Search

BackgroundThere is growing recognition that reproductive factors are associated with increased risk of future cardiovascular disease. Infertility has been less well studied, although emerging data support its association with increased risk of cardiovascular disease. Whether infertility is associated with future risk of heart failure (HF) is not known.ObjectivesThis study sought to examine the development of HF and HF subtypes in women with and without history of infertility.MethodsWe followed postmenopausal women from the Women's Health Initiative prospectively for the development of HF. Infertility was self-reported at study baseline. Multivariable cause-specific Cox models were used to evaluate the association of infertility with incident overall HF and HF subtypes (heart failure with preserved ejection fraction [HFpEF]: left ventricular ejection fraction of ≥50% vs heart failure with reduced ejection fraction [HFrEF]: left ventricular ejection fraction of

Online education materials are widely used by patients and caregivers to understand the management of complex chronic diseases such as heart failure (HF). Organizations such as the American Medical Association and National Institutes of Health recommend that materials be written at a 6th-grade reading level. The current study examined the readability and accessibility of online education materials for patients with HF. Whole page texts from each included website were entered into an online readability calculator. Five validated readability indices (Flesch-Kincaid Grade Level, Flesch Reading Ease Scale, Gunning Fog Index, Coleman-Liau Index, and Simple Measure of Gobbledygook (SMOG Index)) were used to evaluate each source. Websites were categorized by source (government, public and private). The availability of audiovisual accessibility features and content in non-English languages were assessed for each website. Of the 36 online resources analyzed, the median readability level was 9th–10th grade according to the Flesch-Kincaid Grade Level and college level, according to the Flesch Reading Ease Scale. The Gunning Fog Index and Coleman-Liau Index both showed median readability scores corresponding to a 12th grade reading level, whereas the SMOG Index showed a median score corresponding to that of the 9th grade. Only 10 websites (28%) offered information in languages other than English, and none provided comprehensive accessibility features for users with disabilities. Common online educational materials for patients with HF are characterized by higher readability levels than those recommended by the National Institutes of Health and the American Medical Association, and there were limited multilingual and accessibility options, potentially limiting the accessibility of resources to patients and caregivers. [ABSTRACT FROM AUTHOR]

Financial considerations continue to impact access to heart transplantation. Transplant recipients face various costs, including, but not limited to, the index hospitalization, immunosuppressive medications, and lodging and travel to appointments. In this study, we sought to describe the state of crowdfunding for individuals being evaluated for heart transplantation. Using the search term heart transplant , 1000 GoFundMe campaigns were reviewed. After exclusions, 634 (63.4%) campaigns were included. Most campaigns were in support of white individuals (57.8%), males (63.1%) and adults (76.7%). Approximately 15% of campaigns had not raised any funds. The remaining campaigns fundraised a median of $53.24 dollars per day. Of the patients, 44% were admitted at the time of the fundraising. Within the campaigns in the United States, the greatest proportions were in the Southeast United States in non-Medicaid expansion states. These findings highlight the significant financial toxicities associated with heart transplantation and the need for advocacy at the governmental and payer levels to improve equitable access and coverage for all. [ABSTRACT FROM AUTHOR]

Introduction: Effective communication and understanding are imperative for heart transplant (HT) recipients who require lifelong adherence to treatment plans and medications. Whether non-native English speaking (NNES) recipients have inferior outcomes compared to native English-speaking recipients (NES) has not been studied post-HT., Methods: We reviewed adult HT recipients at Columbia University Irving Medical Center from January 2005 through December 2022 with primary language determined by chart review. Baseline characteristics and patient level zip codes which were used to derive socioeconomic status (SES) index using data from the Agency for Healthcare Research and Quality (AHRQ) were included. Mortality at 1-year and 5-year was compared between NNES and NES. Survival curves were estimated by the Kaplan-Meir method and log-rank testing was used to compare survival between groups. Secondary outcomes including hospitalization, hospitalization for infection, and rejection at 1-year, as well as rejection and CAV at 5-years were analyzed using cumulative incidence functions with Gray's testing to detect outcome differences between groups. Multivariable Cox proportional hazard models were constructed to determine if there was an association between NNES and primary and secondary outcomes., Results: Of 1,066 HT recipients, 103 (10%) were NNES. NNES recipients were more likely to identify as non-White, have Medicaid as the primary payer, and have lower educational attainment. On average, NNES recipients resided in zip codes with higher levels of unemployment, lower educational attainment, and lower household incomes. Overall, NNES had lower median AHRQ SES indices (51 vs 55, p<0.001). After adjustment for clinical factors including socioeconomic status, race/ethnicity, and education level, mortality at 1- and 5-years for NNES and NES recipients were not significantly different although there was a trend towards improved survival in the NNES group (1-year adjusted hazard ratio (HR) 0.24, 95% CI 0.06-1.01, p=0.05; 5-year adjusted HR 0.48, 95% CI 0.22-1.03, p=0.06). Similarly, there were no differences in need for re-hospitalization, infection requiring hospitalization, and rejection at 1 year., Conclusions: There were no significant differences in outcomes at 1 year and 5 years post-HT among NNES and NES. Availability of interpreter services and educational resources in multiple languages are paramount to maintaining effective communication and equitable outcomes., Lay Summary: Although the population of individuals living with heart failure in the United States is incredibly diverse, little is known about whether non-Native English speakers (NNES) fare differently after heart transplantation. In this study of over 1000 heart transplant recipients, we found that although NNES patients were more likely to be non-White, had lower education status and had public insurance, outcomes were similar at 1- and 5-years after transplant., (Copyright © 2025. Published by Elsevier Inc.)