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5. Stability evaluation of interdigitated liposomes prepared with a combination of 1,2-distearoyl-sn-glycero-3-phosphocholine and 1,2-dilauroyl-sn-glycero-3-phosphocholine

Author

Adrar, Nabil, BAHADORİ, FATEMEH, Ceylan, Fatma Duygu, TOPÇU, GÜLAÇTI, Bedjou, Fatiha, Çapanoğlu Güven, Esra, and TOPÇU, GÜLAÇTI

Subjects
Adrar N., BAHADORİ F., Ceylan F. D. , TOPÇU G., Bedjou F., Çapanoğlu Güven E., -Stability evaluation of interdigitated liposomes prepared with a combination of 1,2-distearoyl-sn-glycero-3-phosphocholine and 1,2-dilauroyl-sn-glycero-3-phosphocholine-, JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, 2021
Abstract

BACKGROUND In order to obtain small and homogenous liposomes encapsulating gallic acid (GA) with interdigitated leaflets, a combination of phosphatidylcholine (PC) of medium length sn-1 and sn-2 acyl chains with PC of longer acyl chains at both sn1 and sn2 positions were employed. Four formulations respectively consisting of 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC); DSPC/1,2-dilauroyl-sn-glycero-3-phosphocholine (DSPC/DLPC) (1:1, mol mol(-1)); DSPC/DLPC (3:1, mol mol(-1)) and Lipoid S75, were prepared. For each formulation, the stability of liposomes during storage was investigated.

Published
2021

7. Aromaterapi

Author

TOPÇU, GÜLAÇTI, ALİM TORAMAN, GÜLBAHAR ÖZGE, and TOPÇU, GÜLAÇTI

Subjects
TOPÇU G., ALİM TORAMAN G. Ö. , Uçucu Yağların Kimyasal Bileşimi, -Aromaterapi-, ALTINTAŞ Ayten, KARTAL Murat, Editör, Türkiye Klinikleri Yayınevi, Ankara, ss.13-25, 2021
Published
2021

8. ÇAM (FISTIK ÇAMI) UÇUCU YAĞI

Author

SEVGİ, ECE, BÜYÜKKILIÇ ALTINBAŞAK, BETÜL, ZORLU, NİHAL, SALİHLER, KEVSER, KIZILARSLAN HANÇER, ÇAĞLA, KARTAL, MURAT, TOPÇU, GÜLAÇTI, and TOPÇU, GÜLAÇTI

Subjects
SEVGİ E., BÜYÜKKILIÇ ALTINBAŞAK B., ZORLU N., SALİHLER K., KIZILARSLAN HANÇER Ç., KARTAL M., TOPÇU G., -ÇAM (FISTIK ÇAMI) UÇUCU YAĞI-, Türk Farmakope Dergisi, cilt.5, ss.10-13, 2020
Published
2020

9. Çam (Anadolu Karaçamı) Uçucu YağıPine Nigra (Anatolian Black Pine) Essential Oil

Author

ZORLU, NİHAL, KIZILARSLAN HANÇER, ÇAĞLA, SALİHLER, KEVSER, SEVGİ, ECE, BÜYÜKKILIÇ ALTINBAŞAK, BETÜL, TOPÇU, GÜLAÇTI, KARTAL, MURAT, and TOPÇU, GÜLAÇTI

Subjects
BÜYÜKKILIÇ ALTINBAŞAK B., ZORLU N., SEVGİ E., SALİHLER K., KIZILARSLAN HANÇER Ç., KARTAL M., TOPÇU G., -Çam (Anadolu Karaçamı) Uçucu YağıPine Nigra (Anatolian Black Pine) Essential Oil-, TÜRK FARMAKOPE DERGİSİ, cilt.3, ss.13-17, 2020
Published
2020

10. Kapariden (Capparis ovata) izole edilen olean-12en-28ol, 3β pentakozanoat’xxın Multipl sklerozun tedavisi için etkinliğinin değerlendirilmesi: Sentezi ve DAE modelinde ilk veriler

