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1. Incidence of bacterial and fungal infections in Polish pediatric patients with acute lymphoblastic leukemia during the pandemic

Author

Zawitkowska, Joanna, Drabko, Katarzyna, Lejman, Monika, Kowalczyk, Adrian, Czyżewski, Krzysztof, Dziedzic, Magdalena, Jaremek, Kamila, Zalas-Więcek, Patrycja, Szmydki-Baran, Anna, Hutnik, Łukasz, Czogała, Wojciech, Balwierz, Walentyna, Żak, Iwona, Salamonowicz-Bodzioch, Małgorzata, Kazanowska, Bernarda, Wróbel, Grażyna, Frączkiewicz, Jowita, Kałwak, Krzysztof, Tomaszewska, Renata, Szczepański, Tomasz, Zając-Spychała, Olga, Wachowiak, Jacek, Płonowski, Marcin, Krawczuk-Rybak, Maryna, Królak, Aleksandra, Ociepa, Tomasz, Urasiński, Tomasz, Pierlejewski, Filip, Młynarski, Wojciech, Urbańska-Rakus, Justyna, Machnik, Katarzyna, Pająk, Sonia, Badowska, Wanda, Brzeski, Tomasz, Mycko, Katarzyna, Mańko-Glińska, Hanna, Urbanek-Dądela, Agnieszka, Karolczyk, Grażyna, Mizia-Malarz, Agnieszka, Stolpa, Weronika, Skowron-Kandzia, Katarzyna, Musiał, Jakub, Chaber, Radosław, Irga-Jaworska, Ninela, Bień, Ewa, and Styczyński, Jan

Published
2023
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2. Acute Pancreatitis in Pediatric Acute Lymphoblastic Leukemia (AcuPA Study). A Nationwide Survey in Poland

Author

Morawiak, Anna, primary, Salamonowicz, Małgorzata, additional, Królak, Aleksandra, additional, Kałwak, Krzysztof, additional, Owoc-Lempach, Joanna, additional, Kowalczyk, Jerzy, additional, Zawitkowska, Joanna, additional, Szczepański, Tomasz, additional, Irga-Jaworska, Ninela, additional, Adamkiewicz-Drożyńska, Elżbieta, additional, Albrecht, Katarzyna, additional, Szmydki-Baran, Anna, additional, Balwierz, Walentyna, additional, Czogała, Małgorzata, additional, Wachowiak, Jacek, additional, Derwich, Katarzyna, additional, Młynarski, Wojciech, additional, Zalewska-Szewczyk, Beata, additional, Krawczuk-Rybak, Maryna, additional, Sawicka- Żukowska, Małgorzata, additional, Styczyński, Jan, additional, Kołtan, Andrzej, additional, Safranow, Krzysztof, additional, Urasiński, Tomasz, additional, and Ociepa, Tomasz, additional

Published
2024
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3. Correction to: COVID-19 in pediatric cancer patients is associated with treatment interruptions but not with short-term mortality: a Polish national study

Author

Węcławek-Tompol, Jadwiga, Zakrzewska, Zuzanna, Gryniewicz-Kwiatkowska, Olga, Pierlejewski, Filip, Bień, Ewa, Zaucha-Prażmo, Agnieszka, Zając-Spychała, Olga, Szmydki-Baran, Anna, Mizia-Malarz, Agnieszka, Bal, Wioletta, Sawicka-Żukowska, Małgorzata, Kruk, Agnieszka, Ociepa, Tomasz, Raciborska, Anna, Książek, Agnieszka, Szczepański, Tomasz, Peregud-Pogorzelski, Jarosław, Krawczuk-Rybak, Maryna, Chaber, Radosław, Matysiak, Michał, Wachowiak, Jacek, Irga-Jaworska, Ninela, Młynarski, Wojciech, Dembowska-Bagińska, Bożenna, Balwierz, Walentyna, Matkowska-Kocjan, Agnieszka, Kazanowska, Bernarda, Styczyński, Jan, and Ussowicz, Marek

Published
2022
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4. Acute Pancreatitis in Pediatric Acute Lymphoblastic Leukemia (AcuPA Study): A Nationwide Survey in Poland.

Author

Morawiak, Anna, Salamonowicz-Bodzioch, Małgorzata, Królak, Aleksandra, Kałwak, Krzysztof, Owoc-Lempach, Joanna, Kowalczyk, Jerzy, Zawitkowska, Joanna, Szczepański, Tomasz, Irga-Jaworska, Ninela, Adamkiewicz-Drożyńska, Elżbieta, Albrecht, Katarzyna, Szmydki-Baran, Anna, Balwierz, Walentyna, Czogała, Małgorzata, Wachowiak, Jacek, Derwich, Katarzyna, Młynarski, Wojciech, Zalewska-Szewczyk, Beata, Krawczuk-Rybak, Maryna, and Sawicka-Żukowska, Małgorzata

Subjects
RISK assessment, HEALTH impact assessment, DESCRIPTIVE statistics, PANCREATITIS, CANCER chemotherapy, ODDS ratio, ASPARAGINASE, LYMPHOBLASTIC leukemia, COMPARATIVE studies, CONFIDENCE intervals, PROGRESSION-free survival, DISEASE risk factors, DISEASE complications, CHILDREN
Abstract

