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Intrigue progression of hypertensive encephalopathy (HE) in older patients is that the development of cognitive impairment and high blood pressure underestimated, aslo exist without clinical manifestations. In recent decades convincing proved that the basis for the development of various diseases is cerebral dysfunction systems regulating brain blood flow, including--autoregulation system, which largely affects the blood supply to the brain. This explains the fact that patients with chronic brain ischemia cerebral hemodynamic status largely depends on the condition and stability of the regulatory mechanisms of systemic and cerebral hemodynamics, particularly of systemic blood pressure, regional cerebral blood supply, normalization which, in the early stages of development disorders, prevents of serious complications. In this paper the theoretical generalization and new solution of scientific and practical problems of hypertension influence on the formation of chronic cerebral ischemia in elderly patients on a background of hypertension--specified risk factors and especially the formation of a comprehensive study on the basis of clinical and neurological data, tool sand methods for neuroimaging research developed and improved methods of diagnosis. Found that in elderly patients with HE and HBP observed significant (P < 0.05) increase in the thickness of the intima-media complex was significantly higher (dextra--1.12 ± 0.03 and sinistra--1.11 ± 0.03), than middle-aged patients with hypertension at HE, which constitutes a violation of the elastic properties of the vascular wall. Established correlation data radionuclide study ultrasonic duplex scanning of vessels of the head and neck. A negative correlation of intima-media and severity of lesions according to hypoperfusion of computer tomography single photon emission (r = -0.49; P < 0.05); confirming the progression of HE in elderly patients needs improvement and treatment.

The aim of the research was to study risk factors of development of re-ischemic stroke. Clinical and laboratory investigation of 46 patients with ischemic stroke was conducted. In group I the asymptomatic form of an ischemic insult was revealed in 22 (47,8%) of patients, of which 13 (59%) of patients one transferred insult, and at the others of 9 (41%) - more than one insult is revealed. In group with the diagnosed repeated asymptomatic insult, an arterial hypertensia came to light at 24 (100%) of patients, reliably above (p<0,01) the ischemic heart disease 13 (59,0%) and chronic heart condition 18 (81,8%) diagnosed. On МRT at 36,4% of patients with the diagnosed repeated asymptomatic insult the centers are located in the same pool of blood supply of the same hemisphere, as at the first insult, that reliably (р<0,01) correlated with a degree of expressiveness of neurologic deficiency. The obtained given assessments of risk factors of progress of an insult assist early revealing of asymptomatic insults.