Author

ŞEN, ALAATTİN, ÖZGÜN ACAR, ÖZDEN, ŞENOL, HALİL, EKEN, AHMET, DAĞ, AYDAN, TOPÇU, GÜLAÇTI, and TOPÇU, GÜLAÇTI

Subjects
Sentezi ve DAE modelinde ilk veriler-, 2. Uluslararası Türk Dünyası Multiple Skleroz Kongresi, 13 - 16 Şubat 2020 [ŞEN A., ÖZGÜN ACAR Ö., ŞENOL H., EKEN A., DAĞ A., TOPÇU G., -Kapariden (Capparis ovata) izole edilen olean-12en-28ol, 3β pentakozanoat’xxın Multipl sklerozun tedavisi için etkinliğinin değerlendirilmesi]
Published
2020

11. Selective in-vitro Enzymes- Inhibitory Activities of Fingerprints Compounds of Salvia Species and Molecular Docking Simulations

Author

ÖZHAN KOCAKAYA, ŞAFAK, ERTAŞ, ABDULSELAM, Yener, Ismail, Ercan, Bahadir, VARHAN ORAL, ELİF, Akdeniz, Mehmet, Kaplaner, Erhan, TOPÇU, GÜLAÇTI, Kolak, Ufuk, and TOPÇU, GÜLAÇTI

Subjects
Enzyme inhibition, Salvia, Nutrition, Molecular Docking, ÖZHAN KOCAKAYA Ş., ERTAŞ A., Yener I., Ercan B., VARHAN ORAL E., Akdeniz M., Kaplaner E., TOPÇU G., Kolak U., -Selective in-vitro Enzymes- Inhibitory Activities of Fingerprints Compounds of Salvia Species and Molecular Docking Simulations-, IRANIAN JOURNAL OF PHARMACEUTICAL RESEARCH, cilt.19, ss.187-198, 2020
Abstract

Recently Nutrition and Food Chemistry researches have been focused on plants and their products or their secondary metabolites having anti-alzheimer, anti-cancer, anti-aging, and antioxidant properties. Among these plants Salvia L. (Lamiaceae) species come into prominence with their booster effects due to high antioxidant contents, which have over 900 species in the world and 98 in Turkey. Some Salvia species are already in use as herbal treatment of vessel stiffness, Dementia like problems and cancer. Recently some species of Salvia are of extensive research topic. In this study, inhibitory potentials of secondary metabolites, rosmarinic acid, salvigenin, salvianolic acid A and B, tanshinone I and IIA, cyrtotanshinone, dihydrotanshinone I, carnosic acid, carnosol, and danshensu sodium salt were investigated against acetylcholinesterase, butyrylcholinesterase, urease and tyrosinase enzymes both in-vitro and in slico in detail. Elevated inhibitory effects on acetyl-and butyryl-cholinesterase of dihydrotanshinone I (IC50: 1.50 +/- 0.02 and 0.50 +/- 0.01 mu g/mL, respectively), carnasol (IC50: 11.15 +/- 0.05 ve 3.92 +/- 0.03 mu g/mL) and carnosic acid (IC50: 31.83 +/- 0.65 ve 4.12 +/- 0.04 mu g/mL) were observed. Furthermore, all other secondary metabolites were active against butyrylcholinesterase. Anti-urease (42.41 +/- 0.85%) and anti-tyrosinase (39.82 +/- 1.16%) activities of tanshinone I were also observed. Potential inhibitory effects of these molecules on target proteins were investigated using DOCK and molecular dynamics calculations. Dock score analysis and Lipinski parameters were demonstrated that these ligands are potential inhibitors against relevant enzymes. Our findings suggest that Salvia species can be utilized as a ptential source of anti-alzheimer active compounds for designing novel products. Türkiye Bilimsel Ve Teknolojik Araştırma Kurumu ( Tübitak )