Simple Summary: Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy. Survival rates for children with ALL have improved, and today, more than 90% of children with ALL can be successfully treated. Acute pancreatitis (AP), which develops during chemotherapy for ALL can be a serious and fatal complication. It is a widely known toxicity, and several reports indicate that AP occurs with an incidence of 2–10% in patients treated for leukemia. It is mainly, but not exclusively, associated with the administration of asparaginase (ASP), which is one of the key components of multiagent chemotherapy used in ALL. The development of AP usually delays subsequent courses of chemotherapy and is the most common reason for the discontinuation of ASP, thus increasing the potential risk of leukemia relapse in children with ALL. Therefore, both the pathogenesis of AP in ALL and its impact on long-term outcomes remain to be thoroughly investigated. Purpose: This study aimed to identify the risk factors for acute pancreatitis (AP) and its impact on outcomes in Polish children treated for ALL. Methods: The study group included 2303 children receiving intensive chemotherapy for ALL. The group was divided into patients with at least one episode of AP and those who did not develop AP after treatment for ALL. Results: The cumulative incidence of AP in the study group was 4.08%. Older age was an independent risk factor for the development of AP (OR = 1.05; 95%CI = 1.006–1.098; p = 0.03). The overall mortality associated with AP was 2.13%. The probabilities of disease-free survival (p-DFS) and event-free survival (p-EFS) in both subgroups were 0.84 vs. 0.86, log-rank p = 0.65 and 0.75 vs. 0.80, log-rank p = 0.12, respectively. A total of 22 out of 94 patients (23.4%) with AP were re-exposed to asparaginase (ASP) during the subsequent treatment phases. Only one patient re-exposed to ASP (4.5%) developed a second episode of AP. There were no significant differences in p-DFS and p-EFS between patients re-exposed and not re-exposed to asparaginase (0.78 vs. 0.86, log-rank p = 0.27 and 0.63 vs. 0.79, log-rank p = 0.09, respectively). Conclusions: The incidence of AP in children with ALL is low and related to patients' age. The development of AP does not seem to influence p-DFS and p-EFS in children with ALL. Recurrence of AP after re-exposure to asparaginase in patients with ALL and a history of AP is low (4.5%). Re-exposure to asparaginase after the first episode of AP does not improve either p-DFS or p-EFS in children with ALL. [ABSTRACT FROM AUTHOR]

Published
2024
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5. Infections with Klebsiella pneumoniae in Children Undergoing Anticancer Therapy or Hematopoietic Cell Transplantation: A Multicenter Nationwide Study.

Author

Sękowska, Alicja, Czyżewski, Krzysztof, Jaremek, Kamila, Zalas-Więcek, Patrycja, Zając-Spychała, Olga, Wachowiak, Jacek, Szmydki-Baran, Anna, Hutnik, Łukasz, Gietka, Agnieszka, Gryniewicz-Kwiatkowska, Olga, Dembowska-Bagińska, Bożenna, Semczuk, Katarzyna, Dzierżanowska-Fangrat, Katarzyna, Czogała, Wojciech, Balwierz, Walentyna, Żak, Iwona, Tomaszewska, Renata, Szczepański, Tomasz, Bień, Ewa, and Irga-Jaworska, Ninela

Subjects
HEMATOPOIETIC stem cell transplantation, CHILD patients, URINARY tract infections, CANCER patients, KLEBSIELLA pneumoniae, KLEBSIELLA infections
Abstract

Background: Klebsiella pneumoniae is a nosocomial pathogen that causes severe infections in immunocompromised patients. The aim of the study was to conduct a microbiological and clinical analysis of K. pneumoniae infections in children with malignancies or undergoing hematopoietic cell transplantation in Poland. Methods: We conducted a retrospective, multicenter study including children and adolescents under 19 years old treated between 2012 and 2021. We analyzed patients' characteristics, microbiological data, and the outcomes of antibiotic therapy. Results: A total of 9121 newly diagnosed children were treated for malignancy and 1697 pediatric patients underwent hematopoietic cell transplantation. K. pneumoniae infections were diagnosed in 527 patients. Their overall incidence was 4.86% in pediatric hematology and oncology patients and 4.95% in patients who underwent hematopoietic cell transplantation. The incidence of infection was higher in patients with acute leukemia than with solid tumors (7.8% vs. 4.1%; OR = 2.0; 95% CI = 1.6–2.4; p < 0.0001). The most frequent source of infection was in the urinary tract at 55.2%. More than 57% of K. pneumoniae strains were extended-spectrum β-lactamase-positive and almost 34% were multidrug-resistant. Infections with K. pneumoniae contributed to death in 3.22% of patients. Conclusions: K. pneumoniae is one of the most critical pathogens in children suffering from malignancies or undergoing hematopoietic cell transplantation. The incidence of multidrug-resistant K. pneumoniae strains is increasing and contributing to poor clinical outcome. [ABSTRACT FROM AUTHOR]

Published
2024
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6. Infections With Stenotrophomonas maltophilia in Children Undergoing Anticancer Therapy or Hematopoietic Cell Transplantation: A Multicenter Nationwide Study

Author

Richert-Przygonska, Monika, Czyzewski, Krzysztof, Dziedzic, Magdalena, Zalas-Wiecek, Patrycja, Gryniewicz-Kwiatkowska, Olga, Gietka, Agnieszka, Malas, Zofia, Semczuk, Katarzyna, Chelmecka, Liliana, Zak, Iwona, Salamonowicz-Bodzioch, Malgorzata, Fraczkiewicz, Jowita, Zajac-Spychala, Olga, Bien, Ewa, Irga-Jaworska, Ninela, Plonowski, Marcin, Wawrykow, Pawel, Bartnik, Magdalena, Pierlejewski, Filip, Gamrot, Zuzanna, Badowska, Wanda, Stolpa, Weronika, Musial, Jakub, Szmydki-Baran, Anna, Hutnik, Lukasz, Tomaszewska, Renata, Urbanek-Dadela, Agnieszka, Zaucha-Prazmo, Agnieszka, Gozdzik, Jolanta, and Styczynski, Jan

