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318 results on '"Sweeney, Alex D."'

1. Single-cell multi-omic analysis of the vestibular schwannoma ecosystem uncovers a nerve injury-like state

Author

Barrett, Thomas F., Patel, Bhuvic, Khan, Saad M., Mullins, Riley D. Z., Yim, Aldrin K. Y., Pugazenthi, Sangami, Mahlokozera, Tatenda, Zipfel, Gregory J., Herzog, Jacques A., Chicoine, Michael R., Wick, Cameron C., Durakovic, Nedim, Osbun, Joshua W., Shew, Matthew, Sweeney, Alex D., Patel, Akash J., Buchman, Craig A., Petti, Allegra A., Puram, Sidharth V., and Kim, Albert H.

Published
2024
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4. Quality of Life After Pediatric Tympanomastoidectomy.

Author

Lovin, Benjamin D., Nguyen, Aaron C., Lindquist, Nathan R., Nguyen, Duc, Silva, Rodrigo, and Sweeney, Alex D.

Subjects
MASTOIDECTOMY, OTITIS media, ACADEMIC medical centers, CHOLESTEATOMA, TREATMENT effectiveness, RETROSPECTIVE studies, TERTIARY care, DESCRIPTIVE statistics, TYMPANOPLASTY, SURVEYS, QUALITY of life, MEDICAL records, ACQUISITION of data, PLASTIC surgery
Abstract

Objectives: To assess quality of life (QOL) outcomes after canal wall up (CWU) and canal wall down (CWD) tympanomastoidectomy in the pediatric population. Methods: A retrospective review tabulated pediatric patients undergoing CWU and CWD tympanomastoidectomy for cholesteatoma by 2 senior surgeons at a single tertiary academic referral center between March 2017 and March 2023. Chronic Ear Survey (CES) and cosmetic survey outcomes were collected post-operatively. Results: A total of 77 ears in 75 patients were identified, with 35 undergoing CWU and 42 undergoing CWD as the most recent (index) otologic surgery. Seventeen patients (23%) participated in the survey. Of this cohort, the mean age was 14.6 years, 12 (71%) were male, and 10 (59%) had CWD as the most recent otologic surgery. The mean time from index surgery to survey completion was 3.4 years (range, 0.1-6.7 years). Regarding QOL outcomes, there were no statistically significant differences in total CES score, CES subscores, and cosmetic survey scores between groups when categorizing by gender or index surgery. Total CES, symptom subscale, medical resource subscale, and cosmetic survey scores showed a tendency to decrease with an increasing number of surgeries (R = −.18, −.28, −.53, and −.56, respectively). Pediatric total CES scores appeared comparable to those reported in the published adult literature. Conclusions: It does not appear that there are worse QOL outcomes for pediatric patients who undergo CWD tympanomastoidectomy compared to those who undergo CWU tympanomastoidectomy. There appears to be no difference in QOL outcomes between pediatric and adult patients undergoing tympanomastoidectomy. [ABSTRACT FROM AUTHOR]

Published
2024
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9. Multi-omic Analysis of Sporadic Vestibular Schwannoma Reveals a Nerve Injury-Like State and Novel Molecular Targets

Author

Patel, Bhuvic, additional, Barrett, Thomas F., additional, Khan, Saad M., additional, Mullens, Riley, additional, Yim, Aldrin K., additional, Pugazenthi, Sangami, additional, Mahlokozera, Tatenda, additional, Zipfel, Gregory J., additional, Herzog, Jacques A., additional, Chicoine, Michael R., additional, Wick, Cameron C., additional, Durakovic, Nedim, additional, Osbun, Joshua W., additional, Shew, Matthew, additional, Sweeney, Alex D., additional, Patel, Akash J., additional, Buchman, Craig A., additional, Petti, Allegra A., additional, Puram, Sidharth V., additional, and Kim, Albert H., additional

Published
2024
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10. Temporal Bone Paraganglioma

Author

Carlson, Matthew L., Sweeney, Alex D., Patel, Neil S., Wanna, George B., Perkins, Jonathan A., editor, and Balakrishnan, Karthik, editor

Published
2018
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13. Tympanic Paraganglioma

Author

Sweeney, Alex D., Carlson, Matthew L., Wanna, George B., editor, Carlson, Matthew L., editor, and Netterville, James L., editor

Published
2018
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14. Rationale for the Development of a Novel Clinical Grading Scale for Postoperative Facial Nerve Function: Results of a Multidisciplinary International Working Group

