5 results on '"TRILEAFLET"'
Search Results
2. Possible Early Generation of Physiological Helical Flow Could Benefit the Triflo Trileaflet Heart Valve Prosthesis Compared to Bileaflet Valves.
- Author
-
Bruecker, Ch. and Qianhui Li
- Subjects
- *
PROSTHETIC heart valves , *MECHANICAL hearts , *BIOPROSTHESIS , *PARTICLE image velocimetry , *VALVES , *AXIAL flow , *THORACIC aorta - Abstract
Background—Physiological helical flow in the ascending aorta has been well documented in the last two decades, accompanied by discussions on possible physiological benefits of such axial swirl. Recent 4D-MRI studies on healthy volunteers have found indications of early generation of helical flow, early in the systole and close to the valve plane. Objectives—Firstly, the aim of the study is to investigate the hypothesis of premature swirl existence in the ventricular outflow tract leading to helical flow in the valve plane, and second to investigate the possible impact of two different mechanical valve designs on the preservation of this early helical flow and its subsequent hemodynamic consequences. Methods—We use a pulse duplicator with an aortic arch and High-Speed Particle Image Velocimetry to document the flow evolution in the systolic cycle. The pulse-duplicator is modified with a swirl-generating insert to generate early helical flow in the valve plane. Special focus is paid to the interaction of such helical flow with different designs of mechanical prosthetic heart valves, comparing a classical bileaflet mechanical heart valve, the St. Jude Medical Regent valve (SJM Regent BMHV), with the Triflo trileaflet mechanical heart valve T2B version (Triflo TMHV). Results—When the swirl-generator is inserted, a vortex is generated in the core flow, demonstrating early helical flow in the valve plane, similar to the observations reported in the recent 4D-MRI study taken for comparison. For the Triflo trileaflet valve, the early helical flow is not obstructed in the central orifice, similar as in the case of the natural valve. Conservation of angular momentum leads to radial expansion of the core flow and flattening of the axial flow profile downstream in the arch. Furthermore, the early helical flow helps to overcome separation at the outer and inner curvature. In contrast, the two parallel leaflets for the bileaflet valve impose a flow straightener effect, annihilating the angular momentum, which has a negative impact on kinetic energy of the flow. Conclusion—The results imply better hemodynamics for the Triflo trileaflet valve based on hydrodynamic arguments under the discussed hypothesis. In addition, it makes the Triflo valve a better candidate for valve replacements in patients with a pathological generation of nonaxial velocity in the ventricle outflow tract. [ABSTRACT FROM AUTHOR]
- Published
- 2020
- Full Text
- View/download PDF
3. Possible Early Generation of Physiological Helical Flow Could Benefit the Triflo Trileaflet Heart Valve Prosthesis Compared to Bileaflet Valves
- Author
-
Ch. Bruecker and Qianhui Li
- Subjects
physiological helical flow ,mechanical heart valve prostheses ,aorta ,PIV ,trileaflet ,Technology ,Biology (General) ,QH301-705.5 - Abstract
Background—Physiological helical flow in the ascending aorta has been well documented in the last two decades, accompanied by discussions on possible physiological benefits of such axial swirl. Recent 4D-MRI studies on healthy volunteers have found indications of early generation of helical flow, early in the systole and close to the valve plane. Objectives—Firstly, the aim of the study is to investigate the hypothesis of premature swirl existence in the ventricular outflow tract leading to helical flow in the valve plane, and second to investigate the possible impact of two different mechanical valve designs on the preservation of this early helical flow and its subsequent hemodynamic consequences. Methods—We use a pulse duplicator with an aortic arch and High-Speed Particle Image Velocimetry to document the flow evolution in the systolic cycle. The pulse-duplicator is modified with a swirl-generating insert to generate early helical flow in the valve plane. Special focus is paid to the interaction of such helical flow with different designs of mechanical prosthetic heart valves, comparing a classical bileaflet mechanical heart valve, the St. Jude Medical Regent valve (SJM Regent BMHV), with the Triflo trileaflet mechanical heart valve T2B version (Triflo TMHV). Results—When the swirl-generator is inserted, a vortex is generated in the core flow, demonstrating early helical flow in the valve plane, similar to the observations reported in the recent 4D-MRI study taken for comparison. For the Triflo trileaflet valve, the early helical flow is not obstructed in the central orifice, similar as in the case of the natural valve. Conservation of angular momentum leads to radial expansion of the core flow and flattening of the axial flow profile downstream in the arch. Furthermore, the early helical flow helps to overcome separation at the outer and inner curvature. In contrast, the two parallel leaflets for the bileaflet valve impose a flow straightener effect, annihilating the angular momentum, which has a negative impact on kinetic energy of the flow. Conclusion—The results imply better hemodynamics for the Triflo trileaflet valve based on hydrodynamic arguments under the discussed hypothesis. In addition, it makes the Triflo valve a better candidate for valve replacements in patients with a pathological generation of nonaxial velocity in the ventricle outflow tract.