Published
2022
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7. COVID-19 in pediatric cancer patients is associated with treatment interruptions but not with short-term mortality: a Polish national study

Author

Węcławek-Tompol, Jadwiga, Zakrzewska, Zuzanna, Gryniewicz-Kwiatkowska, Olga, Pierlejewski, Filip, Bień, Ewa, Zaucha-Prażmo, Agnieszka, Zając-Spychała, Olga, Szmydki-Baran, Anna, Mizia-Malarz, Agnieszka, Bal, Wioletta, Sawicka-Żukowska, Małgorzata, Kruk, Agnieszka, Ociepa, Tomasz, Raciborska, Anna, Książek, Agnieszka, Szczepański, Tomasz, Peregud-Pogorzelski, Jarosław, Krawczuk-Rybak, Maryna, Chaber, Radosław, Matysiak, Michał, Wachowiak, Jacek, Irga-Jaworska, Ninela, Młynarski, Wojciech, Dembowska-Bagińska, Bożenna, Balwierz, Walentyna, Matkowska-Kocjan, Agnieszka, Kazanowska, Bernarda, Styczyński, Jan, and Ussowicz, Marek

Published
2021
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8. Infectious profile in children with ALL during chemotherapy: A report of study group for infections

Author

Zawitkowska, Joanna, Drabko, Katarzyna, Szmydki-Baran, Anna, Zaucha-Prażmo, Agnieszka, Lejman, Monika, Czyżewski, Krzysztof, Zalas-Więcek, Patrycja, Gryniewicz–Kwiatkowska, Olga, Czajńska-Deptuła, Aneta, Kulicka, Elwira, Semczuk, Katarzyna, Hutnik, Łukasz, Chełmecka-Wiktorczyk, Liliana, Klepacka, Joanna, Frączkiewicz, Jowita, Salamonowicz, Małgorzata, Tomaszewska, Renata, Zając-Spychała, Olga, Irga-Jaworska, Ninela, Bień, Ewa, Płonowski, Marcin, Bartnik, Magdalena, Ociepa, Tomasz, Pierlejewski, Filip, Woszczyk, Mariola, Gamrot-Pyka, Zuzanna, Małas, Zofia, Urbanek-Dądela, Agnieszka, Stolpa, Weronika, Musiał, Jakub, and Styczyński, Jan

Published
2019
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9. Viral Infection Profile in Children Treated for Acute Lymphoblastic Leukemia—Results of Nationwide Study

Author

Zawitkowska, Joanna, primary, Drabko, Katarzyna, additional, Czyżewski, Krzysztof, additional, Dziedzic, Magdalena, additional, Jaremek, Kamila, additional, Zalas-Więcek, Patrycja, additional, Szmydki-Baran, Anna, additional, Hutnik, Łukasz, additional, Matysiak, Michał, additional, Czogała, Wojciech, additional, Balwierz, Walentyna, additional, Żak, Iwona, additional, Salamonowicz-Bodzioch, Małgorzata, additional, Kazanowska, Bernarda, additional, Wróbel, Grażyna, additional, Kałwak, Krzysztof, additional, Tomaszewska, Renata, additional, Szczepański, Tomasz, additional, Zając-Spychała, Olga, additional, Wachowiak, Jacek, additional, Płonowski, Marcin, additional, Krawczuk-Rybak, Maryna, additional, Królak, Aleksandra, additional, Ociepa, Tomasz, additional, Urasiński, Tomasz, additional, Pierlejewski, Filip, additional, Młynarski, Wojciech, additional, Urbańska-Rakus, Justyna, additional, Machnik, Katarzyna, additional, Pająk, Sonia, additional, Badowska, Wanda, additional, Brzeski, Tomasz, additional, Mycko, Katarzyna, additional, Mańko-Glińska, Hanna, additional, Urbanek-Dądela, Agnieszka, additional, Karolczyk, Grażyna, additional, Mizia-Malarz, Agnieszka, additional, Stolpa, Weronika, additional, Skowron-Kandzia, Katarzyna, additional, Musiał, Jakub, additional, Chaber, Radosław, additional, Irga-Jaworska, Ninela, additional, Bień, Ewa, additional, and Styczyński, Jan, additional

Published
2022
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10. Case report: Successful allogeneic stem cell transplantation in a child with novel GATA2 defect associated B-cell acute lymphoblastic leukemia

Author

Heropolitańska-Pliszka, Edyta, primary, Piątosa, Barbara, additional, Szmydki-Baran, Anna, additional, Kuczborska, Karolina, additional, Miarka-Walczyk, Karolina, additional, Pastorczak, Agata, additional, Młynarski, Wojciech, additional, Sędek, Łukasz, additional, Szczepański, Tomasz, additional, and Ussowicz, Marek, additional

Published
2022
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11. Clinical Characteristics and Treatment Outcomes of Myeloid Sarcoma in Children: The Experience of the Polish Pediatric Leukemia and Lymphoma Study Group