Published
2020

13. Anticarcinogenic effect of a novel alkaloid: 1H-indole-2-hydroxy, 3-carboxylic acid

Author

ÖZGÜN ACAR, ÖZDEN, KALE, ELİF, GAZİOĞLU, IŞIL, TOPÇU, GÜLAÇTI, ŞEN, ALAATTİN, and TOPÇU, GÜLAÇTI

Subjects
1H-indole-2-hydroxy, 3-carboxylic acid-, 7th International congress of the Moleculer Biology Association of Turkey, 27 Eylül 2019 [ÖZGÜN ACAR Ö., KALE E., GAZİOĞLU I., TOPÇU G., ŞEN A., -Anticarcinogenic effect of a novel alkaloid]
Published
2019

15. Boron-s neurophysiological effects and tumoricidal activity on glioblastoma cells with implications for clinical treatment

Author

Altınöz, Meriç A., Elmacı, İlhan, TOPÇU, GÜLAÇTI, and TOPÇU, GÜLAÇTI

Subjects
inorganic chemicals, Altınöz M. A. , TOPÇU G., Elmacı İ., -Boron-s neurophysiological effects and tumoricidal activity on glioblastoma cells with implications for clinical treatment-, INTERNATIONAL JOURNAL OF NEUROSCIENCE, cilt.18, ss.1-15, 2019
Abstract

Purpose: To define the actions of boron on normal neurophysiology and glioblastoma growth. Materials and Methods: PubMed and other relevant databases were searched. Results: Discovery of novel boron compounds in treatment of glioblastoma is being actively investigated, but the majority of such studies is focused on the synthesis of boron compounds as sensitizers to Boron Neutron Capture Therapy (BNCT). Nonetheless, the translational functionality of boron compounds is not limited to BNCT as many boron compounds possess direct tumoricidal activity and there is substantial evidence that certain boron compounds can cross the blood-brain barrier. Moreover, boron-containing compounds interfere with several tumorigenic pathways including intratumoral IGF-I levels, molybdenum Fe-S containing flavin hydroxylases, glycolysis, Transient Receptor Potential (TRP) and Store Operated Calcium Entry (SOCE) channels. Conclusions: Boron compounds deserve to be studied further in treatment of systemic cancers and glioblastoma due to their versatile antineoplastic functions.

Published
2019

18. Adaçayı Yaprağı, Çok Gövdeli

Author

TOPÇU, GÜLAÇTI, TAN, NUR, GÜRDAL, BAHAR, TUFAN, SELİN, ERUÇAR, FATMA MEMNUNE, ALAN, ZINAR, AKALIN, EMİNE, and TOPÇU, GÜLAÇTI

Subjects
TOPÇU G., TAN N., GÜRDAL B., TUFAN S., ERUÇAR F. M. , ALAN Z., AKALIN E., -Adaçayı Yaprağı, Çok Gövdeli-, Türk Farmakope Dergisi, cilt.3, ss.40-42, 2018
Published
2018

19. Salvia multicaulis, Çok Gövdeli Adaçayı

Author

TOPÇU, GÜLAÇTI, TAN, NUR, AKALIN, EMİNE, ALAN, ZİNAR, GÜRDAL, BAHAR, TUFAN, SELİN, ERUÇAR, FATMA MEMNUNE, and TOPÇU, GÜLAÇTI

Subjects
TOPÇU G., TAN N., GÜRDAL B., TUFAN S., ERUÇAR F. M. , ALAN Z., AKALIN E., -Salvia multicaulis, Çok Gövdeli Adaçayı-, Türk Farmakope Dergisi, cilt.3, ss.126-132, 2018
Published
2018

