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15 results on '"Swarovski, Michelle S."'

1. TREM1 disrupts myeloid bioenergetics and cognitive function in aging and Alzheimer disease mouse models

Author

Wilson, Edward N., Wang, Congcong, Swarovski, Michelle S., Zera, Kristy A., Ennerfelt, Hannah E., Wang, Qian, Chaney, Aisling, Gauba, Esha, Ramos Benitez, Javier A., Le Guen, Yann, Minhas, Paras S., Panchal, Maharshi, Tan, Yuting J., Blacher, Eran, A. Iweka, Chinyere, Cropper, Haley, Jain, Poorva, Liu, Qingkun, Mehta, Swapnil S., Zuckerman, Abigail J., Xin, Matthew, Umans, Jacob, Huang, Jolie, Durairaj, Aarooran S., Serrano, Geidy E., Beach, Thomas G., Greicius, Michael D., James, Michelle L., Buckwalter, Marion S., McReynolds, Melanie R., Rabinowitz, Joshua D., and Andreasson, Katrin I.

Published
2024
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2. Performance of a fully-automated Lumipulse plasma phospho-tau181 assay for Alzheimer’s disease

Author

Wilson, Edward N., Young, Christina B., Ramos Benitez, Javier, Swarovski, Michelle S., Feinstein, Igor, Vandijck, Manu, Le Guen, Yann, Kasireddy, Nandita M., Shahid, Marian, Corso, Nicole K., Wang, Qian, Kennedy, Gabriel, Trelle, Alexandra N., Lind, Betty, Channappa, Divya, Belnap, Malia, Ramirez, Veronica, Skylar-Scott, Irina, Younes, Kyan, Yutsis, Maya V., Le Bastard, Nathalie, Quinn, Joseph F., van Dyck, Christopher H., Nairn, Angus, Fredericks, Carolyn A., Tian, Lu, Kerchner, Geoffrey A., Montine, Thomas J., Sha, Sharon J., Davidzon, Guido, Henderson, Victor W., Longo, Frank M., Greicius, Michael D., Wagner, Anthony D., Wyss-Coray, Tony, Poston, Kathleen L., Mormino, Elizabeth C., and Andreasson, Katrin I.

Published
2022
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3. Association of CSF Biomarkers with Hippocampal-dependent Memory in Preclinical Alzheimer Disease

Author

Trelle, Alexandra N, Carr, Valerie A, Wilson, Edward N, Swarovski, Michelle S, Hunt, Madison P, Toueg, Tyler N, Tran, Tammy T, Channappa, Divya, Corso, Nicole K, Thieu, Monica K, Jayakumar, Manasi, Nadiadwala, Ayesha, Guo, Wanjia, Tanner, Natalie J, Bernstein, Jeffrey D, Litovsky, Celia P, Guerin, Scott A, Khazenzon, Anna M, Harrison, Marc B, Rutt, Brian K, Deutsch, Gayle K, Chin, Frederick T, Davidzon, Guido A, Hall, Jacob N, Sha, Sharon J, Fredericks, Carolyn A, Andreasson, Katrin I, Kerchner, Geoffrey A, Wagner, Anthony D, and Mormino, Elizabeth C

Published
2021
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5. Diagnostic and Prognostic Performance of the Modified Lumipulse pTau 181 Assay in Plasma for Alzheimer’s Disease

Author

Wilson, Edward N., primary, Young, Christina B, additional, Benitez, Javier A. Ramos, additional, Vandijck, Manu, additional, Swarovski, Michelle S., additional, Shahid, Marian, additional, Corso, Nicole, additional, Kennedy, Gabriel, additional, Trelle, Alexandra N, additional, Channappa, Divya, additional, Belnap, Malia, additional, Lind, Betty, additional, Bastard, Nathalie Le, additional, Quinn, Joseph F, additional, Nairn, Angus C, additional, Kerchner, Geoffrey A., additional, Sha, Sharon, additional, Wagner, Anthony D, additional, Henderson, Victor, additional, Longo, Frank M., additional, Wyss‐Coray, Tony, additional, Poston, Kathleen L, additional, Mormino, Elizabeth C., additional, and Andreasson, Katrin I., additional

