Search

Your search keyword '"Susan Duthie"' showing total 23 results
Start Over Author "Susan Duthie"
23 results on '"Susan Duthie"'

1. A retrospective audit of neonatal BCG vaccination in Grampian, Scotland

Author

Saba Savul and Susan Duthie

Subjects
Tuberculosis prevention, bacille Calmette–Guerin vaccine, immunization programs, neonatal, BCG immunization, Immunologic diseases. Allergy, RC581-607, Therapeutics. Pharmacology, RM1-950
Abstract

ABSTRACTBacillus Calmette–Guerin (BCG) vaccine confers protection against tuberculosis (TB) and works most effectively when given to infants. Scotland runs a risk-based program in which BCG vaccine is offered to infants whose parent or grandparent was born in a high incidence country for TB. BCG vaccination records for all infants born in Grampian from 1st January 2019 to 31st December 2021 were reviewed from Nov 2022 to Feb 2023. Three electronic databases were examined, i.e. BadgerNet, Scottish Immunisation Recall System and TrakCare. Data were analyzed using Microsoft Excel 2013. Out of a total of 16,078 live births in the 3-year study period, 2060 met the criteria for offering BCG vaccination. The uptake level was 93% in 2019, 89% in 2020 (in the midst of the COVID-19 pandemic) and 93% in 2021. Audit results demonstrated higher uptake than the 85% key performance indicator target within the 2018 Scottish TB Framework and improvement in vaccination rates as compared to earlier rates of 86% in 2012 and 90% in 2013 in Grampian. Strengthening electronic systems and enhancing awareness regarding TB and the BCG vaccine can further progress BCG vaccination uptake.

Published
2023
Full Text
View/download PDF

2. Effects of wheat and oat-based whole grain foods on serum lipoprotein size and distribution in overweight middle aged people: a randomised controlled trial.

Author

Paula Tighe, Garry Duthie, Julie Brittenden, Nicholas Vaughan, William Mutch, William G Simpson, Susan Duthie, Graham W Horgan, and Frank Thies

Subjects
Medicine, Science
Abstract

INTRODUCTION: Epidemiological studies suggest three daily servings of whole-grain foods (WGF) might lower cardiovascular disease risk, at least partly by lowering serum lipid levels. We have assessed the effects of consuming three daily portions of wholegrain food (provided as wheat or a mixture of wheat and oats) on lipoprotein subclass size and concentration in a dietary randomised controlled trial involving middle aged healthy individuals. METHODS: After a 4-week run-in period on a refined diet, volunteers were randomly allocated to a control (refined diet), wheat, or wheat + oats group for 12 weeks. Our servings were determined in order to significantly increase the intakes of non starch polysaccharides to the UK Dietary Reference Value of 18 g per day in the whole grain groups (18.5 g and 16.8 g per day in the wheat and wheat + oats groups respectively in comparison with 11.3 g per day in the control group). Outcome measures were serum lipoprotein subclasses' size and concentration. Habitual dietary intake was assessed prior and during the intervention. Of the 233 volunteers recruited, 24 withdrew and 3 were excluded. RESULTS: At baseline, significant associations were found between lipoprotein size and subclasses' concentrations and some markers of cardiovascular risk such as insulin resistance, blood pressure and serum Inter cellular adhesion molecule 1 concentration. Furthermore, alcohol and vitamin C intake were positively associated with an anti-atherogenic lipoprotein profile, with regards to lipoprotein size and subclasses' distribution. However, none of the interventions with whole grain affected lipoprotein size and profile. CONCLUSION: Our results indicate that three portions of wholegrain foods, irrelevant of the type (wheat or oat-based) do not reduce cardiovascular risk by beneficially altering the size and distribution of lipoprotein subclasses. TRIAL REGISTRATION: www.Controlled-Trials.com ISRCTN 27657880.

Published
2013
Full Text
View/download PDF

3. Phenome-wide association study of genetically predicted B vitamins and homocysteine biomarkers with multiple health and disease outcomes:analysis of the UK Biobank

Author

Lijuan Wang, Xue Li, Azita Montazeri, Amanda J. MacFarlane, Franco Momoli, Susan Duthie, Marjanne Senekal, Ines Mesa Eguiagaray, Ron Munger, Derrick Bennett, Harry Campbell, Michele Rubini, Helene McNulty, Julian Little, and Evropi Theodoratou

Subjects
Nutrition and Dietetics, Vitamin K, Medicine (miscellaneous), Mendelian Randomization Analysis, Article, United Kingdom, Vitamin B 6, Vitamin B 12, Folic Acid, Pregnancy, Vitamin B Complex, Humans, Female, Vitamin A, Homocysteine, Biomarkers, Biological Specimen Banks
Abstract

BACKGROUND: Although a number of health outcomes such as cardiovascular diseases, metabolic-related outcomes, neurological disorders, pregnancy outcomes and cancers have been identified in relation to B vitamins, evidence is of uneven quality and volume, and there is uncertainty about putative causal relationships. OBJECTIVES: To explore the effects of B vitamins and homocysteine on a wide range of health outcomes based on a large biorepository linking biological samples and electronic medical records. METHODS: First, we performed a phenome-wide association study (PheWAS) to investigate associations of genetically predicted plasma concentrations (genetic component of the circulating concentrations) of folate, vitamin B6, vitamin B12 and their metabolite homocysteine with a wide range of disease outcomes (including both prevalent and incident events) among 385,917 individuals in the UK Biobank. Second, two-sample Mendelian randomization (MR) analysis was used to replicate any observed associations and detect causality. We considered MR p

