Y., Fleishman, Rachel, Fleiss, Bobbi, Flynn, Joseph, Jr., Flynn-O’Brien, Katherine T., Kyle Fulton, G., Gallagher, Renata C., Gauda, Estelle B., Christopher Golden, W., Gontasz, Michelle M., Estévez, Natasha González, Gospe, Sidney M., Jr., Gressens, Pierre, Gupta, Deepti, Hingorani, Sangeeta, Hinson, Ashley P., Hintz, Susan R., Alan Hodson, W., Hoppe, Kara K., Huang, Alyssa, Huang, Benjamin, Huen, Kathy, Huff, Katie A., Ionita, Cristian, Craig Jackson, J., Jackson, Jordan E., Jaksic, Tom, Javid, Patrick J., Johnson, Julia, Josephson, Cassandra D., Jungheim, Emily S., Juul, Sandra E., Kabbany, Mohammad Nasser, Karpen, Heidi, Keefe, Gregory, Keene, Jennifer C., Keiser, Amaris M., Keller, Roberta L., Kelly, Thomas F., Khorsand, Kate, Kim, Grace, Kinsella, John P., Komorowski, Allison S., Koves, Ildiko H., Lagatta, Joanne M., Lakshminrusimha, Satyan, Lam, Christina, Lantos, John D., Law, Janessa B., Lee, Su Yeon, Levy, Ofer, Lewis, David B., Lin, Philana Ling, Lorch, Scott A., Lucas, Tiffany L., Maheshwari, Akhil, Maltepe, Emin, Mandell, Erica, Manimtim, Winston M., Martin, Richard J., Mayock, Dennis E., Mc, Aleer, Irene, McQuillen, Patrick, Melvin, Ann J., Merguerian, Paul A., Merjaneh, Lina, Lawrence Merritt, J., Mezger, Valerie, Michaels, Marian G., Mietzsch, Ulrike, Miller, Steven P., Moore, Thomas R., Murray, Karen F., Nandi-Munshi, Debika, Natarajan, Niranjana, Ness, Kathryn D., Neu, Josef, Noori, Shahab, O’Shea, Thomas Michael, Jr., Oatts, Julius T., Paneth, Nigel, Parker, Thomas A., Patel, Ravi Mangal, Patel, Simran, Penn, Anna A., Pettker, Christian M., Peyvandi, Shabnam, Pihoker, Catherine, Plosa, Erin, Poindexter, Brenda, Posencheg, Michael A., Puia-Dumitrescu, Mihai, Cardona, Vilmaris Quiñones, Rice-Townsend, Samuel E., Riddle, Art, Robbins, Elizabeth, Rollins, Mark D., Rosen, Mark A., Rowe, Courtney K., Sahai, Inderneel, Saitta, Sulagna C., Salehi, Parisa, Sanchez, Pablo J., Sawyer, Taylor, Saxonhouse, Matthew A., Schroeder, Katherine M., Selewski, David T., Niroshi Senaratne, T., Seri, Istvan, Sharpe, Emily E., Sheppard, Sarah E., Shnorhavorian, Margarett, Sidbury, Robert, Simmons, La, Vone, Simmons, Rebecca A., Singh, Rachana, Sola-Visner, Martha C., Srinivasan, Lakshmi, Steflik, Heidi J., Steinhorn, Robin H., Stokes, Caleb, Stolp, Helen, Sucre, Jennifer, Sun, Angela, Taha, Dalal K., Tenney, Jessica, Thomas, Janet A., Tiller, George E., Torres, Benjamin A., Truog, William E., Upadhyay, Kirtikumar, Valentine, Gregory C., van den Anker, John N., Vohr, Betty, Wallen, Linda D., Wang, Peter (Zhan Tao), Warady, Bradley A., Ward, Robert M., Watchko, Jon F., Wehbi, Elias, Weitkamp, Joern-Hendrik, Werny, David, White, Klane K., Taylor Wild, K., Wiley, Susan, Willig, Laurel, Woodward, George A., Wright, Clyde J., Yonekawa, Karyn, Yu, Elizabeth, and Zackai, Elaine H.

Published
2024
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