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Background: Determination of the electrocardiographic changes among the hypertensive patients can reveal the early cardiac abnormalities especially of left ventricular hypertrophy. Objectives : The purpose of the present study was to find out the P and QRS waves of electrocardiographic (ECG) changes in different grades of hypertensive patients. Methodology: This cross sectional study was conducted among mild to severe grade hypertensive patients attended in the Department of Medicine at Rajshahi Medical College and Hospital, Rajshahi during the period of July 2009 to June 2010 for a period of one year. Data were collected by face to face interview with a pre-designed structured questionnaire. Measurement of the blood pressure and the 12-lead surface electrocardiogram were done among the study group in a resting state. Results: A total number of 400 hypertensive patients were recruited for this study. In mild hypertension, high voltage QRS complex was noted as the main ECG abnormality (24.8%) which was followed by wide P-wave (15.2%). In moderate hypertension, the high voltage QRS complex was 31.0%, wide P wave 25.0%. In severe hypertension, wide P wave and high voltage QRS complex were 56.0%and 20.0% cases respectively. Chi-square test was done between category of hypertension and ECG changes of the study group. The results were statistically highly significant (p

Background: Anaemia is a common health problem encountered in our day to day medical practice. It occurs in every age groups, in both sexes in every communities and all countries. Objective: To find out the aetiological pattern and clinical profile of severe anaemia for prompt diagnosis an droper management. Materials and Methods: The prospective study was carried out in different Medicine unit at Rajshahi Medical College Hospital (RMCH), Rajshahi on consecutive 100 hospital admitted patients having severe anaemia. All underwent routine and some special investigations for severe anaemia. Results: Peak age incidence was 20-29 years (38%) and sex incidence was male (68%). Most of the patients were farmers (38%). Common monthly income group was >2000-5000 (48%). Incidence of severe anaemia was aplastic (26%), leukaemia (24%), haemolytic (22%), anaemia of chronic disorder (10%), iron deficiency anaemia (9%) and anaemia of chronic renal failure (9%). Peak age incidence for aplastic anaemia was 20- 29 years (42.3%), for leukaemia 14-19 years 33.3%), for haemolytic anaemia 14-19 years (50%), for anaemia of chronic disorder 20-29 and 30-39 years (30% each), iron deficiency anaemia 40-49 years (44.5%) and for anaemia of chronic renal failure 30-39 years (33.3%). Conclusion: Multicentre study with large sample size is warrented to develop more insights about diagnosis and management of severe anaemia. KYAMC Journal Vol. 6, No.-2, Jan 2016, Page 631-636

Drug addiction and drug abuse, chronic or habitual use of any chemical substance to alter states of body or mind for other than medically warranted purposes. Addiction is more often now defined by the continuing, compulsive nature of the drug use despite physical and/or psychological harm to the user and society and includes both licit and illicit drugs, and the term "substance abuse" is now frequently used because of the broad range of substances (including alcohol and inhalants) that can fit the addictive profile. Psychological dependence is the subjective feeling that the user needs the drug to maintain a feeling of well-being; physical dependence is characterized by tolerance (the need for increasingly larger doses in order to achieve the initial effect) and withdrawal symptoms when the user is abstinent. There are a lot of effects of drug addiction to the economy, society, and family. Drug addiction affects individual's physical and mental health. Drug addicts are burden for a family and society. It is a great challenge for all nations of the world to prevent drug addiction. This article reviews the effects of drug addiction in details. DOI: http://dx.doi.org/10.3329/medtoday.v25i2.17927 Medicine Today 2013 Vol.25(2): 84-89