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A study was conducted to characterize a novel allelic series at the underwhite gene on mouse chromosome 15. The phenotypes and dominance hierarchy of the alleles were characterized by a reduction of pigmentation in eye and coat color. Results also indicated that the underwhite locus is genetically different from Myo10. In addition, Myo10 was found to be a candidate gene for underwhite because of three recombinant chromosomes between two loci.

Dense incisors (din) is an autosomal recessive mutation on chromosome 16 in the mouse that hampers eruption of the incisors. The initial eruption through the gingiva is unaffected, but the subsequent eruption stops. The inability of the incisor to erupt properly results in dentin formation that obstructs the pulp chambers producing a dense incisor. The mutation produces a mouse with an anterior open bite. The body size and ear pinna size are smaller and the coat color is duller in the mutants.

Mesenchymal dysplasia (mes) is an autosomal recessive mutation that results in abnormal growth in many mesoderm-derived tissues. The condition in mes mutation is similar to some human syndromes, and the mutation provides a mouse model for studies on connective tissue disorders. The mutation is mapped to chromosome 13, close to the genes that regulate growth. Mes mutation produces skeletal abnormalities, such as, preaxial polydactyly of all four feet, a shorter kinky tail, wide set eyes, and a shortened face.