Published
2023
Full Text
View/download PDF

4. How good is our neonatal BCG uptake? A snapshot in Grampian

Author

Susan Duthie and Sarah Shanks

Subjects
Pediatrics, medicine.medical_specialty, Tuberculosis, 03 medical and health sciences, 0302 clinical medicine, Risk Factors, medicine, Humans, 030212 general & internal medicine, Tuberculosis, Pulmonary, Risk status, business.industry, Immunization Programs, Public health, Public Health, Environmental and Occupational Health, Infant, Newborn, Infant, General Medicine, medicine.disease, Bcg immunisation, Vaccination, 030228 respiratory system, Scotland, Vaccination coverage, BCG Vaccine, Immunisation recall, business, BCG vaccine
Abstract

Background The Neonatal BCG Immunisation programme is a key part of tuberculosis (TB) control efforts in the UK; however, there is considerable variability in the method of delivery of the programme and monitoring of performance. This study aimed to review the extent to which infants at risk of exposure to TB are being identified in Grampian and to assess the uptake of BCG vaccination in eligible infants. Methods The Practitioner Services database and Scottish Immunisation Recall System records for all babies born in Grampian in 2012 and 2013 were reviewed to identify the number of babies who had a TB risk status recorded and to assess the uptake of BCG immunization in at-risk babies. Results The proportion of babies with a risk status recorded was 96.6% in 2012 and 95.5% in 2013. The uptake of BCG vaccination in at-risk babies was 85.9% in 2012 and 89.9% in 2013. Conclusions NHS Grampian has an efficient method for identifying infants at risk of exposure to TB and has good neonatal BCG vaccination coverage.

Published
2015

7. Abstract P073: Increased Consumption of Wheat and Oat-based Wholegrain Foods does not Affect Serum Lipids and Lipoprotein Size and Distribution in Healthy Middle Aged People

Author

Paula Tighe, Nick Vaughan, Garry Duthie, Julie Brittenden, William G Simpson, Susan Duthie, Graham Horgan, and Frank Thies

Subjects
Physiology (medical), food and beverages, Cardiology and Cardiovascular Medicine
Abstract

Epidemiological studies suggest three daily servings of whole-grain foods (WGF) might lower cardiovascular disease (CVD) risk, at least partly by lowering serum lipid levels. Wheat and oats, the main WGF consumed in the UK, might induce different lipid responses. We aimed to assess the effects of three daily portions of WGF (provided as a mixture of wheat and oats or only wheat) on lipoprotein subclasses size and concentration. A dietary randomised controlled trial involving 233 middle aged healthy individuals was carried out. After a 4weeks run-in period on a refined diet, volunteers were randomly allocated to a control (refined diet), wheat or wheat + oats group for 12 weeks. Outcome measures were serum cholesterol as well as lipoprotein subclasses size and concentration, as measured by nuclear magnetic resonance. Blood lipid levels remained unchanged after 12 weeks intervention with WGF, whereas serum total- and LDL- cholesterol concentrations decreased slightly but significantly in the refined group compared with the wheat group. However, these changes were not associated with differences in lipoprotein subclasses’ size and concentration. Our results indicate that three portions of WGF, irrelevant of the type (wheat or oat-based) do not reduce cardiovascular risk by altering beneficially the size and distribution of lipoprotein subclasses.

Published
2012
Full Text
View/download PDF

8. Guidelines for the determination of brain death in infants and children: an update of the 1987 Task Force recommendations

Author

Maureen A. Madden, Amit Vohra, Derek Andrew Bruce, Vicki L. Montgomery, Jacqueline A. Williams-Phillips, Daniel Lebovitz, Shannon E. G. Hamrick, Andrea M. Kline, Mohan R. Mysore, Rick Harrison, Edward E. Conway, Mudit Mathur, Stephen Ashwal, Jeffrey M. Perlman, Nancy K. Rollins, Sam D. Shemie, Susan Duthie, and Thomas A. Nakagawa

Subjects
medicine.medical_specialty, Brain Death, Task force, business.industry, MEDLINE, Poison control, Human factors and ergonomics, Critical Care and Intensive Care Medicine, medicine.disease, Occupational safety and health, Pediatric brain, Injury prevention, medicine, Humans, Medical emergency, Grading (education), Intensive care medicine, business
Abstract

To review and revise the 1987 pediatric brain death guidelines.Relevant literature was reviewed. Recommendations were developed using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system.1) Determination of brain death in term newborns, infants, and children is a clinical diagnosis based on the absence of neurologic function with a known irreversible cause of coma. Because of insufficient data in the literature, recommendations for preterm infants37 wks gestational age are not included in this guideline. 2) Hypotension, hypothermia, and metabolic disturbances should be treated and corrected and medications that can interfere with the neurologic examination and apnea testing should be discontinued allowing for adequate clearance before proceeding with these evaluations. 3) Two examinations, including apnea testing with each examination separated by an observation period, are required. Examinations should be performed by different attending physicians. Apnea testing may be performed by the same physician. An observation period of 24 hrs for term newborns (37 wks gestational age) to 30 days of age and 12 hrs for infants and children (30 days to 18 yrs) is recommended. The first examination determines the child has met the accepted neurologic examination criteria for brain death. The second examination confirms brain death based on an unchanged and irreversible condition. Assessment of neurologic function after cardiopulmonary resuscitation or other severe acute brain injuries should be deferred for ≥24 hrs if there are concerns or inconsistencies in the examination. 4) Apnea testing to support the diagnosis of brain death must be performed safely and requires documentation of an arterial Paco2 20 mm Hg above the baseline and ≥60 mm Hg with no respiratory effort during the testing period. If the apnea test cannot be safely completed, an ancillary study should be performed. 5) Ancillary studies (electroencephalogram and radionuclide cerebral blood flow) are not required to establish brain death and are not a substitute for the neurologic examination. Ancillary studies may be used to assist the clinician in making the diagnosis of brain death a) when components of the examination or apnea testing cannot be completed safely as a result of the underlying medical condition of the patient; b) if there is uncertainty about the results of the neurologic examination; c) if a medication effect may be present; or d) to reduce the interexamination observation period. When ancillary studies are used, a second clinical examination and apnea test should be performed and components that can be completed must remain consistent with brain death. In this instance, the observation interval may be shortened and the second neurologic examination and apnea test (or all components that are able to be completed safely) can be performed at any time thereafter. 6) Death is declared when these criteria are fulfilled.