Published
2022
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6. CSF Biomarkers of Amyloid and Tau Pathologies in Participants Enrolled in the Stanford Alzheimer’s Disease Research Center

Author

Ramos Benitez, Javier A., primary, Wilson, Edward N., additional, Swarovski, Michelle S., additional, Shahid, Marian, additional, Corso, Nicole, additional, Channappa, Divya, additional, Belnap, Malia, additional, Tian, Lu, additional, Kerchner, Geoffrey A., additional, Sha, Sharon, additional, Henderson, Victor, additional, Longo, Frank M., additional, Wyss‐Coray, Tony, additional, Poston, Kathleen L, additional, Mormino, Elizabeth C., additional, and Andreasson, Katrin I., additional

Published
2022
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7. Additional file 5 of Performance of a fully-automated Lumipulse plasma phospho-tau181 assay for Alzheimer’s disease

Author

Wilson, Edward N., Young, Christina B., Ramos Benitez, Javier, Swarovski, Michelle S., Feinstein, Igor, Vandijck, Manu, Le Guen, Yann, Kasireddy, Nandita M., Shahid, Marian, Corso, Nicole K., Wang, Qian, Kennedy, Gabriel, Trelle, Alexandra N., Lind, Betty, Channappa, Divya, Belnap, Malia, Ramirez, Veronica, Skylar-Scott, Irina, Younes, Kyan, Yutsis, Maya V., Le Bastard, Nathalie, Quinn, Joseph F., van Dyck, Christopher H., Nairn, Angus, Fredericks, Carolyn A., Tian, Lu, Kerchner, Geoffrey A., Montine, Thomas J., Sha, Sharon J., Davidzon, Guido, Henderson, Victor W., Longo, Frank M., Greicius, Michael D., Wagner, Anthony D., Wyss-Coray, Tony, Poston, Kathleen L., Mormino, Elizabeth C., and Andreasson, Katrin I.

Abstract

Additional file 5: Table S5. Betas (standard errors) and p values for models examining plasma p-tau181 and longitudinal change in global cognition and function.

Published
2022
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8. Additional file 2 of Performance of a fully-automated Lumipulse plasma phospho-tau181 assay for Alzheimer’s disease

Author

Wilson, Edward N., Young, Christina B., Ramos Benitez, Javier, Swarovski, Michelle S., Feinstein, Igor, Vandijck, Manu, Le Guen, Yann, Kasireddy, Nandita M., Shahid, Marian, Corso, Nicole K., Wang, Qian, Kennedy, Gabriel, Trelle, Alexandra N., Lind, Betty, Channappa, Divya, Belnap, Malia, Ramirez, Veronica, Skylar-Scott, Irina, Younes, Kyan, Yutsis, Maya V., Le Bastard, Nathalie, Quinn, Joseph F., van Dyck, Christopher H., Nairn, Angus, Fredericks, Carolyn A., Tian, Lu, Kerchner, Geoffrey A., Montine, Thomas J., Sha, Sharon J., Davidzon, Guido, Henderson, Victor W., Longo, Frank M., Greicius, Michael D., Wagner, Anthony D., Wyss-Coray, Tony, Poston, Kathleen L., Mormino, Elizabeth C., and Andreasson, Katrin I.

Abstract

Additional file 2: Table S2. Characteristics of Participants Stratified by Diagnosis and AD CSF Biomarkers.

