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Objective. The aim of this paper is to investigate the influence of nutrition and pattern behaviors on bone health in people with mental health disorders. Methods. A cross-sectional study has been conducted at the Clinic for Psychiatry of the Clinical Center of Kragujevac and at the Department of Neuropsychiatry of the Specialist-Consultative Service of Health Care Center Kragujevac. The survey included 46 patients from the age of 22 to 81, both genders, with schizophrenia as a diagnosis for mental disorders and depression determined by a psychiatrist. Quantitative testing of calcium, magnesium, phosphorus, sodium and potassium has been performed by standard biochemical methods. Vitamin D has been determined by high performance/pressure liquid chromatography i.e. by a liquid chromatography under high pressure. Results. In the whole group of patients tested, 58.7% of patients were physically active and the patients with schizophrenia (p = 0.026) were less physically active. Out of the total number, 67% of patients eat irregularly and this habit is more present in patients with schizophrenia (p = 0.003). In terms of the presence of certain nutrients, fish is more represented in the nutrition of people suffering from depression. Three patients (6.5%) reported osteoporosis in their medical history, one of whom had a spontaneous fracture. In the anamneses (6.5%) of the patients stated that their parents had had spontaneous bone fractures. Low values of 25 (OH) D in the serum were present in both study groups. Conclusion. Unhealthy lifestyles, low level of Vitamin D found in people who have mental health disorders represent risk factors for the reduced bone mass. The results of our research indicate the need for timely identification of potential risk factors and improvement of prevention in order to raise awareness of the importance of healthy lifestyles and behavior modification.

Background: Comorbidities are major predictors of in-hospital mortality in stroke patients. The Charlson comorbidity index (CCI) and the Elikhauser comorbidity index (ECI) are scoring systems for classifying comorbidities. We aimed to compare the performance of the CCI and ECI to predict in-hospital mortality in stroke patients. Methods: We included patients hospitalized for stroke in the Clinical Center of Kragujevac, Serbia for the last 7 years. Hospitalizations caused by stroke, were identified by the International Classification of Diseases-10 (ICD-10) codes I60.0 - I69.9. All patients were divided into two cohorts: Alive cohort (n=3297) and Mortality cohort (n=978). Results: There were significant associations between higher CCIS and increased risk of in-hospital mortality (HR = 1.07, 95% CI = 1.01–1.12) and between higher ECIS and increased risk of in-hospital mortality (HR = 1.04, 95% CI = 0.99–1.09). Almost 2/3 patients (66.9%) had comorbidities included in the CCI score and 1/3 patients (30.2%) had comorbidities included in the ECI score. The statistically significant higher CCI score (t = -3.88, df = 1017.96, P

CONTEXT: Clinical research suggests that vitamin D deficiency correlates with mental illnesses. OBJECTIVE: The aim was to prove that the patients from the psychiatric health care service in Serbia had higher vitamin D deficiency than patients from general practice. DESIGN: The study had a cross-sectional design. METHODS: The study included 47 patients aged 19 – 76 of both sexes with different mental disorders. We performed sample size calculation on available data for vitamin D deficiency in patients in health care facilities compared with the general population. The concentrations of vitamin D in serums were measured by HPLC (high performance/pressure liquid chromatography). RESULTS: The mean value of vitamin D (standard deviation) in the whole group of study subjects was 16.27(10.62) ng/mL; 68.1% of the patients had a deficiency of vitamin D (25(OH)D

Introduction Smoking has been linked to cancer occurrence and survival rates for a long time. However, there is little research into the impacts of smoking on oncological treatments. The aim of the study is to show the impact that smoking can have on the effects of cancer therapy. Methods Epidemiological situation analysis of the malignant diseases based on the data of incidence and mortality and the impact of smoking on the results of treatment. Results At the time of establishing the diagnosis, the incidence of smoking varies from 10 to 95 per cent ( 60% for lung cancer). The previous research indicates that continuing smoking after the establishment of a diagnosis can impact the treatment outcomes and is related to worse prognosis and survival rate. Active smoking can be connected to lower survival rates with advanced non-small cell lung cancer, limited small cell lung cancer, bladder cancer, and upper tract urothelial cancer. The smokers suffering from prostate cancer have a higher risk of death outcomes and worse prognoses after the treatment. The research has shown that there is a link between smoking and slower wound healing in operated patients and that it can also intensify the side-effects of chemotherapy and prolong the responses to radiation. Conclusions It is essential to increase knowledge about the health benefits of quitting smoking in order to advance the results of oncological treatments. Implemented smoking cessation programs need to be adapted to oncology patients.