21. Salvia Biotechnology

Author

ŞENOL, HALİL, Yücer, Rümeysa, TOPÇU, GÜLAÇTI, and TOPÇU, GÜLAÇTI

Subjects
TOPÇU G., Yücer R., ŞENOL H., Bioactive Constituents of Anatolian Salvia Species, -Salvia Biotechnology-, Georgiev V., Pavlov A., Editör, Springer International Publishing Ag, Part Of Springer Nature 2017, Cham, ss.31-132, 2018
Published
2018

23. Anti-inflammatory Effects of UA and OPC Isolated from Capparis ovata

Author

KALE, ELİF, ÖZGÜN ACAR, ÖZDEN, Abilo Alfa, Hajarat, GAZİOĞLU, IŞIL, TOPÇU, GÜLAÇTI, ŞEN, ALAATTİN, and GAZİOĞLU, IŞIL

Subjects
KALE E., ÖZGÜN ACAR Ö., Abilo Alfa H., GAZİOĞLU I., TOPÇU G., ŞEN A., -Anti-inflammatory Effects of UA and OPC Isolated from Capparis ovata-, 7th INTERNATIONAL CONGRESS of THE MOLECULAR BIOLOGY ASSOCIATION of TURKEY, İstanbul, Türkiye, 27 - 29 Eylül 2019, cilt.44, ss.16
Published
2019

24. Synthesis And Initial Evaluation Of Efficacy Of Olean-12-En-28-Ol, 3 Beta-Pentacosanoate For The Symptomatic Treatment Of Multiple Sclerosis

Author

DAĞ, AYDAN, Sen, A., Acar, O. Ozgun, ŞENOL, HALİL, Kale, E., TOPÇU, GÜLAÇTI, AGÜ, Yaşam ve Doğa Bilimleri Fakültesi, Moleküler Biyoloji ve Genetik Bölümü, and DAĞ, AYDAN

Subjects
Induced pluripotent cells, Sen A., ŞENOL H., Acar O. O. , Kale E., DAĞ A., TOPÇU G., -Synthesis and initial evaluation of efficacy of olean-12-en-28-ol, 3 beta-pentacosanoate for the symptomatic treatment of multiple sclerosis-, FEBS OPEN BIO, cilt.9, ss.74, 2019
Abstract

This work was supported by the Scientific and Technological Research Council of Turkey [TUBITAK-117S293]. [Özet Yok] Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) TUBITAK-117S293

Published
2019

25. Analysis of 1H-indole-2-hydroxy, 3 carboxylic acid isolated from Capparis ovata for the treatment of MS: lack of evidence for the efficacy

Author

ÖZGÜN ACAR, ÖZDEN, GAZİOĞLU, IŞIL, TOPÇU, GÜLAÇTI, ŞEN, ALAATTİN, and TOPÇU, GÜLAÇTI

Subjects
lack of evidence for the efficacy-, 5th International Congress of the Molecular Biology Association of Turkey, 8 September - 10 December 2017, ss.163 [ÖZGÜN ACAR Ö., GAZİOĞLU I., TOPÇU G., ŞEN A., -Analysis of 1H-indole-2-hydroxy, 3 carboxylic acid isolated from Capparis ovata for the treatment of MS]
Published
2017

26. A promising Neuroprotective Agent for the Treatment of Multiple Sclerosis: 3-beta-Hydroxyolean-12-en-28-oate İsolated from Capparis ovata

Author

ŞEN, ALAATTİN, ÖZGÜN ACAR, Özden, GAZİOĞLU, IŞIL, TOPÇU, GÜLAÇTI, and TOPÇU, GÜLAÇTI

Subjects
3-beta-Hydroxyolean-12-en-28-oate İsolated from Capparis ovata-, The 3 rd International Symposium on EuroAsian Biodiversity, 5 - 08 July 2017, ss.85 [ŞEN A., ÖZGÜN ACAR Ö., GAZİOĞLU I., TOPÇU G., -A promising Neuroprotective Agent for the Treatment of Multiple Sclerosis]
Published
2017

