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Your search keyword '"Szabó, Imre Lőrinc"' showing total 21 results
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21 results on '"Szabó, Imre Lőrinc"'

2. Case report: Targeted treatment strategies for Erdheim-Chester disease

Author

Gulyás, Anita, primary, Pinczés, László Imre, additional, Mátyus, János, additional, Végh, Edit, additional, Bedekovics, Judit, additional, Tóth, Judit, additional, Barna, Sándor, additional, Hunya, Zsolt, additional, Szabó, Imre Lőrinc, additional, Gazdag, Annamária, additional, Illés, Árpád, additional, and Magyari, Ferenc, additional

Published
2024
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4. Combining Biomarkers for the Diagnosis of Metastatic Melanoma

Author

Várvölgyi, Tünde, primary, Janka, Eszter Anna, additional, Szász, István, additional, Koroknai, Viktória, additional, Toka-Farkas, Tünde, additional, Szabó, Imre Lőrinc, additional, Ványai, Beatrix, additional, Szegedi, Andrea, additional, Emri, Gabriella, additional, and Balázs, Margit, additional

Published
2023
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5. Combining Biomarkers for the Diagnosis of Metastatic Melanoma.

Author

Várvölgyi, Tünde, Janka, Eszter Anna, Szász, István, Koroknai, Viktória, Toka-Farkas, Tünde, Szabó, Imre Lőrinc, Ványai, Beatrix, Szegedi, Andrea, Emri, Gabriella, and Balázs, Margit

Subjects
JOINTS (Anatomy), MELANOMA, MELANOMA diagnosis, BLOOD lactate, RECEIVER operating characteristic curves, TUMOR markers
Abstract

The early detection of melanoma relapse can improve patient survival; thus, there is a great need for easily accessible biomarkers that facilitate the diagnosis of metastatic disease. We investigated the diagnostic effect of blood biomarkers such as lactate dehydrogenase (LDH), S100B, and osteopontin in the detection of metastases. Clinical data and peripheral blood samples of 206 melanoma patients were collected (no metastasis, N = 120; metastasis, N = 86). The discriminative power of blood biomarkers, patient demographics, and clinicopathological parameters of primary melanomas were evaluated using univariate and multivariate logistic regression models and receiver operating characteristic (ROC) analysis to determine the area under the curve (AUC). Plasma osteopontin levels showed a significant and independent effect on the probability of metastasis, similar to serum S100B levels. In addition, the location of the primary tumor on the lower extremities and the American Joint Committee on Cancer (AJCC) categories pT2b-3a, pT3b-4a, and pT4b were associated with the diagnosis of metastasis. Importantly, the combination of the three blood biomarkers and primary tumor localization and AJCC pT category yielded excellent discrimination (AUC: training set: 0.803; validation set: 0.822). In conclusion, plasma osteopontin can be classified as a melanoma biomarker; moreover, by combining clinicopathological prognostic variables, the diagnostic effect of blood biomarkers in the detection of metastatic melanoma can be improved. [ABSTRACT FROM AUTHOR]

Published
2024
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8. Cytokine profile of the epidermis is region specific and may determine the characteristics of inflammation

Author

Szabó, Lilla, primary, Dajnoki, Zsolt, additional, Somogyi, Orsolya, additional, Gáspár, Krisztián, additional, Hendrik, Zoltán, additional, Szabó, Imre Lőrinc, additional, Szöllősi, Attila Gábor, additional, Dinya, Tamás, additional, Törőcsik, Dániel, additional, Kapitány, Anikó, additional, and Szegedi, Andrea, additional

Published
2023
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10. Chronic Inflammatory Intestinal Disorders in Hidradenitis Suppurativa

Author

Réka, Palatka, primary, Janka, Eszter Anna, additional, Soltész, Lilla, additional, Szabó, Imre Lőrinc, additional, Kapitány, Anikó, additional, Dajnoki, Zsolt, additional, Emri, Gabriella, additional, Nagy, Gábor, additional, Palatka, Károly, additional, Zouboulis, Christos C., additional, Szegedi, Andrea, additional, and Gáspár, Krisztián, additional

Published
2023
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13. Novel insights into the TRPV3-mediated itch in atopic dermatitis

Author

Larkin, Ciara, primary, Chen, Weiwei, additional, Szabó, Imre Lőrinc, additional, Shan, Chunxu, additional, Dajnoki, Zsolt, additional, Szegedi, Andrea, additional, Buhl, Timo, additional, Fan, Yuanyuan, additional, O'Neill, Sandra, additional, Walls, Dermot, additional, Cheng, Wenke, additional, Xiao, Song, additional, Wang, Jiafu, additional, and Meng, Jianghui, additional

Published
2021
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17. Neuropathic itch

Author

Steinhoff, Martin, primary, Oaklander, Anne Louise, additional, Szabó, Imre Lőrinc, additional, Ständer, Sonja, additional, and Schmelz, Martin, additional

Published
2019
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19. BRAF-mutáció pozitív áttétes melanoma célzott gyógyszeres kezelése

Author

Szabó, Imre Lőrinc, Ócsai, Henrietta, Kiss, Borbála Katalin, Kékedi, Kriszta, Kósa, Péter, Várvölgyi, Tünde, Kun, Edina, Kenyeres, Anna, Szöllősi, Attila Gábor, Remenyik, Éva, and Emri, Gabriella

Subjects
Orvostudományok, Klinikai orvostudományok
Abstract

LB

Published
2017

20. Comparison of Immune and Barrier Characteristics in Scalp and Skin Psoriasis.

Author

GÁSPÁR, Krisztián, JENEI, Adrienn, KHASAWNEH, Ahmad, MEDGYESI, Barbara, DAJNOKI, Zsolt, JANKA, Eszter Anna, SZABÓ, Imre Lőrinc, HENDRIK, Zoltán, MÉHES, Gábor, SZEGEDI, Andrea, and KAPITÁNY, Anikó

Subjects
PSORIASIS, SCALP, ROSACEA, SKIN, HIDRADENITIS suppurativa, T helper cells, PSORIATIC arthritis
Abstract

The article explores the comparison of Immune and Barrier Characteristics in Scalp and Skin Psoriasis. It mentions the studies have found different microbiota and chemical milieus in different healthy skin areas. It discusses how healthy skin influences the immune characteristics and consequently, the treatment of psoriasis on distinct skin regions.

Published
2020
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