Author

Samborska, Magdalena, primary, Barańska, Małgorzata, additional, Wachowiak, Jacek, additional, Skalska-Sadowska, Jolanta, additional, Thambyrajah, Sheanda, additional, Czogała, Małgorzata, additional, Balwierz, Walentyna, additional, Kołtan, Sylwia, additional, Peszyńska-Żelazny, Katarzyna, additional, Wysocki, Mariusz, additional, Ociepa, Tomasz, additional, Urasiński, Tomasz, additional, Wróbel, Grażyna, additional, Węcławek-Tompol, Jadwiga, additional, Ukielska, Bogna, additional, Chybicka, Alicja, additional, Kitszel, Anna, additional, Krawczuk-Rybak, Maryna, additional, Szmydki-Baran, Anna, additional, Malinowska, Iwona, additional, Matysiak, Michał, additional, Mizia-Malarz, Agnieszka, additional, Tomaszewska, Renata, additional, Szczepański, Tomasz, additional, Chodała-Grzywacz, Agnieszka, additional, Karolczyk, Grażyna, additional, Maciejka-Kembłowska, Lucyna, additional, Irga-Jaworska, Ninela, additional, Badowska, Wanda, additional, Dopierała, Michał, additional, Kurzawa, Paweł, additional, and Derwich, Katarzyna, additional

Published
2022
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12. Severe thalassemia alpha diagnosed and prenatally treated in Poland: clinical follow-up of case with more than one hematological disease.

Author

Szmydki-Baran, Anna, Cieślak, Mariusz, Mielcarek-Siedziuk, Monika, Kałwak, Krzysztof, and Łaguna, Paweł

Abstract

The article presents a case study of a patient with severe thalassemia alpha and concomitant hydrops fetalis, who underwent prenatal treatment and subsequent hematopoietic stem cell transplantation Topics include the successful management of severe thalassemia alpha with prenatal interventions and the unique occurrence of acute lymphoblastic leukemia as a secondary hematological disease in this patient, leading to a discussion of hematopoietic stem cell transplantation as a treatment option.

Published
2023
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14. Przydatność cytometrycznej analizy białek cytoszkieletu i błon erytrocytów (test EMA) w diagnozowaniu wrodzonych niedokrwistości hemolitycznych u dzieci

Author

Adamowicz-Salach, Anna, Szmydki-Baran, Anna, Gołębiowska-Staroszczyk, Sydonia, Sobocińska-Mirska, Agata, Matysiak, Michał, Albrecht-Stanisławska, Katarzyna, Romiszewski, Michał, Niewiadomska, Edyta, Ciebiera, Małgorzata, Zdebska, Ewa, Spychalska, Justyna, Smoleńska-Sym, Gabriela, and Siwicka, Alicja

Published
2009
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15. Additional file 1 of COVID-19 in pediatric cancer patients is associated with treatment interruptions but not with short-term mortality: a Polish national study

Author

Węcławek-Tompol, Jadwiga, Zakrzewska, Zuzanna, Gryniewicz-Kwiatkowska, Olga, Pierlejewski, Filip, Bień, Ewa, Zaucha-Prażmo, Agnieszka, Zając-Spychała, Olga, Szmydki-Baran, Anna, Mizia-Malarz, Agnieszka, Bal, Wioletta, Sawicka-Żukowska, Małgorzata, Kruk, Agnieszka, Raciborska, Anna, Książek, Agnieszka, Szczepański, Tomasz, Peregud-Pogorzelski, Jarosław, Krawczuk-Rybak, Maryna, Chaber, Radosław, Matysiak, Michał, Wachowiak, Jacek, Młynarski, Wojciech, Dembowska-Bagińska, Bożenna, Balwierz, Walentyna, Matkowska-Kocjan, Agnieszka, Kazanowska, Bernarda, Styczyński, Jan, and Ussowicz, Marek

Subjects
Data_FILES, GeneralLiterature_REFERENCE(e.g.,dictionaries,encyclopedias,glossaries)
Abstract

Additional file 1. List of chemotherapy protocols.

Published
2021
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26. Infections With Stenotrophomonas maltophiliain Children Undergoing Anticancer Therapy or Hematopoietic Cell Transplantation: A Multicenter Nationwide Study

Author

Richert-Przygonska, Monika, Czyzewski, Krzysztof, Dziedzic, Magdalena, Zalas-Wiecek, Patrycja, Gryniewicz-Kwiatkowska, Olga, Gietka, Agnieszka, Malas, Zofia, Semczuk, Katarzyna, Chelmecka, Liliana, Zak, Iwona, Salamonowicz-Bodzioch, Malgorzata, Fraczkiewicz, Jowita, Zajac-Spychala, Olga, Bien, Ewa, Irga-Jaworska, Ninela, Plonowski, Marcin, Wawrykow, Pawel, Bartnik, Magdalena, Pierlejewski, Filip, Gamrot, Zuzanna, Badowska, Wanda, Stolpa, Weronika, Musial, Jakub, Szmydki-Baran, Anna, Hutnik, Lukasz, Tomaszewska, Renata, Urbanek-Dadela, Agnieszka, Zaucha-Prazmo, Agnieszka, Gozdzik, Jolanta, and Styczynski, Jan

Published
2022
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27. Prevalence, Epidemiology, Etiology, and Sensitivity of Invasive Bacterial Infections in Pediatric Patients Undergoing Oncological Treatment: A Multicenter Nationwide Study