Published
2011

10. Contributors

Author

Edward Abraham, Peter Abrams, Kareem Abu-Elmagd, Yasir Abu-Omar, Carlos Agustí, William C. Aird, Philip Alapat, Ali H. Al-Khafaji, Gustavo G. Angaramo, Derek C. Angus, Anastasia Antoniadou, Anupam Anupam, Andrew C. Argent, John H. Arnold, Anna Arroyo, Stephen Ashwal, Mark E. Astiz, Elie Azoulay, Omer A. Bajwa, Anthony Baldea, Marie R. Baldisseri, Zsolt J. Balogh, Rasheed Abiodun Balogun, Arna Banerjee, Philip S. Barie, Brendan Barrett, Robert Bartlett, John G. Bartlett, Gianluigi Li Bassi, Sarice L. Bassin, Julie A. Bastarache, Colin Bauer, Daniel G. Bausch, Hülya Bayýr, David T. Bearden, Gregory J. Beilman, Rinaldo Bellomo, E. David Bennett, Gordon R. Bernard, Jay K. Bhama, Joost J.L.M. Bierens, Walter L. Biffl, Thomas P. Bleck, Thomas A. Bledsoe, Karen C. Bloch, Frank Bloos, Desmond Bohn, Nicole C. Bouchard, Arthur J. Boujoukos, William J. Brady, Serge Brimioulle, Daniel E. Brooks, Richard C. Brundage, Jeffrey P. Burns, Belén Cabello, Karen H. Calhoun, Clifton W. Callaway, Peter M.A. Calverley, John Camm, Diane M. Cappelletty, Joseph A. Carcillo, Anthony J. Carlese, Juan Carlos-Puyana, Franco A. Carnevale, Edward D. Chan, Sanjay Chawla, Lakshmipathi Chelluri, David C. Chen, Annie S. Chevrier, Su Min Cho, Robert S.B. Clark, Michael A. Coady, Stephen M. Cohn, Alan D. Cook, Deborah J. Cook, Robert N. Cooney, Susan J. Corbridge, Thomas C. Corbridge, Howard L. Corwin, Mark A. Crowther, Burke A. Cunha, Cheston B. Cunha, J. Randall Curtis, Vincenzo D’Intini, Pirouz Daeihagh, Joseph M. Darby, James M. Dargin, Michaël Darmon, Joseph F. Dasta, John D. Davies, Robert W. Derlet, Mark Dershwitz, Anne Marie G.A. de Smet, Monica Dhand, Anahat Dhillon, Rajeev Dhupar, Michael N. Diringer, Peter Doelken, Michael Donahoe, Timothy R. Donahue, David J. Dries, Thomas D. DuBose, Susan Duthie, Randy Edwards, Philippe Eggimann, Waleed A. Elhassan, E. Wesley Ely, Guillaume Emeriaud, Gregory A. Eschenauer, Joel H. Ettinger, Joshua H. Ettinger, David Clay Evans, Gregory T. Everson, Derek V. Exner, Ronald J. Falk, Jeremy Farrar, Alan P. Farwell, Kathryn Felmet, Niall D. Ferguson, Miguel Ferrer, Mitchell P. Fink, Ericka L. Fink, Douglas N. Fish, Diana F. Florescu, Brett E. Fortune, Bradley D. Freeman, Blake Froberg, John J. Fung, Brent Furbee, Richard L. Gamelli, Raúl J. Gazmuri, Robert H. Geelkerken, Todd W.B. Gehr, Michael A. Gentile, M. Patricia George, Herwig Gerlach, R. Mark Ghobrial, Helen Giamarellou, Fredric Ginsberg, Thomas G. Gleason, Jacques P. Goldstein, Hernando Gomez, Sherilyn Gordon Burroughs, Jeremy David Gradon, Cornelia R. Graves, Cesare Gregoretti, Jeffrey S. Groeger, R. Michael Grounds, Paul O. Gubbins, Kyle J. Gunnerson, Fahim A. Habib, Mitchell L. Halperin, Mary E. Hartman, Maurene A. Harvey, Moustafa A. Hassan, Yoshiro Hayashi, Jan A. Hazelzet, Stephen O. Heard, Paul C. Hébert, Elizabeth D. Hermsen, Daren K. Heyland, Jonathan R. Hiatt, Robert W. Hickey, Tran Tinh Hien, Thomas L. Higgins, Nicholas S. Hill, Horacio Hojman, Steven M. Hollenberg, J. Terrill Huggins, David T. Huang, Christopher G. Hughes, Russell D. Hull, Margaret Isaac, James P. Isbister, Connie Jastremski, Larry Jenkins, Paul Jodka, Robert G. Johnson, Philippe G. Jorens, Vern C. Juel, Rose Jung, Christina R. Kahl, Andre C. Kalil, Edo Kaluski, Kamel S. Kamel, Sandra Kane-Gill, Jeffrey P. Kanne, Lionel Karlin, Marinka Kartalija, James Kasiewicz, Kenneth D. Katz, David Kaufman, John A. Kellum, Rick Kingston, Orlando C. Kirton, Kurt Kleinschmidt, Jason Knight, Patrick M. Kochanek, W. Andrew Kofke, Jeroen J. Kolkman, Robert L. Kormos, Rosemary