- Published
- 2020
- Full Text
- View/download PDF
4. Non-physiologic closing of bi-leaflet mechanical heart prostheses requires a new tri-leaflet valve design
- Author
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Gilles D. Dreyfus, Didier Lapeyre, Bart Meuris, Thierry Carrel, Bernhard Vennemann, Bas A.J.M. de Mol, Walter P. Dembitsky, Dominik Obrist, and Hartzell V. Schaff
- Subjects
medicine.medical_specialty ,Cardiac & Cardiovascular Systems ,Design ,FLOW ,610 Medicine & health ,030204 cardiovascular system & hematology ,Prosthesis Design ,Cardiac valve ,Thrombosis ,Anticoagulation ,Mechanical heart-valve ,Unmet needs ,Mechanical heart ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,medicine ,Humans ,030212 general & internal medicine ,Platelet activation ,Science & Technology ,Leaflet (botany) ,business.industry ,Hemodynamics ,Models, Cardiovascular ,Forward flow ,Flow (mathematics) ,Heart Valve Prosthesis ,Cardiovascular System & Cardiology ,Cardiology ,TRILEAFLET ,SHEAR ,Stress, Mechanical ,Rheology ,Cardiology and Cardiovascular Medicine ,business ,Life Sciences & Biomedicine - Abstract
Mechanical heart valve prostheses are based on older designs without changes during the last 40 years. Today, there is an unmet need for less thrombogenic mechanical prostheses. Analysis of the relationship between flow characteristics and thromboembolic complications is possible using numerical and biomolecular flow studies that have shown that the reverse rather than the forward flow is responsible for local platelet activation and thrombosis. After peak flow, leaflets experience flow deceleration and the leaflets are still widely open when the flow becomes zero. The closure of the valve starts with the onset of reverse flow. Therefore, the valve closes extremely fast with most of the leaflet traveling angle occurring in, International Journal of Cardiology, 304, ISSN:0167-5273
- Published
- 2020
- Full Text
- View/download PDF
5. Possible Early Generation of Physiological Helical Flow Could Benefit the Triflo Trileaflet Heart Valve Prosthesis Compared to Bileaflet Valves
- Author
-
Qianhui Li and Ch. Bruecker
- Subjects
Aortic arch ,Materials science ,TL ,0206 medical engineering ,Bioengineering ,mechanical heart valve prostheses ,02 engineering and technology ,030204 cardiovascular system & hematology ,lcsh:Technology ,Article ,03 medical and health sciences ,0302 clinical medicine ,medicine.artery ,Ascending aorta ,medicine ,biochemistry ,Ventricular outflow tract ,Systole ,lcsh:QH301-705.5 ,QC ,physiological helical flow ,QM ,trileaflet ,lcsh:T ,Mechanics ,020601 biomedical engineering ,PIV ,aorta ,Axial compressor ,lcsh:Biology (General) ,Particle image velocimetry ,Flow (mathematics) ,Body orifice ,RC - Abstract
Background&mdash, Physiological helical flow in the ascending aorta has been well documented in the last two decades, accompanied by discussions on possible physiological benefits of such axial swirl. Recent 4D-MRI studies on healthy volunteers have found indications of early generation of helical flow, early in the systole and close to the valve plane. Objectives&mdash, Firstly, the aim of the study is to investigate the hypothesis of premature swirl existence in the ventricular outflow tract leading to helical flow in the valve plane, and second to investigate the possible impact of two different mechanical valve designs on the preservation of this early helical flow and its subsequent hemodynamic consequences. Methods&mdash, We use a pulse duplicator with an aortic arch and High-Speed Particle Image Velocimetry to document the flow evolution in the systolic cycle. The pulse-duplicator is modified with a swirl-generating insert to generate early helical flow in the valve plane. Special focus is paid to the interaction of such helical flow with different designs of mechanical prosthetic heart valves, comparing a classical bileaflet mechanical heart valve, the St. Jude Medical Regent valve (SJM Regent BMHV), with the Triflo trileaflet mechanical heart valve T2B version (Triflo TMHV). Results&mdash, When the swirl-generator is inserted, a vortex is generated in the core flow, demonstrating early helical flow in the valve plane, similar to the observations reported in the recent 4D-MRI study taken for comparison. For the Triflo trileaflet valve, the early helical flow is not obstructed in the central orifice, similar as in the case of the natural valve. Conservation of angular momentum leads to radial expansion of the core flow and flattening of the axial flow profile downstream in the arch. Furthermore, the early helical flow helps to overcome separation at the outer and inner curvature. In contrast, the two parallel leaflets for the bileaflet valve impose a flow straightener effect, annihilating the angular momentum, which has a negative impact on kinetic energy of the flow. Conclusion&mdash, The results imply better hemodynamics for the Triflo trileaflet valve based on hydrodynamic arguments under the discussed hypothesis. In addition, it makes the Triflo valve a better candidate for valve replacements in patients with a pathological generation of nonaxial velocity in the ventricle outflow tract.
- Published
- 2020
- Full Text
- View/download PDF
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