1. A-199 Executive Functioning and Memory Outcomes of Children with Low-Grade Gliomas
- Author
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Fong G, Vitale S, Ingerski L, and Sutcliff J
- Subjects
Psychiatry and Mental health ,Clinical Psychology ,Neuropsychology and Physiological Psychology ,General Medicine - Abstract
Objective The current study used standardized performance-based measures to examine specific executive functioning and memory outcomes of children with low-grade gliomas (LGGs). Historically, this population has excellent survival and does not receive extensive neuropsychological follow-up; however, recent literature suggested the presence of late-effects following treatment completion, specifically executive functioning and memory difficulties. Additional research is needed to identify what late-effects children with LGGs experience and what degree of neuropsychological follow-up is required for optimal survivorship care. Method A systematic retrospective chart review was conducted to evaluate outcomes. Inclusion criteria required that youth were previously diagnosed with a pediatric LGG, followed in a single pediatric cancer center, and completed outpatient neuropsychological testing. Comprehensive neuropsychological testing assessed: executive (Conners’ Continuous Performance Test, Behavior Rating Inventory of Executive Function) and memory functioning (California Verbal Learning Test, Wechsler Memory Scale). Results Preliminary data from 10 participants who completed neuropsychological testing at 12.0 (SD = 4.1) years of age has been analyzed. Seventy additional participants will be included in analyses. All participants underwent surgical resection and 40% completed additional chemotherapy. Descriptive statistics identified those youth experiencing deficits (< 1SD) using standard scores in executive and memory functioning domains. In summary, 66% received ≥3 atypical scores on a measure of attention, and 80% experienced memory deficits. In total, 50% of participants were diagnosed with Mild Neurocognitive Disorder following testing. Conclusions This pilot study provided evidence of executive functioning and memory deficits experienced by children previously treated for LGG. Standardized neuropsychological assessment may enhance survivorship care for youth previously diagnosed with an LGG.
- Published
- 2020
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