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Introduction. As household insecticidal agents for mosquito control, electric fumigators are used complete with plates and/or liquid, which can pose an inhalation hazard during work. Material and methods. The toxicity and danger of five samples of electrofumigators on the basis of transfluthrin and prallethrin in the form of liquid and plates were studied. Two modes of application of electric fumigators have been tested: with 30-minutes airing after an hour-long treatment and further stay in the room of people and with the continuous operation of the electric fumigator in a ventilated room in the presence of people. High-performance liquid chromatography was used to determine the active substances in the air; the sensitivity of the method was 0.001 mg / m3. The assessment of the acute inhalation hazard of volatile components released during the operation of the electric fumigator was carried out on white outbred rats. Results. The obtained data showed that when using electric fumigators on transfluthrin and prallethrin, they are observed to increase in the air as compared with the hygienic standards established for them for the atmospheric air of populated areas. The research results depended on the form of the product and the chosen mode of application. Thus, assessing the first mode of application of the plates on transfluthrin, it was revealed that 30 minutes of airing the room is not enough, the excess of environmental tentative safe exposure levels was recorded. The study of the second mode of application of fluid and plates on transfluthrin revealed a tendency to increase its content in the air of the treated room when using both forms. When using the second mode of application of the liquid and the plates on prallethrin, it that after 1 h of operation of the electrofumigator with liquid, the concentration of prallethrin significantly was revealed to exceed the hygienic standard. Conclusion. The use of electrofumigators working for 8 hours in the presence of people is not recommended for use, it is necessary to ventilate the room when the fumigator is in operation for more than 1 hour.

The authors made an attempt to show the differentiation and integration of preventive medical Sciences and ecological disciplines as a complex dialectical process characteristic for the development of the science of the late 20th - early 21st centuries, and to analyze the methodological links of preventive medical Sciences with numerous ecological disciplines developed in recent decades. The article deals with the processes of formation of new ecological disciplines studying the system “environment - human”, a comparative analysis of preventive medical and environmental Sciences on their goals, subjects and objects of study. The study of the environmental impact on human health was shown to be carried out by already formed medical Sciences, and primarily preventive orientation (General hygiene, Social hygiene, Communal hygiene, Food hygiene, Occupational health, Military hygiene, Radiation hygiene, etc.), having accumulated considerable experience in the areas of knowledge studied by them. Disciplines arising from the differentiation of the environment and studying the preservation of life and health, in essence, duplicate preventive medical Sciences, which inevitably leads to the repetition of the path and does not give the desired results in the increment and development of new scientific knowledge. At the same time, the process of interaction and unification of efforts of preventive medical Sciences and environmental disciplines can make a significant contribution to the successful solution of such important state tasks as the preservation of public health and environmental protection from the negative impact of anthropogenic factors. The application of a systematic interdisciplinary approach in the interaction of preventive medical Sciences and environmental disciplines involves the presence of scientific facts, a complex of deep knowledge in the areas under study, the development of a number of theories, as well as the analysis of environmental and medical problems.

The widespread formation of unfavorable environmental, the swiftness of modern life with large information and psycho-emotional loads and extremely natural and climatic cataclysms, as well as harmful addictions and wrong way of life of modern human, lead to the development of stress and disruption of the mechanisms of adaptation of the human body and its accelerated wear. This stimulates the development of research on the creation of new methods of integrated assessment of health and quantitative assessment of the aging processes of the body systems and the whole body, as well as the possibilities of new methods of risk assessment of climatic and environmentally related pathological and age-related diseases. The aim of the work was to consider the methodology of quantitative assessment of individual health and the rate of aging of the human body on the basis of the system index of Biological age (BA); description of its essence and structure, requirements for tests - biomarkers of aging used as the index of BA, definition of possibilities and scope of application of the BA method in modern practice of Biomedicine. The use of modern methods of scientific analysis - a systematic approach to the analysis of the processes of human aging and determine its quantitative side - the value of BA, allows a reasonable approach to the choice of the number of BM, to take into account their information content and precision, and the cost of diagnostics and availability for different users, to take into account the specific objectives of the researcher. The use of the index-partial BA allows individual approaching the choice of biomarkers and create personalized panels for the definition of BA programs for the prevention of aging in personalized preventive medicine. The complexity of the content and calculation of indices of BA requires automation and the use of methods of modern computer science and computer calculations and programs. For this purpose, we have created special computer software for diagnosing aging by calculating the BA indices with the possibility of choosing BM and automatic calculation of indicators and conclusions.

Introduction. The article discusses the results of a general analysis of information on the radiation-hygienic passports of Moscow in the period from 2013 to 2016, providing objective and accessible information about the characteristics of all sources of ionizing radiation (man-made, medical, natural) and the resulting radiation doses for the population Moscow. Material and methods. A qualitative and quantitative assessment of doses for the population from natural sources, medical exposure of patients during X-ray examinations was carried out, the objects of Moscow using sources were studied. Results. The number of sources in Moscow has been established to be indicated inaccurately, as a result of which unaccounted sources are identified during control and supervisory measures. The leading role in the structure of collective doses of radiation to the population of Moscow according to the data of 2016 was shown to come from natural sources and medical research as much as 81.5 and 18.3%, respectively. A continuous increase in the dose from computed tomography and its significant contribution to the collective dose from medical exposure of Moscow residents was noted. In 2016, its contribution amounted to 59.9%. Discussion. To determine the qualitative and quantitative assessment of the doses to the population of Moscow from all sources, the radiation hygienic passports of the city of Moscow were studied from 2013 to 2016. Conclusions. On the basis of the study conducted to assess the doses of radiation to the population of Moscow, an underestimation of the effective doses of patients during medical research was established. There is a continuous increase in the dose from computed tomography, its significant contribution to the collective dose from medical exposure of the population of Moscow. In order to update the radiation hygienic passport of Moscow, it is necessary to achieve the presentation of complete information by objects using sources, as well as the relevance of legal acts, taking measures to prevent an unreasonable increase in doses of medical exposure to residents of Moscow while actively introducing highly informative diagnostic methods in medicine.

In this work, the wavelet spectra were calculated and studied for time series representing the dynamics of the new cases of coronavirus infection in France, Sweden and China. It was found that the Wavelet spectra for these countries have characteristic different-scale internal cycles, the number of which depends on the nature of the quarantine activities. It was detected that structure of the Wavelet spectra, their duration is practically independent of the geographic location, density and population size.

The acute toxicity of phosphogypsum and its derivatives was studied. The agents were found to be low and moderate toxic.

The process of phosphor-gyps is associated with the pollution of the working environment by aerosols containing Ca, Fe, Si, P, fluorides, and other substances. Sanitary measures for the working environment and studies of the aerosol effects on human health are proposed.

Phosphogypsum is waste of phosphoric acid production. It is used in the manufacture of various building materials. Industrial conditions in this production were studied. The study showed the presence of various dusts in air. Recommendations for improvement of working zone air were given.

Study of labour conditions in mining and processing of polymineral potassium ore was conducted. It was shown, that air and lighting conditions and vibrations are more severe under mining, than under processing of potassium ore.

In the processing of the waste products of phosphorus containing fertilizer production, several major health-related factors were identified depending on the industrial site's peculiarities: unfavourable microclimate conditions (both cold and heat), relative temperature differences, noise and vibration caused by the equipment, semi-product's, additives' and finished product's dusts, fluorine- and phosphorus-containing substances' affects and poor illumination. The proposed data were used for health-related improvements in the occupational conditions.