1. Are plasma endotoxin levels related to burn size and prognosis?
- Author
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M. Kondo, T. Kasoi, Shuitsu Hoshi, Shigeatsu Endo, M. Suzuki, Y Yamada, Katsuya Inada, H. Yamashita, Masao Yoshida, and M. Kikuchi
- Subjects
Adult ,Aged, 80 and over ,Male ,Body surface area ,medicine.medical_specialty ,Adolescent ,business.industry ,Clinical course ,General Medicine ,Middle Aged ,Prognosis ,Critical Care and Intensive Care Medicine ,Surgery ,Endotoxins ,Anesthesia ,Emergency Medicine ,medicine ,Humans ,Female ,Burns ,Child ,business ,Limulus Test ,Aged - Abstract
Plasma endotoxin concentrations were determined in 42 patients with burns covering more than 20 per cent of the body surface area, using the endotoxin-specific Endospecy assay and treatment of plasma by a new method developed by ourselves. The normal endotoxin level was 9.8 pg/ml or less. In the early period after injury when no infection was present, very few patients had an endotoxin level above 9.8 pg/ml and endotoxin levels did not correlate with the area of the burns or with prognosis. However, later in the clinical course, endotoxin levels were correlated significantly with the burned area and with the prognosis.
- Published
- 1992