Author

Zajac-Spychala, Olga, primary, Wachowiak, Jacek, additional, Gryniewicz–Kwiatkowska, Olga, additional, Gietka, Aneta, additional, Dembowska-Baginska, Bozenna, additional, Semczuk, Katarzyna, additional, Dzierzanowska-Fangrat, Katarzyna, additional, Czyzewski, Krzysztof, additional, Dziedzic, Magdalena, additional, Wysocki, Mariusz, additional, Zalas-Wiecek, Patrycja, additional, Szmydki-Baran, Anna, additional, Hutnik, Lukasz, additional, Matysiak, Michal, additional, Pierlejewski, Filip, additional, Mlynarski, Wojciech, additional, Małas, Zofia, additional, Badowska, Wanda, additional, Irga-Jaworska, Ninela, additional, Bien, Ewa, additional, Drozynska, Elzbieta, additional, Bartnik, Magdalena, additional, Ociepa, Tomasz, additional, Urasiński, Tomasz, additional, Wawrykow, Pawel, additional, Peregud-Pogorzelski, Jaroslaw, additional, Stolpa, Weronika, additional, Sobol-Milejska, Grazyna, additional, Fraczkiewicz, Jowita, additional, Salamonowicz, Malgorzata, additional, Kazanowska, Bernarda, additional, Chybicka, Alicja, additional, Chelmecka-Wiktorczyk, Liliana, additional, Balwierz, Walentyna, additional, Zak, Iwona, additional, Gamrot-Pyka, Zuzanna, additional, Woszczyk, Mariola, additional, Tomaszewska, Renata, additional, Szczepanski, Tomasz, additional, Plonowski, Marcin, additional, Krawczuk-Rybak, Maryna, additional, Urbanek-Dadela, Agnieszka, additional, Karolczyk, Grazyna, additional, Musial, Jakub, additional, Chaber, Radoslaw, additional, Kowalczyk, Jerzy, additional, and Styczynski, Jan, additional

Published
2021
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29. Varicella‐zoster virus infection in the pediatric population with acute lymphoblastic leukemia in Poland

Author

Zawitkowska, Joanna, primary, Lejman, Monika, additional, Szmydki‐Baran, Anna, additional, Zaucha‐Prażmo, Agnieszka, additional, Czyżewski, Krzysztof, additional, Dziedzic, Magdalena, additional, Zalas‐Więcek, Patrycja, additional, Gryniewicz–Kwiatkowska, Olga, additional, Czajńska‐Deptuła, Aneta, additional, Gietka, Agnieszka, additional, Semczuk, Katarzyna, additional, Hutnik, Łukasz, additional, Chełmecka‐Wiktorczyk, Liliana, additional, Żak, Iwona, additional, Frączkiewicz, Jowita, additional, Salamonowicz, Małgorzata, additional, Tomaszewska, Renata, additional, Zając‐Spychała, Olga, additional, Irga‐Jaworska, Ninela, additional, Bień, Ewa, additional, Płonowski, Marcin, additional, Bartnik, Magdalena, additional, Ociepa, Tomasz, additional, Pierlejewski, Filip, additional, Machnik, Katarzyna, additional, Gamrot‐Pyka, Zuzanna, additional, Badowska, Wanda, additional, Brzeski, Tomasz, additional, Urbanek‐Dądela, Agnieszka, additional, Stolpa, Weronika, additional, Mizia‐Malarz, Agnieszka, additional, Skowron‐Kandzia, Katarzyna, additional, Musiał, Jakub, additional, and Styczyński, Jan, additional

Published
2020
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30. Epidemiology and outcome of invasive fungal disease in children after hematopoietic cell transplantation or treated for malignancy: Impact of national programme of antifungal prophylaxis

Author

Czyżewski, Krzysztof, primary, Gałązka, Przemysław, additional, Frączkiewicz, Jowita, additional, Salamonowicz, Małgorzata, additional, Szmydki‐Baran, Anna, additional, Zając‐Spychała, Olga, additional, Gryniewicz‐Kwiatkowska, Olga, additional, Zalas‐Więcek, Patrycja, additional, Chełmecka‐Wiktorczyk, Liliana, additional, Irga‐Jaworska, Ninela, additional, Bień, Ewa, additional, Ociepa, Tomasz, additional, Wawryków, Paweł, additional, Tomaszewska, Renata, additional, Płonowski, Marcin, additional, Pierlejewski, Filip, additional, Gamrot‐Pyka, Zuzanna, additional, Małas, Zofia, additional, Urbanek‐Dądela, Agnieszka, additional, Stolpa, Weronika, additional, Zaucha‐Prażmo, Agnieszka, additional, Goździk, Jolanta, additional, Chaber, Radosław, additional, Gil, Lidia, additional, and Styczyński, Jan, additional

Published
2019
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31. Infections in children with acute myeloid leukemia: increased mortality in relapsed/refractory patients

