1. An Integrated Quasi-Elastic Light-Scattering, Pulse-Gradient-Spin−Echo Study on the Transport Properties of α,α-Trehalose, Sucrose, and Maltose Deuterium Oxide Solutions
- Author
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Luciano Galantini, E. Tettamanti, Emilia Iannilli and, and Salvatore Magazù
- Subjects
DYNAMICS ,TREHALOSE AQUEOUS-SOLUTIONS ,Chromatography ,PROTEINS ,Chemistry ,TREHALOSE AQUEOUS-SOLUTIONS, SELF-DIFFUSION, HYDRATION, WATER, SIMULATION, DYNAMICS, PROTEINS ,HYDRATION ,Dispersity ,Analytical chemistry ,Disaccharide ,Hard spheres ,Maltose ,Trehalose ,Surfaces, Coatings and Films ,Dilution ,chemistry.chemical_compound ,Deuterium ,SELF-DIFFUSION ,SIMULATION ,Materials Chemistry ,Spin echo ,WATER ,Physical and Theoretical Chemistry - Abstract
A study on D2O solutions of trehalose, maltose, and sucrose have been performed by using quasi-elastic light-scattering (QELS) and 1H and 2H pulse-gradient-spin−echo NMR (PGSE-NMR). The self-diffusion coefficient of disaccharide (D) and the apparent diffusion coefficient Dapp have been obtained as a function of disaccharide weight fraction c and temperature (20−60 °C). Hydrodynamic radii at infinite dilution have been evaluated. In case of trehalose and sucrose a model of monodisperse hard spheres has been used to interpret the concentration dependence of D and Dapp in the dilute region (c ≤ 0.1), thus obtaining the values of the hydrodynamic radii together with the diffusing particles volume fractions as a function of c and T. The invariance of the hydrodynamic radii and the agreement with the model suggest that T and c neither induce self-aggregation of the sugars nor affect sensitively their structure and hydration. The self-diffusion coefficient of D2O (Ds) at 20 °C has also been measured for the D2O ...
- Published
- 2001
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