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2. Prévalence de la co-infection Streptococcus pneumoniae et VIH chez les enfants de 0 à 35 à Bamako au Mali

Author

SANGARE SA, MAIGA AI, DIALLO S, GORO M, SYLLA MB, and SYLLA M

Subjects
Streptococcus pneumoniae, VIH, dépistage, co-infection, Bamako, Mali, Medicine, Microbiology, QR1-502
Abstract

But du travail : Le but de notre étude était de déterminer la prévalence de la co-infection Streptococcus pneumoniae et VIH chez les enfants de 0 à 35 mois à Bamako au Mali. Matériel et Méthodes : Nous avons recruté 173 enfants chez lesquels on a effectué l’hémoculture et le test VIH. Les échantillons pour l’hémoculture ont été collectés chez tous les enfants d’une façon stérile et inoculés dans des flacons d'hémoculture, puis transportés au laboratoire et placés dans une machine de culture automatisée appelée Bactec 9050. Tous les échantillons de sérum/plasma ont été d’abord soumis à un test simple/rapide de sensibilité élevée : soit DETERMINE, la confirmation et le typage par l’IMMUNOCOMB II pour le VIH-1 et VIH-2. Résultats : Sur 173 enfants, 78 (45,10%) sont âgés de 12 à 23 mois, 101 (58,40%) sont de sexe masculin, 39 cas (22,54%) ont une infection à Streptococcus pneumoniae avec 134 témoins (77,46%) sans infection diagnostiquée. Ainsi nous avons dépisté 9 cas de positivité au VIH soit 5,20%. Parmi les 9 enfants seuls 2 avaient une co-infection Streptococcus pneumoniae et VIH. Conclusion : La co-infection Streptococcus pneumoniae et VIH est faible dans notre étude et une autre étude de plus grande taille mérite d’être réalisée pour confirmer nos résultats.

Published
2014

3. Kalman filter model, as a tool for short-term forecasting of solar potential: case of the Dakar site

Author

Mbaye A., Ndong J., NDiaye M.L., Sylla M., Aidara M.C., Diaw M., NDiaye M.F., Ndiaye Papa Alioune, and Ndiaye A.

Subjects
Kalman filter, solar potential, Prediction, Dakar, short-term, Environmental sciences, GE1-350
Abstract

The prediction of solar potential is an important step toward the evaluation of PV plant production for the best energy planning. In this study, the discrete Kalman filter model was implemented for short-term solar resource forecasting one the Dakar site in Senegal. The model input parameters are constituted at a time t of the air temperature, the relative humidity and the global solar radiation. The expected output at time t+T is the global solar radiation. The model performance is evaluated with the square root of the normalized mean squared error (NRMSE), the absolute mean of the normalized error (NMAE), the average bias error (NMBE). The model Validation is carried out by means of the data measured within the Polytechnic Higher School of Dakar for one year. The simulation results following the 20 minute horizon show a good correlation between the prediction and the measurement with an NRMSE of 4.8%, an NMAE of 0.27% and an NMBE of 0.04%. This model could contribute to help photovoltaic based energy providers to better plan the production of solar photovoltaic plants in Sahelian environments.

Published
2018
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4. Variabilité selon le captureur de l'efficacité de répulsifs à base d'huiles végétales dans la protection individuelle contre les piqûres de Simulium damnosum s. l.

Author

Sylla M., Konan L., Doannio J.M.C., and Traoré S.

Subjects
Simulium damnosum s. l., nuisance, répulsifs, attractivité individuelle, Infectious and parasitic diseases, RC109-216
Abstract

Dans le présent article, nous faisons état de la variabilité selon le captureur de l'efficacité de répulsifs à base d'huiles végétales appliquées sur la peau contre les piqûres de Simulium damnosum s. l. Les expérimentations ont été effectuées en zones de savane (Chaussée-Niaka) et de forêt (Soubré) de Côte d'Ivoire. Les formulations (lotions, crèmes] testées lors de ces travaux ont été obtenues à partir d'huiles d'amande de palme (Elaeis guineensis), de coco (Cocos nucifera) et de gobi (Carapa procera). La technique classique de capture sur homme à l'aide de tubes à hémolyse en matière plastique a été utilisée. Pour chaque journée d'expérimentation, un captureur non traité (jambes non enduites de répulsif) servait de témoin. Les résultats indiquent qu'en savane, quels que soient le répulsif et le captureur, la densité simulidienne se situait de 1 à 4, 1 à 6 et de 2 à 10 simulies par homme et par jour lorsque le captureur était respectivement protégé avec le coco, le palmiste et le gobi. Avec les mêmes répulsifs, en zone de forêt, l'agressivité simulidienne variait de 9 à 16, de 2 à 30 et de 8 à 49 piqûres par jour. En comparaison, le témoin recevait de 67 à 90 et de 310 à 533 piqûres par jour, respectivement en zones de savane et de forêt. Malgré les variations importantes dans le nombre de simulies capturées en fonction du captureur choisi, nos résultats montrent que quels que soient le répulsif et l'espèce simulidienne, une protection similaire est conférée à tous les captureurs. Ils indiquent également que le recours à des substances naturelles locales, utilisées comme répulsifs en application dermique, est l'une des meilleures méthodes de protection personnelle contre les simulies.

Published
2002
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10. Adams-Oliver Syndrome: About A Case

Author

Sylla, F., primary, Keita, Dr. Lassine, additional, Ba, K., additional, Keita, C., additional, Traore, C., additional, Kanté, M., additional, Koné, N., additional, Fofana, Y., additional, Dicko, A. G., additional, Diakité, M., additional, Kontao, N., additional, Dicko, F., additional, and Sylla, M., additional

Published
2023
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11. Assembling a global database of child pneumonia studies to inform WHO pneumonia management algorithm:Methodology and applications

Author

Martin, H., Falconer, J., Addo-Yobo, E., Aneja, S., Arroyo, L. M., Asghar, R., Awasthi, S., Banajeh, S., Bari, A., Basnet, S., Bavdekar, A., Bhandari, N., Bhatnagar, S., Bhutta, Z. A., Brooks, A., Chadha, M., Chisaka, N., Chou, M., Clara, A. W., Colbourn, T., Cutland, C., D'Acremont, V., Echavarria, M., Gentile, A., Gessner, B., Gregory, C. J., Hazir, T., Hibberd, P. L., Hirve, S., Hooli, S., Iqbal, I., Jeena, P., Kartasasmita, C. B., King, C., Libster, R., Lodha, R., Lozano, J. M., Lucero, M., Lufesi, N., MacLeod, W. B., Madhi, S. A., Mathew, J. L., Maulen-Radovan, I., McCollum, E. D., Mino, G., Mwansambo, C., Neuman, M. I., Nguyen, N. T. V., Nunes, M. C., Nymadawa, P., O'Grady, K. F., Pape, J. W., Paranhos-Baccala, G., Patel, A., Picot, V. S., Rakoto-Andrianarivelo, M., Rasmussen, Z., Rouzier, V., Russomando, G., Ruvinsky, R. O., Sadruddin, S., Saha, S. K., Santosham, M., Singhi, S., Soofi, S., Strand, T. A., Sylla, M., Thamthitiwat, S., Thea, D. M., Turner, C., Vanhems, P., Wadhwa, N., Wang, J., Zaman, S. M., Campbell, H., Nair, H., Qazi, S. A., Nisar, Y. B., and World Health Organization Pneumonia Research Partnership to Asse

Subjects
Male, Health Policy, Research, Public Health, Environmental and Occupational Health, Infant, Newborn, Infant, Pneumonia, World Health Organization, Pneumonia/drug therapy, Child, Preschool, Humans, Female, Child, Case Management, Algorithms
Abstract

BACKGROUND: The existing World Health Organization (WHO) pneumonia case management guidelines rely on clinical symptoms and signs for identifying, classifying, and treating pneumonia in children up to 5 years old. We aimed to collate an individual patient-level data set from large, high-quality pre-existing studies on pneumonia in children to identify a set of signs and symptoms with greater validity in the diagnosis, prognosis, and possible treatment of childhood pneumonia for the improvement of current pneumonia case management guidelines.METHODS: Using data from a published systematic review and expert knowledge, we identified studies meeting our eligibility criteria and invited investigators to share individual-level patient data. We collected data on demographic information, general medical history, and current illness episode, including history, clinical presentation, chest radiograph findings when available, treatment, and outcome. Data were gathered separately from hospital-based and community-based cases. We performed a narrative synthesis to describe the final data set.RESULTS: Forty-one separate data sets were included in the Pneumonia Research Partnership to Assess WHO Recommendations (PREPARE) database, 26 of which were hospital-based and 15 were community-based. The PREPARE database includes 285 839 children with pneumonia (244 323 in the hospital and 41 516 in the community), with detailed descriptions of clinical presentation, clinical progression, and outcome. Of 9185 pneumonia-related deaths, 6836 (74%) occurred in children CONCLUSIONS: This data set could identify an improved specific, sensitive set of criteria for diagnosing clinical pneumonia and help identify sick children in need of referral to a higher level of care or a change of therapy. Field studies could be designed based on insights from PREPARE analyses to validate a potential revised pneumonia algorithm. The PREPARE methodology can also act as a model for disease database assembly.

Published
2022

12. Epidemiology and Management of 144 Eclampsia Patients at Sikasso Hospital

Author

Traoré S. A., Sylla M., Cissouma A, Coulibaly B., Coulibaly M., Cissé A, Touré O, Kanté M., Traoré S., Diassana M, Traoré B., Traoré Y., Diallo A, and Diassana M.

Subjects
General Medicine
Abstract

Plummer Vinson syndrome is a rare condition characterized by cervical dysphagia associated with iron deficiency anemia and a ring on the upper esophagus. Sometimes its unusual presentation can lead to misdiagnosis. We report the observation of a patient with Plummer-Vinson syndrome, revealed by upper dysphagia.