Author

Zając-Spychała, Olga, primary, Skalska-Sadowska, Jolanta, additional, Wachowiak, Jacek, additional, Szmydki-Baran, Anna, additional, Hutnik, Łukasz, additional, Matysiak, Michał, additional, Pierlejewski, Filip, additional, Młynarski, Wojciech, additional, Czyżewski, Krzysztof, additional, Dziedzic, Magdalena, additional, Wysocki, Mariusz, additional, Zalas-Więcek, Patrycja, additional, Bartnik, Magdalena, additional, Ociepa, Tomasz, additional, Urasiński, Tomasz, additional, Małas, Zofia, additional, Badowska, Wanda, additional, Gamrot-Pyka, Zuzanna, additional, Woszczyk, Mariola, additional, Tomaszewska, Renata, additional, Szczepański, Tomasz, additional, Irga-Jaworska, Nina, additional, Drożyńska, Elżbieta, additional, Urbanek-Dądela, Agnieszka, additional, Karolczyk, Grażyna, additional, Płonowski, Marcin, additional, Krawczuk-Rybak, Maryna, additional, Frączkiewicz, Jowita, additional, Salamonowicz, Malgorzata, additional, Chybicka, Alicja, additional, Stolpa, Weronika, additional, Sobol-Milejska, Grazyna, additional, Chełmecka-Wiktorczyk, Liliana, additional, Balwierz, Walentyna, additional, Zak, Iwona, additional, Gryniewicz–Kwiatkowska, Olga, additional, Gietka, Aneta, additional, Dembowska-Bagińska, Bozenna, additional, Semczuk, Katarzyna, additional, Dzierżanowska-Fangrat, Katarzyna, additional, Musiał, Jakub, additional, Chaber, Radoslaw, additional, Kowalczyk, Jerzy, additional, and Styczyński, Jan, additional

Published
2019
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32. Infectious complications in children treated for hodgkin and non-hodgkin lymphomas in polish pediatric leukemia/lymphoma study group: incidence, epidemiology and etiology

Author

Zajac-Spychala, Olga, primary, Wachowiak, Jacek, additional, Szmydki-Baran, Anna, additional, Hutnik, Lukasz, additional, Salamonowicz, Malgorzata, additional, Matysiak, Michal, additional, Czyzewski, Krzysztof, additional, Wysocki, Mariusz, additional, Zalas-Wiecek, Patrycja, additional, Malas, Zofia, additional, Badowska, Wanda, additional, Gryniewicz-Kwiatkowska, Olga, additional, Czajnska-Deptuła, Aneta, additional, Kulicka, Elwira, additional, Dembowska-Baginska, Bozenna, additional, Perek, Danuta, additional, Semczuk, Katarzyna, additional, Dzierzanowska-Fangrat, Katarzyna, additional, Ociepa, Tomasz, additional, Bartnik, Magdalena, additional, Chelmecka-Wiktorczyk, Liliana, additional, Balwierz, Walentyna, additional, Klepacka, Joanna, additional, Irga-Jaworska, Nina, additional, Bien, Ewa, additional, Adamkiewicz-Drozynska, Elzbieta, additional, Urbanek-Dadela, Agnieszka, additional, Karolczyk, Grazyna, additional, Pierlejewski, Filip, additional, Mlynarski, Wojciech, additional, Plonowski, Marcin, additional, Krawczuk-Rybak, Maryna, additional, Stolpa, Weronika, additional, Sobol, Grazyna, additional, Tomaszewska, Renata, additional, Szczepanski, Tomasz, additional, Gamrot, Zuzanna, additional, Woszczyk, Mariola, additional, Wieczorek, Maria, additional, Kowalczyk, Jerzy, additional, and Styczynski, Jan, additional

Published
2018
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33. Epidemiological analysis of staphylococci infections in patients treated for malignancy or undergoing stem cell transplant : update report 2016

Author

Styczyński, Jan, Czyżewski, Krzysztof, Zalas-Więcek, Patrycja, Pogorzała, Monika, Dziedzic, Magdalena, Gryniewicz-Kwiatkowska, Olga, Czajńska-Deptuła, Aneta, Kulicka, Elwira, Dembowska-Bagińska, Bożenna, Semczuk, Katarzyna, Dzierżanowska-Fangrat, Katarzyna, Szmydki-Baran, Anna, Hutnik, Łukasz, Matysiak, Michał, Chełmecka-Wiktorczyk, Liliana, Balwierz, Walentyna, Klepacka, Joanna, Tomaszewska, Renata, Szczepański, Tomasz, Zając-Spychała, Olga, Wachowiak, Jacek, Irga-Jaworska, Ninela, Bień, Ewa, Drożyńska, Elżbieta, Płonowski, Marcin, Krawczuk-Rybak, Maryna, Ociepa, Tomasz, Bartnik, Magdalena, Wawryków, Paweł, Pierlejewski, Filip, Młynarski, Wojciech Michał, Gamrot-Pyka, Zuzanna, Woszczyk, Mariola, Małas, Zofia, Badowska, Wanda, Urbanek-Dądela, Agnieszka, Karolczyk, Grażyna, Stolpa, Weronika, Sobol-Milejska, Grażyna, Zaucha-Prażmo, Agnieszka, Kowalczyk, Jerzy R., Goździk, Jolanta, Frączkiewicz, Jowita, Salamonowicz, Małgorzata, Gorczyńska, Ewa, Kałwak, Krzysztof, Chybicka, Alicja, Gospodarek-Komkowska, Eugenia, and Wysocki, Mariusz

Subjects
children, dzieci, choroby nowotworowe, gronkowiec, staphylococcus, stem cell transplantation, przeszczepianie komórek krwiotwórczych, malignant diseases
Published
2016

34. Profil zakażeń w polskich pediatrycznych ośrodkach hematologii, onkologii i przeszczepiania komórek krwiotwórczych w latach 2014-2015

