10 results on '"Syrnioti G"'
Search Results
2. Disaggregating the Asian-American Breast Cancer Population: Disparities in Reconstruction Rates.
- Author
-
Eden CM, Kim L, Jao L, Syrnioti G, Johnson J, Liu A, Zhou XK, Siegel B, Newman LA, Malik M, and Ju T
- Subjects
- Adult, Aged, Female, Humans, Middle Aged, Retrospective Studies, East Asian People, Southeast Asian People, South Asian People, Hispanic or Latino, Black or African American, Asian ethnology, Asian statistics & numerical data, Breast Neoplasms surgery, Breast Neoplasms ethnology, Healthcare Disparities statistics & numerical data, Healthcare Disparities ethnology, Mammaplasty statistics & numerical data, Mastectomy statistics & numerical data
- Abstract
Introduction: Breast cancer (BC) incidence has been increasing among Asian-Americans (AsAms); recent data suggest these patients are less likely to undergo postmastectomy breast reconstruction (PMBR) compared to non-Asian women. Historically, AsAm BC patients are reported in aggregate, masking heterogeneity within this population. We aim to identify patterns of postmastectomy reconstruction among disaggregated AsAm BC patients at our institution., Methods: A retrospective chart review was performed for BC patients who underwent mastectomy between 2017 and 2021. Patient demographic and clinical information was collected including self-reported race/ethnicity and reconstruction at time of mastectomy. Self-identified Asian patients were disaggregated into East Asian, Southeast Asian, South Asian, and 'Asian Other.' We examined rates of reconstruction between the different races and the disaggregated Asian subgroups. Univariable and multivariable analysis was performed to examine patient factors associated with PMBR., Results: Six hundred and five patients met inclusion criteria. Forty seven percent of patients identified as Asian, 36% of which as East Asian. Forty four percent of all patients underwent PMBR. Southeast Asian and South Asian women were least likely to undergo reconstruction, while Hispanic and non-Hispanic Black women were most likely to pursue PMBR (P = 0.020). On multivariable analysis, Hispanic, non-Hispanic White, and non-Hispanic Black women were more likely to undergo reconstruction compared to Asian women. Other factors associated with reconstruction were coverage with private insurance and diagnosis of noninvasive disease., Conclusions: Rates of PMBR are lower among AsAms than non-Asian patients and vary between Asian ethnic subgroups. Further investigation is needed to identify patterns of reconstruction among the disaggregated AsAm population to address disparities., (Copyright © 2024 Elsevier Inc. All rights reserved.)
- Published
- 2024
- Full Text
- View/download PDF
3. Incidental Findings in Trauma Patients: How Big is the Challenge?
- Author
-
Syrnioti G, Hinduja P, Radhakrishna A, Martinez AV, Aggarwal A, Gargiulo NJ, Kothuru RK, and Eisdorfer J
- Subjects
- Humans, Retrospective Studies, Patient Discharge, Documentation, Incidental Findings, Tomography, X-Ray Computed methods
- Abstract
Introduction: The purpose of this study was to examine the prevalence of incidental findings (IFs) identified during workup of trauma patients and the effectiveness with which they were documented and communicated., Materials and Methods: We performed a retrospective analysis of all trauma patients ≥15 y of age in 2018, who underwent at least one computed tomography scan. Patients' Electronic Medical Record was reviewed for the presence of IFs. IFs were classified in three categories: category 1, which includes highly significant findings requiring attention during hospitalization; category 2, which warrants attention in an outpatient basis; and category 3, which includes nonsignificant findings that require no follow-up., Results: 836 patients were identified, of which 582 had at least one IF. Of the patients with IFs; 14 (2.4%) were category 1, 138 (23.7%) were category 2, and 569 (97.8%) met category 3 criteria. All category 1 patients received appropriate documentation of their IFs. Of patients with category 2 findings, only 13% had documentation of the IFs. Patients with IFs had longer length of stay (P: 0.04) and lower probability of being discharged to home (P < 0.01) compared to patients with no IFs. Only 12.5% of the patients admitted to trauma surgery service received an outpatient follow-up., Conclusions: There was timely documentation and intervention for all patients with category 1 IFs. However, 87% of patients with category 2 IFs had inadequate documentation of the IF and outpatient follow-up. Outpatient follow-up of IFs poses a challenge for trauma patients partially due to their discharge disposition., (Copyright © 2023 Elsevier Inc. All rights reserved.)