Background/Aim. Admission diagnosis represents the diagnosis of an illness, injury or condition due to which a patient is referred to hospital to be admitted. Discharge diagnosis represents the main reason of illness or condition due to which a patient is admitted. The aim of this study was to analyze the agreement between admission diagnostic groups and discharge diagnostic groups of patients in the Clinical Center Kragujevac in the period from January 1, 2006 to December 31, 2013 on the basis of the hospitalization report. Methods. From the basic set of reports, 5% of random samples were singled out and they contained 20,422 reports. Out of the given number of reports, 18,173 hospitalization reports were complete and then further analyzed in the paper. Admission diagnostic groups given by the primary care doctor were compared with discharge diagnostic groups filled out by the practicing physician in the hospital ward from which a patient was discharged. The agreement of these two diagnostic groups was an indication of the high-quality performance of the primary care doctor. Agreement analysis was conducted using Cohen?s Kappa statistics. Results. Agreement analysis showed that the values of the Kappa coefficient for the five leading admission diagnostic groups were in the range of ? = 0.61 to ? = 0.94. The values of the Kappa coefficient for the five most common discharge diagnostic groups were in the range of ? = 0.55 to ? = 0.81. Conclusion. Hospitalization report is a reliable individual report on inpatient care, so it could be used in determining the degree of agreement between admission diagnostic groups and discharge diagnostic groups.

To assess the motivation and barrier factors influencing participation of women in opportunistic breast cancer screening in Belgrade, Serbia, and to detect changes in these factors over time.A cross-sectional study has been carried out at the Institute for Oncology and Radiology of Serbia in 2009 and 2016 among women aged 40 to 69 years from Belgrade who came at the Institute for opportunistic breast cancer screening. The demographic characteristics, data regarding breast exams practices, screening motivators and barriers and sources of information on breast cancer were collected by self-administered questionnaire.The questionnaire was completed by 478 women in 2009 and 453 in 2016, with increase in women reporting regular mammograms or at least one previous mammogram (from 30.1% to 58.6%, p=0.000). In 2009, the most frequent motivating factors were health maintenance (36%), friend's advice, TV, cancer in the family or fear of breast cancer; in 2016, advice from gynecologist (significant increase from 10.9% to 37.7%, p=0.000), health maintenance, family cancer and fear of cancer. The most frequent reasons for not going to exams regularly were absence of breast problems, crowded doctor's offices and no family breast cancer.These findings provide information on motivation and barrier factors that may influence women's decision to participate in opportunistic breast cancer screening. Those factors have changed over time and the role of physicians has increased significantly. Further exploration of motivating and barrier factors and the extent of their association with actual women's behavior would be helpful for the development of interventions to improve organized and opportunistic screening participation.

Introduction It has been proven that tobacco is the most dangerous single risk factor for development of many chronic diseases, cancer or early death. Tobacco smoke has more than 7000 chemicals, at least 250 are known to be harmful and more than 50 are known to cause cancer. Although quit smoking medications – substitution therapy has been approved and officially acknowledged as well as programs for stop smoking, the smoking rate is still very high. More than 1/6 of world population (1.1 billion) are smokers. The aim of this work is to present the importance of carrying out stop smoking programs for patients dealing with cancer. Methods The analysis of epidemiological situation of malignant disease is based on information of incidence and mortality as well as on smoking impacts. Results Researches show that larger part of oncological patients recognizes smoking as harmless and determination of diagnosis motivates these patients to stop smoking. Estimations show that 38% to 65% of cancer patients stop smoking in the first year after confirming diagnosis. Quitting smoking during oncological treatment is related to: better treatment response, reduced risk of complications, better quality of life and reduced risk of disease progression. Quitting smoking among oncological patients will affect long-term health as well by reducing risks of development of other diseases (heart attack, stroke). Conclusions All patients disregarding the stage of disease during oncological treatment may benefit from smoking cessation and have a right to quitting smoking treatment. Health care workers may improve motivation and influence quitting by providing help, giving advice and prescribing medications.

The aim of this study was to determine the frequency of ocular symptoms and compare the demographic and clinical characteristics in AR patients depending on sensitisation to various types of aeroallergens. Allergic rhinitis is defined as an IgE-mediated inflammation of the lining of the nose that is characterized by nasal symptoms, including nasal congestion, sneezing, itching of nose and runny nose. Patients suffering from allergic rhinitis frequently experience ocular symptoms such as ocular redness, eye itching and tears. The frequency of ocular symptoms in our study population was 27,6%. No statistical significance was found in the mean ages of the patients who did or did not experience ocular symptoms p>0,05 (p=0,243). Our results indicated that there were no statistical differences (p>0,05) among the groups of allergic rhinitis patients based on experiencing nasal symptoms according to the types of aeroallergens. Our results indicated that there were significant experiences of ocular symptoms in patients who were sensitised to outdoor aeroallergens (p Ocular symptoms are more common in patients who are sensitised to outdoor aeroallergens.

