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1. Microbial mimics supersize the pathogenic self-response

2. HLA A*24:02-restricted T cell receptors cross-recognize bacterial and preproinsulin peptides in type 1 diabetes

3. Reports from Technical University Munich (TU Munich) Add New Data to Research in Hepatitis B Virus (CARs derived from broadly neutralizing, human monoclonal antibodies identified by single B cell sorting target hepatitis B virus-positive cells)

4. University Medical Center Utrecht Researchers Update Current Study Findings on Engineered T-Cells (Combining CRISPR-Cas9 and TCR exchange to generate a safe and efficient cord blood-derived T cell product for pediatric relapsed AML)

5. Neurocognitive and hypokinetic movement disorder with features of parkinsonism after BCMA-targeting CAR-T cell therapy

6. The role of chromatin organizer Satb1 in shaping TCR repertoire in adult thymus

7. Locoregional infusion of HER2-specific CAR T cells in children and young adults with recurrent or refractory CNS tumors: an interim analysis

8. A Primer on Chimeric Antigen Receptor T-cell Therapy: What Does It Mean for Pathologists?

9. Data on Personalized Medicine Described by Researchers at University of Colorado (Dysregulated Lymphocyte Antigen Receptor Signaling In Common Variable Immunodeficiency With Granulomatous Lymphocytic Interstitial Lung Disease)

10. Characteristics of anti-CD19 CAR T cell infusion products associated with efficacy and toxicity in patients with large B cell lymphomas

11. University of Massachusetts Chan Medical School Researcher Discusses Findings in Influenza A Virus (CD4 Effector TCR Avidity for Peptide on APC Determines the Level of Memory Generated)

12. Researcher at University of Toronto Publishes New Study Findings on Cancer (Abstract 6667: Pan-cancer assessment of tumour and peripheral T-cell receptor repertoire dynamics in patients treated with immune checkpoint inhibitors)

13. Studies from H. Lee Moffitt Cancer Center and Research Institute Have Provided New Data on Acute Kidney Injury (Outcomes of Cd19-targeted Chimeric Antigen Receptor T Cell Therapy for Patients With Reduced Renal Function Including Dialysis)

14. Research from University of Illinois Urbana-Champaign Reveals New Findings on Glioblastomas (TCR-engineered adoptive cell therapy effectively treats intracranial murine glioblastoma)

15. c-Jun overexpression in CAR T cells induces exhaustion resistance

16. Data on Esophageal Cancer Described by Researchers at Zhengzhou University [Clinical Correlation of Function and Tcr V Beta Diversity of Mage-c2-specific Cd8(+) T Cell Response In Esophageal Cancer]

17. New Lung Cancer Research Reported from Huazhong University of Science and Technology (TRAT1 overexpression delays cancer progression and is associated with immune infiltration in lung adenocarcinoma)

18. Studies from Shenzhen University in the Area of Acute Myeloid Leukemia Described (Decitabine Enhances Targeting of Aml Cells By Ny-eso-1-specific Tcr-t Cells and Promotes the Maintenance of Effector Function and the Memory Phenotype)

19. Evolutionary divergence of HLA class I genotype impacts efficacy of cancer immunotherapy

20. Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer

22. New Cell Therapy Study Findings Have Been Reported by Researchers at Henry Ford Hospital (Demographic Differences Among Patients Treated With Chimeric Antigen Receptor T-cell Therapy In the United States)

23. T cell receptor-targeted immunotherapeutics drive selective in vivo HIV- and CMV-specific T cell expansion in humanized mice

24. Building better CAR-T therapies

28. The role of self-peptides in direct T cell allorecognition

29. CD146 bound to LCK promotes T cell receptor signaling and antitumor immune responses in mice

30. Researchers at Charles University Publish New Data on Immunologic Receptors (Chimeric Antigen Receptor Based Cellular Therapy for Treatment Of T-Cell Malignancies)

31. Data on Adenocarcinoma Detailed by Researchers at Zhongnan Hospital of Wuhan University (Restored CD8+PD-1+ T Cells Facilitate the Response to Anti-PD-1 for Patients With Pancreatic Ductal Adenocarcinoma)

32. BET bromodomain protein inhibition reverses chimeric antigen receptor extinction and reinvigorates exhausted T cells in chronic lymphocytic leukemia

33. Chronic T cell receptor stimulation unmasks NK receptor signaling in peripheral T cell lymphomas via epigenetic reprogramming

34. Targeting the T cell receptor [beta]-chain constant region for immunotherapy of T cell malignancies

35. New Antineoplastics Findings from University of Jinan Described (P Predictive Value of Tcr V Beta-j Beta Profile for Adjuvant Gefitinib In Egfr Mutant Nsclc From Adjuvant-ctong 1104 Trial)

36. Research from Heidelberg University Hospital Has Provided New Study Findings on Molecular Science (Comparison of FACS and PCR for Detection of BCMA-CAR-T Cells)

37. New Findings in Acute Lymphoblastic Leukemia Described from City of Hope National Medical Center (Cd19/baff-r Dual-targeted Car T Cells for the Treatment of Mixed Antigen-negative Variants of Acute Lymphoblastic Leukemia)

38. HLA class I-associated expansion of TRBV11-2 T cells in multisystem inflammatory syndrome in children

39. Functional characterization of [CD4.sup.+] T cell receptors crossreactive for SARS-CoV-2 and endemic coronaviruses

40. Insight into next-generation CAR therapeutics: designing CAR T cells to improve clinical outcomes

41. 25+ Leading TCR Therapy Pipeline Companies are working to improve the Treatment Landscape

42. Public T cell receptors confer high-avidity CD4 responses to HIV controllers

43. Study Findings from Ritsumeikan University Advance Knowledge in Bovine Serum Albumin (Canonical Wnt signaling activation by chimeric antigen receptors for efficient cardiac differentiation from mouse embryonic stem cells)

44. Cytotoxic T lymphocyte antigen-4 and immune checkpoint blockade

45. CAR therapy: the CD19 paradigm

46. Survivin-specific T cell receptor targets tumor but not T cells

47. Research from University of Gothenburg in the Area of Immunoglobulins Published (Single-cell RNA sequencing analyses: interference by the genes that encode the B-cell and T-cell receptors)

48. New Science Study Findings Have Been Reported by Investigators at Georgia Institute of Technology (Cooperative Binding of T Cell Receptor and Cd4 To Peptide-mhc Enhances Antigen Sensitivity)

49. New Machine Learning Study Findings Have Been Reported from Technical University of Denmark (DTU) (NetTCR-2.1: Lessons and guidance on how to develop models for TCR specificity predictions)

50. New Immunologic Receptors Study Findings Reported from Walter and Eliza Hall Institute of Medical Research (T cell and B cell antigen receptors share a conserved core transmembrane structure)

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