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Mucinous Cystadenocarcinoma (MCA) of the breast is a rare variant of primary breast cancer with an unknown aetiology and pathogenesis. It resembles MCA of the ovary and pancreas and accounts for about one to four percent of primary breast cancers. Less than 25 cases of primary breast MCA have been reported in the literature. These tumours belong to the family of mucin-producing carcinomas of the breast, which includes mucinous carcinoma, signet ring cell carcinoma, columnar cell mucinous carcinoma, and MCA. MCA presents as a well-circumscribed, solid, and cystic mass. It contains large cystic spaces filled with mucin and is lined by atypical columnar cells with intracytoplasmic mucin. In addition to routine examination of haematoxylin and eosin-stained slides, immunohistochemistry is necessary for the accurate diagnosis of primary breast MCA and to differentiate it from pure mucinous carcinoma. These tumours typically do not expresshormonal receptors, making them triple-negative. We report a case of a 49-year-old woman who presented with a lump in her left breast. Ultrasonography suggested the possibility of carcinoma or atypical fibroadenoma. Fine Needle Aspiration Cytology (FNAC) indicated features suggestive of carcinoma. A trucut biopsy revealed infiltrating ductal carcinoma with mucinous features. Subsequently, a left-modified radical mastectomy was performed, and the patient was diagnosed with mixed-type carcinoma, comprising an 80-85% MCA component and a 15-20% invasive ductal carcinoma component.

Pure mesenchymal sarcomas and phyllodes tumor with sarcomatous differentiation of the breast are rare tumors. Primary breast sarcomas are a heterogenous group of neoplasms which include malignant fibrous histiocytoma, fibrosarcoma, angiosarcoma, leiomyosarcoma, osteosarcoma, rhabdomyosarcoma, and liposarcoma. Sarcomatous differentiation in phyllodes tumor is seen in the form of angiosarcoma, chondrosarcoma, leiomyosarcoma, osteosarcoma, rhabdomyosarcoma, and liposarcoma. Here, we report a case of a 28-year-old pregnant woman with a breast lump during her second trimester which drastically increased in size in the postpartum period. Wide local excision revealed a malignant phyllodes tumor with liposarcomatous differentiation. Later, the patient underwent completion mastectomy which showed residual tumor.

Primary Bone Lymphomas (PBLs) are uncommon. Most of these tumours are Non Hodgkin Lymphoma (NHL) with Diffuse Large B-cell Lymphoma (DLBCL) being the most common. Anaplastic Large Cell Lymphoma (ALCL) constitutes approximately 2% of all NHL and involves both nodal and extra nodal sites. ALCL presenting as exclusive and extensive bone involvement is rare. We report a case of 31-year-old man who presented with osseous involvement only. Imaging showed multiple lytic lesions involving the vertebral column, ribs and sternum. Clinical differential diagnosis included osteomyelitis and bone neoplasms. Histopathology and immunohistochemistry of the lytic lesion proved it to be Anaplastic Lymphoma Kinase (ALK-1) positive ALCL. The patient relapsed three months after completion of six cycles of combination chemotherapy with Cyclophosphamide, Hydroxydaunorubicin, Vincristine and Prednisone (CHOP).

Teratomas are neoplasms comprising of tissues derived from more than one germ layer. Most common sites are gonads, sacrococcygeal, mediastinal, retroperitoneal, and pineal region. Here, we report a case of 2 -year-old previously healthy female toddlerwho presented with fever and right upper quadrant abdominal pain. Magnetic resonance imaging (MRI) of the abdomen revealed a right suprarenal nonenhancing cystic mass. Focal calcification was seen in the inferomedial aspect of the cyst. Complete surgical resection of the right adrenal gland was done. The patient had an uneventful postoperative course and was free of recurrence at 8 months follow-up. Primary retroperitoneal teratomas of the adrenal gland are very uncommon (4% of all primary teratomas) and can mimic a primary adrenal tumor, hence should be included in the differential diagnosis of adrenal masses.