27. Treatment of Ulcerative Colitis Disease with Rosmarinus officinalis

Author

YILMAZ, ANIL, UÇKAYA, FATİH, Bayındır, Nihan, TOPRAK, ALİ, GÜLER, ERAY METİN, EŞREFOĞLU, MUKADDES, TOPÇU, GÜLAÇTI, UÇKAYA, FATİH, and TOPÇU, GÜLAÇTI

Subjects
YILMAZ A., UÇKAYA F., Bayındır N., TOPRAK A., GÜLER E. M. , EŞREFOĞLU M., TOPÇU G., -Treatment of Ulcerative Colitis Disease with Rosmarinus officinalis-, International Symposium on Advances in Lamiaceae Science, 26 - 29 Nisan 2017, YILMAZ A., UÇKAYA F., Bayındır N., TOPRAK A., GÜLER E. M. , EŞREFOĞLU M., TOPÇU G., -Treatment of Ulcerative Colitis Disease with Rosmarinus officinalis-, Natural Volatiles Essential Oils, cilt.4, ss.33, 2017
Published
2017

28. Ursolik Asit ve Oleanolik Asitten Hareketle alfa-Amirin ve beta-Amirin Sentezi için Yeni ve Etkin Bir Yöntem

Author

SEÇEN, HASAN, ŞENOL, HALİL, TOPÇU, GÜLAÇTI, TUNCAY, SALİH, ÖCAL, NÜKET, and TOPÇU, GÜLAÇTI

Subjects
ŞENOL H., TUNCAY S., SEÇEN H., ÖCAL N., TOPÇU G., -Ursolik Asit ve Oleanolik Asitten Hareketle alfa-Amirin ve beta-Amirin Sentezi için Yeni ve Etkin Bir Yöntem-, 3rd International Convention of Pharmaceuticals and Pharmacies, İstanbul, Türkiye, 26 April 2017, ss.608-609
Published
2017

30. Scavenging Effects of 3,4-dihydroxybenzaldehyde on DPPH Free Radical

Author

ERENLER, R, ELMASTAS, M, Adak, Tuğba, TOPÇU, GÜLAÇTI, and TOPÇU, GÜLAÇTI

Subjects
İlaç Etkin Maddesi Tasarımı, Sentezi, Üretimi ve Standardizasyonu Kongresi, Antalya, Türkiye, 30 March 2017, ss.1 [ERENLER R., ELMASTAS M., Adak T., TOPÇU G., -Scavenging Effects of 3,4-dihydroxybenzaldehyde on DPPH Free Radical-, Uluslararası Katılımlı 5. İlaç Kimyası]
Published
2017

31. Oleanolik Asit Türevlerinin Sentezi ve Sitotoksik Aktivitelerinin Araştırılması

Author

TUNCAY, SALİH, ŞENOL, HALİL, GÜLER, ERAY METİN, ÖCAL, NÜKET, SEÇEN, HASAN, KOÇYİĞİT, ABDÜRRAHİM, TOPÇU, GÜLAÇTI, and TOPÇU, GÜLAÇTI

Subjects
İlaç Etkin Maddesi Tasarımı, Sentezi, Üretimi ve Standardizasyonu Kongresi, Antalya, Türkiye, 30 March 2017, ss.166 [TUNCAY S., ŞENOL H., GÜLER E. M. , ÖCAL N., SEÇEN H., KOÇYİĞİT A., TOPÇU G., -Oleanolik Asit Türevlerinin Sentezi ve Sitotoksik Aktivitelerinin Araştırılması-, Uluslararası Katılımlı 5. İlaç Kimyası]
Published
2017

32. Comparative Study of the Anti-inflammatory Effects of Sub-extracts of the Capparis ovata Water Extract (COWE) Used as an Alternative and Complementary Treatment for Multiple Sclerosis

