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Instrumen pengukuran kualitas hidup pada pasien kanker telah tervalidasi dan sudah diterjemahkan di banyak negara yaitu salah satunya adalah instrument EORTC QLQ C-30. Hal ini menyebabkan instrument ini telah digunakan pada banyak penelitian di berbagai negara di dunia. Tujuan penelitian ini adalah untuk memberikan gambaran bidang penelitian kualitas hidup menggunakan analisis bibliometrik berdasarkan literature dari tahun 1993 sampai dengan 2021 dan untuk melakukan analisis pola ilmiah penelitian kualitas hidup terutama pada pasien kanker payudara. Metode penelitian ini menggunakan PubMed sebagai database jurnal penelitian yang digunakan dengan strategi pencarian yaitu: ((Kualitas hidup) AND (kanker payudara)) AND (EORTC QLQ), termasuk juga menggunakan MesH terms. Kriteria inklusi pada penelitian ini adalah seluruh penelitian yang menggunakan kuesioner EORTC QLQ sebagai kuesioner kualitas hidup dan semua jenis penelitian, sedangkan artikel review, sistematik review dan meta analisa akan diekslusi dari penelitian ini. Sebanyak 797 artikel diambil dari tahun 1993 sampai dengan 2021. Hasil penelitian menunjukkan bahwa jumlah publikasi meningkat setiap tahun, tetapi volume publikasi masih kurang dari 100 setiap tahun. Pemetaan penulis belum menjangkau semua negara di dunia. Kata perempuan, manusia dan paruh baya adalah kata yang paling banyak disebutkan dalam kata kunci. Kata tersebut dikaitkan dengan faktor-faktor yang dapat mempengaruhi kualitas hidup pasien. Kesimpulan pada penelitian ini adalah jumlah publikasi setiap tahunnya masih cukup rendah (

Anemic in Pregnancy is still a health problem in Indonesia. Iron supplementation is a preventive measure carried out by the government in primary health services. However, the average coverage of national Fe tablets is still not maximal (85.1%). Research related to adherence to iron supplement consumption is still limited, therefore this study aims to determine the relationship between adherence level with anemia of pregnant women. The study used an analytic observational method with a cross sectional approach, conducted in the period August-November 2019 at Jetis I Bantul, primary health service Yogyakarta. A total of 39 respondents who met the inclusion criteria and agreed to informed consent were recruited in this study. Data on the level of compliance were taken through interviewing respondents using quistionnaire and pill count, at least on the 7th day after consuming iron tablets, while Hb levels were taken from medical records and examination of respondents. Statistical analysis was performed using chi square. Results showed that 61.5% of pregnant women complied with the consumption of iron tablets, while the measurement of the pill count showed 59.0% has complience. There was a significant correlation between the consumption of iron tablets and the incidence of pregnancy anemia, both adherence to the questionnaire measurement p = 0.000; OR = 0.050; (CI: 0.010-0.263), or the measurement of pill count p = 0.003; OR = 0.126 (CI: 0.030-0.538). A total of 15.4% of pregnant women have anemia in the 2nd trimester of gestation, and 25.6% in the 3rd trimester. Based on this study, it is concluded that there is a correlation between the level of adherence of Iron tablet consumption towards the incidence of anemia in pregnant women.

Self-medication is one of the efforts that is mostly done by a person in overcoming the symptoms of a minor illness that he is suffering from before consulting a health worker. The results of the 2014 National Basic Reasearch showed that the percentage of the population who chose self-medication or self-medication due to health complaints experienced was 61.05%. Many factors influence people to take treatment, one of which is advertising. The purpose of the study was to determine the relationship between the effect of drug advertising on drug selection decisions and the accuracy of self-medication actions in the community in Umbulharjo District, Yogyakarta City. The design of this study was analytic observational with cross-sectional data collection. The sampling technique used incidental sampling method and data were collected through filling out a validated questionnaire. Data analysis was carried out with univariate and bivariate tests using SPSS 20.0. The results showed that the results of the significance test between the effect of drug advertisements on television on the accuracy of self-medication was 0.864. The conclusion of this study is that advertising has no significant effect on the appropriateness of self-medication (p 0.05).