A. Kozar, David J. Kramer, John W. Kreit, James A. Kruse, Anand Kumar, Vladimir Kvetan, Jacques Lacroix, Gilles Lebuffe, Virginie Lemiale, Angela M. Leung, Sharon Leung, Allan D. Levi, Phillip D. Levin, Mitchell M. Levy, Mah Chou Liang, Scott Liebman, Stuart L. Linas, Gregory Y.H. Lip, Pamela A. Lipsett, Alan Lisbon, Carmen Lucena, Andrew I.R. Maas, Neil R. MacIntyre, Duncan Macrae, Bernhard Maisch, Amer M. Malik, Jordi Mancebo, Henry J. Mann, Sanjay Manocha, Stéphane Manzo-Silberman, Paul E. Marik, John J. Marini, Donald W. Marion, Steven J. Martin, Alvaro Martinez-Camacho, Anne Marie Mattingly, Gary R. Matzke, Adeline Max, George V. Mazariegos, Joanne Mazzarelli, Stephen A. McClave, Ryan M. McEnaney, John K. McIllwaine, Michelle K. McNutt, Sangeeta Mehta, Dieter Mesotten, Kimberly S. Meyer, David J. Michelson, Saar Minha, Marek A. Mirski, Rima A. Mohammad, Xavier Monnet, Frederick A. Moore, Laura J. Moore, Anne-Sophie Moreau, Delphine Moreau, Alison Morris, Amy E. Morris, Bruno Mourvillier, Mark A. Munger, Raghavan Murugan, Claus-Martin Muth, Kurt G. Naber, Lena M. Napolitano, Stanley A. Nasraway, Jovany Cruz Navarro, Lewis S. Nelson, Michael S. Niederman, Jessica C. Njoku, Scott Norwood, Juan B. Ochoa, Mark D. Okusa, Keith M. Olsen, Steven M. Opal, James P. Orlowski, Catherine M. Otto, Heleen M. Oudemans-van Straaten, Pratik P. Pandharipande, Joseph E. Parrillo, David L. Paterson, Frédéric L. Paulin, Andrew B. Peitzman, Daleen Aragon Penoyer, Bradley Peterson, Graham F. Pineo, Michael R. Pinsky, Greta Piper, Didier Pittet, Fred Plum, Murray M. Pollack, Lucido L. Ponce, Robert Pousman, Peter J. Pronovost, Przemyslaw B. Radwański, Thomas G. Rainey, Thomas Rajan, Vito Marco Ranieri, Konrad Reinhart, Jorge Reyes, Andrew Rhodes, Zaccaria Ricci, Christian Richard, John R. Richards, John Riordan, Arsen D. Ristic, Sandro Rizoli, Claudia S. Robertson, Emmanuel Robin, Ferran Roche-Campo, Paul Rogers, Claudio Ronco, John C. Rotschafer, Gordon D. Rubenfeld, Randall A. Ruppel, Laura T. Russo, Daniel E. Rusyniak, Steven A. Sahn, Juan C. Salgado, Cristina Santonocito, Penny Lynn Sappington, John Sarko, Richard H. Savel, Irina Savelieva, Benoit Schlemmer, Minka Schofield, Kristine S. Schonder, Anton C. Schoolwerth, Robert W. Schrier, Carl Schulman, Evan Schwarz, Aaron M. Scifres, Donna L. Seger, Amelie Seguin, Frank W. Sellke, Sajid Shahul, M. Khaled Shamseddin, Erik S. Shank, Eduard Shantsila, Kapil Sharma, Robert L. Sheridan, Ariel L. Shiloh, Debra J. Skaar, Anthony D. Slonim, Teresa L. Smith Jacobs, Pablo Solís-Muñoz, Michael D. Sosin, Charles L. Sprung, Vincenzo Squadrone, Thomas E. Starzl, Steven M. Steinberg, David M. Steinhorn, Eric J. Stern, Thomas E. Stewart, Nino Stocchetti, Joerg-Patrick Stübgen, Sanjay Subramanian, Justin Szawlewicz, David Szpilman, David P. Taggart, Daniel Talmor, Jean-Louis Teboul, Isaac Teitelbaum, Stephen R. Thom, C. Louise Thwaites, Jean-François Timsit, Alan Tinmouth, Samuel A. Tisherman, S. Rob Todd, Antoni Torres, Robert D. Truog, Krista Turner, Edith Tzeng, Nir Uriel, Benoit Vallet, Greet Van den Berghe, P. Vernon van Heerden, Benjamin W. Van Tassell, Frédéric Vanden Eynden, Olivier Varenne, Ramesh Venkataraman, Kathleen M. Ventre, Zvi Vered, Jean-Louis Vincent, Elizabeth A. Vitarbo, Louis Voigt, Florian M.E. Wagenlehner, Christina J. Wai, Keith R. Walley, Nicholas S. Ward, Lorraine B. Ware, Robert J. Weber, Lawrence R. Wechsler, David Weill, Craig R. Weinert, Julia Wendon, Michel Wolff, Benjamin Wrigley, Richard G. Wunderink, Lam M. Yen, Sergio L. Zanotti-Cavazzoni, Allyson R. Zazulia, Janice Zimmerman, and Walter Zingg