Author

ÖZGÜN ACAR, ÖZDEN, GAZİOĞLU, IŞIL, TOPÇU, GÜLAÇTI, ŞEN, ALAATTİN, and TOPÇU, GÜLAÇTI

Subjects
ЕСТЕСТВЕННЫЕ И ТОЧНЫЕ НАУКИ::Биология [ЭБ БГУ], ÖZGÜN ACAR Ö., GAZİOĞLU I., TOPÇU G., ŞEN A., -Comparative Study of the Anti-inflammatory Effects of Sub-extracts of the Capparis ovata Water Extract (COWE) Used as an Alternative and Complementary Treatment for Multiple Sclerosis-, The 3 rd International Symposium on EuroAsian Biodiversity, 5 - 08 July 2017, ss.163
Published
2017

33. Salvia absconditilifolia, (Sin.: S. crypthantha), Kara Şalba

Author

TAN, Nur, AKALIN, EMİNE, EKİNCİ, MİRAÇ, YEŞİL, YETER, YAZICI TÜTÜNİŞ, SEÇİL, TOPÇU, GÜLAÇTI, ALİM, GÜLBAHAR ÖZGE, and ALİM TORAMAN, Gülbahar Özge

Subjects
S. crypthantha), Kara Şalba-, Türk Farmakope Dergisi, cilt.3, ss.133-139, 2018 [TAN N., YAZICI TÜTÜNİŞ S., YEŞİL Y., ALİM G. Ö. , EKİNCİ M., AKALIN E., TOPÇU G., -Salvia absconditilifolia, (Sin.]
Published
2018

35. Ursolik Asit ve Türevinin Meme Kanseri Hücre Hattı Üzerinde Sitotoksik Etkilerinin İncelenmesi

Author

BÜTÜN, BURCU, Türker Şener , Leyla, Birman, Hüsniye, Albeniz, Işıl, TOPÇU, GÜLAÇTI, and TOPÇU, GÜLAÇTI

Subjects
BÜTÜN B., Türker Şener L., Birman H., Albeniz I., TOPÇU G., -Ursolik Asit ve Türevinin Meme Kanseri Hücre Hattı Üzerinde Sitotoksik Etkilerinin İncelenmesi-, 42. Ulusal Fizyoloji Kongresi, Düzce, Türkiye, 11 September 2016, cilt.218, ss.37
Published
2016

36. Effect of a combination in situ gel-forming nasal delivery system on nasal mucosa damage repair in rabbits

Author

AKSOY, FADLULLAH, DOĞAN, REMZİ, OZTURAN, ORHAN, ALTUNTAŞ, EBRU, YENER, FATMA GÜLGÜN, TOPÇU, GÜLAÇTI, GÜLER, BERİL, and ÖZTURAN, ORHAN

Subjects
AKSOY F., DOĞAN R., OZTURAN O., ALTUNTAŞ E., YENER F. G. , TOPÇU G., GÜLER B., -Effect of a combination in situ gel-forming nasal delivery system on nasal mucosa damage repair in rabbits-, 4th Congress of European ORL-HNS, 7 - 11 October 2017
Published
2017

37. The Insulinoma Cells are Death as Destination with Nanoparticulars Loaded Esculetin

Author

BAHADORİ, FATEMEH, Karatuğ, A., TEKKELİ, ŞERİFE EVRİM, TOPÇU, GÜLAÇTI, Bolkent, Ş., and BAHADORİ, FATEMEH

Subjects
BAHADORİ F., Karatuğ A., TOPÇU G., TEKKELİ Ş. E. , Bolkent Ş., -The Insulinoma Cells are Death as Destination with Nanoparticulars Loaded Esculetin-, 4th Internatıonal conference on materials science and nanotechnology for next generation (MSNG2017), Sarajevo, Bosna-Hersek, 28 June 2017, ss.1
Published
2017

38. Yeni Bromo İndenokinolinamin Türevlerinin Anti Alzhemier Ajanlar olarak Biyolojik Aktivitelerinin Değerlendirilmesi

Author

Ökten, Salih, Ekiz, Makbule, BÜTÜN, BURCU, Tutar, ahmet, TOPÇU, GÜLAÇTI, and BÜTÜN, Burcu

