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Background: Since the majority of GBM patients are aware that there is no known cure, it makes sense that they would want to know about complementary, alternative, and CIM therapies. Methods: This systematic review focused on full-text English literature published between 2014 and 2024 using the PRISMA 2020 guidelines. The literature was compiled using PubMed, ScienceDirect, and SagePub, among other online venues. Result: Five publications were found to be directly related to our ongoing systematic examination after a rigorous three-level screening approach. Conclusion: complementary and alternative medicine methods to comfor patients with gliomas with the medication side effects that taking control of the disease. The findings of this systematic review helped to educate the providers and patients to stimulate more research according to complementary and alternative medicine for treatment of gliomas.

Background: While traditional wide-incision approaches pose risks of long-term spinal instability, minimally invasive techniques, increasingly favored since the late 1990s, require further investigation regarding their safety and efficacy compared to open approaches for Intradural extramedullar (ID-EM) tumor resection. Methods: This systematic review focused on full-text English literature published between 2014 and 2024 using the PRISMA 2020 guidelines. The literature was compiled using PubMed, ScienceDirect, and SagePub, among other online venues. Result: Employing a meticulous three-tier screening approach, we identified only five papers that were directly pertinent to our ongoing systematic assessment. Subsequently, we conducted a comprehensive examination of the entire text and further selected articles; retrospective study, retrospective analysis, retrospective observational study; comparative, prospective cohort, and retrospective cohort study. Conclusion: The minimally invasive transspinous approach demonstrates safety and efficacy comparable to open surgery, with reduced intraoperative blood loss, but further randomized studies are needed to assess their cost-effectiveness and wider adoption. Although minimally invasive tubular retractor surgery shows favorable outcomes, particularly in reducing postoperative paraspinal muscle fatty degeneration and analgesic consumption, larger studies are warranted to confirm its long-term effects on pain reduction and patient outcomes. As these techniques gain traction, their potential benefits in improving patient care will become increasingly apparent.