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3. Prevalence and Clinical Correlations of Antibodies Against Six β2-Glycoprotein-I-Related Peptides in the Antiphospholipid Syndrome

Author

Shoenfeld, Y., Krause, I., Kvapil, F., Sulkes, J., Lev, S., Von Landenberg, P., Font, J., Zaech, J., Cervera, R., Piette, J. C., Boffa, M. C., Khamashta, M. A., Bertolaccini, M. L., Hughes, G. R. V., Youinou, P., Meroni, P. L., Pengo, V., Alves, J. D., Tincani, A., Szegedi, G., Lakos, G., Sturfelt, G., Jönsen, A., Koike, T., Sanmarco, M., Ruffatti, A., Ulcova-Gallova, Z., Praprotnik, S., Rozman, B., Lorber, M., Vriezman, V. B., and Blank, M.

Published
2003
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35. Features associated with epilepsy in the antiphospholipid syndrome

Author

Shoenfeld, Y, Lev, S, Blatt, I, Blank, M, Font, J, von Landenberg, P, Lev, N, Zaech, J, Cervera, R, Piette, Jc, Bertolaccini, Ml, Hughes, Gr, Youinou, P, Meroni, Pl, Pengo, V, Alves, Jd, Tincani, Angela, Szegedi, G, Lakos, G, Sturfelt, G, Jonsen, A, Koike, T, Sanmarco, M, Ruffatti, A, Ulcova Gallova, Z, Praprotnik, S, Rozman, B, Lorber, M, Chapman, J, van Breda Vriezman PJ, and Damoiseaux, J.

Published
2004

36. Features associated with epilepsy in the antiphospholipid syndrome

Author

Shoenfeld, Y., Lev, S., Blatt, I., Font, J., VON LANDENBERG, P., Lev, N., Zaech, J., Cervera, R., Piette, J. C., Bertolaccini, M. L., Hughes, G. R., Youinou, P., Meroni, P. L., Pengo, Vittorio, Alves, J. D., Tincani, A., Szegedi, G., Lakos, G., Sturfelt, G., Jonsen, A., Koike, T., Sanmarco, M., Ruffatti, Amelia, ULCOVA GALLOVA, Z., Praprotnik, S., Rozman, B., Lorber, M., Chapman, J., VAN BREDA VRIEZMAN, P. J., and Damoiseaux, J.

Published
2004

38. Prevalence and clinical correlations of antibodies against six beta2-glycoprotein-I-related peptides in the antiphospholipid syndrome

Author

Shoenfeld, Y., Krause, I., Kvapil, F., Sulkes, J., Lev, S., Landenberg, P., Font, J., Zaech, J., Cervera, R., Piette, J. C., Boffa, M. C., Khamashta, M. A., Maria Laura Bertolaccini, Hughes, G. R. V., Youinou, P., Meroni, P. L., Pengo, V., Alves, J. D., Tincani, A., Szegedi, G., Lakos, G., Sturfelt, G., Jönsen, A., Koike, T., Sanmarco, M., Ruffatti, A., Ulcova-Gallova, Z., Praprotnik, S., Rozman, B., Lorber, M., Vriezman, V. B., and Blank, M.

Subjects
Adult, Adolescent, beta 2-Glycoprotein I, Molecular Sequence Data, Humans, Lupus Erythematosus, Systemic, Amino Acid Sequence, Middle Aged, Antiphospholipid Syndrome, Peptides, Antibodies, Glycoproteins
Abstract

Two-hundred ninety five patients with the antiphospholipid syndrome (APS) were studied for the presence of antibodies against six anti-beta2GPI-related peptides Abs. The prevalence of a wide spectrum of clinical and laboratory parameters of APS was evaluated in all patients, and correlated with the presence of each anti-beta2GPI peptide antibody. The rates of the various antipeptides Abs ranged from 18.0 to 63.7%. Altogether, 87.1% of the patients had antibody reactivity against at least one of the six beta2GPI-related peptides. A high degree of simultaneous reactivity against several beta2GPI-peptides was found. Positive and negative correlations were found between several antipeptides Abs and the rates of thrombosis and fetal loss. Our results point to a heterogeneous activity of antiphospholipid Abs in APS patients, directed, often concurrently, against various epitopes of the beta2GPI molecule. Evaluation of APS patients for the presence of specific antipeptides Abs may be of a value in predicting the risk for future thrombotic and obstetrical complication, as well as for specific therapeutic purposes.

Published
2003

39. Prevalence and clinical correlations of antibodies against six beta2-Glycoprotein-I related peptides in the antiphospholipid syndrome

Author

Shoenfeld, Y, Krause, I, Kvapil, F, Sulkes, J, Lev, S, VON LANDENBERG, P, Font, J, Zaech, J, Cervera, R, Piette, Jc, Boffa, Mc, Khamashta, Ma, Bertolaccini, Ml, Hughes, Gr, Youinou, P, Meroni, Pl, Pengo, Vittorio, Alves, Jd, Tincani, A, Szegedi, G, Lakos, G, Sturfelt, G, Jonsen, A, Koike, T, Sanmarco, M, Ruffatti, Amelia, ULCOVA GALLOVA, Z, Praprotnik, S, Rozman, B, Lorber, M, Vriezman, Vb, and Blank, M.

Published
2003

41. Increased concentrations of the circulating angiogenesis inhibitor en dostatin in patients with systemic sclerosis

Author

Semsei, I., Zeher, M., Takács, I., Urbán, L., Szegedi, G., Bachmann, M, Semsei Imre (1954-) (vegyész, gerontológus), Szegedi Gyula (1936-) (belgyógyász, immunológus), Kémiai Intézet -- 724, Belgyógyászati Intézet -- 84, III. sz. Belgyógyászati Klinika -- 5, Szerves Kémiai Tanszék -- 729, Immun-hematológiai részleg -- 95, TTK -- TEK, ÁOK -- OEC, and Debreceni Egyetem

Subjects
idegen nyelvű folyóiratközlemény külföldi lapban
Abstract

BIBFORM034025-újratöltve

Published
2000

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