Published
2011
Full Text
View/download PDF

11. Contributors

Author

Veda L. Ackerman, P. David Adelson, Rachel S. Agbeko, Melvin C. Almodovar, Estella M. Alonso, Raj K. Aneja, Derek C. Angus, Andrew C. Argent, Francois P. Aspesberro, Adnan M. Bakar, Barbara Bambach, Lee M. Bass, Hülya Bayir, Pierre Beaulieu, Michael J. Bell, M.A. Bender, Jeffrey C. Benson, Wade W. Benton, Robert A. Berg, Darryl H. Berkowitz, Omar J. Bhutta, Katherine C. Biagas, Julie Blatt, Douglas L. Blowey, Jeffrey L. Blumer, John S Bradley, Barbara W. Brandom, Linda Brodsky, Thomas V. Brogan, Adam W. Brothers, Timothy E. Bunchman, Randall S. Burd, Jeffrey Burns, Sean P. Bush, Louis L. Bystrak, Angela J.P. Campbell, Christopher R. Cannavino, Joseph A. Carcillo, Hector Carrillo-Lopez, Antonio Cassara, Michael G. Caty, John R. Charpie, Adrian Chavez, John C. Christenson, Jonna D. Clark, Robert S.B. Clark, Katherine C. Clement, Jacqueline J. Coalson, Craig M. Coopersmith, Christopher P. Coppola, Seth J. Corey, Peter N. Cox, James J. Cummings, Martha A.Q. Curley, Marek Czosnyka, Christopher A. D’Angelis, Mary K. Dahmer, Heidi J. Dalton, Peter J. Davis, M. Theresa de la Morena, Cláudio Flauzino de Oliveira, Sonny Dhanani, Emily L. Dobyns, Elizabeth J. Donner, Lesley Doughty, Didier Dreyfuss, Christine Duncan, Philippe Durand, Susan Duthie, Howard Eigen, Waleed M. Maamoun El-Dawy, Steven Elliott, Helen M. Emery, Mauricio A. Escobar, Jacqueline M. Evans, Kate Felmet, Jeffrey R. Fineman, Ericka L. Fink, Richard T. Fiser, Frank A. Fish, James E. Fletcher, Michael J. Forbes, Amber E. Fort, Norman Fost, Joel E. Frader, Deborah E. Franzon, F. Jay Fricker, Stuart Friess, Bradley P. Fuhrman, Xiomara Garcia-Casal, France Gauvin, J. William Gaynor, Eli Gilad, James C. Gilbert, Nicole S. Glaser, Stuart L. Goldstein, Denise M. Goodman, Ana Lía Graciano, Björn Gunnarsson, Cecil D. Hahn, Mark Hall, Melinda Fiedor Hamilton, Yong Y. Han, Cherissa Hanson, Cary O. Harding, Mary E. Hartman, Jan A. Hazelzet, Christopher M.B. Heard, Ann Marie Heine, Lynn J. Hernan, Jeremy S. Hertzig, Mark J. Heulitt, Julien I.E. Hoffman, James C. Huhta, Rebecca Ichord, Andrew Inglis, Gretchen A. Linggi Irby, Brian Jacobs, David Jardine, Alberto Jarillo-Quijada, Etienne Javouey, Christa C. Jefferis Kirk, James A. Johns, Prashant Joshi, Richard J. Kagan, Prince J. Kannankeril, Robert K. Kanter, Oliver Karam, Kevin R. Kasten, Michael Kelly, Paritosh C. Khanna, Patrick M. Kochanek, Keith C. Kocis, Samuel A. Kocoshis, Ildiko H. Koves, Thomas J. Kulik, Vasanth H. Kumar, Jacques Lacroix, Satyan Lakshminrusimha, Joanne M. Langley, Peter C. Laussen, Daniel L. Levin, Mithya Lewis-Newby, Mary W. Lieh-Lai, Daphne Lindsey, Catherine Litalien, Robert E. Lynch, Amy T. Makley, James P. Marcin, Mary Michele Mariscalco, Barry Markovitz, Lynn D. Martin, Norma J. Maxvold, Paula M. Mazur, Jennifer A. McArthur, Jerry McLaughlin, Gwenn E. McLaughlin, Karen McNiece Redwine, Nilesh M. Mehta, Renuka Mehta, Ann J. Melvin, Sharad Menon, Ayesa N. Mian, Kelly Michelson, Kelly A. Michienzi, Patricia A. Moloney-Harmon, Paul Monagle, Michele M. Moss, Steven S. Mou, Jared T. Muenzer, Vinay Nadkarni, Thomas A. Nakagawa, Navyn Naran, Trung Nguyen, Carol E. Nicholson, Katie R. Nielsen, Tracie Northway, Victoria F. Norwood, Daniel A. Notterman, Jeffrey E. Nowak, Peter Oishi, Richard A. Orr, Yves Ouellette, Daiva Parakininkas, Margaret M. Parker, Tony Pearson-Shaver, J. Julio Pérez Fontán, Mark Peters, Catherine Pihoker, Maury N. Pinsk, Murray M. Pollack, Steven Pon, Michael Quasney, Surender Rajasekaran, Sally E. Rampersad, Suchitra Ranjit, Erin P. Reade, James J. Reese Jr., Monica Relvas, Kenneth E. Remy, Jean-Damien Ricard, Tom B. Rice, Debra Ann Ridling, Joan S. Roberts, Ashley S. Ross, Kimberly R. Roth, Alexandre T. Rotta, Mark E. Rowin, John Roy, Christopher M. Rubino, Randall A. Ruppel, Cynda H. Rushton, Rita M. Ryan, Rosanne Salonia, Joshua Salvin, Ronald C. Sanders Jr., Ajit A. Sarnaik, Ashok P. Sarnaik, Georges Saumon, Robert Sawin, Matthew C. Scanlon, Kenneth A. Schenkman, Stephen M. Schexnayder, Charles L. Schleien, George J. Schwartz, Steven M. Schwartz, Frank Shann, Dennis W.W. Shaw, Sam D. Shemie, Mish Shoykhet, V. Ben Sivarajan, Peter W. Skippen, Anthony D. Slonim, Laurie Smith, Lincoln S. Smith, Stephen W. Standage, Joel B. Steinberg, David M. Steinhorn, Sasko D. Stojanovski, Elizabeth A. Storm, Michael H. Stroud, Marc G. Sturgill, Robert M. Sutton, Jordan M. Symons, Muayyad Tailounie, Julie-An Talano, Robert Tamburro Jr., Robert C. Tasker, Ann E. Thompson, Ann H. Tilton, Alan Tinmouth, Joseph D. Tobias, Nicole H. Tobin, I. David Todres, Marisa Tucci, Kalia P. Ulate, Kevin M. Valentine, David J. Vaughan, Shekhar T. Venkataraman, Mihaela Visoiu, Amélie von Saint André–von Arnim, Mark S. Wainwright, Martin K. Wakeham, R. Scott Watson, Ashley N. Webb, Carl Weigle, Maria B. Weimer, David L. Wessel, Randall C. Wetzel, Hector R. Wong, Ellen G. Wood, Alan D. Woolf, James J. Woytash, Ofer Yanay, Arno Zaritsky, Danielle M. Zerr, and Jerry J. Zimmerman