Published
2021

13. Diagnosis of paediatric TB using Xpert® MTB/RIF Ultra on fresh respiratory samples

Author

Sabi, I, Olomi, W, Nkereuwem, E, Togun, T, Gomez, MP, Sylla, M, Diarra, B, Sanogo, M, Sichone, E, Mahiga, H, Njeleka, F, Ebonyi, AO, Egere, U, Ntinginya, NE, Hoelscher, M, Heinrich, N, and Kampmann, B

Abstract

OBJECTIVE: To evaluate the diagnostic accuracy of Xpert® MTB/RIF Ultra (Ultra) on fresh respiratory samples for the diagnosis of pulmonary TB (PTB) in children.METHODS: Between July 2017 and December 2019, children with presumed TB were prospectively enrolled at clinical sites in three African countries. Children were assessed using history, physical examination and chest X-ray. Sputum or gastric aspirate samples were analysed using Ultra and culture. The diagnostic accuracy of Ultra was calculated against culture as the reference standard.RESULTS: In total, 547children were included. The median age was 4.7 years, 77 (14.1%) were HIV infected and 77 (14.1%) had bacteriologically confirmed TB. Ultra detected an additional 20 cases in the group of children with negative culture results. The sensitivity of Ultra was 66.3% (95% CI 47-82), and the specificity was 95.4% (95% CI 89-99) when assessed against culture as the reference standard.CONCLUSION: Despite the improved performance of Ultra as compared to Xpert as was previously reported, its sensitivity remains sub-optimal for the detection of TB in children. Ultra detected additional 20 cases which otherwise could not have been detected by culture alone, suggesting that the latter is an imperfect reference standard.

Published
2022

14. Iatrogenic Urological Lesions Secondary to Gyneco-Obstetric Surgery

Author

Traoré S., Traoré S. A., Sylla M., Dembélé O., Coulibaly M., Cissouma A., Cissé A., Touré O., Kanté M., Diassana M., Traoré B., Traoré Y., and Diallo A.

Subjects
General Engineering
Abstract

Introduction: The aim of this study was to analyze the epidemioclinical aspects of iatrogenic urological lesions, to describe the anatomical lesions and to establish a link between surgery and these lesions. Materials and methods: Descriptive and retrospective study carried out in the urology department of Sikasso hospital from January 2016 to December 2018. Results: In total, 26 patients suffering from iatrogenic urological lesions secondary to gyneco-obstetric surgery were recruited, ie 2.86% of our activities and 17.74% of female urogenital lesions. Average age: 31, 88 ± 11, 54 years old; Average age at 1st marriage: 15.00 ± 1.87 (12 - 20). Almost all of our patient was out of school, homemaker, in unpaid jobs and 83.33% from rural Sikasso. Seventeen patients (65, 38%) were 1.55 m shorter and of these 25% had not received antennal care. Labor stagnation (mean duration: 47, 22 ± 20, 48 hours) was the main indication with 90.47% of stillbirths. The main complaint (92, 30%) of our patients was leakage of urine, followed by abdominal-lumbar pain and abdominal distension associated with anuria. Urogenital fistulas (91.66%); urinary tract infection (20.83%) and acute renal failure 11.53% were common complications. The most common causal operation (76.91%) was cesarean section, often performed by general practitioners. The bladder was more frequently (65, 40%) affected by these injuries than the ureter (34, 60%). Regarding the surgical approach, an open transvesical fistulorrhaphy in two planes or a vesicoureteric reimplantation was performed. The result was excellent in 88, 46% of cases and bad in 11 and 53%. Conclusions: Iatrogenic urologic complications of gyneco-obstetric surgery were not uncommon. Early diagnosis and appropriate management could improve its prognosis. The preventive measures are based on the promotion of girls' education and socio-economic life, good antennal care and the continuing training of health care providers in charge of managing obstetric

Published
2021

15. Clinical, Therapeutic and Epidemiology Aspects of Uterine Rupture in the Gyneco-Obstetrics Departement of the Sikasso Hospital

Author

Traoré S. A., Sylla M., Sanogo A D., Coulibaly M., Cissouma A, Touré O., Guindo A., Kanté M., Traoré S., Diassana M., Traoré B., Traoré Y., Diallo A., and Diallo A

Subjects
General Medicine
Abstract

Introduction: Uterine rupture is one of the main causes of maternal and fetal mortality in Mali. Method: This was a descriptive cross-sectional prospective study in the Gynecology - Obstetrics department of the Sikasso hospital from January 01, 2018 to June 30, 2019, i.e. eighteen months. The study covered all cases of childbirth recorded in the Gynecology - Obstetrics Department of Sikasso Hospital during the study period. Results: During these 18 months of study, we recorded 68 cases of uterine rupture out of a total of 4,815 deliveries, ie a frequency of 1.41%. Regarding the mode of admission, 93% were evacuated against 7% who came on their own. For the evacuated patients, 82.4% arrived by ambulance against 13.2% by personal car and 4.4% by public transport. The duration of labor was ≥ 12 hours in 22.1% of cases. Lesions were associated with rupture in 19.1% of cases. The use of uterotonics was responsible for uterine rupture in 54.4% of cases and 7.4% of patients had a generally narrowed pelvis. Simple hysterorrhaphy was performed in 30%, hysterorrhaphy associated with tubal ligation resection in 50% and subtotal hysterectomy in 20% of cases. Lack of schooling, the lack and poor quality of prenatal care have been factors that increase maternal and perinatal morbidity and mortality. The maternal-fetal prognosis was poor with 11.7% maternal deaths and 86.8% perinatal deaths. Conclusion: Better screening of populations at risk, quality ANC, early diagnosis and rapid and adequate management will improve the maternal-fetal prognosis.

Published
2021

16. Epidemiological Profile of Premature Newborns Monitored at the Kangaroo Unit at Sikasso Hospital

Author

Cissouma A, Traoré S. A, Kassogue D, Maiga H, Sylla M, Poma H, Kelema P, Diallo F, Traoré I, Dicko-Traoré F, Diall H, Sacko K, Traoré M, Touré M S, and Coulibaly MB

Subjects
General Medicine
Abstract

The objective of this study was to determine the epidemiological profile of preterm infants followed at the Kangaroo Unit. Patients and Methods: This was a descriptive cross-sectional study carried out in the Pediatrics Department of Sikasso hospital (Mali), a second-reference hospital from 1 January 2019 to 31 December 2019 on a comprehensive sample of all preterm infants followed at the unit during the study period. Results: We collected 94 files out of 194, a frequency of 48.4%. The average age of mothers was 28.5 years and 92, 5% were married, the out-of-school represented 51%. Housewives were the majority with 78.8% and living in urban communities in 70.2%. Primigest accounted for 37.2% of cases; 62.7% of women had completed at least four antenatal consultations. Malaria was found in 38.2% of pathologies during pregnancy. In 73.4% of the cases the newborns were born from a vaginal birth and 54.2% from birth in the born. The sex ratio is 1.5 and average gestational age is 31 SA. The average weight was 1325g. 40% of newborns were successfully followed up to 12 months of corrected age, sight loss was 21.2% and 40.4% were outstanding follow-up, we recorded 7 deaths or 7.4%. From 3 months to 12 months of corrected age all infants had an average weight located within WHO standard standards. Conclusion: The management of premature babies remains a major challenge for the pediatric services of our hospitals.

Published
2021

19. The Climatic Impact-Driver Framework for Assessment of Risk-Relevant Climate Information

Author

Ruane, A. C. Vautard, R. Ranasinghe, R. Sillmann, J. Coppola, E. Arnell, N. Cruz, F. A. Dessai, S. Iles, C. E. Islam, A. K. M. S. Jones, R. G. Rahimi, M. Carrascal, D. R. Seneviratne, S. I. Servonnat, J. Sörensson, A. A. Sylla, M. B. Tebaldi, C. Wang, W. Zaaboul, R. and Ruane, A. C. Vautard, R. Ranasinghe, R. Sillmann, J. Coppola, E. Arnell, N. Cruz, F. A. Dessai, S. Iles, C. E. Islam, A. K. M. S. Jones, R. G. Rahimi, M. Carrascal, D. R. Seneviratne, S. I. Servonnat, J. Sörensson, A. A. Sylla, M. B. Tebaldi, C. Wang, W. Zaaboul, R.

Abstract

The climate science and applications communities need a broad and demand-driven concept to assess physical climate conditions that are relevant for impacts on human and natural systems. Here, we augment the description of the “climatic impact-driver” (CID) approach adopted in the Working Group I (WGI) contribution to the Intergovernmental Panel on Climate Change (IPCC) Sixth Assessment Report. CIDs are broadly defined as “physical climate system conditions (e.g., means, events, and extremes) that affect an element of society or ecosystems. Depending on system tolerance, CIDs and their changes can be detrimental, beneficial, neutral, or a mixture of each across interacting system elements and regions.” We give background information on the IPCC Report process that led to the development of the 7 CID types (heat and cold, wet and dry, wind, snow and ice, coastal, open ocean, and other) and 33 distinct CID categories, each of which may be evaluated using a variety of CID indices. This inventory of CIDs was co-developed with WGII to provide a useful collaboration point between physical climate scientists and impacts/risk experts to assess the specific climatic phenomena driving sectoral responses and identify relevant CID indices within each sector. The CID Framework ensures that a comprehensive set of climatic conditions informs adaptation planning and risk management and may also help prioritize improvements in modeling sectoral dynamics that depend on climatic conditions. CIDs contribute to climate services by increasing coherence and neutrality when identifying and communicating relevant findings from physical climate research to risk assessment and planning activities.

Published
2022
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20. CONNAISSANCES ET PRATIQUES DE LA PRESCRIPTION DU FER PAR LE PERSONNEL DU SERVICE DE PEDIATRIE DU CHU GABRIEL TOURE DE BAMAKO.