Subjects
Ekiz M., Tutar a., Ökten S., BÜTÜN B., TOPÇU G., -Yeni Bromo İndenokinolinamin Türevlerinin Anti Alzhemier Ajanlar olarak Biyolojik Aktivitelerinin Değerlendirilmesi-, 3. Uluslararası İlaç ve Eczacılık Kongresi, İstanbul, Türkiye, 26 April 2017, ss.125
Published
2017

40. Oleanolik Asitten Hareketle alfa-Amirin ve beta- Amirin Sentezi için Yeni ve Etkin Bir Yöntem

Author

ŞENOL, HALİL, TUNCAY, SALİH, SEÇEN, HASAN, ÖCAL, NÜKET, TOPÇU, GÜLAÇTI, and ŞENOL, Halil

Subjects
ŞENOL H., TUNCAY S., SEÇEN H., ÖCAL N., TOPÇU G., -Oleanolik Asitten Hareketle alfa-Amirin ve beta- Amirin Sentezi için Yeni ve Etkin Bir Yöntem-, 3rd International Convention of Pharmaceuticals and Pharmacies, İstanbul, Türkiye, 6 - 29 Nisan 2017
Published
2017

41. Preparation and Cytotoxic Activities of Silver-Graphene Nanocomposites Loaded with Curcumin for Drug Delivery Systems

Author

ŞENOL, HALİL, TOPÇU, GÜLAÇTI, ŞENOL, AYŞE MERVE, ONGANER, YAVUZ, BAHADORİ, FATEMEH, and ŞENOL, Halil

Subjects
ŞENOL A. M. , BAHADORİ F., ŞENOL H., TOPÇU G., ONGANER Y., -Preparation and Cytotoxic Activities of Silver-Graphene Nanocomposites Loaded with Curcumin for Drug Delivery Systems-, 3rd International Convention of Pharmaceuticals and Pharmacies, İstanbul, Türkiye, 26 April 2017, ss.996-997
Published
2017

42. Bazı Uvaol Türevlerinin Sentezi ve in vitro Biyokaitivitelerininİncelenmesi

Author

ŞENOL, HALİL, TUNCAY, SALİH, GÜLER, ERAY METİN, SEÇEN, HASAN, KOÇYİĞİT, ABDURRAHİM, ÖCAL SUNGUROĞLU, ZEHRA NÜKET, AKDEMİR, ATİLLA, TOPÇU, GÜLAÇTI, and AKDEMİR, ATİLLA

Subjects
ŞENOL H., TUNCAY S., GÜLER E. M. , SEÇEN H., ÖCAL SUNGUROĞLU Z. N. , AKDEMİR A., KOÇYİĞİT A., TOPÇU G., -Bazı Uvaol Türevlerinin Sentezi ve in vitro Biyokaitivitelerininİncelenmesi-, IVEK 3rd International Convention of Pharmaceuticals and Pharmacies3. Uluslararası İlaç ve Eczacılık Kongresi, İstanbul., 26 Nisan - 29 Ocak 2017
Published
2017

44. Nükleer Faktör Kappa-B İnhibisyon Etkili Ursan Türevi Triterpenlerin Sentezi

Author

TUNCAY, SALİH, SEÇEN, HASAN, ÖCAL, NÜKET, TOPÇU, GÜLAÇTI, AKDEMİR, ATİLLA, ŞENOL, HALİL, and ŞENOL, Halil

Subjects
İlaç Etkin Maddesi Tasarımı, Sentezi, Üretimi ve Standardizasyonu Kongresi, Antalya, Türkiye, 30 March 2017, ss.131 [ŞENOL H., TUNCAY S., SEÇEN H., ÖCAL N., AKDEMİR A., TOPÇU G., -Nükleer Faktör Kappa-B İnhibisyon Etkili Ursan Türevi Triterpenlerin Sentezi-, Uluslararası Katılımlı 5. İlaç Kimyası]
Published
2017