Author

Styczyński, Jan, Czyżewski, Krzysztof, Zalas-Więcek, Patrycja, Gryniewicz-Kwiatkowska, Olga, Czajńska-Deptuła, Aneta, Kulicka, Elwira, Dembowska-Bagińska, Bożenna, Semczuk, Katarzyna, Dzierżanowska-Fangrat, Katarzyna, Szmydki-Baran, Anna, Hutnik, Łukasz, Matysiak, Michał, Chełmecka-Wiktorczyk, Liliana, Balwierz, Walentyna, Klepacka, Joanna, Tomaszewska, Renata, Szczepański, Tomasz, Zając-Spychała, Olga, Wachowiak, Jacek, Irga-Jaworska, Ninela, Bień, Ewa, Drożyńska, Elżbieta, Płonowski, Marcin, Krawczuk-Rybak, Maryna, Ociepa, Tomasz, Bartnik, Magdalena, Wawryków, Paweł, Pierlejewski, Filip, Młynarski, Wojciech Michał, Gamrot-Pyka, Zuzanna, Woszczyk, Mariola, Małas, Zofia, Badowska, Wanda, Urbanek-Dądela, Agnieszka, Karolczyk, Grażyna, Stolpa, Weronika, Sobol-Milejska, Grażyna, Zaucha-Prażmo, Agnieszka, Kowalczyk, Jerzy R., Goździk, Jolanta, Frączkiewicz, Jowita, Salamonowicz, Małgorzata, Gorczyńska, Ewa, Kałwak, Krzysztof, Chybicka, Alicja, Dziedzic, Magdalena, Gospodarek-Komkowska, Eugenia, and Wysocki, Mariusz

Subjects
onkohematologia, invasive fungal infections, dzieci, viral infections, zakażenia wirusowe, choroby nowotworowe, oncohematology, przeszczepianie komórek krwiotwórczych, bacterial infections, children, hematopoietic stem cell transplantation, zakażenia bakteryjne, inwazyjne zakażenia grzybicze, malignant diseases
Published
2016

35. Efficacy of micafungin in empirical, preemptive and targeted therapy of invasive fungal disease in children with malignancy or undergoing stem cell transplantation

Author

Styczyński, Jan, Czyżewski, Krzysztof, Zalas-Więcek, Patrycja, Gryniewicz-Kwiatkowska, Olga, Czajńska-Deptuła, Aneta, Kulicka, Elwira, Dembowska-Bagińska, Bożenna, Semczuk, Katarzyna, Dzierżanowska-Fangrat, Katarzyna, Szmydki-Baran, Anna, Hutnik, Łukasz, Matysiak, Michał, Chełmecka-Wiktorczyk, Liliana, Balwierz, Walentyna, Klepacka, Joanna, Tomaszewska, Renata, Szczepański, Tomasz, Zając-Spychała, Olga, Wachowiak, Jacek, Irga-Jaworska, Ninela, Bień, Ewa, Drożyńska, Elżbieta, Płonowski, Marcin, Krawczuk-Rybak, Maryna, Ociepa, Tomasz, Bartnik, Magdalena, Wawryków, Paweł, Pierlejewski, Filip, Młynarski, Wojciech Michał, Gamrot-Pyka, Zuzanna, Woszczyk, Mariola, Małas, Zofia, Badowska, Wanda, Urbanek-Dądela, Agnieszka, Karolczyk, Grażyna, Stolpa, Weronika, Sobol-Milejska, Grażyna, Zaucha-Prażmo, Agnieszka, Kowalczyk, Jerzy R., Goździk, Jolanta, Frączkiewicz, Jowita, Salomonowicz, Małgorzata, Gorczyńska, Ewa, Kałwak, Krzysztof, Chybicka, Alicja, Gospodarek-Komkowska, Eugenia, Pogorzała, Monika, and Wysocki, Mariusz

Published
2016

36. Infectious complications in children treated for hodgkin and non-hodgkin lymphomas in polish pediatric leukemia/lymphoma study group: incidence, epidemiology and etiology.

Author

Zajac-Spychala, Olga, Wachowiak, Jacek, Szmydki-Baran, Anna, Hutnik, Lukasz, Salamonowicz, Malgorzata, Matysiak, Michal, Czyzewski, Krzysztof, Wysocki, Mariusz, Zalas-Wiecek, Patrycja, Malas, Zofia, Badowska, Wanda, Gryniewicz-Kwiatkowska, Olga, Czajnska-Deptuła, Aneta, Kulicka, Elwira, Dembowska-Baginska, Bozenna, Perek, Danuta, Semczuk, Katarzyna, Dzierzanowska-Fangrat, Katarzyna, Ociepa, Tomasz, and Bartnik, Magdalena

Subjects
EPIDEMIOLOGY, CHILDREN
Abstract

The objective of this nation-wide study was to evaluate the epidemiology and profile of bacterial (BI), viral (VI), and invasive fungal disease (IFD) in patients treated for non-Hodgkin lymphoma (NHL) and Hodgkin lymphoma (HL) between the years 2013-2015. In the analyzed period of time, within the studied group of 328 children diagnosed and treated for lymphomas, at least one infectious complication (IC) was diagnosed i.e. 39.3% children. In these patients there were 350 episodes of IC, therein 80.6% episodes of BI, 11.1% episodes of VI, and 8.3% episodes of IFD. In both groups, NHL and HL patients, a stable level of bacterial infections, with an increase in resistance rates, and increased levels of viral and fungal infections were observed. Profile of BI does not depend on lymphoma type, with predominance of Gram-negative bacteria and higher prevalence of MDR pathogens. The overall survival of lymphoma patients with IC was comparable for different types of infections. [ABSTRACT FROM AUTHOR]

Published
2019
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38. SKUTECZNOŚĆ MYKAFUNGINY W EMPIRYCZNEJ, WYPRZEDZAJĄCEJ I CELOWANEJ TERAPII INWAZYJNEJ CHOROBY GRZYBICZEJ U DZIECI Z CHOROBAMI NOWOTWOROWYMI LUB PODDAWANYCH PRZESZCZEPIENIU KOMÓREK KRWIOTWÓRCZYCH.