Author

Carlson, Matthew L., primary, Lohse, Christine M., additional, Agazzi, Siviero, additional, Babu, Seilesh C., additional, Barker, Frederick G., additional, Barnett, Samuel, additional, Bi, Wenya Linda, additional, Biggs, Nigel, additional, Boahene, Kofi D., additional, Breen, Joseph T., additional, Brown, Kevin D., additional, Cayé-Thomasen, Per, additional, Cosetti, Maura K., additional, Deep, Nicholas L., additional, Dey, Jacob K., additional, Dornhoffer, James R., additional, Forner, David, additional, Gurgel, Richard K., additional, Hansen, Marlan R., additional, Hunter, Jacob B., additional, Kalamarides, Michel, additional, Kim, Irene A., additional, King, Andrew T., additional, Kircher, Matthew L., additional, Lassaletta, Luis, additional, Link, Michael J., additional, Lloyd, Simon K.W., additional, Lund-Johansen, Morten, additional, Marinelli, John P., additional, Matthies, Cordula, additional, Mehta, Vikas, additional, Moore, Eric J., additional, Nassiri, Ashley M., additional, Neff, Brian A., additional, Nelson, Rick F., additional, Olson, Jeffrey J., additional, Patel, Neil S., additional, Celda, Maria Peris, additional, Plitt, Aaron R., additional, Price, Daniel L., additional, Thomas Roland, J., additional, Sweeney, Alex D., additional, Tasche, Kendall K., additional, Tatagiba, Marcos, additional, Tveiten, Øystein, additional, Van Gompel, Jamie J., additional, Vrabec, Jeffrey T., additional, Wanna, George B., additional, and Weisskopf, Peter A., additional

Published
2023
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27. Approach to Cochlear Implantation in Patients With Ventriculoperitoneal Shunts

Author

Macielak, Robert J., primary, Selleck, Anne Morgan, additional, Kocharyan, Armine, additional, Hunter, Jacob B., additional, Patro, Ankita, additional, Perkins, Elizabeth L., additional, Hamilton, Christopher A., additional, Patel, Neil S., additional, Gurgel, Richard K., additional, Sweeney, Alex D., additional, Brown, Kevin D., additional, Link, Michael J., additional, and Carlson, Matthew L., additional

Published
2023
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32. Single-cell multi-omic analysis of the vestibular schwannoma ecosystem uncovers a nerve injury-like state

Author

Barrett, Thomas F., primary, Patel, Bhuvic, additional, Khan, Saad M., additional, Yim, Aldrin K.Y., additional, Pugazenthi, Sangami, additional, Mahlokozera, Tatenda, additional, Mullins, Riley D.Z., additional, Zipfel, Gregory J., additional, Herzog, Jacques A., additional, Chicoine, Michael R., additional, Wick, Cameron C., additional, Durakovic, Nedim, additional, Osbun, Joshua W., additional, Shew, Matthew, additional, Sweeney, Alex D., additional, Patel, Akash J., additional, Buchman, Craig A., additional, Petti, Allegra A., additional, Puram, Sidharth V., additional, and Kim, Albert H., additional

Published
2022
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43. Quality of Life After Modified Rambo Ear Canal Closure in Pediatric and Adult Patients.

Author

You, Peng, Lovin, Benjamin D., Patel, Akash J., Hosek, Kathleen E., Peng, Angela, and Sweeney, Alex D.

Abstract

Objective: To present the surgical and quality of life (QOL) outcomes of patients who underwent blind sac closure of the external auditory canal (EAC) via a modified Rambo approach. Study Design: Retrospective case review. Setting: Tertiary academic referral center. Methods: All patients who underwent EAC closure with a modified Rambo approach between 2015 and 2021 were evaluated. Complication rates, QOL estimations from a validated survey, and subjective cosmetic reports were analyzed. Results: Thirty‐five ears were closed in 31 patients. The most common indication for surgery was related to cochlear implantation and cochlear malformation or cholesteatoma (31.4%). No case involved an immediate complication requiring revision surgery, and 4 ears (11.4%) were suspected of having cholesteatoma within the surgical cavity at a mean 28.6‐month follow‐up. Adults (≥18 years) had significantly higher QOL scores than children in the medical resource subscale of the Chronic Ear Survey (P <.01), and patients undergoing concurrent EAC closure and skull base tumor removal scored higher than others (P =.04). Females reported higher cosmetic scores than males (P =.04). QOL and cosmetic scores compared favorably to previously published data involving the management of otologic disease. Conclusions: Ear canal closure can be a useful technique for select adult and pediatric patients. Patient and surgeon concerns regarding QOL and cosmesis in ear canal closure should be explored prior to employing this surgical technique, though the present data suggest that the modified Rambo approach to closure is generally associated with reasonable outcomes in both areas. [ABSTRACT FROM AUTHOR]

Published
2023
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48. Racial and Socioeconomic Disparities in Patients With Meningioma: A Retrospective Cohort Study

Author

Jackson, Hudin N., primary, Hadley, Caroline C., additional, Khan, A. Basit, additional, Gadot, Ron, additional, Bayley, James C., additional, Shetty, Arya, additional, Mandel, Jacob, additional, Jalali, Ali, additional, Gallagher, K. Kelly, additional, Sweeney, Alex D., additional, Harmanci, Arif O., additional, Harmanci, Akdes S., additional, Klisch, Tiemo, additional, Gopinath, Shankar P., additional, Rao, Ganesh, additional, Yoshor, Daniel, additional, and Patel, Akash J., additional

Published
2021
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