Author

Diakité, A. A., Dicko-Traoré, F., Sylla, M., Touré, A., Diall, H., Maiga, B., Traoré, F., Dembele, G., Togo, B., and Sidibé, T.

Abstract

Copyright of Mali Médical is the property of Mali Medical, Faculte de Medecine, de Pharmacie et d'Odonto-stomatologie and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2023

22. RegCM4 : model description and preliminary tests over multiple CORDEX domains

Author

Giorgi, F., Coppola, E., Solmon, F., Mariotti, L., Sylla, M. B., Bi, X., Elguindi, N., Diro, G. T., Nair, V., Giuliani, G., Turuncoglu, U. U., Cozzini, S., Güttler, I., O'Brien, T. A., Tawfik, A. B., Shalaby, A., Zakey, A. S., Steiner, A. L., Stordal, F., Sloan, L. C., and Brankovic, C.

Published
2012

23. Isoniazid preventive therapy in child household contacts of adults with active TB in Bamako, Mali

Author

Tolofoudie, M., primary, Somboro, A., additional, Diarra, B., additional, Sarro, Y. S., additional, Drame, H. B., additional, Togo, A. C. G., additional, Sanogo, M., additional, Dembele, A., additional, Togun, T., additional, Nkereuwem, E., additional, Baya, B., additional, Konate, B., additional, Egere, U., additional, Traore, M., additional, Maiga, M., additional, Saliba-Shaw, K., additional, Kampmann, B., additional, Diallo, S., additional, Doumbia, S., additional, and Sylla, M., additional

Published
2021
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29. Global temporal changes in the proportion of children with advanced disease at the start of combination antiretroviral therapy in an era of changing criteria for treatment initiation