Author

STYCZYŃSKI, JAN, CZYŻEWSKI, KRZYSZTOF, ZALAS-WIĘCEK, PATRYCJA, GRYNIEWICZ-KWIATKOWSKA, OLGA, CZAJŃSKA-DEPTUŁA, ANETA, KULICKA, ELWIRA, DEMBOWSKA-BAGIŃSKA, BOŻENNA, SEMCZUK, KATARZYNA, DZIERŻANOWSKA-FANGRAT, KATARZYNA, SZMYDKI-BARAN, ANNA, HUTNIK, ŁUKASZ, MATYSIAK, MICHAŁ, CHEŁMECKA-WIKTORCZYK, LILIANA, BALWIERZ, WALENTYNA, KLEPACKA, JOANNA, TOMASZEWSKA, RENATA, SZCZEPAŃSKI, TOMASZ, ZAJĄC-SPYCHAŁA, OLGA, WACHOWIAK, JACEK, and IRGA-JAWORSKA, NINELA

Abstract

Copyright of Forum Zakażeń is the property of Evereth Publishing Ltd. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2016
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39. Zakażenia wirusem SARS-CoV-2 u dzieci leczonych z powodu choroby nowotworowej lub poddanych transplantacji komórek krwiotwórczych w Polsce ― raport Grupy ds. Zakażeń Polskiego Towarzystwa Onkologii i Hematologii Dziecięcej

Author

Zając-Spychała, Olga, Czyżewski, Krzysztof, Wachowiak, Jacek, Dziedzic, Magdalena, Jaremek, Kamila, Wysocki, Mariusz, Zalas-Więcek, Patrycja, Salamonowicz-Bodzioch, Małgorzata, Frączkiewicz, Jowita, Ussowicz, Marek, Kałwak, Krzysztof, Bień, Ewa, Irga-Jaworska, Ninela, Pierlejewski, Filip, Młynarski, Wojciech, Szmydki-Baran, Anna, Hutnik, Łukasz, Matysiak, Michał, Stolpa, Weronika, and Skowron-Kandzia, Katarzyna

Abstract

Copyright of Acta Haematologica Polonica is the property of VM Medica-VM Group (Via Medica) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2022

40. [Erythropoietin treatment of infants with anaemia in the first three months of life].

Author

Gołebiowska-Staroszczyk S, Matysiak M, Adamowicz-Salach A, Sobocińska-Mirska A, Szmydki-Baran A, and Romiszewski M

Subjects
Anemia blood, Hemoglobins analysis, Hemoglobins drug effects, Humans, Infant, Infant, Newborn, Infant, Premature, Diseases blood, Injections, Subcutaneous, Recombinant Proteins, Anemia drug therapy, Erythropoietin therapeutic use, Infant, Premature, Diseases drug therapy
Abstract

Unlabelled: Synthesis of recombinant human erythropoietin opened new possibilities for treatment of anaemia in infants., Aim: To assess the safety and effects of this treatment of anaemia in infants., Material and Methods: The study included 111 infants with anaemia aged between 3 and 10 weeks. Children were referred to the One Day Clinic of the Department of Paediatrics, Haematology and Oncology, Warsaw Medical University, by family doctors because of low haemoglobin concentration, in spite of iron supplementation. Patients were divided into two groups: group A - term infants and B - preterm infants. Both these groups were divided according to risk factors: serological incompatibility and infection at birth or just after birth. Recombinant human erythropoietin was given subcutaneously in doses of 500 IU/kg b. w./week. Therapy was ended when haemoglobin concentration reached 11 g/dl., Results: Initial haemoglobin concentration in serum is the main factor which influence the length of recombinant human erythropoietin therapy of anaemia both in preterm and term infants. Serological incompatibility and infection at birth and just after birth lengthen the period of erythropoietin treatment of anaemia in both groups of patients., Conclusions: Recombinant human erythropoietin is an effective and fully safe drug in the treatment of anaemia in the first three months of life, both in preterm and term infants. Its high effectiveness is confirmed by comparative analysis of haematologic parameters in the first trimester of retrospective control group of infants without recombinant human erythropoietin therapy and term infants who had been treated with erythropoietin.

Published
2009

41. [Danazol - effective second line therapy in idiopathic thrombocytopenic purpura in children. Three case reports].

Author

Szmydki-Baran A, Adamowicz-Salach A, and Gołebiowska-Staroszczyk S

Subjects
Child, Female, Humans, Platelet Count, Purpura, Thrombocytopenic, Idiopathic blood, Purpura, Thrombocytopenic, Idiopathic surgery, Splenectomy, Treatment Failure, Danazol therapeutic use, Purpura, Thrombocytopenic, Idiopathic drug therapy
Abstract

Danazol is an accredited second line drug for idiopathic thrombocytopenic purpura (ITP) in adults. There are very few positions in the literature about using danazol in children, although some articles quote its evident efficacy. In this paper we present three cases of children treated with danazol. The routine treatment in these ITP cases was ineffective. The result was stabilization of platelet count and avoidance of splenectomy.

Published
2008

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