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This paper proposes a modeling approach for biodegradation of implant-bone scaffolds. A Computer simulation was performed to determine the wall shear stress (WSS) and permeability of simulated body fluid (SBF) with a constant flow rate of 0.025 ml/min. In this study, four morphological samples were used to immersion time from 0 to 72 hours. Each specimen was given a different bone strain (1000-3500 μstrain) which created a variation of displacement in the bone scaffold. The method used in the simulation was the fluid-structure interaction (FSI). The pressure drop through the specimen decreases linearly, the permeability increases as the porosity increases, and the mean wall shear stress decreases due to the length of the immersion time. It was obtained that the permeability values of the implant-bone scaffold increases from 7.79×10-10 m2 to 1.09×10-9 m2 and the mean shear stress values decrease from 2.86×10-3 Pa to 1.38×10-3 Pa.

The purpose of this study is to analyze the influence of morphology on the degrading behavior of porous magnesium bone scaffold by using computer simulation. Based on the experimental work, the three bone scaffold prepared with 30%, 41%, and 55% of porosity, respectively. The bone scaffold made of pure magnesium that immersed in simulated body fluid (SBF) for 72 hours with constant flow rates of 0.025 ml/min. After degradation, each specimen was scanned by μCT with a resolution of 17 μm. In this study, three different morphology before and after degradation was performed by computer simulation using the FSI method. Each specimen before and after degradation were given different bone strain (1000-3500 μstrain) that create displacement variations on the bone scaffold. Before degradation, the outcomes showed that the variation of displacement affects fluid characteristic change and for the specimen C (55% of porosity) generates the highest permeability with the value of 8.78 × 10-10 m2. After degradation, specimen A (30% of porosity) has a higher average shear stress of 2.04 × 10-3 Pa, specimen C (55% of porosity) has degradation rate of 3.37 mg/cm2/d and the highest porosity of 75.81%.