2,088 results on '"Suresh, N"'
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2. Development of a framework for enhanced collection of national health insurance levies in Ghana
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Wilson, Victor, Kumar, K. M. Sharath, and Suresh, N.
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- 2020
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3. Empirical Evaluation of the Impact of Commercial KPIs on Financial Performance of MTN Ghana Ltd
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Maka, Bismark and Suresh, N.
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- 2019
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4. Crystal growth, structural, optical, magnetic and thermal properties of pure and thiourea doped L-alanine single crystals for nonlinear optical applications
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Suresh, N., Selvapandiyan, M., Arumugam, J., and Sudhakar, S.
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- 2019
5. Enhancing Mechanical Characteristics of LM9 Aluminum Alloy by Optimization of Electromagnetic Vibration Analysis
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Thillikkani, S., Suresh, N., and Abraham, D. S. Manoj
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- 2024
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6. Design of CMOS Based LC-Voltage Control Oscillator Using Substrate Bias Effect and Current Mirror Technique
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Suresh, N., Kumar, S. Ashok, and Kamatham, Harikrishna
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- 2024
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7. Dielectric, magnetic, microwave shielding, and mechanical behavior of flexible NiFe2O4 and black gram pod biocarbon PVA composites in E, F, I, and J band frequencies
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Suresh, N., Sivakumar, P., Malathi, A. Christina Josephine, and Veeramalini, J.B.
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- 2024
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8. Review of Financial Performance analysis of Corporate Organizations
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Maka, Bismark and Suresh, N.
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- 2018
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9. Role of Process Automation in Service Quality Enhancement of MSMEs
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Suresh, N.
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- 2017
10. Organ Failure: A Computational Model and Perspective
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Periola, Ayodele A., Sesham, S., and Suresh, N.
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- 2024
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11. Outcomes of surgical revascularization for pediatric moyamoya disease and syndrome
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Boulter, Jason H., Szuflita, Nicholas S., Keating, Robert F., and Magge, Suresh N.
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- 2024
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12. Photocatalytic and bactericidal activity of zinc oxide nanoparticles biosynthesized with Datura metel leaf extract
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Akila, K., Thambidurai, S., Suresh, N., and Prabu, K. M.
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- 2024
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13. Pediatric ping-pong skull fractures treated with vacuum-assisted elevation
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Ahmed, Syed D., Allhusen, Virginia D., Muhonen, Michael G., and Magge, Suresh N.
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- 2024
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14. Preclinical assessment of MAGMAS inhibitor as a potential therapy for pediatric medulloblastoma
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Motahari, Zahra, Lepe, Javier J, Bautista, Malia R, Hoerig, Clay, Plant-Fox, Ashley S, Das, Bhaskar, Fowler, Christie D, Magge, Suresh N, and Bota, Daniela A
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Biochemistry and Cell Biology ,Biomedical and Clinical Sciences ,Biological Sciences ,Pediatric Cancer ,Rare Diseases ,Cancer ,Brain Disorders ,Brain Cancer ,Pediatric ,Orphan Drug ,Neurosciences ,5.1 Pharmaceuticals ,Medulloblastoma ,Humans ,Animals ,Mice ,Cell Proliferation ,Cell Line ,Tumor ,Cell Movement ,Xenograft Model Antitumor Assays ,Cerebellar Neoplasms ,Antineoplastic Agents ,Child ,Apoptosis ,General Science & Technology - Abstract