Objective. The aim of this study was to evaluate different aspects of job satisfaction among employees as well as to evaluate the overall job satisfaction in health care institutions of the primary health care level in Sumadija district. Methods. Employee satisfaction survey was conducted in 10 primary health facilities in Sumadija district. We conducted a one-day survey of 1273 employees, using a uniform, anonymous questionnaire developed by the Ministry of Health of the Republic of Serbia within the program of improvement of the quality of health care facilities. Results. The data we obtained show that a little less than a half of the employees in healthcare institutions of the Republic of Serbia were satisfied with the work they performed. The results of logistic regression showed that, among the factors examined, the following had a statistically significant impact on the assessment of job satisfaction: adequacy of work equipment, possibility of professional development, support by superiors, comparison of satisfaction of 5 years ago and now. Conclusion. Job-related experience and satisfaction of the employees indicate the need for placement of employee satisfaction as a priority in the process of improving the quality of the health care system.

The aim of this study was to develop a new material which has high hydrogen storage capacity and hydrogen absorption/desorption rate. This material, which is based on cobalt powder onto which palladium was chemically deposited can be used in environmentally friendly energy generation processes, thus ensuring preventive protection of human health. Hydrogen absorption was investigated using differential scanning calorimetry (DSC) and by measuring hydrogen pressure under isothermal and non-isothermal conditions in a chamber containing either pure cobalt powder either cobalt powder onto which palladium was chemically deposited (Co-0.003 Pd). The mechanism of hydrogen absorption has been described. It was noticed that palladium catalyses hydrogen absorption by dissociating the adsorbed H2 molecules into H atoms more rapidly on its own atoms than on cobalt ones. The catalysis of dissociation of H2 molecules enabled hydrogen absorption into Co-0.003 Pd powder to occur at lower temperatures. The results of this study enable integration of technological and public health investigation in order to ensure preventive protection of human health through enviromental protection.

Background and context: The Institute of Oncology and Radiology of Serbia (IORS), supported by the Ministry of Health, launched the project Knowledge Against Cancer in 2015, whose aim was to prepare educational material for cancer patients. Thirteen brochures were presented on WCC in Paris in 2016. The IORS conducted a survey among oncology patients in January 2017 for them to evaluate the distributed brochures and suggest the topics for new educational material. Aim: This paper aims at evaluation of brochures for cancer patients which were created during the project and its primary goal is to define new topics for future educational material. Strategy/Tactics: The study includes 348 respondents (92% women, 8% men) with average age of 54.77 ± 13.26 and predominantly highly educated (45.4%). 90% of the respondents has evaluated this kind of educational material as significant. The study has also examined the choice and relevance of topics and the quantity and usage potential of new data. The analysis has shown that most patients are interested in including psychological aspects of cancer treatment as a new topic (76%) and in including topics concerning healthy lifestyles (69%). As the majority of the respondents are women, the significant interest has been shown for topics concerning lifedem and tumor radiation of female genital organs (over 85% of female respondents). Based on the results obtained through survey and consultations and interviews with patient support group and patients associations the educational brochures were created. Program/Policy process: In 2017, nine new topics were prepared by multidisciplinary teams from IORS: Brochure: psychological support for oncology patients, the manual for family and friends, the manuals for patients on radiation of tumors on female genital organs, for head and neck tumors, lymphoedema - prevention and treatment, treatment of thyroid gland cancer with radioactive iodine, tumor markers and laboratory diagnostic, prevention of malign illnesses and quitting smoking. Outcomes: Brochures are currently available both in paper and on the Web site free of charge. The design of mobile phone application is planned for the future. The educational material is not only presented and distributed to cancer families and the public but also to health professionals and medical workers. What was learned: The research has shown that this educational material is very important for cancer patients and that with adequate information and data such patients can improve life quality predominantly through the reduction of fears and anxiety, development of coping mechanisms to deal with the cancer diagnosis and treatment and encouraging them to take active part in cancer treatment.

An explicit integration algorithm using a texture-based plastic potential and isotropic hardening has been developed and implemented into a commercial explicit finite-element software program through a user material subroutine (VUMAT in ABAQUS/Explicit). Simulations of cup drawing of an IF-steel are presented and compared to both experimental data and calculation results obtained with a previously developed fully implicit approach (UMAT in ABAQUS/Standard). The explicit formulation has the advantage of being more stable, but local sheet thickness variations cannot be reproduced with the same accuracy.