- Published
- 2024
- Full Text
- View/download PDF
4. Breast Cancer Incidence Among Asian American Women in New York City: Disparities in Screening and Presentation.
- Author
-
Eden CM, Syrnioti G, Johnson J, Fasano G, Bayard S, Alston C, Liu A, Zhou XK, Ju T, Newman LA, and Malik M
- Subjects
- Humans, Female, Asian, New York City, Incidence, Early Detection of Cancer, Breast Neoplasms diagnosis
- Abstract
Background: Asian American (AsAm) women have some of the lowest rates of up-to-date breast cancer screening, and lack of disaggregated racial/ethnic data can mask disparities. We evaluated presentation patterns among AsAms at two hospitals with distinct communities: New York Presbyterian-Queens (NYPQ), in Flushing, Queens and Weill Cornell Medical Center (WCM), on the Upper East Side (UES) neighborhood of Manhattan., Patients and Methods: Patients with newly diagnosed breast cancer between January 2019 and December 2022 were identified using a prospective database and clinical data collected. Patients were categorized as self-reported Asian versus Non-Asian. The Asian group was disaggregated as Chinese-Asian versus Other-Asian. Physician workforce data were obtained from public records., Results: A total of 3546 patients (1162 NYPQ, 2384 WCM) were included. More NYPQ patients identified as Asian compared with WCM (49 vs. 14%, p < 0.001). Asian patients were mostly East Asian Chinese (NYPQ 61%, WCM 53%). More Chinese patients at NYPQ reported Chinese as their preferred language (81 vs. 33%, p < 0.001). Greatest differences of screen-detected disease frequency were seen between NYPQ and WCM Chinese patients (75 vs. 59%, p < 0.001). Eighty percent of NYPQ Chinese patients presented with stage 0/I disease versus 69% at WCM (p = 0.007), a difference not observed between Other-Asian patients (75% NYPQ, 68% WCM, p = 0.095). 3% of UES physicians versus 16% in Flushing reported speaking Chinese., Conclusions: Chinese patients residing in a neighborhood with more Chinese-speaking physicians more frequently presented with screen-detected, early-stage breast cancer. Stage distribution differences were not apparent among the aggregated pool of Other-Asian patients, suggesting cancer disparities may be masked when ethnic groups are studied in aggregate., (© 2023. Society of Surgical Oncology.)
- Published
- 2024
- Full Text
- View/download PDF
5. Social Determinants of Cancer Disparities.
- Author
-
Syrnioti G, Eden CM, Johnson JA, Alston C, Syrnioti A, and Newman LA
- Subjects
- Humans, Social Determinants of Health, Morbidity, World Health Organization, Quality of Life, Neoplasms
- Abstract
Cancer is a major public health issue that is associated with significant morbidity and mortality across the globe. At its root, cancer represents a genetic aberration, but socioeconomic, environmental, and geographic factors contribute to different cancer outcomes for selected population subsets. The disparities in the delivery of healthcare affect all aspects of cancer management from early prevention to end-of-life care. In an effort to address the inequality in the delivery of healthcare among socioeconomically disadvantaged populations, the World Health Organization defined social determinants of health (SDOH) as conditions in which people are born, live, work, and age. These factors play a significant role in the disproportionate cancer burden among different population groups. SDOH are associated with disparities in risk factor burden, screening modalities, diagnostic testing, treatment options, and quality of life of patients with cancer. The purpose of this article is to describe a more holistic and integrated approach to patients with cancer and address the disparities that are derived from their socioeconomic background., (© 2023. Society of Surgical Oncology.)
- Published
- 2023
- Full Text
- View/download PDF
6. Landmark Series: The Cancer Genome Atlas and the Study of Breast Cancer Disparities.
- Author
-
Johnson JA, Moore BJ, Syrnioti G, Eden CM, Wright D, and Newman LA
- Subjects
- Female, Humans, Asian genetics, Disease-Free Survival, Genomics, Tumor Microenvironment genetics, Black or African American genetics, White genetics, United States, Hispanic or Latino genetics, Breast Neoplasms ethnology, Breast Neoplasms genetics, DNA, Neoplasm genetics, Health Status Disparities
- Abstract
Race-related variation in breast cancer incidence and mortality are well-documented in the United States. The effect of genetic ancestry on disparities in tumor genomics, risk factors, treatment, and outcomes of breast cancer is less understood. The Cancer Genome Atlas (TCGA) is a publicly available resource that has allowed for the recent emergence of genome analysis research seeking to characterize tumor DNA and protein expression by ancestry as well as the social construction of race and ethnicity. Results from TCGA based studies support previous clinical evidence that demonstrates that American women with African ancestry are more likely to be afflicted with breast cancers featuring aggressive biology and poorer outcomes compared with women with other backgrounds. Data from TCGA based studies suggest that Asian women have tumors with favorable immune microenvironments and may experience better disease-free survival compared with white Americans. TCGA contains limited data on Hispanic/Latinx patients due to small sample size. Overall, TCGA provides important opportunities to define the molecular, biologic, and germline genetic factors that contribute to breast cancer disparities., (© 2023. Society of Surgical Oncology.)