Medulloblastoma is the most common malignant brain tumor in children. It has WNT-driven, SHH-driven/TP53 mutant, SHH-driven/TP53 wildtype, and non-WNT/non-SHH subgroups. MAGMAS (Mitochondrial Associated Granulocyte Macrophage colony-stimulating factor Signaling molecules) encodes a mitochondrial import inner membrane translocase subunit and is responsible for the translocation of matrix proteins across the inner membrane. We previously reported that a small molecule MAGMAS inhibitor, BT9, decreases cell proliferation, migration, and oxidative phosphorylation in adult glioblastoma cell lines. The aim of our study was to investigate whether the chemotherapeutic effect of BT9 can be extended to pediatric medulloblastoma.MethodsDAOY (SHH driven/tp53 mutant) and D425 (non-SHH group 3) were treated with BT9. For in vitro analysis, cell proliferation, death, migration, invasion, and metabolic activity were assessed using MTT assay, TUNEL staining, scratch wound assay, Matrigel invasion chambers, and seahorse assay, respectively. A D425 orthotopic xenograft mouse model was used to evaluate BT9 efficacy in vivo.ResultsBT9 treatment resulted in a significant decrease in cell proliferation (DAOY, 24 hours IC50: 3.6 μM, 48 hours IC50: 2.3 μM, 72 hours IC50: 2.1 μM; D425 24 hours IC50: 3.4 μM, 48 hours IC50: 2.2 μM, 72 hours IC50: 2.1 μM) and a significant increase in cell death (DAOY, 24 hours p = 0.0004, 48 hours p
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- 2024
15. Standardisation of microencapsulation protocol for chilled preservation of Malabari buck spermatozoa
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K.K. Nivethitha, B. Bibin Becha, C. Jayakumar, K. Lekshmi Bhai, and Suresh N. Nair
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Animal biochemistry ,QP501-801 ,Science (General) ,Q1-390 - Abstract
The present study was conducted to standardise the protocol for microencapsulation of buck spermatozoa for its chilled preservation. Semen ejaculates collected from Malabari bucks of age two to three years, weighing 42 to 46 Kg and maintained under uniform managemental conditions were utilised. Sodium alginate of concentrations 0.5, 0.75 and 1.5 per cent with varying gauge sized hypodermic needles of 18G, 20G and 23G were used. The distance between the tip of the needle and the upper meniscus of BaCl2 solution was adjusted to varied distance like ≥ 7 cm, 3.5 to 5 cm, ≤ 2cm. This resulted in capsule sizes of 1 mm, 2 mm, 3 mm, 4 mm, 4.5 mm, 6 mm and 7 mm. Different shape of capsules like globular, plate like, irregular, tear-drop and oval were obtained and the capsule stability varied from 35 to 75 per cent. Capsule parameters were assessed at 0 h, 24 h, 48 h, 72 h and 96 h of chilled preservation in EYC extender at ratio of (1:2). The results of the present study cited that 1.5 per cent sodium alginate concentration, with 23G sized hypodermic needle and distance of 3.5 cm were ideal to acquire uniform spherical shaped stable capsule of size 1.90 ± 0.03 and stability of 75 per cent Keywords: Microencapsulation, chilled preservation, buck spermatozoa, Malabari
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- 2024
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16. Investigation of serum biochemical responses in White Leghorn layer birds following acute avian toxicity screening using indoxacarb
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P. U. Aswathy, Suresh N Nair, A. R. Nisha, Sanis Juliet, P Anitha, Asha Rajagopal, and I. S. Sajitha
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Animal biochemistry ,QP501-801 ,Science (General) ,Q1-390 - Abstract
The experiment was undertaken to study the effect of indoxacarb on various biochemical parameters in White Leghorn layer birds for a period of 14 days following a single oral administration. The study follows OECD guideline no. 223. White Leghorn layer birds (n=30) weighing between 1.2 to 1.6 kg were used for the study. Six birds were kept as the control group and approximately 2 ml of blood was collected in EDTA tubes on days 7 and 14 of the experiment. Biochemical parameters such as alkaline phosphatase (ALP), aspartate aminotransferase (AST), alanine aminotransferase (ALT), creatinine and blood urea nitrogen (BUN) were estimated. The mean values of ALP, AST, ALT and BUN were found significantly higher on days 7 and 14 of the acute toxicity study of indoxacarb in layers as compared to that of the control group. Keywords: Biochemical, layers, indoxacarb
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- 2024
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17. In vitro assessment of assembly and sex pheromones in the control of larval stages of brown dog ticks
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E. Hiba Basheer, Bindu Lakshmanan, M. J. Sethulekshmi, Asha Rajagopal, C.P. Athira, Suresh N Nair, M.N. Priya, and K. Devada
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Animal biochemistry ,QP501-801 ,Science (General) ,Q1-390 - Abstract