45. Investigation of the Anti-inflammatory Potential of Glucocapparin Isolated from Capparis ovata

Author

ÖZGÜN ACAR, ÖZDEN, GAZİOĞLU, IŞIL, TOPÇU, GÜLAÇTI, ŞEN, ALAATTİN, and GAZİOĞLU, IŞIL

Subjects
ЕСТЕСТВЕННЫЕ И ТОЧНЫЕ НАУКИ::Биология [ЭБ БГУ], ÖZGÜN ACAR Ö., GAZİOĞLU I., TOPÇU G., ŞEN A., -Investigation of the Anti-inflammatory Potential of Glucocapparin Isolated from Capparis ovata-, The 3 rd International Symposium on EuroAsian Biodiversity, 5 - 08 July 2017, ss.483
Published
2017

46. Antiprotease and Antioxidant Activities of Salvia montbretii

Author

Uçakaya, Meryem, UÇKAYA, FATİH, BEKTAY, MUHAMMED YUNUS, TOPÇU, GÜLAÇTI, and TOPÇU, GÜLAÇTI

Subjects
Uçakaya M., UÇKAYA F., BEKTAY M. Y. , TOPÇU G., -Antiprotease and Antioxidant Activities of Salvia montbretii.-, International Multidisciplinary Symposium on Drug Research & Development, Eskişehir, Türkiye, 15 October 2015, ss.76
Published
2015

47. Investigation of Anti-Oxidant and Toxicological Effects Of Methanolic Extract of Rosmarinus officinalis

Author

BEKTAY, MUHAMMED YUNUS, UÇKAYA, FATİH, BAYINDIR, NİHAN, TOPÇU, GÜLAÇTI, EŞREFOĞLU, MUKADDES, and TOPÇU, GÜLAÇTI

Subjects
BEKTAY M. Y. , UÇKAYA F., BAYINDIR N., TOPÇU G., EŞREFOĞLU M., -Investigation of Anti-Oxidant and Toxicological Effects Of Methanolic Extract of Rosmarinus officinalis-, International Multidisciplinary Symposium on Drug Research & Development, Eskişehir, Türkiye, 15 October 2015, ss.65
Published
2015

49. Biological Activities and Chemical Composition of Ferulago idaea

Author

Aslan, Esin, DİNCEL, DEMET, Çakar, Begüm, TOPÇU, GÜLAÇTI, and TOPÇU, GÜLAÇTI

Subjects
Aslan E., DİNCEL D., Çakar B., TOPÇU G., -Biological Activities and Chemical Composition of Ferulago idaea-, 11th International Symposium on Pharmaceutical Sciences, Ankara, Türkiye, 09 June 2015, ss.348
Published
2015

50. Three phase partitioning of peroxidase from opuntia-ficus indica and its utility for decolorizatıon of synthetic dyes

Author

UÇKAYA, FATİH, UÇKAYA, MERYEM, GÜLER, ERAY METİN, TOPÇU, GÜLAÇTI, and TOPÇU, GÜLAÇTI

Subjects
UÇKAYA F., UÇKAYA M., GÜLER E. M. , TOPÇU G., -Three phase partitioning of peroxidase from opuntia-ficus indica and its utility for decolorizatıon of synthetic dyes-, International Multidisciplinary Symposium on Drug Research and Development 2015, Eskişehir, Türkiye, 15 - 17 Mayıs 2015, UÇKAYA F., UÇKAYA M., GÜLER E. M. , TOPÇU G., -Three Phase Partitioning of Peroxidase from Opuntia-ficus indica and Its Utility for Decolorization of Synthetic Dyes-, International Multidisciplinary Symposium on Drug Research & Development, Eskişehir, Türkiye, 15 - 17 Eylül 2015
Published
2015

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