Published
2022
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9. Additional file 4 of Performance of a fully-automated Lumipulse plasma phospho-tau181 assay for Alzheimer’s disease

Author

Wilson, Edward N., Young, Christina B., Ramos Benitez, Javier, Swarovski, Michelle S., Feinstein, Igor, Vandijck, Manu, Le Guen, Yann, Kasireddy, Nandita M., Shahid, Marian, Corso, Nicole K., Wang, Qian, Kennedy, Gabriel, Trelle, Alexandra N., Lind, Betty, Channappa, Divya, Belnap, Malia, Ramirez, Veronica, Skylar-Scott, Irina, Younes, Kyan, Yutsis, Maya V., Le Bastard, Nathalie, Quinn, Joseph F., van Dyck, Christopher H., Nairn, Angus, Fredericks, Carolyn A., Tian, Lu, Kerchner, Geoffrey A., Montine, Thomas J., Sha, Sharon J., Davidzon, Guido, Henderson, Victor W., Longo, Frank M., Greicius, Michael D., Wagner, Anthony D., Wyss-Coray, Tony, Poston, Kathleen L., Mormino, Elizabeth C., and Andreasson, Katrin I.

Abstract

Additional file 4: Table S4. Betas (standard errors) and p values for models examining plasma p-tau181 and cross-sectional cognition and function.

Published
2022
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10. Additional file 3 of Performance of a fully-automated Lumipulse plasma phospho-tau181 assay for Alzheimer’s disease

Author

Wilson, Edward N., Young, Christina B., Ramos Benitez, Javier, Swarovski, Michelle S., Feinstein, Igor, Vandijck, Manu, Le Guen, Yann, Kasireddy, Nandita M., Shahid, Marian, Corso, Nicole K., Wang, Qian, Kennedy, Gabriel, Trelle, Alexandra N., Lind, Betty, Channappa, Divya, Belnap, Malia, Ramirez, Veronica, Skylar-Scott, Irina, Younes, Kyan, Yutsis, Maya V., Le Bastard, Nathalie, Quinn, Joseph F., van Dyck, Christopher H., Nairn, Angus, Fredericks, Carolyn A., Tian, Lu, Kerchner, Geoffrey A., Montine, Thomas J., Sha, Sharon J., Davidzon, Guido, Henderson, Victor W., Longo, Frank M., Greicius, Michael D., Wagner, Anthony D., Wyss-Coray, Tony, Poston, Kathleen L., Mormino, Elizabeth C., and Andreasson, Katrin I.

Abstract

Additional file 3: Table S3. Betas (standard errors) and p values within and between clinical groups for models examining longitudinal change in plasma p-tau181.

Published
2022
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11. Additional file 1 of Performance of a fully-automated Lumipulse plasma phospho-tau181 assay for Alzheimer’s disease

Author

Wilson, Edward N., Young, Christina B., Ramos Benitez, Javier, Swarovski, Michelle S., Feinstein, Igor, Vandijck, Manu, Le Guen, Yann, Kasireddy, Nandita M., Shahid, Marian, Corso, Nicole K., Wang, Qian, Kennedy, Gabriel, Trelle, Alexandra N., Lind, Betty, Channappa, Divya, Belnap, Malia, Ramirez, Veronica, Skylar-Scott, Irina, Younes, Kyan, Yutsis, Maya V., Le Bastard, Nathalie, Quinn, Joseph F., van Dyck, Christopher H., Nairn, Angus, Fredericks, Carolyn A., Tian, Lu, Kerchner, Geoffrey A., Montine, Thomas J., Sha, Sharon J., Davidzon, Guido, Henderson, Victor W., Longo, Frank M., Greicius, Michael D., Wagner, Anthony D., Wyss-Coray, Tony, Poston, Kathleen L., Mormino, Elizabeth C., and Andreasson, Katrin I.

Abstract

Additional file 1: Table S1. Characteristics of Participants Stratified by Diagnosis and APOE Genotype.