Published
2011
Full Text
View/download PDF

13. [Untitled]

Author

Bradley M. Peterson, Whitney Law, David Shellington, and Susan Duthie

Subjects
Pleural drainage, medicine.medical_specialty, business.industry, Antithrombin, medicine, Critical Care and Intensive Care Medicine, business, medicine.drug, Surgery
Published
2015
Full Text
View/download PDF

14. Contributors

Author

P. David Adelson, David B. Allen, Estella M. Alonso, Gülay Pinar Alper, Derek C. Angus, Sidney Anthone, Andrew Argent, John H. Arnold, Barbara Bambach, Hülya Bayir, Pierre Beaulieu, Laurie O. Beitz, Jorge R. Beltrán, Wade W. Benton, Robert A. Berg, Ira Bergman, Julie Blatt, Douglas L. Blowey, Jeffrey L. Blumer, John S. Bradley, Barbara W. Brandom, Martin L. Brecher, Richard J. Brilli, Guy F. Brisseau, Thomas V. Brogan, Timothy E. Bunchman, Sean P. Bush, Joseph Carcillo, Aaron L. Carrel, Hector Carrillo-Lopez, Victoria Cartwright, Hugo F. Carvajal, Leticia Castillo, Michael G. Caty, Pelin Cengiz, Anthony C. Chang, John R. Charpie, Adrián Chávez, Russell W. Chesney, Michael A. Cimino, Robert S.B. Clark, Jacqueline J. Coalson, D. Ryan Cook, Craig M. Coopersmith, Christopher P. Coppola, Seth J. Corey, Peter N. Cox, Kathleen Culver, James J. Cummings, Martha A.Q. Curley, Marek Czosnyka, Heidi J. Dalton, Stéphane Dauger, Peter J. Davis, Jenina Deshler, Sonny Dhanani, Rhonda M. Dick, Emily L. Dobyns, Elizabeth J. Donner, Didier Dreyfuss, Philippe Durand, Susan Duthie, Richard G. Ellenbogen, Jacqueline Evans, James C. Fackler, Kathryn Felmet, Jeffrey R. Fineman, Debra H. Fiser, Frank A. Fish, James E. Fletcher, J. Julio Pérez Fontán, Michael L. Forbes, Norman Fost, Joel E. Frader, Deborah Franzon, F. Jay Fricker, Aaron L. Friedman, Bradley P. Fuhrman, France Gauvin, Eli Gilad, James C. Gilbert, Brett P. Giroir, Stuart L. Goldstein, James Graham, Jerril W. Green, Thomas P. Green, Stephanie Greene, James A. Griffith, Mauro Grossi, Björn Gunnarsson, Scott A. Hagen, Cecil D. Hahn, Craig Hallstrom, Yong Y. Han, Cary O. Harding, William G. Harmon, Eric Harry, Mary E. Hartman, Christopher Heard, Lynn Hernan, Mark J. Heulitt, Robert W. Hickey, Julien I.E. Hoffman, Karen T. Hofmann, Gregory A. Hollman, James C. Huhta, Hector E. James, David Jardine, Alberto Jarillo, Etienne Javouey, James A. Johns, Kristin K. Johnson, Michael V. Johnston, Deborah P. Jones, Prashant Joshi, Prince J. Kannankeril, Robert K. Kanter, John A. Kellum, Michael Kelly, Patrick M. Kochanek, Samuel A. Kocoshis, Thomas J. Kulik, Vasanth H. Kumar, Jacques Lacroix, Yichen Lai, Joanne M. Langley, Stanley T. Lau, Peter Laussen, Yi-Horng Lee, Mary W. Lieh-Lai, D. Michael Lindsay, Catherine Litalien, Naomi L.C. Luban, Robert E. Lynch, Frank Maffei, James P. Marcin, Mary Michele Mariscalco, Barry P. Markovitz, Lynn D. Martin, Anne G. Matlow, John E. Mayer, Paula Mazur, E. Dean McKenzie, Gwenn E. McLaughlin, Nilesh Mehta, Renuka Mehta, Ann J. Melvin, Jean-Christophe Mercier, Kelly Michelson, Kelly A. Michienzi, Patricia A. Moloney-Harmon, Frederick C. Morin, Michele Moss, Vinay Nadkarni, Carol E. Nicholson, Victoria F. Norwood, Daniel Notterman, Alan Nugent, Peter Oishi, Victor Olivar, Richard A. Orr, Yves Ouellette, Daiva Parakininkas, Margaret M. Parker, Anthony L. Pearson-Shaver, Mary Jane F. Petruzzi, Maury N. Pinsk, Murray M. Pollack, Steven Pon, Alice Pong, Lara Primak, Audra Prince, Jean-Damien Ricard, Tom B. Rice, Gail E. Richards, Debra Ann Ridling, Joan Roberts, Kimberly Roth, Alexandre T. Rotta, Daniel Rubens, Jeffrey S. Rubenstein, Christopher M. Rubino, Randall Ruppel, Peter J. Safar, Ashok P. Sarnaik, Joel B. Sarner, Georges Saumon, Matthew C. Scanlon, Kenneth Schenkman, Stephen M. Schexnayder, Charles L. Schleien, Timothy A. Sentongo, Thomas P. Shanley, Frank Shann, Dennis W.W. Shaw, Sam D. Shemie, Peter Skippen, Anthony D. Slonim, Laurie Smith, Lincoln Smith, David M. Steinhorn, Waldemar E. Storm, Marc Sturgill, Marianne T. Sweetser, Jordan M. Symons, Robert C. Tasker, Ann E. Thompson, Ann Henderson Tilton, Nicole H. Tobin, I. David Todres, Peter Trinkaus, David J. Vaughan, Shekhar T. Venkataraman, Rapheus C.Q. Villanueva, Patricia C. Wankum, R. Scott Watson, Wayne R. Waz, Carl G.M. Weigle, Maria B. Weimer, Ed Weinberger, David L. Wessel, William T. West, Randall C. Wetzel, Dale Whitby, Hector R. Wong, Ellen G. Wood, Alan D. Woolf, James Woytash, Ofer Yanay, Arno Zaritsky, Danielle M. Zerr, and Jerry J. Zimmerman