Author

Panayidou, K, Davies, M, Anderegg, N, Egger, M, Fatti, G, Vinikoor, M, Sawry, S, Ehmer, J, Eley, B, Phiri, S, Technau, K, Chimbetete, C, Rabie, H, Boulle, A, Tanser, F, Wood, R, Wools-Kaloustian, K, Vreeman, R, Oyaro, P, Ayaya, S, Nakigozi, G, Musick, B, Yiannoutsos, C, Amorissani-Folquet, M, Takassi, E, Sylla, M, Renner, L, Malateste, K, Desmonde, S, Leroy, V, Kurniati, N, Hansudewechakul, R, Nguyen, L, Ly, P, Truong, K, Kariminia, A, Sohn, A, Edmonds, A, Yumo, H, Dusingize, J, Yotebieng, M, Judd, A, Rojo, P, Smit, C, Grabar, S, Warszwarski, J, Chene, G, Raban, D, Patel, K, Seage, G, Van Dyke, R, Oleske, J, Williams, P, Abzug, M, Succi, R, Machado, D, Pinto, J, Rouzier, V, Luque, M, Mejia, F, Khol, V, Tucker, J, Kumarasamy, N, Saghayam, S, Chandrasekaran, E, Wati, D, Vedaswari, D, Malino, I, Muktiarti, D, Fong, S, Lim, M, Daut, F, Nik Yusoff, N, Mohamad, P, Mohamed, T, Drawis, M, Nallusamy, R, Chan, K, Sudjaritruk, T, Sirisanthana, V, Aurpibul, L, Oberdorfer, P, Denjanta, S, Watanaporn, S, Kongphonoi, A, Lumbiganon, P, Kosalaraksa, P, Tharnprisan, P, Udomphanit, T, Jourdain, G, Puthanakit, T, Anugulruengkitt, S, Phadungphon, C, Chokephaibulkit, K, Lapphra, K, Phongsamart, W, Sricharoenchai, S, Du, Q, Nguyen, C, Do, V, Ha, T, An, V, Khu, D, Pham, A, Le, O, Ross, J, Sethaputra, C, Law, M, Cahn, P, Cesar, C, Fink, V, Sued, O, Dell'Isola, E, Perez, H, Valiente, J, Yamamoto, C, Grinsztejn, B, Veloso, V, Luz, P, de Boni, R, Wagner, S, Friedman, R, Moreira, R, Ferreira, F, Maia, M, de Menezes Succi, R, Barbosa Gouv E A, A, Wolff, M, Cortes, C, Rodriguez, M, Allendes, G, Pape, J, Marcelin, A, Perodin, C, Padgett, D, Madero, J, Ramirez, B, Belaunzaran, P, Vega, Y, Gotuzzo, E, Carriquiry, G, Mcgowan, C, Shepherd, B, Sterling, T, Jayathilake, K, Person, A, Rebeiro, P, Giganti, M, Castilho, J, Duda, S, Maruri, F, Vansell, H, P E Lagie, N, Gateretse, P, Munezero, J, Nitereka, V, Niyongabo, T, Twizere, C, Bukuru, H, Nahimana, T, Biziragusenyuka, J, Manyundo, R, Atsu, K, Mbuh, T, Ajeh, R, Benwi, M, Dzudie, A, Mbuh, A, Ngamani, M, Nkome, V, Amadou, D, Ngassam, E, Pefura Yone, E, Ewanoge, A, Fuhngwa, N, Moki, C, Akele, C, Kitetele, F, Lelo, P, Tabala, M, Okitolonda, E, Wenzi, L, Diafouka, M, Ekat, M, Nsonde, D, Mafou, A, Ntarambirwa, F, Tuyishimire, Y, Hakizimana, T, Ayinkamiye, J, Mukantwali, S, Kayitesi, H, Uwamahoro, O, Habumuremyi, V, Mukamana, J, Kubwimana, G, Mugenzi, P, Muhoza, B, Munyaneza, A, Ndahiro, E, Nyiransabimana, D, D'Amour Sinayobye, J, Sugira, V, Benekigeri, C, Mbaraga, G, Adedimeji, A, Anastos, K, Dilorenzo, M, Murchison, L, Addison, D, Baker, M, Brazier, E, Jones, H, Kelvin, E, Kulkarni, S, Nash, D, Tymejczyk, O, Elul, B, Cai, X, Hoover, D, Kim, H, Li, C, Shi, Q, Lancaster, K, Kuniholm, M, Parcesepe, A, Kimmel, A, Mcnairy, M, Diero, L, Plus, A, Bukusi, E, Ssali, J, Nalugoda, F, Somi, G, Lyamuya, R, Ngonyani, K, Lugina, E, Urassa, M, Michael, D, Zannou, M, Poda, A, Sarfo, F, Messou, E, Chenal, H, Minga, K, Bissagnene, E, Tanon, A, Seydi, M, Patassi, A, Koumakpai-Adeothy, S, N'Gbeche, S, Bosse, C, Kouakou, K, Folquet, M, Eboua, F, Traore, F, Dabis, F, Arrive, E, Balestre, E, Becquet, R, Bernard, C, Arikawa, S, Doring, A, Jaquet, A, Rabourdin, E, Tiendrebeogo, T, Jesson, J, Ekouevi, D, Azani, J, Coffi E, P, Gnepa, G, Kouadio, C, Tchounga, B, Maartens, G, Lettow, M, Muhairwe, J, Jores, A, Kamenova, K, Fox, M, Prozesky, H, Zangerle, R, Touloumi, G, Warszawski, J, Meyer, L, Krause, M, Ghosn, J, Leport, C, Wittkop, L, Reiss, P, Wit, F, Prins, M, Bucher, H, Gibb, D, Fatkenheuer, G, Del Amo, J, Obel, N, Thorne, C, Mocroft, A, Kirk, O, Stephan, C, Perez-Hoyos, S, Hamouda, O, Bartmeyer, B, Chkhartishvili, N, Noguera-Julian, A, Antinori, A, D'Arminio Monforte, A, Brockmeyer, N, Prieto, L, Conejo, P, Soriano-Arandes, A, Battegay, M, Kouyos, R, Mussini, C, Tookey, P, Casabona, J, Miro, J, Castagna, A, Konopnick, D, Goetghebuer, T, Sonnerborg, A, Torti, C, Sabin, C, Teira, R, Garrido, M, Haerry, D, de Wit, S, Costagliola, D, Raben, D, Barger, D, Schwimmer, C, Termote, M, Campbell, M, Frederiksen, C, Friis-Moller, N, Kjaer, J, Brandt, R, Berenguer, J, Bohlius, J, Bouteloup, V, Cozzi-Lepri, A, Dorrucci, M, Dunn, D, Furrer, H, Guiguet, M, Lambotte, O, Lodi, S, Matheron, S, Monge, S, Nakagawa, F, Paredes, R, Phillips, A, Puoti, M, Rohner, E, Schomaker, M, Sterne, J, Thiebaut, R, van der Valk, M, Hazra, R, Heckman, B, O'Gara, E, Siminski, S, Panayidou K., Davies M. -A., Anderegg N., Egger M., Fatti G., Vinikoor M., Sawry S., Ehmer J., Eley B., Phiri S., Technau K. -G. u. N., Chimbetete C., Rabie H., Boulle A., Tanser F., Wood R., Wools-Kaloustian K., Vreeman R., Oyaro P., Ayaya S., Nakigozi G., Musick B., Yiannoutsos C., Amorissani-Folquet M., Takassi E., Sylla M., Renner L., Malateste K., Desmonde S., Leroy V., Kurniati N., Hansudewechakul R., Nguyen L. V., Ly P. S., Truong K. H., Kariminia A., Sohn A. H., Edmonds A., Yumo H. A., Dusingize J. C., Yotebieng M., Judd A., Rojo P., Smit C., Grabar S., Warszwarski J., Chene G., Raban D., Patel K., Seage G. R., Van Dyke R. B., Oleske J., Williams P. L., Abzug M. J., Succi R., Machado D. M., Pinto J., Rouzier V., Luque M., Mejia F., Khol V., Tucker J., Kumarasamy N., Saghayam S., Chandrasekaran E., Wati D. K., Vedaswari D., Malino I. Y., Muktiarti D., Fong S. M., Lim M., Daut F., Nik Yusoff N. K., Mohamad P., Mohamed T. J., Drawis M. R., Nallusamy R., Chan K. C., Sudjaritruk T., Sirisanthana V., Aurpibul L., Oberdorfer P., Denjanta S., Watanaporn S., Kongphonoi A., Lumbiganon P., Kosalaraksa P., Tharnprisan P., Udomphanit T., Jourdain G., Puthanakit T., Anugulruengkitt S., Phadungphon C., Chokephaibulkit K., Lapphra K., Phongsamart W., Sricharoenchai S., Du Q. T., Nguyen C. H., Do V. C., Ha T. M., An V. T., Khu D. T. K., Pham A. N., Nguyen L. T., Le O. N., Ross J. L., Sethaputra C., Law M. G., Cahn P., Cesar C., Fink V., Sued O., Dell'isola E., Perez H., Valiente J., Yamamoto C., Grinsztejn B., Veloso V., Luz P., de Boni R., Wagner S. C., Friedman R., Moreira R., Ferreira F., Maia M., de Menezes Succi R. C., Barbosa Gouv E A A. F. a. T., Wolff M., Cortes C., Rodriguez M. F., Allendes G., Pape J. W., Marcelin A., Perodin C., Luque M. T., Padgett D., Madero J. S., Ramirez B. C., Belaunzaran P., Vega Y. C., Gotuzzo E., Carriquiry G., McGowan C. C., Shepherd B. E., Sterling T., Jayathilake K., Person A. K., Rebeiro P. F., Giganti M., Castilho J., Duda S. N., Maruri F., Vansell H., P E Lagie N., Gateretse P., Munezero J., Nitereka V., Niyongabo T., Twizere C., Bukuru H., Nahimana T., Biziragusenyuka J., Manyundo R. S., Atsu K., Mbuh T., Ajeh R., Benwi M., Dzudie A., Mbuh A., Ngamani M. L., Nkome V., Amadou D., Ngassam E., Pefura Yone E. W., Ewanoge A. N., Fuhngwa N., Moki C., Akele C., Kitetele F., Lelo P., Tabala M., Okitolonda E. W., Wenzi L., Diafouka M., Ekat M. H., Nsonde D. M., Mafou A., Ntarambirwa F., Tuyishimire Y., Hakizimana T., Ayinkamiye J., Mukantwali S., Kayitesi H., Uwamahoro O., Habumuremyi V., Mukamana J., Kubwimana G., Mugenzi P., Muhoza B., Munyaneza A., Ndahiro E., Nyiransabimana D., D'Amour Sinayobye J., Sugira V., Benekigeri C., Mbaraga G., Adedimeji A., Anastos K., Dilorenzo M., Murchison L., Ross J., Addison D., Baker M., Brazier E., Jones H., Kelvin E., Kulkarni S., Nash D., Tymejczyk O., Elul B., Cai X., Hoover D., Kim H. -Y., Li C., Shi Q., Lancaster K., Kuniholm M., Parcesepe A., Duda S., Kimmel A., McNairy M., Diero L., Plus A. M. P. A. T. H., Bukusi E., Ssali J., Nalugoda F., Somi G. R., Lyamuya R. E., Ngonyani K., Lugina E., Urassa M., Michael D., Zannou M. D., Poda A., Sarfo F. S., Messou E., Chenal H., Minga K. A., Bissagnene E., Tanon A., Seydi M., Patassi A. A., Koumakpai-Adeothy S. A., Renner L. A., N'gbeche S. M., Bosse C. A., Kouakou K., Folquet M. A., Eboua F. c. O. T., Traore F. D., Dabis F. c. O., Arrive E., Balestre E., Becquet R., Bernard C., Arikawa S. C., Doring A., Jaquet A., Rabourdin E., Tiendrebeogo T., Jesson J., Ekouevi D. K., Azani J. -C., Coffi E P., Gnepa G., Kouadio C. G. K., Tchounga B., Maartens G., Lettow M. V., Muhairwe J., Jores A., Kamenova K., Fox M. P., Prozesky H., Zangerle R., Touloumi G., Warszawski J., Meyer L., Krause M. M., Ghosn J., Leport C., Wittkop L., Reiss P., Wit F., Prins M., Bucher H., Gibb D., Fatkenheuer G., Del Amo J., Obel N., Thorne C., Mocroft A., Kirk O., Stephan C., Perez-Hoyos S., Hamouda O., Bartmeyer B., Chkhartishvili N., Noguera-Julian A., Antinori A., D'Arminio Monforte A., Brockmeyer N., Prieto L., Conejo P. R., Soriano-Arandes A., Battegay M., Kouyos R., Mussini C., Tookey P., Casabona J., Miro J. M., Castagna A., Konopnick D., Goetghebuer T., Sonnerborg A., Torti C., Sabin C., Teira R., Garrido M., Haerry D., de Wit S., Costagliola D., Raben D., Barger D., Schwimmer C., Termote M., Campbell M., Frederiksen C. M., Friis-Moller N., Kjaer J., Brandt R. S., Berenguer J., Bohlius J., Bouteloup V., Cozzi-Lepri A., Dorrucci M., Dunn D., Furrer H., Guiguet M., Lambotte O., Lodi S., Matheron S., Miro J. M. a., Monge S., Nakagawa F., Paredes R., Phillips A., Puoti M., Rohner E., Schomaker M., Sterne J., Thiebaut R., van der Valk M., Hazra R., Heckman B., O'gara E., Siminski S., Panayidou, K, Davies, M, Anderegg, N, Egger, M, Fatti, G, Vinikoor, M, Sawry, S, Ehmer, J, Eley, B, Phiri, S, Technau, K, Chimbetete, C, Rabie, H, Boulle, A, Tanser, F, Wood, R, Wools-Kaloustian, K, Vreeman, R, Oyaro, P, Ayaya, S, Nakigozi, G, Musick, B, Yiannoutsos, C, Amorissani-Folquet, M, Takassi, E, Sylla, M, Renner, L, Malateste, K, Desmonde, S, Leroy, V, Kurniati, N, Hansudewechakul, R, Nguyen, L, Ly, P, Truong, K, Kariminia, A, Sohn, A, Edmonds, A, Yumo, H, Dusingize, J, Yotebieng, M, Judd, A, Rojo, P, Smit, C, Grabar, S, Warszwarski, J, Chene, G, Raban, D, Patel, K, Seage, G, Van Dyke, R, Oleske, J, Williams, P, Abzug, M, Succi, R, Machado, D, Pinto, J, Rouzier, V, Luque, M, Mejia, F, Khol, V, Tucker, J, Kumarasamy, N, Saghayam, S, Chandrasekaran, E, Wati, D, Vedaswari, D, Malino, I, Muktiarti, D, Fong, S, Lim, M, Daut, F, Nik Yusoff, N, Mohamad, P, Mohamed, T, Drawis, M, Nallusamy, R, Chan, K, Sudjaritruk, T, Sirisanthana, V, Aurpibul, L, Oberdorfer, P, Denjanta, S, Watanaporn, S, Kongphonoi, A, Lumbiganon, P, Kosalaraksa, P, Tharnprisan, P, Udomphanit, T, Jourdain, G, Puthanakit, T, Anugulruengkitt, S, Phadungphon, C, Chokephaibulkit, K, Lapphra, K, Phongsamart, W, Sricharoenchai, S, Du, Q, Nguyen, C, Do, V, Ha, T, An, V, Khu, D, Pham, A, Le, O, Ross, J, Sethaputra, C, Law, M, Cahn, P, Cesar, C, Fink, V, Sued, O, Dell'Isola, E, Perez, H, Valiente, J, Yamamoto, C, Grinsztejn, B, Veloso, V, Luz, P, de Boni, R, Wagner, S, Friedman, R, Moreira, R, Ferreira, F, Maia, M, de Menezes Succi, R, Barbosa Gouv E A, A, Wolff, M, Cortes, C, Rodriguez, M, Allendes, G, Pape, J, Marcelin, A, Perodin, C, Padgett, D, Madero, J, Ramirez, B, Belaunzaran, P, Vega, Y, Gotuzzo, E, Carriquiry, G, Mcgowan, C, Shepherd, B, Sterling, T, Jayathilake, K, Person, A, Rebeiro, P, Giganti, M, Castilho, J, Duda, S, Maruri, F, Vansell, H, P E Lagie, N, Gateretse, P, Munezero, J, Nitereka, V, Niyongabo, T, Twizere, C, Bukuru, H, Nahimana, T, Biziragusenyuka, J, Manyundo, R, Atsu, K, Mbuh, T, Ajeh, R, Benwi, M, Dzudie, A, Mbuh, A, Ngamani, M, Nkome, V, Amadou, D, Ngassam, E, Pefura Yone, E, Ewanoge, A, Fuhngwa, N, Moki, C, Akele, C, Kitetele, F, Lelo, P, Tabala, M, Okitolonda, E, Wenzi, L, Diafouka, M, Ekat, M, Nsonde, D, Mafou, A, Ntarambirwa, F, Tuyishimire, Y, Hakizimana, T, Ayinkamiye, J, Mukantwali, S, Kayitesi, H, Uwamahoro, O, Habumuremyi, V, Mukamana, J, Kubwimana, G, Mugenzi, P, Muhoza, B, Munyaneza, A, Ndahiro, E, Nyiransabimana, D, D'Amour Sinayobye, J, Sugira, V, Benekigeri, C, Mbaraga, G, Adedimeji, A, Anastos, K, Dilorenzo, M, Murchison, L, Addison, D, Baker, M, Brazier, E, Jones, H, Kelvin, E, Kulkarni, S, Nash, D, Tymejczyk, O, Elul, B, Cai, X, Hoover, D, Kim, H, Li, C, Shi, Q, Lancaster, K, Kuniholm, M, Parcesepe, A, Kimmel, A, Mcnairy, M, Diero, L, Plus, A, Bukusi, E, Ssali, J, Nalugoda, F, Somi, G, Lyamuya, R, Ngonyani, K, Lugina, E, Urassa, M, Michael, D, Zannou, M, Poda, A, Sarfo, F, Messou, E, Chenal, H, Minga, K, Bissagnene, E, Tanon, A, Seydi, M, Patassi, A, Koumakpai-Adeothy, S, N'Gbeche, S, Bosse, C, Kouakou, K, Folquet, M, Eboua, F, Traore, F, Dabis, F, Arrive, E, Balestre, E, Becquet, R, Bernard, C, Arikawa, S, Doring, A, Jaquet, A, Rabourdin, E, Tiendrebeogo, T, Jesson, J, Ekouevi, D, Azani, J, Coffi E, P, Gnepa, G, Kouadio, C, Tchounga, B, Maartens, G, Lettow, M, Muhairwe, J, Jores, A, Kamenova, K, Fox, M, Prozesky, H, Zangerle, R, Touloumi, G, Warszawski, J, Meyer, L, Krause, M, Ghosn, J, Leport, C, Wittkop, L, Reiss, P, Wit, F, Prins, M, Bucher, H, Gibb, D, Fatkenheuer, G, Del Amo, J, Obel, N, Thorne, C, Mocroft, A, Kirk, O, Stephan, C, Perez-Hoyos, S, Hamouda, O, Bartmeyer, B, Chkhartishvili, N, Noguera-Julian, A, Antinori, A, D'Arminio Monforte, A, Brockmeyer, N, Prieto, L, Conejo, P, Soriano-Arandes, A, Battegay, M, Kouyos, R, Mussini, C, Tookey, P, Casabona, J, Miro, J, Castagna, A, Konopnick, D, Goetghebuer, T, Sonnerborg, A, Torti, C, Sabin, C, Teira, R, Garrido, M, Haerry, D, de Wit, S, Costagliola, D, Raben, D, Barger, D, Schwimmer, C, Termote, M, Campbell, M, Frederiksen, C, Friis-Moller, N, Kjaer, J, Brandt, R, Berenguer, J, Bohlius, J, Bouteloup, V, Cozzi-Lepri, A, Dorrucci, M, Dunn, D, Furrer, H, Guiguet, M, Lambotte, O, Lodi, S, Matheron, S, Monge, S, Nakagawa, F, Paredes, R, Phillips, A, Puoti, M, Rohner, E, Schomaker, M, Sterne, J, Thiebaut, R, van der Valk, M, Hazra, R, Heckman, B, O'Gara, E, Siminski, S, Panayidou K., Davies M. -A., Anderegg N., Egger M., Fatti G., Vinikoor M., Sawry S., Ehmer J., Eley B., Phiri S., Technau K. -G. u. N., Chimbetete C., Rabie H., Boulle A., Tanser F., Wood R., Wools-Kaloustian K., Vreeman R., Oyaro P., Ayaya S., Nakigozi G., Musick B., Yiannoutsos C., Amorissani-Folquet M., Takassi E., Sylla M., Renner L., Malateste K., Desmonde S., Leroy V., Kurniati N., Hansudewechakul R., Nguyen L. V., Ly P. S., Truong K. H., Kariminia A., Sohn A. H., Edmonds A., Yumo H. A., Dusingize J. C., Yotebieng M., Judd A., Rojo P., Smit C., Grabar S., Warszwarski J., Chene G., Raban D., Patel K., Seage G. R., Van Dyke R. B., Oleske J., Williams P. L., Abzug M. J., Succi R., Machado D. M., Pinto J., Rouzier V., Luque M., Mejia F., Khol V., Tucker J., Kumarasamy N., Saghayam S., Chandrasekaran E., Wati D. K., Vedaswari D., Malino I. Y., Muktiarti D., Fong S. M., Lim M., Daut F., Nik Yusoff N. K., Mohamad P., Mohamed T. J., Drawis M. R., Nallusamy R., Chan K. C., Sudjaritruk T., Sirisanthana V., Aurpibul L., Oberdorfer P., Denjanta S., Watanaporn S., Kongphonoi A., Lumbiganon P., Kosalaraksa P., Tharnprisan P., Udomphanit T., Jourdain G., Puthanakit T., Anugulruengkitt S., Phadungphon C., Chokephaibulkit K., Lapphra K., Phongsamart W., Sricharoenchai S., Du Q. T., Nguyen C. H., Do V. C., Ha T. M., An V. T., Khu D. T. K., Pham A. N., Nguyen L. T., Le O. N., Ross J. L., Sethaputra C., Law M. G., Cahn P., Cesar C., Fink V., Sued O., Dell'isola E., Perez H., Valiente J., Yamamoto C., Grinsztejn B., Veloso V., Luz P., de Boni R., Wagner S. C., Friedman R., Moreira R., Ferreira F., Maia M., de Menezes Succi R. C., Barbosa Gouv E A A. F. a. T., Wolff M., Cortes C., Rodriguez M. F., Allendes G., Pape J. W., Marcelin A., Perodin C., Luque M. T., Padgett D., Madero J. S., Ramirez B. C., Belaunzaran P., Vega Y. C., Gotuzzo E., Carriquiry G., McGowan C. C., Shepherd B. E., Sterling T., Jayathilake K., Person A. K., Rebeiro P. F., Giganti M., Castilho J., Duda S. N., Maruri F., Vansell H., P E Lagie N., Gateretse P., Munezero J., Nitereka V., Niyongabo T., Twizere C., Bukuru H., Nahimana T., Biziragusenyuka J., Manyundo R. S., Atsu K., Mbuh T., Ajeh R., Benwi M., Dzudie A., Mbuh A., Ngamani M. L., Nkome V., Amadou D., Ngassam E., Pefura Yone E. W., Ewanoge A. N., Fuhngwa N., Moki C., Akele C., Kitetele F., Lelo P., Tabala M., Okitolonda E. W., Wenzi L., Diafouka M., Ekat M. H., Nsonde D. M., Mafou A., Ntarambirwa F., Tuyishimire Y., Hakizimana T., Ayinkamiye J., Mukantwali S., Kayitesi H., Uwamahoro O., Habumuremyi V., Mukamana J., Kubwimana G., Mugenzi P., Muhoza B., Munyaneza A., Ndahiro E., Nyiransabimana D., D'Amour Sinayobye J., Sugira V., Benekigeri C., Mbaraga G., Adedimeji A., Anastos K., Dilorenzo M., Murchison L., Ross J., Addison D., Baker M., Brazier E., Jones H., Kelvin E., Kulkarni S., Nash D., Tymejczyk O., Elul B., Cai X., Hoover D., Kim H. -Y., Li C., Shi Q., Lancaster K., Kuniholm M., Parcesepe A., Duda S., Kimmel A., McNairy M., Diero L., Plus A. M. P. A. T. H., Bukusi E., Ssali J., Nalugoda F., Somi G. R., Lyamuya R. E., Ngonyani K., Lugina E., Urassa M., Michael D., Zannou M. D., Poda A., Sarfo F. S., Messou E., Chenal H., Minga K. A., Bissagnene E., Tanon A., Seydi M., Patassi A. A., Koumakpai-Adeothy S. A., Renner L. A., N'gbeche S. M., Bosse C. A., Kouakou K., Folquet M. A., Eboua F. c. O. T., Traore F. D., Dabis F. c. O., Arrive E., Balestre E., Becquet R., Bernard C., Arikawa S. C., Doring A., Jaquet A., Rabourdin E., Tiendrebeogo T., Jesson J., Ekouevi D. K., Azani J. -C., Coffi E P., Gnepa G., Kouadio C. G. K., Tchounga B., Maartens G., Lettow M. V., Muhairwe J., Jores A., Kamenova K., Fox M. P., Prozesky H., Zangerle R., Touloumi G., Warszawski J., Meyer L., Krause M. M., Ghosn J., Leport C., Wittkop L., Reiss P., Wit F., Prins M., Bucher H., Gibb D., Fatkenheuer G., Del Amo J., Obel N., Thorne C., Mocroft A., Kirk O., Stephan C., Perez-Hoyos S., Hamouda O., Bartmeyer B., Chkhartishvili N., Noguera-Julian A., Antinori A., D'Arminio Monforte A., Brockmeyer N., Prieto L., Conejo P. R., Soriano-Arandes A., Battegay M., Kouyos R., Mussini C., Tookey P., Casabona J., Miro J. M., Castagna A., Konopnick D., Goetghebuer T., Sonnerborg A., Torti C., Sabin C., Teira R., Garrido M., Haerry D., de Wit S., Costagliola D., Raben D., Barger D., Schwimmer C., Termote M., Campbell M., Frederiksen C. M., Friis-Moller N., Kjaer J., Brandt R. S., Berenguer J., Bohlius J., Bouteloup V., Cozzi-Lepri A., Dorrucci M., Dunn D., Furrer H., Guiguet M., Lambotte O., Lodi S., Matheron S., Miro J. M. a., Monge S., Nakagawa F., Paredes R., Phillips A., Puoti M., Rohner E., Schomaker M., Sterne J., Thiebaut R., van der Valk M., Hazra R., Heckman B., O'gara E., and Siminski S.

