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2 results on '"T2*gradient echo MRI"'

1. Role of T2* GRE MRI Sequence in Detecting Cerebral Microbleeds in Hypertensive Patients Presenting with Intra Cerebral Hemorrhage

Author

Muhammad Imran Khan, Neelum Aizaz, Fariha Afzal, and Nosheen

Subjects
Intracerebral hemorrhage (ICH), Cerebral microbleeds (CMBs), Hypertension, T2*gradient echo MRI, Susceptibility weighted images (SWI), Dentistry, RK1-715, Medicine (General), R5-920
Abstract

OBJECTIVES Examine the efficacy of T2* gradient echo in detecting Cerebral microbleeds (CMBs) among hypertensive patients, emphasizing its efficiency in acquisition time. Evaluate its potential as an alternative to susceptibility-weighted imaging (SWI) in routine assessments for hypertensive individuals. METHODOLOGY A cross-sectional study from Sep 2021 to January 2023 was conducted at the Radiology Unit of Lady Reading Hospital Peshawar. Patients suspected of having a cerebrovascular accident (CVA) were referred from different units who had proven Intracerebral hemorrhage (ICH) on initial CT brain. The exclusion criteria were a history of recent trauma aneurysms/tumors on the present scan. The MRI examination included sequences like T1, T2, FLAIR, DWI/ADC, and T2*. The CMB was defined as a hypointense focus of signal drops out, measuring 5-10mm, with blooming artefact on T2* images and no surrounding edema. RESULTS 62 patients were included in the study, with an equal proportion of males and females and age ranges between 46 to 78 years (62 ± 4.7). Forty-one cases had CMBs on T2* sequence in these 62 cases (66%), and 18 (44%) cases out of 41 were visible on T2WI. No significant correlation was seen between grades of CMBs and the location or size of the microbleed on Spearman’s test. CONCLUSION T2*GRE weighting can effectively detect CMBs compared to SWI. Therefore, this sequence could be employed in hospitals with increased workloads due to short acquisition time instead of the longer time for SWI.

Published
2024

2. Microbleeding in the Head of Caudate Nuclei of a Patient with Hypertension

Author

Keiji Shimizu, Yoriko Murata, Hikaru Mizobuchi, Shoji Yoshida, Seisho Takeuchi, and Hironobu Ue

Subjects
hypertension, head of caudate nuclei, cerebral bleeding, Internal Medicine, medicine, Humans, In patient, Cerebral Hemorrhage, medicine.diagnostic_test, business.industry, Nodule (medicine), General Medicine, Middle Aged, Magnetic Resonance Imaging, Radiography, Treatment Outcome, T2*-weighted gradient echo MRI, Hemosiderin, Angiography, Female, Caudate Nucleus, medicine.symptom, Abnormality, Nuclear medicine, business, Cerebral Bleeding, Gradient echo
Abstract

headache for one month. MRI revealed a small expanded nodule in the head of the right caudate nuclei (Fig. 1). It was hyper intense on both T1(left) and T2-weighted (right) images. Bleeding was suspected, however, other causes including tumor could not be excluded at this time. Subsequent angiography showed no abnormality. Her symptom disappeared gradually without any treatment. Four weeks later, T2*-weighted gradient echo (GRE) MRI was performed (Fig. 2). Many small round lesions with signal loss were found in the head of the caudate nuclei (left), and in other deep structures (right). Such multifocal small hypointense lesions on T2*-weighted GRE MRI are made from hemosiderin after microbleeding. These microbleedings sometimes occur in patients with hypertension. She was diagnosed as having microbleeding due to hypertension. Although microbleeding in the head of the caudate nuclei is uncommon, it should be always considered in patients with hypertension. T2*-weighted GRE MRI was very useful in confirming the diagnosis.

Published
2004
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