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To assess mid-/long-term postoperative quality of life (QOL) of esophageal atresia (EA) patients.Modified gastrointestinal quality-of-life index surveys were administered to postoperative EA patients who were at least 7 years old at evaluation to assess three topics about general lifestyle (GL), five topics about EA, and four topics about mental health (MH). For MH, caregivers were also interviewed, but separately. Subjects were divided according to age: children (7-12 years old), teenagers (13-19), and adults (20 and over) and compared according to Foker or Kimura elongation (FK) or bougienage stretching (BS).There were 22 patients evaluated. Responses for GL, EA, and MH did not differ significantly between age groups, but MH responses by caregivers for subjects who were children or teenagers scored significantly lower than responses they made themselves. For primary esophageal elongation technique (PET), age at esophagoesophagostomy was significantly higher in FK. Despite FK scoring 15.1 versus 12.4 for BS during EA evaluation, this difference was not statistically significant.Changes in QOL responses according to age were unremarkable. However, discrepancies in MH indicate that subjects felt better than their caregivers thought. PET did not appear to influence QOL.

To assess mid-/long-term quality of life (QOL) of total colonic aganglionosis (TCA) patients.Modified pre-existing QOL assessment tools for general lifestyle (GL), bowel function (BF), and mental health (MH) were administered to postoperative TCA patients from five institutions, who were at least 7 years old to compare Duhamel (with pouch) and Swenson/Soave (without pouch) techniques between children (Ch 7-12 years old), teenagers (Tn 13-19), and adults (Ad 20 and over). For MH, caregivers were also interviewed, but separately. Maximum scores were 12 for GL/MH and 18 for BF.There were 32 subjects. GL and BF scores increased significantly from Ch (GL 4.8 ± 2.5, BF: 11.3 ± 4.6) to Tn (GL 7.8 ± 2.6, BF 16.2 ± 3.0); scores for MH did not change significantly. Mean caregiver MH scores were significantly lower than mean subject MH scores for all age groups (subject scores: 10.1, 10.7, 10.7 versus caregiver scores: 6.8, 7.8, 8.1 for Ch, Tn, Ad, respectively). PT technique/presence of a pouch did not influence the incidence of enterocolitis or QOL scores.MH responses showed subjects felt better than caregivers believed. This discrepancy could cause conflict despite steadily improving GL/BF. QOL was unaffected by PT technique/presence of a pouch.

This study analysed the electronic structures of dislocations in 9Cr steel using a spherical aberration-corrected scanning transmission electron microscope equipped with a monochromated electron en...

Semi-natural grasslands on steep slopes often show high plant species diversity, probably due to the water and nutrient limitations that prevent the growth of dominant species and decrease interspecific competition. Traditional management practices like mowing help to maintain species diversity, whereas land abandonment reduces diversity by increasing competition from dominant species and reducing seedling recruitment. The reintroduction of management can reverse species diversity declines, but suitable grassland restoration programs are scarce in Japan. To study the effect of short-term abandonment on seedling ecology, we monitored the vegetation of a Susogari grassland that had been abandoned for 3 years; the grassland occupies a steep slope (ca. 50°) on a hillside above paddy fields. We monitored the vegetation before abandonment, in the 3rd year of abandonment, and in the 1st and 2nd years after restoration of mowing management. Emergence and survival of seedlings was monitored for 18 months after reintroduction of management. We monitored 1183 seedlings of grassland species and non-target annuals in ten 1-m2 plots. After mowing was reintroduced, most grassland species reappeared or increased in the first and second years. Few seedlings of perennial plants and no seedlings of annuals flowered. An exotic species, Solidago altissima, had a lower survival rate (10%) than grassland species (>30%), and all but two grassland species survived over the 18-month period. Our findings suggest that a steep slope acts as a strong filter that inhibits the establishment of non-target species while enhancing persistence of target grassland species.

Herbaceous vegetation on riverdikes plays an important role in preventing soil erosion, which, otherwise, may lead to the collapse of riverdikes and consequently, severe flooding. It is crucial for managers to keep suitable vegetation conditions, which include native grass species such as Imperata cylindrica, and to secure visibility of riverdikes for inspection. If managers can efficiently find where suitable grass and unsuitable forb species grow on vast riverdikes, it would help in vegetation management on riverdikes. Classification and quantification of herbaceous vegetation is a challenging task. It requires spatial resolution and accuracy high enough to recognize small, complex-shaped vegetation on riverdikes. Recent developments in unmanned aerial vehicle (UAV) technology combined with light detection and ranging (LiDAR) may offer the solution, since it can provide highly accurate, high-spatial resolution, and denser data than conventional systems. This paper aims to develop a model to classify grass and forb species using UAV LiDAR data alone. A combination of UAV LiDAR-based structural indices, V-bottom (presence of vegetation up to 50 cm from the ground) and V-middle (presence of vegetation 50–100 cm from the ground), was tested and validated in 94 plots owing to its ability to classify grass and forb species on riverdikes. The proposed method successfully classified the “upright” grass species and “falling” grass species / forb species with an accuracy of approximately 83%. Managers can efficiently prioritize the inspection areas on the riverdikes by using this method. The method is versatile and adjustable in other grassland environments.