Abstract

Introduction: The CD4 cell count and percent at initiation of combination antiretroviral therapy (cART) are measures of advanced HIV disease and thus are important indicators of programme performance for children living with HIV. In particular, World Health Organization (WHO) 2017 guidelines on advanced HIV disease noted that >80% of children aged <5 years started cART with WHO Stage 3 or 4 disease or severe immune suppression. We compared temporal trends in CD4 measures at cART start in children from low-, middle- and high-income countries, and examined the effect of WHO treatment initiation guidelines on reducing the proportion of children initiating cART with advanced disease. Methods: We included children aged <16 years from the International Epidemiology Databases to Evaluate acquired immunodeficiency syndrome (AIDS) (IeDEA) Collaboration (Caribbean, Central and South America, Asia-Pacific, and West, Central, East and Southern Africa), the Collaboration of Observational HIV Epidemiological Research in Europe (COHERE), the North American Pediatric HIV/AIDS Cohort Study (PHACS) and International Maternal Pediatric Adolescent AIDS Clinical Trials (IMPAACT) 219C study. Severe immunodeficiency was defined using WHO guidelines. We used generalized weighted additive mixed effect models to analyse temporal trends in CD4 measurements and piecewise regression to examine the impact of 2006 and 2010 WHO cART initiation guidelines. Results: We included 52,153 children from fourteen low-, eight lower middle-, five upper middle- and five high-income countries. From 2004 to 2013, the estimated percentage of children starting cART with severe immunodeficiency declined from 70% to 42% (low-income), 67% to 64% (lower middle-income) and 61% to 43% (upper middle-income countries). In high-income countries, severe immunodeficiency at cART initiation declined from 45% (1996) to 14% (2012). There were annual decreases in the percentage of children with severe immuno

Published
2018

31. Climate and urbanization drive mosquito preference for humans

Author

Rose, N. H., Sylla, M., Badolo, A., Lutomiah, J., Ayala, Diego, Aribodor, O. B., Ibe, N., Akorli, J., Otoo, S., Mutebi, J. P., Kriete, A. L., Ewing, E. G., Sang, R., Gloria-Soria, A., Powell, J. R., Baker, R. E., White, B. J., Crawford, J. E., and McBride, C. S.