Published
2006
Full Text
View/download PDF

16. Neurogenic Pulmonary Edema Associated With Pediatric Status Epilepticus

Author

Susan Duthie, Karin Reuter-Rice, and Justin Hamrick

Subjects
Respiratory arrest, Central nervous system, Pulmonary Edema, Status epilepticus, Pathogenesis, Status Epilepticus, Recurrence, Intubation, Intratracheal, medicine, Humans, Cardiac Output, Respiratory system, Emergency Treatment, Depression (differential diagnoses), business.industry, General Medicine, Hypoxia (medical), Pulmonary edema, medicine.disease, Oxygen, medicine.anatomical_structure, Child, Preschool, Anesthesia, Pediatrics, Perinatology and Child Health, Emergency Medicine, Female, medicine.symptom, business
Abstract

Neurogenic pulmonary edema (NPE) can result from various central nervous system disorders such as brain malignancies, traumatic brain injuries, infections, and seizures. Although the pathogenesis is not completely understood, NPE creates an increase in pulmonary interstitial and alveolar fluid. In adults, it has been reported with prolonged seizure activity. In pediatric patients, pulmonary edema has rarely been reported after status epilepticus, and respiratory compromise is most often due to anticonvulsant-related respiratory depression. Treatment for NPE is largely supportive. If unrecognized, it can lead to hypoxia and respiratory arrest. We report a case of status epilepticus-related pulmonary edema in a female toddler, the youngest patient to be reported in the literature.

Published
2011
Full Text
View/download PDF

17. [Untitled]

Author

Jennifer Foley, Phi-yen Nguyen Bui, Vishal Nigam, Susan Duthie, John J. Lamberti, David Shellington, Bradley M. Peterson, and Gabe Vaughn

Subjects
medicine.medical_specialty, Heart disease, law, business.industry, Anesthesia, Internal medicine, Cardiopulmonary bypass, Cardiology, medicine, Critical Care and Intensive Care Medicine, business, medicine.disease, law.invention
Published
2014
Full Text
View/download PDF

18. Pediatric acute hemorrhagic leukoencephalitis: report of a surviving patient and review

Author

John S. Bradley, Hal S. Meltzer, Christopher E. Dory, John A. D. Leake, Glenn F. Billman, Mark Nespeca, and Susan Duthie

Subjects
Microbiology (medical), Pediatrics, medicine.medical_specialty, medicine.diagnostic_test, business.industry, Fulminant, Brain biopsy, Anti-Inflammatory Agents, food and beverages, Autopsy, medicine.disease, Disease-Free Survival, Surgery, Central nervous system disease, Leukoencephalitis, Acute Hemorrhagic, Infectious Diseases, Acute Hemorrhagic Leukoencephalitis, Corticosteroid therapy, medicine, Etiology, Humans, Female, business, Child, Diagnostic radiologic examination
Abstract

Acute hemorrhagic leukoencephalitis (AHLE) is a rare, fulminant CNS demyelinating condition usually diagnosed at autopsy. We report the clinical, laboratory, radiographic, and pathologic features of the first nonfatal case of pediatric AHLE confirmed by brain biopsy. Pathologic diagnosis of this condition may be critical to exclude more-common processes and to expedite the decision to administer high-dose corticosteroid therapy, which is potentially lifesaving.