Background: Fibroblast growth factors (FGF) expressed in the genital tubercle, especially FGF8 and FGF10, may be implicated in the morphogenesis of external genitalia. We investigated the expression of FGF8 and FGF10 in hypospadias prepuce to confirm any correlation.Methods: Hypospadias was classified according to the location of the external meatus as coronal/subcoronal (mild; n=7), midshaft (moderate; n=6), penoscrotal (severe; n=3). Prepuce tissue specimens obtained intraoperatively from hypospadias patients (H; n=16), phimosis patients (P; n=8) between 2010 and 2016 were examined immunohistochemically. Quantification of immunostaining was performed using imageJ®. The protein expression of FGF10 in each group was examined by Western blot analysis.Results: Mean ages at surgery were 3.9 and 4.5 years for H and P, respectively. Both FGF8 and FGF10 were expressed in the upper dermis, especially the papillary layer. FGF8 was similar, but FGF10 was down-regulated in H in proportion to severity (P: 13.08% versus mild H: 7.28%, moderate H: 5.01%, severe H: 1.38%). The FGF10 protein amount results showed FGF10 was down-regulated in H (phimosis 0.91, mild 0.99, moderate 0.65, severe 0.48).Conclusion: The significant down-regulation of FGF10 identified may contribute to further understanding the etiology of hypospadias and may have some possible applications for treating hypospadias.

Although pediatric tracheostomy has been a widely performed, life-saving procedure, its long-term outcomes have remained unclear. This study aimed to review outcomes after tracheostomy at a Japanese tertiary hospital and clarify candidates for and timing of decannulation.Hospital records of critically ill children who underwent tracheostomy from 2001 to 2014 were retrospectively reviewed, subsequently analyzing outcomes according to demographics, complications, and decannulation. After excluding those who were lost to follow-up or had irreversible neuromuscular impairment, the remaining patients were divided into the decannulation (D group) and nondecannulation (ND group) groups and compared.In total, 184 patients who underwent tracheostomy were analyzed (median age at operation: 0.5 y). The major indication for tracheostomy was irreversible neuromuscular impairment (46%). Surgery-related and overall mortality rates were 1% and 25%, respectively, while the successful decannulation rate was 21%. No significant difference in surgical indications or comorbidities was observed between the D (n = 39) and ND (n = 50) groups, except for infection (7 in D group versus 0 in ND group; P = 0.002) and chromosome-gene disorder (15% versus 34%; P = 0.04). The ND group had a significantly higher mortality rate than the D group (46% versus 3%; P 0.0001). The median time to decannulation was 3.6 years, while that for infection was 0.7 y.Patients who underwent tracheostomy at our institution due to temporary infections achieved more successful and earlier decannulation compared to other indications. Chromosome-gene disorder as a comorbidity can negatively affect decannulation.

Paddy fields are generally submerged during the growing season and drained in the fallow season, and occasionally stimulating the air-drying effect and drying-rewetting effect on soil nitrogen (N) mineralization and soil carbon (C) decomposition. It is important to understand how these two effects take place in Andosol field under organic farming. To elucidate these effects, we incubated fresh, air-dried, and dried-rewetted paddy soil anaerobically under flooded condition. Soils were from the fields subjected to organic rice farming (ORF) for 4���5 years (4ORF), 8���9 years (8ORF), and 12 years (12ORF) with only rice residues and fallow weeds as organic matter applied, and cnventional rice farming (CRF). Soil samples were collected from plow layer of 0���15 cm depth after the rice harvest. The results showed that air-dried and dried-rewetted treatments could significantly increase N mineralization potential in 8ORF and 12ORF. The air-drying effects were not significantly changed in 4ORF, but significantly increased in 8ORF and 12ORF as compared to CRF. The drying-rewetting effects of C decomposition potentials were highest in 12ORF significantly. The N mineralization potential of air-drying effect showed no significant difference compared to drying-rewetting effect on conventional and organic rice farming. The ratio of C decomposition to N mineralization after 8 weeks incubation was higher in fresh soil (at 7.26���8.61) than those in air-dried (at 4.09���4.35) and dried-rewetted (at 3.94���4.26) soils. These indicated that the easily decomposable soil organic matter under the anaerobic flooded condition from fresh soil was changed by air-drying and drying-rewetting treatments. The slow increase of N mineralization and C decomposition with years of organic farming suggest the slow increase of fallow weed, the biomass of which gradually increase with years. The specific behavior of 12ORF soil suggest the transition of soil condition from a transitional state to an established state.

After direct discharges of highly contaminated water of the Fukushima Daiichi Nuclear Power Plant (1 F) from April to May 2011, Kanda suggested that relatively small amounts of run-off of radionucl...

This study aimed at understanding whether and how long-term organic rice farming affects soil carbon (C) and nitrogen (N) stocks and their mineralization potentials in submerged rice paddies in Toc...

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Imperata cylindrica is an important component of grasslands in several Asian countries. Its vigorous rhizome elongation enables the plant to quickly cover bare ground, making it a candidate for revegetation projects. In these projects, initial and subsequent management practices often differ. Initial management strategies are important for encouraging rapid cover by the target species. We tested the effects of initial hand weeding on I. cylindrica cover and weed growth over 2 years. Two types of soil (A and B) were scattered on a recently constructed river embankment at a depth of 10 cm. Both soils A and B are nutrient-poor and high (> 7.0) pH. Plots were hand-weeded once or twice a year (W1 and W2 treatments, respectively), or mowed but not weeded (M treatment) with four replications. Plug plants of I. cylindrica were introduced. I. cylindrica became dominant in soil A with the W2 treatment, with 50% cover in year 2. Conversely, I. cylindrica failed to establish in soil B regardless of treatment, due to dominance of the weed Sorghum halepense. Soil B included creeping rhizomes of S. halepense, and vigorous growth from rhizomes is likely a major reason for its predominance. S. halepense seedlings germinated in both soils, but were successfully eradicated when weeded at less than 1 month of age. Thus, for successful revegetation, land managers should use soil that does not contain creeping rhizomes of S. halepense. If rhizomes are not present, hand weeding twice a year for 2 years is sufficient for establishment of I. cylindrica.