48.9% of pregnant women in Indonesia in 2018 had anemia. This can affect the health and quality of life of pregnant women. The aim of this study was to investigate the correlation between hemoglobin levels and the quality of life of pregnant women at Jetis 1 Primary Health Care in Bantul, Yogyakarta. This was an observational study with a cross-sectional approach and it was conducted from September to November 2019. The patients’ quality of life was measured by the Indonesian version of the SF-36 questionnaire. The hemoglobin level was mesured by a hemoglobin test. This study used univariate (descriptive) and bivariate data analysis using the Chi-square test. The results showed that there were 12 pregnant women (23.5%) who experienced mild anemia and 13 pregnant women with moderate anemia (25.5%). There was a significant corelation between hemoglobin levels and the quality of life of pregnant women (p < 0.05), especially in the domains of physical health (p = 0.034) and emotional health (p = 0.017). Keywords: anemia, hemoglobin, pregnant women, quality of life

Virus Corona yang ditemukan di Wuhan memberikan tantangan dikalangan petugas kesehatan seperti apoteker yang bertanggung jawab memberikan edukasi kepada masyarakat khususnya terhadap COVID 19. Penelitian ini bertujuan untuk mengukur tingkat pengetahuan, persepsi dan sikap apoteker di apotek Kota Yogyakarta mengenai COVID-19. Desain penelitian adalah observasional analitik dengan populasi apoteker yang berpraktik di apotek Kota Yogyakarta dan sampel penelitian apoteker yang berpraktik di apotek minimal 6 bulan. Hasil penelitian menunjukkan apoteker di apotek kota Yogyakarta memiliki pengetahuan baik mengenai COVID-19 (60%) dan 40% apoteker memiliki pengetahuan yang cukup. Apoteker memiliki persepsi positif sebanyak 66% dan persepsi negatif sebanyak 34% Sikap apoteker menunjukkan 68% positif dan dan 32% negatif. Hubungan tingkat pendidikan dengan pengetahuan, persepsi dan sikap apoteker diperoleh nilai p berturut-turut 0.241, 0.806 dan 0.094, sedangkan hubungan lama pengalaman bekerja dengan pengetahuan, persepsi dan sikap apoteker diperoleh hasil p value berturut- turut 0.010, 0.352, dan 0.022. Kesimpulan penelitian ini adalah apoteker di apotek Kota Yogyakarta memiliki pengetahuan yang baik, persepsi dan sikap positif mengenai COVID-19 serta terdapat hubungan antara lama pengalaman bekerja dengan pengetahuan dan sikap (p

Diabetes mellitus merupakan penyakit kronis yang membuat kadar gula darah meningkat. Bertambahnya usia mempengaruhi kinerja fungsi organ tubuh terhadap insulin mengarah terjadinya fluktuasi gula darah. Turunnya kinerja fungsi tubuh berpengaruh dalam keseimbangan fungsi tubuh yang lain sehingga dapat menyebabkan komplikasi. Tujuan penelitian yaitu mengetahui dan mengevaluasi kadar gula darah berdasarkan usia dan komplikasi penyakit. Rancangan penelitian yang dilakukan adalah penelitian observasional analitik. Pengambilan data dilakukan secara retrospektif dari bulan September - November 2019. Analisis univariat digunakan untuk melihat analisis karakteristik dasar variabel penelitian. Analisis bivariat digunakan untuk mengetahui perbedaan gula darah pasien berdasarkan usia dan komplikasi penyakit. Uji statistik yangdigunakan adalah uji Kruskal Wallis. Hasil penelitian menunjukkan kadar gula darah berdasarkan usia yang diperoleh adalah 0,289; 0,242; 0,150; 0,658; 0,557; 0,711(p > 0,05); 0,040 (p 0,05). Berdasarkan hasil penelitian, dapat disimpulkan tidak ada perbedaan signifikan kadar gula darah pasien berdasarkan usia dan komplikasi penyakit pada periode September 2019–November 2019. Pasien memiliki kadar gula darah yang terkontrol berdasarkan usia dan komplikasi penyakit.

Based on data from WHO (World Health Organization), it is estimated that 41.8% of anemia occurs in pregnant women, with the highest prevalence rate of 61.3% in Africa and 52.5% in Asia. Pharmacist interventions have shown a positive effect in improving therapeutic adherence to hypertensive patients, as well as diabetes mellitus who routinely taking the drugs. The aim of the study was to know effect of giving patient information leaflet (PIL) along with motivational SMS on knowledge, perception, and compliance of pregnant patients in primary care. This study used a quasi-experimental method with pre-post design for two groups, the control group who received the Patient Information leaflet (PIL) and the intervention group who received the Patient Information leaflet (PIL) and motivational SMS from the researcher. Statistical analysis using SPSS with paired t test was used to determine differences in knowledge, perceptions and patient compliance before and after the intervention. Respondents who met the inclusion and exclusion criteria in this study were 74 patients. In the control group the mean score showed a significant difference was the knowledge of iron supplementation with p value= 0.001. Whereas in the treatment group, the mean score showed a significantly different were knowledge of iron supplementation and patient compliance with p values ​​were 0.002 and 0.001.