Subjects
parasitic diseases
Abstract

The majority of mosquito-borne illness is spread by a few mosquito species that have evolved to specialize in biting humans, yet the precise causes of this behavioral shift are poorly understood. We address this gap in the arboviral vector Aedes aegypti. We first collect and characterize the behavior of mosquitoes from 27 sites scattered across the species' ancestral range in sub-Saharan Africa, revealing previously unrecognized variation in preference for human versus animal odor We then use modeling to show that over 80% of this variation can be predicted by two ecological factors-dry season intensity and human population density. Finally, we integrate this information with whole-genome sequence data from 375 individual mosquitoes to identify a single underlying ancestry component linked to human preference. Genetic changes associated with human specialist ancestry were concentrated in a few chromosomal regions. Our findings suggest that human-biting in this important disease vector originally evolved as a by-product of breeding in human-stored water in areas where doing so provided the only means to survive the long, hot dry season. Our model also predicts that the rapid urbanization currently taking place in Africa will drive further mosquito evolution, causing a shift toward human-biting in many large cities by 2050.

Published
2020

33. Invasive &lt;i&gt;Haemophilus influenzae&lt;/i&gt; Type b (Hib) Infections in Children in the Pediatric Department of the University Hospital Gabriel Touré (UH-GT)

Author

Maiga, B., primary, Diakité, A. A., additional, Sacko, K., additional, Sylla, M., additional, Maiga, M., additional, Cissé, M. E., additional, Dembélé, A., additional, Traoré, F., additional, Konaté, D., additional, Diakité, F. L., additional, Sidibé, L., additional, Doumbia, A. K., additional, Coulibaly, O., additional, Togo, P., additional, Touré, A., additional, Traoré, K., additional, Maiga, L., additional, Ibrahim, A., additional, Diall, H., additional, Doumbia, A., additional, Konare, H., additional, Sagara, S., additional, Niakaté, M., additional, and Cissouma, A., additional

Published
2021
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34. Ab initio and DFT study of the geometric structures and static dipole (hyper)polarizabilities of aromatic anions

Author

Castellano O., Bermudez, Y., Giffard, M., Mabon, G., Cubillan, N., Sylla, M., X. Nguyen-Phu, Hinchliffe, A., and Soscun, H.

Subjects
Density functionals -- Usage, Aromatic compounds -- Atomic properties, Anions -- Atomic properties, Polarization (Nuclear physics) -- Analysis, Chemicals, plastics and rubber industries
Abstract

The study of properties of aromatic anion species, which is of fundamental importance, is carried out, to understand the relationships between proton transfer in self-assembled monolayers on metal surfaces and nonlinear optical properties in solution and in crystals. Results of polarizabilities of aromatic anions have shown that benzenesulfinate is an anion with exceptional values for beta and that the benzenethiolate shows large values of gamma compared with the rest of anions.

Published
2005

36. Hematological Profile of Newborns Hospitalized for Neonatal Bacterial Infection in the Neonatology of the Pediatric Department of Gabriel Toure Teaching Hospital Bamako, Mali

Author

Diakité, F. L. F., primary, Diakité, A. A., additional, Coulibaly, O., additional, Diall, H., additional, Bocoum, A., additional, Sidibé, L. N., additional, Konaté, D., additional, Sacko, K., additional, Maiga, B., additional, Traoré, F., additional, Togo, P., additional, Dembélé, A., additional, Doumbia, A. K., additional, Traoré, N. L., additional, Konaré, H., additional, Cissé, M. E., additional, Touré, A., additional, Coulibaly, Y. A., additional, Sylla, M., additional, Baby, M., additional, and Dicko-Traoré, F., additional

Published
2020
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37. Etiology of Pediatric Jaundice: Observation in the Pediatric Ward of the Gabriel Toure University Hospital

Author

Sacko, K., primary, Diakité, A. A., additional, Traoré, F., additional, Maiga, B., additional, Togo, P., additional, Coulibaly, O., additional, Guindo, G., additional, Konaté, D., additional, Doumbia, A. K., additional, Konaré, H., additional, Sagara, S., additional, Dembélé, A., additional, Touré, A., additional, Diakité, F. L., additional, Sidibé, L. N., additional, Diall, H., additional, Traoré, M., additional, Coulibaly, Y. A., additional, Cissé, M. E., additional, Sangaré, A., additional, Ibrahim, A., additional, Dicko, F. T., additional, Sylla, M., additional, and Togo, B., additional

Published
2020
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38. Les facteurs influençant les indicateurs de performance à l'URENI de la pédiatrie du CHU Gabriel Touré

Author

Diall, H, primary, Dembélé, A, additional, Touré, YI, additional, Maïga, B, additional, Cissé, ME, additional, Doumbia, AK, additional, Coulibaly, O, additional, Togo, P, additional, Sacko, K, additional, Konaté, D, additional, Diakité, AA, additional, Sylla, M, additional, Dicko, F, additional, Togo, B, additional, Traoré, I, additional, Touré, A, additional, Doumbia, A, additional, Coulibaly, YA, additional, Maïga, LB, additional, Sanogo, T, additional, and Cissé, I, additional

Published
2019
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40. Global temporal changes in the proportion of children with advanced disease at the start of combination antiretroviral therapy in an era of changing criteria for treatment initiation