- Published
- 2023
- Full Text
- View/download PDF
7. Chyloperitoneum After Penetrating Abdominal Trauma: A Report of a Rare Case.
- Author
-
Syrnioti G, Al Awwa G, and Eisdorfer J
- Abstract
The term chyloperitoneum refers to the accumulation of triglyceride-rich fluid in the peritoneal cavity. It is an uncommon clinical condition that usually occurs due to disruption of lymphatic flow secondary to trauma or obstruction. Common causes include penetrating or blunt trauma, iatrogenic injuries, congenital anomalies, malignant neoplasms, infections such as tuberculosis and filariasis, liver cirrhosis, constrictive pericarditis, congestive heart failure, inflammatory conditions, such as sarcoidosis and pancreatitis, and radiation- and drug-related pathologies. We present a case of chyloperitoneum in a 33-year-old woman secondary to penetrating abdominal trauma secondary to a gunshot wound. The patient was successfully managed with total parenteral nutrition and octreotide administration. To our knowledge, this is the only case of chylous ascites caused by a penetrating injury that has been reported in the literature. Conservative management with the initiation of total parenteral nutrition and octreotide led to the resolution of this condition., Competing Interests: The authors have declared that no competing interests exist., (Copyright © 2023, Syrnioti et al.)
- Published
- 2023
- Full Text
- View/download PDF
8. The Landmark Series: The Breast Cancer Burden of the Asian American Population and the Need for Disaggregated Data.
- Author
-
Eden CM, Johnson J, Syrnioti G, Malik M, and Ju T
- Subjects
- Humans, United States epidemiology, Female, Asian, Ethnicity, Early Detection of Cancer, Breast Neoplasms prevention & control
- Abstract
The Asian American Pacific Islander (AAPI) population is a heterogeneous group of people from geographically and ethnically distinct regions of the world. Traditionally, these patients have been reported as one large aggregate in the breast cancer literature under the race category of "Asian." A detailed examination of this group shows compelling evidence that breast cancer manifests differently among Asian ethnic subgroups, resulting in overlooked health disparities when these races are grouped together. The AAPI community is the fastest growing ethnic group in the United States, and their incidence of breast cancer is increasing at rates greater than among their non-Asian counterparts. When these patients are disaggregated by race, they show wide variations in breast cancer screening, presentation, treatment, and outcomes. This population often faces additional unique challenges in the health care system due to cultural, social, health literacy, and language barriers, which can contribute to further disparity. Our landmark series aims to showcase the breadth of the breast cancer burden in the AAPI population and highlight the need for disaggregated ethnic data., (© 2023. Society of Surgical Oncology.)
- Published
- 2023
- Full Text
- View/download PDF
9. Myoepithelial Carcinoma Ex Pleomorphic Adenoma of the Submandibular Gland: A Case Report.
- Author
-
Syrnioti G, Syrnioti A, Abdullah A, Lui X, and Mendoza E
- Abstract
Carcinoma ex pleomorphic adenoma (Ca-ex-PA) is a rare tumor that arises from the malignant transformation of a primary or recurrent pleomorphic adenoma. Despite being benign, pleomorphic adenomas can rarely undergo malignant transformation. Risk factors include a long-standing primary tumor, a prior history of radiation exposure, increased tumor size, and recurrent disease. Ca-ex-PA usually affects patients between the sixth and eighth decades of life, approximately 10 to 20 years after the development of a pleomorphic adenoma. Patients usually present with the rapid expansion of an already existing mass. We describe a case report of a patient who presented with Ca-ex-PA of the submandibular gland. The patient underwent surgical excision of the affected gland, which was consistent with a widely invasive myoepithelial Ca-ex-PA. The patient underwent postoperative radiation to the neck and the tumor bed. No local or distant recurrence was noted during the one-year follow-up. Due to the rarity of the disease entity and the infrequent location of the tumor, this case presents a particular diagnostic and therapeutic challenge., Competing Interests: The authors have declared that no competing interests exist., (Copyright © 2023, Syrnioti et al.)
- Published
- 2023
- Full Text
- View/download PDF
10. Nail Reconstruction With Nail Bed Graft From Big Toe: A Case Report.
- Author
-
Syrnioti G, Ayyat M, Jean C, Ahmad H, and Ahmad N
- Abstract
Fingertip injuries with loss of the nail bed can lead to permanent deformities or absent nail formation. This is a case report of a 17-year-old female who sustained a blunt injury to the left second index finger with nail avulsion. The patient underwent nail reconstruction with a split-thickness graft from the sterile matrix of the left great toe. Postoperatively both the donor and the recipient sites appear to be healing appropriately. Since nail reconstruction with toe graft is rarely performed, this case is of particular interest due to its excellent postoperative outcomes., Competing Interests: The authors have declared that no competing interests exist., (Copyright © 2022, Syrnioti et al.)
- Published
- 2022
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.