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187 results on '"Szewczyk, Magdalena M."'

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1. A chemical probe to modulate human GID4 Pro/N-degron interactions

4. PRMT inhibition induces a viral mimicry response in triple-negative breast cancer

7. A chemical probe targeting the PWWP domain alters NSD2 nucleolar localization

8. Probing CRL4DCAF12 interactions with MAGEA3 and CCT5 di-Glu C-terminal degrons

9. Huntingtin structure is orchestrated by HAP40 and shows a polyglutamine expansion-specific interaction with exon 1

11. Chemical tools for the Gid4 subunit of the human E3 ligase C-terminal to LisH (CTLH) degradation complex

13. Epigenetic vulnerabilities of leukemia harboring inactivating EZH2 mutations

15. Fragment-based discovery of a chemical probe for the PWWP1 domain of NSD3

17. Author Correction: Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response

18. Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response

19. Discovery and Characterization of a Chemical Probe Targeting the Zinc-Finger Ubiquitin-Binding Domain of HDAC6

20. Discovery of a chemical probe for PRDM9

21. Development of HC-258, a Covalent Acrylamide TEAD Inhibitor That Reduces Gene Expression and Cell Migration.

22. Discovery of Nanomolar DCAF1 Small Molecule Ligands

23. A chemical probe to modulate human GID4 Pro/N-degron interactions

24. Chemical tools for the Gid4 subunit of the human E3 ligase C-terminal to LisH (CTLH) degradation complexElectronic supplementary information (ESI) available. See DOI: https://doi.org/10.1039/d3md00633f

29. A chemical probe targeting the PWWP domain alters NSD2 nucleolar localization

31. Development of LM98, a Small‐Molecule TEAD Inhibitor Derived from Flufenamic Acid

33. Huntingtin structure is orchestrated by HAP40 and shows a polyglutamine expansion-specific interaction with exon 1

34. Huntingtin structure is orchestrated by HAP40 and shows a polyglutamine expansion-specific interaction with exon 1

35. Aortic smooth muscle and endothelial plasma membrane [Ca.sup.2+] pump isoforms are inhibited differently by the extracellular inhibitor caloxin 1b1

36. Design, Synthesis, and Evaluation of WD-Repeat-Containing Protein 5 (WDR5) Degraders

37. HAP40 orchestrates huntingtin structure for differential interaction with polyglutamine expanded exon 1

38. Pharmacological targeting of a PWWP domain demonstrates cooperative control of NSD2 localization

39. A First-in-Class, Highly Selective and Cell-Active Allosteric Inhibitor of Protein Arginine Methyltransferase 6

40. Discovery of Small-Molecule Antagonists of the PWWP Domain of NSD2

41. A First-in-class, Highly Selective and Cell-active Allosteric Inhibitor of Protein Arginine Methyltransferase 6 (PRMT6)

42. Discovery of Small-Molecule Antagonists of the PWWP Domain of NSD2

43. Discovery of a First-in-Class Protein Arginine Methyltransferase 6 (PRMT6) Covalent Inhibitor

46. Therapeutic Targeting of RNA Splicing Catalysis through Inhibition of Protein Arginine Methylation

47. Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress responses

48. Abstract 1646: Discovery and characterization of BAY-6035, a novel benzodiazepine-based SMYD3 inhibitor

49. LLY-283, a Potent and Selective Inhibitor of Arginine Methyltransferase 5, PRMT5, with Antitumor Activity

50. TP-064, a potent and selective small molecule inhibitor of PRMT4 for multiple myeloma

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