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Your search keyword '"Suresh T. Hedau"' showing total 4 results
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4 results on '"Suresh T. Hedau"'

1. In silico prediction and interaction of resveratrol on methyl-CpG binding proteins by molecular docking and MD simulations study

Author

Ram Krishna Sahu, Ved Vrat Verma, Amit Kumar, Simran Tandon, Bhudev Chandra Das, and Suresh T. Hedau

Subjects
endocrine system diseases, General Chemical Engineering, General Chemistry, skin and connective tissue diseases
Abstract

Resveratrol enhances the BRCA1 gene expression and the MBD family of proteins bind to the promoter region of the BRCA1 gene.

Published
2022

4. Development of a pH-sensitive functionalized metal organic framework

Author

Ragini, Singh, Binayak, Kumar, Ram Krishna, Sahu, Soni, Kumari, Chandan Bhogendra, Jha, Nahar, Singh, Rashi, Mathur, and Suresh T, Hedau

Abstract

Exploration of an efficient dual-drug based nanocarrier with high drug loading capacity, specific targeting properties, and long-term stability is highly desirable in cancer therapy. Metal-organic frameworks (MOFs) have proven to be a promising class of drug carriers due to their high porosity, crystalline properties with defined structure information, and their potential for further functionalization. To enhance the drug efficacy as well as to overcome the burst effect of drugs, here we synthesized a pH responsive folic acid (FA) and graphene oxide (GO) decorated zeolitical imidazolate frameworks-8 (GO-FA/ZIF-8), for targeted delivery of doxorubicin (DOX) and cyclophosphamide (CP), simultaneously. In this system, DOX molecules were encapsulated in the pores of ZIF-8 during

Published
2021

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