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2. The MothersBabies Study, an Australian Prospective Cohort Study Analyzing the Microbiome in the Preconception and Perinatal Period to Determine Risk of Adverse Pregnancy, Postpartum, and Child-Related Health Outcomes: Study Protocol

Author

Strout, Naomi, primary, Pasic, Lana, additional, Hicks, Chloe, additional, Chua, Xin-Yi, additional, Tashvighi, Niki, additional, Butler, Phoebe, additional, Liu, Zhixin, additional, El-Assaad, Fatima, additional, Holmes, Elaine, additional, Susic, Daniella, additional, Samaras, Katherine, additional, Craig, Maria E., additional, Davis, Gregory K., additional, Henry, Amanda, additional, Ledger, William L., additional, and El-Omar, Emad M., additional

Published
2023
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6. Antenatal diet quality and perinatal depression: the Microbiome Understanding in Maternity Study (MUMS) cohort.

Author

Gow, Megan L., Lam, Yei W. I., Jebeile, Hiba, Craig, Maria E., Susic, Daniella, and Henry, Amanda

Subjects
PREVENTION of mental depression, FOOD habits, WEIGHT gain in pregnancy, POSTPARTUM depression, CONFIDENCE intervals, FOOD consumption, FIRST trimester of pregnancy, THIRD trimester of pregnancy, MULTIPLE regression analysis, AGE distribution, NUTRITIONAL requirements, MEDICAL screening, MENTAL health, MANN Whitney U Test, RISK assessment, PSYCHOLOGICAL tests, T-test (Statistics), PEARSON correlation (Statistics), MENTAL depression, HUMAN microbiota, QUESTIONNAIRES, HEALTH behavior, DESCRIPTIVE statistics, CHI-squared test, PARITY (Obstetrics), EXERCISE, RESEARCH funding, DATA analysis software, MICRONUTRIENTS, BODY mass index, EDINBURGH Postnatal Depression Scale, SECONDARY analysis, PREGNANCY
Abstract

Background: Previous findings from research investigating the role of antenatal nutrition in preventing postpartum depression (PPD) are inconsistent. Our primary aim was to investigate the association between pregnancy diet quality and PPD. Our secondary aim was to investigate associations between (a) diet quality and depression during pregnancy and (b) depression during pregnancy and PPD. Methods: This analysis represents data from 73 women participating in the Microbiome Understanding in Maternity Study (MUMS) cohort in Sydney, Australia, which followed women from Trimester 1 of pregnancy to 1‐year postpartum (PP). Participants' diet quality was assessed using the Australian Eating Survey at Trimester 1 and 3 to calculate diet quality, known as the Australian Recommended Food Score (lower diet quality defined as score <39; higher diet quality ≥39). Depression was assessed using the Edinburgh Depression Scale at Trimesters 1, 2, 3 and 6 weeks PP (defined as score ≥11). Results: Depression scores during pregnancy were significantly associated with depression score 6 weeks PP (Trimester 1: r = 0.66, Trimester 2: r = 0.69, Trimester 3: r = 0.67; all p < 0.001). Diet quality during pregnancy was not significantly correlated with 6‐week PPD score. In unadjusted analysis, diet quality during pregnancy was not associated with pregnancy depression scores. When adjusted for age, parity and Trimester 1 body mass index, Trimester 1 physical activity levels and gestational weight gain, higher Trimester 3 diet quality was associated with reduced Trimester 3 depression only. Conclusions: Depression scores during pregnancy were positively associated with PPD, highlighting the importance of screening for depression during pregnancy and postnatally. Larger longitudinal prospective studies may elucidate the association between diet quality and PPD. Highlights: Depression during pregnancy was associated with postpartum depression score, highlighting the importance of adhering to routine screening guidelines throughout the perinatal period.Although diet is clearly important for the health of both the mother and the developing foetus during pregnancy, our analysis of data from the Microbiome Understanding in Maternity Study (MUMS) cohort did not find any associations between diet quality and depression. [ABSTRACT FROM AUTHOR]

Published
2023
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10. J-Edited DIffusional Proton Nuclear Magnetic Resonance Spectroscopic Measurement of Glycoprotein and Supramolecular Phospholipid Biomarkers of Inflammation in Human Serum

Author

Nitschke, Philipp, primary, Lodge, Samantha, additional, Kimhofer, Torben, additional, Masuda, Reika, additional, Bong, Sze-How, additional, Hall, Drew, additional, Schäfer, Hartmut, additional, Spraul, Manfred, additional, Pompe, Nils, additional, Diercks, Tammo, additional, Bernardo-Seisdedos, Ganeko, additional, Mato, José M., additional, Millet, Oscar, additional, Susic, Daniella, additional, Henry, Amanda, additional, El-Omar, Emad M, additional, Holmes, Elaine, additional, Lindon, John C., additional, Nicholson, Jeremy K., additional, and Wist, Julien, additional

Published
2022
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13. Microbiome Understanding in Maternity Study (MUMS), an Australian prospective longitudinal cohort study of maternal and infant microbiota: study protocol

Author

Susic, Daniella, Davis, Gregory, O' Sullivan, Anthony J, McGovern, Emily, Harris, Katie, Roberts, Lynne M, Craig, Maria E, Mangos, George, Hold, Georgina L, El-Omar, Emad M, and Henry, Amanda

Subjects
maternal medicine, obstetrics, Microbiota, microbiology, Australia, Infant, Cohort Studies, paediatrics, Pregnancy, Obstetrics and Gynaecology, Humans, Female, Maternal Health Services, Longitudinal Studies, Prospective Studies
Abstract

Introduction Pregnancy induces significant physiological and cardiometabolic changes, and is associated with alterations in the maternal microbiota. Increasing rates of prepregnancy obesity, metabolic abnormalities and reduced physical activity, all impact negatively on the microbiota causing an imbalance between the commensal microorganisms (termed dysbiosis), which may drive complications, such as gestational diabetes or hypertensive disorders. Considerable work is needed to define the inter-relationships between the microbiome, nutrition, physical activity and pregnancy outcomes. The role of the microbiota during pregnancy remains unclear. The aim of the study is to define microbiota signatures longitudinally throughout pregnancy and the first year post birth, and to identify key clinical and environmental variables that shape the female microbiota profile during and following pregnancy. Methods and analysis The Microbiome Understanding in Maternity Study (MUMS) is an Australian prospective longitudinal cohort study involving 100 mother–infant pairs. Women are enrolled in their first trimester and followed longitudinally. Assessment occurs at

Published
2020

16. More than 6,000 women told us what they wanted for their next pregnancy and birth. Here's what they said.

Author

Keedle, Hazel, Susic, Daniella, and Dahlen, Hannah

Subjects
PREGNANCY, RURAL women, MATERNAL health services, INDUCED labor (Obstetrics), CHILDBIRTH at home, MEDICAL misconceptions
Abstract

Midwifery continuity of care is available now in manypublic hospitals and is commonly called midwifery grouppractice or caseload midwifery. We have also shown an induction of labour in Australia canlead to further medical interventions. Australia has a high rate of induction, especially for womenhaving their first babies (41% induced labour rate forwomen having their first baby). [Extracted from the article]

Published
2023

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