Published
2022
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13. Soluble TREM2 is elevated in Parkinson’s disease subgroups with increased CSF tau

Author

Wilson, Edward N, primary, Swarovski, Michelle S, primary, Linortner, Patricia, primary, Shahid, Marian, primary, Zuckerman, Abigail J, primary, Wang, Qian, primary, Channappa, Divya, primary, Minhas, Paras S, primary, Mhatre, Siddhita D, primary, Plowey, Edward D, primary, Quinn, Joseph F, primary, Zabetian, Cyrus P, primary, Tian, Lu, primary, Longo, Frank M, primary, Cholerton, Brenna, primary, Montine, Thomas J, primary, Poston, Kathleen L, primary, and Andreasson, Katrin I, primary

Published
2020
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14. CSF sTREM2 correlates with CSF tau in advancing Parkinson’s disease

Author

Wilson, Edward N., primary, Swarovski, Michelle S., additional, Linortner, Patricia, additional, Shahid, Marian, additional, Zuckerman, Abigail J., additional, Wang, Qian, additional, Channappa, Divya, additional, Minhas, Paras S., additional, Mhatre, Siddhita D., additional, Plowey, Edward D., additional, Quinn, Joseph F., additional, Zabetian, Cyrus P., additional, Tian, Lu, additional, Longo, Frank M., additional, Cholerton, Brenna, additional, Montine, Thomas J., additional, Poston, Kathleen L., additional, and Andreasson, Katrin I., additional

Published
2019
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15. Plasma Aβ 42 /Aβ 40 is sensitive to early cerebral amyloid accumulation and predicts risk of cognitive decline across the Alzheimer's disease spectrum.

Author

Trelle AN, Young CB, Vossler H, Ramos Benitez J, Cody KA, Mendiola JH, Swarovski MS, Guen YL, Feinstein I, Butler RR 3rd, Channappa D, Romero A, Park J, Shahid-Besanti M, Corso NK, Chau K, Smith AN, Skylar-Scott I, Yutsis MV, Fredericks CA, Tian L, Younes K, Kerchner GA, Deutsch GK, Davidzon GA, Sha SJ, Henderson VW, Longo FM, Greicius MD, Wyss-Coray T, Andreasson KI, Poston KL, Wagner AD, Mormino EC, and Wilson EN

Abstract

Introduction: The availability of amyloid beta (Aβ) targeting therapies for Alzheimer's disease (AD) is increasing the demand for scalable biomarkers that are sensitive to early cerebral Aβ accumulation., Methods: We evaluated fully-automated Lumipulse plasma Aβ 42 /Aβ 40 immunoassays for detecting cerebral Aβ in 457 clinically unimpaired (CU) and clinically impaired (CI) Stanford Alzheimer's Disease Research Center (Stanford ADRC) participants and 186 CU in the Stanford Aging and Memory Study (SAMS). Longitudinal change in ADRC plasma Aβ 42 /Aβ 40 and cognition and cross-sectional associations with SAMS memory and tau positron emission tomography (PET) were examined., Results: Plasma Aβ 42 /Aβ 40 exhibited high performance in detecting amyloid positivity defined by PET (area under the curve [AUC]: 0.885, 95% confidence interval [CI]: 0.816-0.955). Once abnomal, plasma Aβ 42 /Aβ 40 remained low and predicted cognitive decline in both CU and CI individuals. Among SAMS CU, plasma Aβ 42 /Aβ 40 was associated with poorer hippocampal-dependent memory and elevated tau accumulation., Discussion: Lumipulse plasma Aβ 42 /Aβ 40 is a scalable assay for detection of cerebral Aβ and prediction of risk for cognitive decline across the AD continuum., Highlights: Lumipulse plasma amyloid beta (Aβ) 42 /Aβ 40 exhibited high accuracy in detecting amyloid positivity. Plasma amyloid-positive (Aβ+) individuals exhibited stability of Aβ 42 /Aβ 40 over time. Plasma Aβ 42 /Aβ 40 predicted future cognitive decline across the Alzheimer's disease (AD) spectrum. Plasma Aβ 42 /Aβ 40 was sensitive to memory and tau burden in clinically unimpaired older adults., (© 2024 The Author(s). Alzheimer's & Dementia published by Wiley Periodicals LLC on behalf of Alzheimer's Association.)

Published
2024
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