The increasing incidence of tick-borne diseases and the growing resistance to conventional acaricides underscore the urgent need for innovative and sustainable tick management strategies. This study investigates the potential of assembly and sex pheromones for the control of larval stages of Rhipicephalus sanguineus, the brown dog tick, which poses significant health risks to dogs. The ticks were collected from various canine hosts in Thrissur, Kerala and subjected to Petri-dish bioassays using vapour patches impregnated with synthetic assembly pheromone (AP) and sex pheromone (SP), both individually and in combination. The efficacy of these semiochemicals was assessed based on the attraction and clustering behaviour of unfed larvae and partially fed adult ticks over a 24-hour period. Results demonstrated a significantly higher attraction to AP-impregnated patches, with notable efficacy observed in causing tick aggregation, particularly beyond 30 min of exposure. While SP also showed potential in attracting ticks, the combination of SP and AP did not result in a synergistic effect. The study highlights the potential of using semiochemicals as an environmentally sustainable alternative to traditional acaricides, highlighting their role in integrated pest management strategies Keywords: Rhipicephalus sanguineus, adenine, guanine, xanthine, 2,6-DCP, Petri-dish bioassay
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- 2024
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18. Integrating Environmental, Social, and Governance (ESG) Factors into Social Accounting Frameworks: Implications for Sustainable Business Practices
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Suresh, N. V., Selvakumar, Ananth, Sasikala, B., Sridhar, Gajalakshmi, Appolloni, Andrea, Series Editor, Caracciolo, Francesco, Series Editor, Ding, Zhuoqi, Series Editor, Gogas, Periklis, Series Editor, Huang, Gordon, Series Editor, Nartea, Gilbert, Series Editor, Ngo, Thanh, Series Editor, Striełkowski, Wadim, Series Editor, Suresh, N. V., editor, and Buvaneswari, P. S., editor
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- 2024
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19. Does the repo rate really control inflation?
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Suresh, N.
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- 2012
20. Marker assisted selection and breeding for leaf rust resistance in coffee (Coffea arabica L.) - some recent leads
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Prakash, N. S., Muniswamy, B., Hanumantha, B. T., Sreenath, H. L., Sundaresha, Kumar, Deepak, Suresh, N., Santhosh, P., Soumya, P. R., Asha, Bhat, M., Bhat, S. S., and Jayarama
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- 2011
21. Peer-Review Statements
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Suresh, N. V., Buvaneswari, P. S., Appolloni, Andrea, Series Editor, Caracciolo, Francesco, Series Editor, Ding, Zhuoqi, Series Editor, Gogas, Periklis, Series Editor, Huang, Gordon, Series Editor, Nartea, Gilbert, Series Editor, Ngo, Thanh, Series Editor, Striełkowski, Wadim, Series Editor, Suresh, N. V., editor, and Buvaneswari, P. S., editor
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- 2024
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22. Light Microscopic Examination of the Circulating Haemocytes of two Aquatic Hemipterans Lacotrephes ruber and Sphaerodema Rusticum
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Suresh, N. and Vivekananthan, T.
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- 2009
23. Nonlinear Vibration of an Euler–Bernoulli Beam Using Variational Iteration Procedure
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Shankaranarayana, Suresh N., Chandrashekara, C. V., Chaari, Fakher, Series Editor, Gherardini, Francesco, Series Editor, Ivanov, Vitalii, Series Editor, Haddar, Mohamed, Series Editor, Cavas-Martínez, Francisco, Editorial Board Member, di Mare, Francesca, Editorial Board Member, Kwon, Young W., Editorial Board Member, Tolio, Tullio A. M., Editorial Board Member, Trojanowska, Justyna, Editorial Board Member, Schmitt, Robert, Editorial Board Member, Xu, Jinyang, Editorial Board Member, Chandrashekara, C. V., editor, Mathivanan, N. Rajesh, editor, and Hariharan, K., editor
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- 2024
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24. An Empirical Study on Empowering Women through Self Help Groups
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Suresh, N. V., Rexy, V. Arul Mary, Vijayalakshmi, Appolloni, Andrea, Series Editor, Caracciolo, Francesco, Series Editor, Ding, Zhuoqi, Series Editor, Gogas, Periklis, Series Editor, Huang, Gordon, Series Editor, Nartea, Gilbert, Series Editor, Ngo, Thanh, Series Editor, Striełkowski, Wadim, Series Editor, Rani Nimmagadda, Meena, editor, S., Catherine, editor, Challapalli, Praseeda, editor, and Sasirekha, V., editor
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- 2024
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25. Digital Healthcare and Patient Transformation: Review Research and Future Agenda
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Bhojak, Nimesh P., author, Patel, Suresh N., author, and Momin, Mohammadali K., author
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- 2023
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26. Antineoplastic activity of plant-derived compounds mediated through inhibition of histone deacetylase: a review
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Rajaselvi, N. Divya, Jida, M. D., Ajeeshkumar, K. K., Nair, Suresh N., John, Preethy, Aziz, Zarina, and Nisha, A. R.