Published
2001

19. Contributors

Author

Maria Alava, M.J.G. Appel, A. Avakian, Juan Azcona-Olivera, L.A. Babiuk, Lennart Bäckström, S. Behboudi, G.P. Bembridge, Julie Brandt, R. Braun, G.P. Brooke, T. Bryan, J.L. Burton, L.E. Carmichael, A. Chapman, M.R. Chapman, R.A. Collins, Mark E. Cook, Lynette B. Corbeil, Joseph F. Curlee, Philippe Desmettre, W. Jean Dodds, Susan Duthie, P. David Eckersall, J. EkstrOm, S.A. Ellis, Inge S. Eriks, David A. Espeseth, James F. Evermann, F. Falize, R.W. Folsom, Dennis L. Foss, R.M. Gaddum, Daniel Gaudry, R. Gildersleeve, Larry T. Glickman, John R. Gorham, Kjersti Gravningen, Evan Greger, Erik Gruys, E. Haddad, George Hajishengallis, T. Harbin, Peter Heegaard, Harm HogenEsch, Susan K. Hollingshead, D.W. Horohov, Marian C. Horzinek, Margaret J. Hosie, C.J. Howard, K. Hu, Robert J. Husmann, David R. Hustead, R. Ilich, Mark W. Jackwood, Oswald Jarrett, M.E. Kehrli, S. King, T.R. Klei, Phillip H. Klesius, L.S. Kwong, E.K. Lee, J.-J. Letesson, J. Lewis, Cornelia Lipperheide, K. Lövgren-Bengtsson, M. Mackowiak, Jillian F. Maddox, Francois Madec, J. Maki, Bonnie A. Mallard, Stephen Martin, Serge Martinod, J.R. McClure, Els N.T. Meeusen, Suzanne M. Michalek, R.M. Moore, B. Morein, Paul S. Morley, W.I. Morrison, L. Motes-Kreimeyer, J.A. Mumford, L. Murray, Michael P. Murtaugh, Thomas. J. Myers, Peter L. Nara, B.J. Nonnecke, Christopher W. Olsen, Ian M. Orme, K.R. Parsons, P.P. Pastoret, P. Phelps, R. Poston, S.S. Pourciau, C.A. Ricks, James A. Roth, Michael W. Russell, Linda J. Saif, Fred W. Scott, Catharine Scott-Moncrieff, J.M. Sharma, Michael Sheppard, Craig A. Shoemaker, David Siev, Paul W. Snyder, Diane L. Sutton, C.E. Swiderski, G. Taylor, H.W. Taylor, Ian Tizard, Mathilda J.M. Toussaint, Deoki N. Tripathy, S. van den Hurk, K. Van Kampen, Jan T. van Oirschot, P. Vannier, M. Villacrés-Eriksson, Somsak Vinitnantharat, V. Weynants, C. Whitfill, Bruce N. Wilkie, C. Williams, Peter F. Wright, Hong-Yin Wu, Robert J. Yancey, and Federico A. Zuckermann

Published
1999
Full Text
View/download PDF

20. Effects of THAM and sodium bicarbonate on intracranial pressure and mean arterial pressure in an animal model of focal cerebral injury

Author

Susan Duthie, Gary D. Goulin, Mark S. Scheller, Mark H. Zornow, and Bradley M. Peterson

Subjects
Resuscitation, Mean arterial pressure, Intracranial Pressure, Bicarbonate, Blood Pressure, chemistry.chemical_compound, Tidal Volume, Medicine, Animals, Cerebral perfusion pressure, Tromethamine, Intracranial pressure, Sodium bicarbonate, business.industry, Head injury, Osmolar Concentration, Carbon Dioxide, Hydrogen-Ion Concentration, medicine.disease, Oxygen, Anesthesiology and Pain Medicine, Blood pressure, Sodium Bicarbonate, chemistry, Anesthesia, Brain Injuries, Cerebrovascular Circulation, Injections, Intravenous, Surgery, Neurology (clinical), Rabbits, Hypotension, business
Abstract

Episodes of arterial hypotension are associated with an increased mortality in head injury patients. Rapid infusion of sodium bicarbonate in such patients may cause hypotension and elevate intracranial pressure. Therefore, we examined the effects of tromethamine (THAM) versus bicarbonate on intracranial pressure and blood pressure in a model of focal cerebral injury. THAM is a buffer that in previous studies has been shown to lower intracranial pressure. After creation of a cryogenic lesion in 13 New Zealand white rabbits, equivalent infusions (15 s duration) of sodium bicarbonate and THAM (2 mEq/kg) were administered sequentially to each animal in random order. Rapid infusion was chosen to simulate the administration of these drugs during a resuscitation. THAM infusion was associated with a significantly lower intracranial pressure and blood pressure than bicarbonate. The fall in blood pressure was great enough that cerebral perfusion pressure after THAM infusion was significantly lower than after bicarbonate infusion. In this model of cerebral injury, rapid infusion of THAM offered no therapeutic advantage over bicarbonate.

Published
1994

21. THE EFFECTS OF THAM AND SODIUM BICARBONATE ON INTRACRANIAL PRESSURE AND MEAN ARTERIAL PRESSURE IN AN ANIMAL MODEL OF FOCAL CEREBRAL INJURY

Author

Gary D. Goulin, Mark H. Zornow, Bradley M. Peterson, Mark S. Scheller, and Susan Duthie

Subjects
Mean arterial pressure, Cerebral injury, chemistry.chemical_compound, Sodium bicarbonate, Animal model, chemistry, business.industry, Anesthesia, Medicine, Critical Care and Intensive Care Medicine, business, Intracranial pressure
Published
1994
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results