Author

Panayidou K., Davies M. -A., Anderegg N., Egger M., Fatti G., Vinikoor M., Sawry S., Ehmer J., Eley B., Phiri S., Technau K. -G. u. N., Chimbetete C., Rabie H., Boulle A., Tanser F., Wood R., Wools-Kaloustian K., Vreeman R., Oyaro P., Ayaya S., Nakigozi G., Musick B., Yiannoutsos C., Amorissani-Folquet M., Takassi E., Sylla M., Renner L., Malateste K., Desmonde S., Leroy V., Kurniati N., Hansudewechakul R., Nguyen L. V., Ly P. S., Truong K. H., Kariminia A., Sohn A. H., Edmonds A., Yumo H. A., Dusingize J. C., Yotebieng M., Judd A., Rojo P., Smit C., Grabar S., Warszwarski J., Chene G., Raban D., Patel K., Seage G. R., Van Dyke R. B., Oleske J., Williams P. L., Abzug M. J., Succi R., Machado D. M., Pinto J., Rouzier V., Luque M., Mejia F., Khol V., Tucker J., Kumarasamy N., Saghayam S., Chandrasekaran E., Wati D. K., Vedaswari D., Malino I. Y., Muktiarti D., Fong S. M., Lim M., Daut F., Nik Yusoff N. K., Mohamad P., Mohamed T. J., Drawis M. R., Nallusamy R., Chan K. C., Sudjaritruk T., Sirisanthana V., Aurpibul L., Oberdorfer P., Denjanta S., Watanaporn S., Kongphonoi A., Lumbiganon P., Kosalaraksa P., Tharnprisan P., Udomphanit T., Jourdain G., Puthanakit T., Anugulruengkitt S., Phadungphon C., Chokephaibulkit K., Lapphra K., Phongsamart W., Sricharoenchai S., Du Q. T., Nguyen C. H., Do V. C., Ha T. M., An V. T., Khu D. T. K., Pham A. N., Nguyen L. T., Le O. N., Ross J. L., Sethaputra C., Law M. G., Cahn P., Cesar C., Fink V., Sued O., Dell'isola E., Perez H., Valiente J., Yamamoto C., Grinsztejn B., Veloso V., Luz P., de Boni R., Wagner S. C., Friedman R., Moreira R., Ferreira F., Maia M., de Menezes Succi R. C., Barbosa Gouv E A A. F. a. T., Wolff M., Cortes C., Rodriguez M. F., Allendes G., Pape J. W., Marcelin A., Perodin C., Luque M. T., Padgett D., Madero J. S., Ramirez B. C., Belaunzaran P., Vega Y. C., Gotuzzo E., Carriquiry G., McGowan C. C., Shepherd B. E., Sterling T., Jayathilake K., Person A. K., Rebeiro P. F., Giganti M., Castilho J., Duda S. N., Maruri F., Vansell H., P E Lagie N., Gateretse P., Munezero J., Nitereka V., Niyongabo T., Twizere C., Bukuru H., Nahimana T., Biziragusenyuka J., Manyundo R. S., Atsu K., Mbuh T., Ajeh R., Benwi M., Dzudie A., Mbuh A., Ngamani M. L., Nkome V., Amadou D., Ngassam E., Pefura Yone E. W., Ewanoge A. N., Fuhngwa N., Moki C., Akele C., Kitetele F., Lelo P., Tabala M., Okitolonda E. W., Wenzi L., Diafouka M., Ekat M. H., Nsonde D. M., Mafou A., Ntarambirwa F., Tuyishimire Y., Hakizimana T., Ayinkamiye J., Mukantwali S., Kayitesi H., Uwamahoro O., Habumuremyi V., Mukamana J., Kubwimana G., Mugenzi P., Muhoza B., Munyaneza A., Ndahiro E., Nyiransabimana D., D'Amour Sinayobye J., Sugira V., Benekigeri C., Mbaraga G., Adedimeji A., Anastos K., Dilorenzo M., Murchison L., Ross J., Addison D., Baker M., Brazier E., Jones H., Kelvin E., Kulkarni S., Nash D., Tymejczyk O., Elul B., Cai X., Hoover D., Kim H. -Y., Li C., Shi Q., Lancaster K., Kuniholm M., Parcesepe A., Duda S., Kimmel A., McNairy M., Diero L., Plus A. M. P. A. T. H., Bukusi E., Ssali J., Nalugoda F., Somi G. R., Lyamuya R. E., Ngonyani K., Lugina E., Urassa M., Michael D., Zannou M. D., Poda A., Sarfo F. S., Messou E., Chenal H., Minga K. A., Bissagnene E., Tanon A., Seydi M., Patassi A. A., Koumakpai-Adeothy S. A., Renner L. A., N'gbeche S. M., Bosse C. A., Kouakou K., Folquet M. A., Eboua F. c. O. T., Traore F. D., Dabis F. c. O., Arrive E., Balestre E., Becquet R., Bernard C., Arikawa S. C., Doring A., Jaquet A., Rabourdin E., Tiendrebeogo T., Jesson J., Ekouevi D. K., Azani J. -C., Coffi E P., Gnepa G., Kouadio C. G. K., Tchounga B., Maartens G., Lettow M. V., Muhairwe J., Jores A., Kamenova K., Fox M. P., Prozesky H., Zangerle R., Touloumi G., Warszawski J., Meyer L., Krause M. M., Ghosn J., Leport C., Wittkop L., Reiss P., Wit F., Prins M., Bucher H., Gibb D., Fatkenheuer G., Del Amo J., Obel N., Thorne C., Mocroft A., Kirk O., Stephan C., Perez-Hoyos S., Hamouda O., Bartmeyer B., Chkhartishvili N., Noguera-Julian A., Antinori A., D'Arminio Monforte A., Brockmeyer N., Prieto L., Conejo P. R., Soriano-Arandes A., Battegay M., Kouyos R., Mussini C., Tookey P., Casabona J., Miro J. M., Castagna A., Konopnick D., Goetghebuer T., Sonnerborg A., Torti C., Sabin C., Teira R., Garrido M., Haerry D., de Wit S., Costagliola D., Raben D., Barger D., Schwimmer C., Termote M., Campbell M., Frederiksen C. M., Friis-Moller N., Kjaer J., Brandt R. S., Berenguer J., Bohlius J., Bouteloup V., Cozzi-Lepri A., Dorrucci M., Dunn D., Furrer H., Guiguet M., Lambotte O., Lodi S., Matheron S., Miro J. M. ª., Monge S., Nakagawa F., Paredes R., Phillips A., Puoti M., Rohner E., Schomaker M., Sterne J., Thiebaut R., van der Valk M., Hazra R., Heckman B., O'gara E., Siminski S., Panayidou, K, Davies, M, Anderegg, N, Egger, M, Fatti, G, Vinikoor, M, Sawry, S, Ehmer, J, Eley, B, Phiri, S, Technau, K, Chimbetete, C, Rabie, H, Boulle, A, Tanser, F, Wood, R, Wools-Kaloustian, K, Vreeman, R, Oyaro, P, Ayaya, S, Nakigozi, G, Musick, B, Yiannoutsos, C, Amorissani-Folquet, M, Takassi, E, Sylla, M, Renner, L, Malateste, K, Desmonde, S, Leroy, V, Kurniati, N, Hansudewechakul, R, Nguyen, L, Ly, P, Truong, K, Kariminia, A, Sohn, A, Edmonds, A, Yumo, H, Dusingize, J, Yotebieng, M, Judd, A, Rojo, P, Smit, C, Grabar, S, Warszwarski, J, Chene, G, Raban, D, Patel, K, Seage, G, Van Dyke, R, Oleske, J, Williams, P, Abzug, M, Succi, R, Machado, D, Pinto, J, Rouzier, V, Luque, M, Mejia, F, Khol, V, Tucker, J, Kumarasamy, N, Saghayam, S, Chandrasekaran, E, Wati, D, Vedaswari, D, Malino, I, Muktiarti, D, Fong, S, Lim, M, Daut, F, Nik Yusoff, N, Mohamad, P, Mohamed, T, Drawis, M, Nallusamy, R, Chan, K, Sudjaritruk, T, Sirisanthana, V, Aurpibul, L, Oberdorfer, P, Denjanta, S, Watanaporn, S, Kongphonoi, A, Lumbiganon, P, Kosalaraksa, P, Tharnprisan, P, Udomphanit, T, Jourdain, G, Puthanakit, T, Anugulruengkitt, S, Phadungphon, C, Chokephaibulkit, K, Lapphra, K, Phongsamart, W, Sricharoenchai, S, Du, Q, Nguyen, C, Do, V, Ha, T, An, V, Khu, D, Pham, A, Le, O, Ross, J, Sethaputra, C, Law, M, Cahn, P, Cesar, C, Fink, V, Sued, O, Dell'Isola, E, Perez, H, Valiente, J, Yamamoto, C, Grinsztejn, B, Veloso, V, Luz, P, de Boni, R, Wagner, S, Friedman, R, Moreira, R, Ferreira, F, Maia, M, de Menezes Succi, R, Barbosa Gouv E A, A, Wolff, M, Cortes, C, Rodriguez, M, Allendes, G, Pape, J, Marcelin, A, Perodin, C, Padgett, D, Madero, J, Ramirez, B, Belaunzaran, P, Vega, Y, Gotuzzo, E, Carriquiry, G, Mcgowan, C, Shepherd, B, Sterling, T, Jayathilake, K, Person, A, Rebeiro, P, Giganti, M, Castilho, J, Duda, S, Maruri, F, Vansell, H, P E Lagie, N, Gateretse, P, Munezero, J, Nitereka, V, Niyongabo, T, Twizere, C, Bukuru, H, Nahimana, T, Biziragusenyuka, J, Manyundo, R, Atsu, K, Mbuh, T, Ajeh, R, Benwi, M, Dzudie, A, Mbuh, A, Ngamani, M, Nkome, V, Amadou, D, Ngassam, E, Pefura Yone, E, Ewanoge, A, Fuhngwa, N, Moki, C, Akele, C, Kitetele, F, Lelo, P, Tabala, M, Okitolonda, E, Wenzi, L, Diafouka, M, Ekat, M, Nsonde, D, Mafou, A, Ntarambirwa, F, Tuyishimire, Y, Hakizimana, T, Ayinkamiye, J, Mukantwali, S, Kayitesi, H, Uwamahoro, O, Habumuremyi, V, Mukamana, J, Kubwimana, G, Mugenzi, P, Muhoza, B, Munyaneza, A, Ndahiro, E, Nyiransabimana, D, D'Amour Sinayobye, J, Sugira, V, Benekigeri, C, Mbaraga, G, Adedimeji, A, Anastos, K, Dilorenzo, M, Murchison, L, Addison, D, Baker, M, Brazier, E, Jones, H, Kelvin, E, Kulkarni, S, Nash, D, Tymejczyk, O, Elul, B, Cai, X, Hoover, D, Kim, H, Li, C, Shi, Q, Lancaster, K, Kuniholm, M, Parcesepe, A, Kimmel, A, Mcnairy, M, Diero, L, Plus, A, Bukusi, E, Ssali, J, Nalugoda, F, Somi, G, Lyamuya, R, Ngonyani, K, Lugina, E, Urassa, M, Michael, D, Zannou, M, Poda, A, Sarfo, F, Messou, E, Chenal, H, Minga, K, Bissagnene, E, Tanon, A, Seydi, M, Patassi, A, Koumakpai-Adeothy, S, N'Gbeche, S, Bosse, C, Kouakou, K, Folquet, M, Eboua, F, Traore, F, Dabis, F, Arrive, E, Balestre, E, Becquet, R, Bernard, C, Arikawa, S, Doring, A, Jaquet, A, Rabourdin, E, Tiendrebeogo, T, Jesson, J, Ekouevi, D, Azani, J, Coffi E, P, Gnepa, G, Kouadio, C, Tchounga, B, Maartens, G, Lettow, M, Muhairwe, J, Jores, A, Kamenova, K, Fox, M, Prozesky, H, Zangerle, R, Touloumi, G, Warszawski, J, Meyer, L, Krause, M, Ghosn, J, Leport, C, Wittkop, L, Reiss, P, Wit, F, Prins, M, Bucher, H, Gibb, D, Fatkenheuer, G, Del Amo, J, Obel, N, Thorne, C, Mocroft, A, Kirk, O, Stephan, C, Perez-Hoyos, S, Hamouda, O, Bartmeyer, B, Chkhartishvili, N, Noguera-Julian, A, Antinori, A, D'Arminio Monforte, A, Brockmeyer, N, Prieto, L, Conejo, P, Soriano-Arandes, A, Battegay, M, Kouyos, R, Mussini, C, Tookey, P, Casabona, J, Miro, J, Castagna, A, Konopnick, D, Goetghebuer, T, Sonnerborg, A, Torti, C, Sabin, C, Teira, R, Garrido, M, Haerry, D, de Wit, S, Costagliola, D, Raben, D, Barger, D, Schwimmer, C, Termote, M, Campbell, M, Frederiksen, C, Friis-Moller, N, Kjaer, J, Brandt, R, Berenguer, J, Bohlius, J, Bouteloup, V, Cozzi-Lepri, A, Dorrucci, M, Dunn, D, Furrer, H, Guiguet, M, Lambotte, O, Lodi, S, Matheron, S, Monge, S, Nakagawa, F, Paredes, R, Phillips, A, Puoti, M, Rohner, E, Schomaker, M, Sterne, J, Thiebaut, R, van der Valk, M, Hazra, R, Heckman, B, O'Gara, E, and Siminski, S