Anemia pada kehamilan merupakan salah satu masalah dalam kehamilan. Data WHO pada tahun 2001 menunjukkan bahwa lebih dari 50 % wanita hamil mengalami anemia. Anemia pada kehamilan merupakan suatu kondisi dimana kadar hemoglobin kurang dari 11 mg/dL. Prevalensi anemia di Indoensia cukup tinggi yaitu sebesar 50-63%, sedangkan prevalensi di DI Yogyakarta adalah 14,32%. Penelitian mengenai pengetahuan ibu hamil terkait kondisi kehamilannya di Selangor diperoleh bahwa pengetahuan ibu hamil pada kategori baik, namun sebagian besar dari subyek memiliki penegtahuan yang rendah terkait suplemen zat besi. Instrumen penelitian mengenai pengetahuan dan suplemen zat besi yang tervalidasi di Indonesia masih belum ada, sehingga data pengetahuan ibu hamil mengenai kehamilan dan suplemen zat besi masih sangat kurang. Metode dalam penelitian ini adalah dengan melakukan pengembangan instrumen penelitian (kuesioner) yang dilakukan validasi oleh tiga orang ahli di bidangnya masing-masing (validasi konten). Langkah selanjutnya adalah dengan melakukan pilot test untuk mengetahui masukan maupun umpan balik dari subyek terkait kesalahan dan item pertanyaan yang membingungkan. Pilot test juga digunakan untuk mengukur waktu pengisian kuesioner. Langkah terakhir adalah melakukan validasi construct yang dilakukan pada 49 subyek penelitian. Analisis statistik menggunakan pearson correlation dan cronbach alpha digunakan untuk mengukur validitas dan reliabilitas kuesioner. Subyek penelitian dalam validasi ini adalah sebanyak 49 pasien hamil yang mendapatkan suplemen zat besi dan atau asam folat di RS PKU Muhammadiyah Gamping pada periode Agustus sampai dengan September 2019. Berdasarkan hasil Uji validitas terhadap 15 item pertanyaan diperoleh 2 item pertanyaan yang tidak valid, selanjutnya item pertanyaan dihapus dan dilakukan validasi ulang dan diperoleh hasil valid dengan nilai koefisien pearson correlation ditasa nilai r tabel. Hasil uji reliabilitas menggunakan cronbach alpa diperoleh semua item pertanyaan memiliki nilai cronbach alpa diatas 0,6 sehingga dinyatakan reliabel. Kata Kunci: Validasi, pengetahuan, ibu hamil, suplemen zat besi ABSTRACT Anemia in pregnancy is one of the problems in pregnancy. WHO data in 2001 showed that more than 50% of pregnant women had anemia. Anemia in pregnancy is a condition where the hemoglobin level is less than 11 mg / dL. The prevalence of anemia in Indonesia is quite high at 50-63%, while the prevalence in DI Yogyakarta is 14.32%. Research on the knowledge of pregnant women regarding their pregnancy conditions in Selangor shows that the knowledge of pregnant women is in the good category, but most of the subjects have low knowledge regarding iron supplementation. Research instruments on validated knowledge and supplementation of iron in Indonesia still do not exist, so data on knowledge of pregnant women regarding pregnancy and iron supplements is still lacking. The method in this study was to develop a research instrument (questionnaire) which was validated by three experts in their respective fields (content validation). The next step is to conduct a pilot test to find out input and feedback from subjects related to errors and confusing question items. Pilot tests are also used to measure the time to fill out the questionnaire. The final step is to construct validation conducted on 49 research subjects. Statistical analysis using Pearson correlation and Cronbach alpha was used to measure the validity and reliability of the questionnaire. Research subjects in this validation were 49 pregnant patients who received iron supplements and / or folic acid at PKU Muhammadiyah Gamping Hospital in the period of August to September 2019. Based on the results of the validity test of 15 question items, there were 2 items that were invalid, further items questions were deleted and re-validated and valid results obtained with the Pearson correlation coefficient ditasa r table values. The reliability test results using Cronbach Alpha are obtained all questions items have a Cronbach Alpha value above 0.6 so that it is declared reliable. Keywords:validation, knowledge, pregnant women, iron suplements