Subjects
0301 basic medicine, Male, sub-Saharan Africa, Databases, Factual, CD4 cell count, HIV Infections, Global Health, Cohort Studies, 0302 clinical medicine, Central and South America, Advanced disease, Medicine, 030212 general & internal medicine, Prospective Studies, Cd4 cell count, skin and connective tissue diseases, Child, Research Articles, humanities, 3. Good health, Europe, Infectious Diseases, Child, Preschool, Income, Drug Therapy, Combination, Female, advanced HIV disease, antiretroviral therapy, Asia, Caribbean, North America, WHO guidelines, Adolescent, Adult, Anti-HIV Agents, CD4 Lymphocyte Count, Drug Administration Schedule, Follow-Up Studies, Humans, Poverty, World Health Organization, Research Article, medicine.medical_specialty, education, 610 Medicine & health, 03 medical and health sciences, Acquired immunodeficiency syndrome (AIDS), 360 Social problems & social services, Intensive care medicine, business.industry, Public Health, Environmental and Occupational Health, medicine.disease, 030112 virology, Antiretroviral therapy, Who guidelines, sense organs, business, sub‐Saharan Africa
Abstract

Introduction: The CD4 cell count and percent at initiation of combination antiretroviral therapy (cART) are measures of advanced HIV disease and thus are important indicators of programme performance for children living with HIV. In particular, World Health Organization (WHO) 2017 guidelines on advanced HIV disease noted that >80% of children aged 40% of children in low- and middle-income countries started cART with severe immunodeficiency compared to

Published
2018

43. Relações Públicas - Fator de Integração

Author

Sylla M. Chaves

Abstract

Em recente artigo para a "Revista do Serviço Público", defini relações públicas como "a função administrativa por meio da qual uma instituição, ora informando e guiando a opinião pública, ora pesquisando-a e deixando-se por ela guiar, busca identificar o seu interesse privado com o interesse público, desincumbindo-se de suas obrigações para com a sociedade e conseguindo e mantendo a compreensão, a aquiescência e o apoio desta”. (1) Cheguei a ela após longas considerações, apoiado em autores abalizados de vários países. Como esse artigo pode ser consultado pelos congressistas, torna-se desnecessário repetir toda a sua argumentação, embora saibamos existir quem considere relações públicas atividades menos democrática ou com menor relevância social.

Published
2017

45. Que São Relações Públicas?

Author

Sylla M. Chaves

Abstract

Este artigo corresponde ao primeiro capítulo do livro Relações Públicas, Propaganda e Opinião Pública "A n Introduction to Public Opinion”, primeira de uma série de traduções — Administração para o Desenvolvimento — que a Fundação Getúlio Vargas e a U. S. Agency for International Development estão preparando como contribuição conjunta para o esforço que cada vez mais toma corpo em nosso país. N o volume 94, nº 4 desta Revista expus as razões por que considero relações públicas um fator de integração e desenvolvimento. É preciso, porém, que os técnicos de relações públicas compreendam a importância das suas responsabilidades e correspondam ao que a sociedade espera deles. O grande problema de nosso país em desenvolvimento, em matéria de relações públicas, é, pois, ainda o da definição das responsabilidades que todos temos e que ninguém quer assumir. O importante é combinar a indiscutível força das relações públicas com o imenso potencial deste país, e pô-lo em marcha. N a indicação das responsabilidades, na indicação do caminho a seguir, é que reside a grande contribuição do livro de Childs.

Published
2017

46. O Ensino de Relações com o Público

Author

Sylla M. Chaves

Abstract

Desde os primeiros tempos do DASP, a administração pública tem-se ocupado da utilização das ciências sociais para o aperfeiçoamento do ambiente humano, interno e externo. O pais foi, então, começando a utilizar, às vezes confusamente, as expressões relações humanas, relações públicas e relações com o público. A etimologia não permite distingui-las claramente. A prática, entretanto, tem demonstrado existirem, na administração, pelo menos três atividades completamente distintas que podem ser denominadas «relações»; a cada uma delas corresponde uma das expressões acima mencionadas.

Published
2017

48. ARMA model for short-term forecasting of solar potential ARMA model for short-term forecasting of solar potential: application to a horizontal surface on Dakar site A. Mbaye et al, ARMA model for short-term forecasting of solar potential

Author

Mbaye, A., Ndiaye, Mamadou, Ndione, D, Diaw, M, Traoré, V, Ndiaye, A, Sylla, M., Aidara, M, Diaw, V, Traoré, A., Ndiaye, P., Université Cheikh Anta Diop [Dakar, Sénégal] (UCAD), Laboratoire de Biophotonique et Pharmacologie - UMR 7213 (LBP), Centre National de la Recherche Scientifique (CNRS)-Réseau nanophotonique et optique, Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA))-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Université de Haute-Alsace (UHA) Mulhouse - Colmar (Université de Haute-Alsace (UHA)), Propriétés Optiques des Matériaux et Applications (POMA), Centre National de la Recherche Scientifique (CNRS)-Université d'Angers (UA), and Institut Fondamental d'Afrique Noire (IFAN)

Subjects
FORECASTING, STOCHASTIC, [PHYS.COND.CM-MS]Physics [physics]/Condensed Matter [cond-mat]/Materials Science [cond-mat.mtrl-sci], SOLAR RADIATION, DAKAR, ARMA
Abstract

International audience; This paper presents a model for short-term forecasting of solar potential on a horizontal surface. This study is carried out in to the context of valuing of energy production from photovoltaic solar sources in the Sahelian zone. In this study, Autoregressive Moving Average (ARMA) process is applied to predict global solar potential upon 24 hours ahead. The ARMA (p, q) is based on finding optimum parameters p and q to better fit considered variable (sunshine). Data used for the model calibrating are measured at the station of Ecole Supérieure Polytechnique of Dakar. Records are hourly and range from October 2016 to September 2017. The choice of this model is justified by its robustness and its applicability on several scales through the world. Simulation is done using the RStudio software. The Akaike information criterion shows that ARMA (29, 0) gives the best representation of the data. We then applied a white noise test to validate the process. It confirms that the noise is of white type with zero mean, variance of 1.252 and P-value of about 26% for a significant level of 5%. Verification of the model is done by analyzing some statistical performance criteria such the RMSE =0.629 (root mean squared error), the R² = 0.963 (Coefficient of determination), the MAE=0.528 (Mean Absolut Error) and the MBE=0.012 (Mean Bias Error). Statistics criteria show that the ARMA (29,0) is reliable;then, can help to improve planning of photovoltaic solar power plants production in the Sahelian zone.

Published
2019

49. International conference ICAWA 2017 and 2018 : extended book of abstract : the AWA project : ecosystem approach to the management of fisheries and the marine environment in West African waters

Author

Diadhiou, H.D., Ndiaye, N.A., Diagne, H.M., Ndiaye, W., Diedhiou, F., Niang, M., Sylla, M., Gaye, M.L., Fall, S., Brehmer, Patrice, Brehmer, Patrice (ed.), Diogoul, N. (collab.), Zenk, C. (collab.), Vareilles, M. de (collab.), Keenlyside, N. (collab.), Nascimento, J.M. (collab.), Ramos, V. M. (collab.), Sow, B.A. (collab.), Fock, H. (collab.), Schmidt, J. (collab.), Ekau, W. (collab.), Mbaye, A. (collab.), Fall. A. (collab.), Monteiro, I. (collab.), Kouassi, A.M. (collab.), Silva, O. (collab.), Brochier, Timothée (collab.), Sall. M. (collab.), Mayif, M. (collab.), Koné, V. (collab.), Gorgues, Thomas (collab.), Ferreira Santos, C. (collab.), Bamy, I.L. (collab.), Barry, I. (collab.), Sidibe, M. (collab.), and Diadhou, H. (collab.)

Abstract

All predictions agree that tilapia is destined to become the major aquaculture species of tomorrow. Tilapia is grown in more than 100 countries and production reaches 4.3 million tonnes making this fish group the second largest for global aquaculture, after that of carp. The modern development of its breeding requires energy for production systems e.g. to supply oxygen equipment or automatic food vending machines or the heating of livestock ponds. This work proposes to valorise the waste resulting from the activities in fish farming by the processes of anaerobic digestion to produce energy. For this, faeces of Tilapia Oreochromis niloticus were sampled periodically and their methanogenic potential (BMP test) determined and compared to a reference substrate (poultry droppings); with or without inoculum. The μCG analysis made it possible to determine the relative proportions of methane (CH4) in the biogas as a function of the duration of production. Biochemical methane potential (BMP) tests showed rapid kinetics of biogas production of fish faeces in the presence of inoculum (+ inoculum) compared with the production of biogas in faeces alone. This kinetics of biogas production is reversed between the third and fourth week. In both cases, the proportion of methane is generally greater than 60% from the second week of incubation, which shows the quality of the biogas produced. The composition of CH4 and CO2 does not change with or without inoculum. However, there is a significant difference in total CH4 volume which is twice as large with inoculated fish faeces than uninoculated fish or poultry droppings. Our results show that fish droppings are good methanogenic substrates and the use of the inoculum allows for a quick start of biogas production and avoids MO losses. Realized on a large scale, the valorisation of aquaculture fish faeces could constitute a source of green energy for the development of fish farming in Africa. And thus a smart initiative to fight against climate impact on small pelagic fish stock displacement in tropical areas.

Published
2019

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