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- 2023
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27. Haematobiochemical alterations observed in acute pancreatitis induced by L-arginine in rat
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Aravind K. Unni, K.S. Prasanna, S.S. Devi, B. Dhanush Krishna, Suresh N. Nair, A. Rajendra Prasad, R. Bharathi, and S. Sruthi
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Animal biochemistry ,QP501-801 ,Science (General) ,Q1-390 - Published
- 2024
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28. Interrogation of A Bubble in the Indian Market
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Gangadharan, Ganapathy G and Suresh, N.
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Quantitative Finance - General Finance - Abstract
Emerging markets such as India provide investors with returns far greater than those in developed markets; taking the average returns from the period 1995 to 2014 the returns are 4.714% to 3.276% of the developed market. The majority of emerging markets commenced joining with the capital market of the world, thus allowing a huge inflow of capital which in turn paved the path for economic growth. Even though the emerging markets provide high returns these may also be an indication of a bubble formation. Detection of a bubble is a tedious task primarily due to the fundamental value of the security being uncertain, and the randomness of the fundamentals of the market makes detecting bubbles an arduous task. Ratios that foretold the financial crisis of 2007- Market Capitalization to GDP, Price to Earnings Ratio, Price to Book Value, Tobins Q. Data is collected from 1999-2000 from various Indian indices such as NIFTY 50, NIFTY NEXT 50, NIFTY BANK, NIFTY 500 S and PBSE SENSEX, S and P BSE 100. The paper utilizes the ratios mentioned above to detect and backtrack various bubble episodes in the Indian market; the methodology used is the Philips et al 2015 right-tailed unit test. The paper is also inclined to take steps to mitigate the effects of a bubble by amending the financial policies and the monetary liquidity of the financial system., Comment: 7 pages, 1 figure, 1 table, published in Journal of Management
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- 2022
29. Indian Derivatives Market Evolution and Challenge
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C., Shruthi B. and Suresh, N.
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Quantitative Finance - General Finance - Abstract
The study is conducted to establish the framework for comparing the relation in performance of the derivatives of BSE and NSE in India and to analyse the relationship of derivatives with the cash market and the market volatility. The exchange-traded equity derivatives were considered for the study. It was found that the performance of derivatives in NSE is a lot higher than in BSE and the NSE is on par with the global exchanges compared to BSE in terms of the number of contracts traded for Stock Index Options and Futures and also Stock Futures. Hence derivatives market needs to strengthen further with the number of contracts traded and turnover in all the derivative instruments with more strong regulations and a robust framework protecting the interest of the investors. This study enables Derivative Industry to progress towards its goals and objectives in a more efficient way., Comment: 11 pages, 11 Graphs, Published in International Journal of Engineering and Management Research (IJEMR)
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- 2022
30. A Study on Impact of Dividend Policy on Initial Public Offering Price Performance
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Meghna, S., Suresh, N., and Usha, J. C.
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Quantitative Finance - General Finance - Abstract
This study examines the impact of dividend policy on the performance of initial public offerings in India. The period of study is from the year 2011-2014. Monthly returns of the IPOs issued in the considered period and the Indian Stock Market Index (Nifty 50) were considered for the long-run performance study. The methodological tools used are long-run performance statistics and the GARCH model. The Dummy variable was used to measure the effect of dividends on the IPOs. The study reveals that the dividend policy has no significant effect on the stock prices of IPO., Comment: 7 PAGES 6 FIGURES 6 TABLES PUBLISHED IN Journal of Engineering and Applied Sciences
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- 2022
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31. Effect of Demonetisation of on Indian High Denomination Currencies on Indian Stock Market and its Relationship with Foreign Exchange Rate
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Suresh, N. and Bharathi, N. R.
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Quantitative Finance - General Finance - Abstract
This study examines the impact of the foreign exchange rate, i.e., US Dollar to Indian Rupee (USD/INR) on the Indian Stock Market Index (Nifty 50) during the demonetization of high denomination Indian currencies. A daily rate of return of Foreign exchange rate (USD/INR) and the Indian Stock Market Index (Nifty 50) were considered for the study. The Dummy variable was used to measure the effect of demonetization during Nov/Dec 2016. The period of study was restricted to 243 days from 1st April 2016 to 31st March 2017. The study reveals that there was an upward trend observed in the Indian Stock Market and the Indian currency was strengthened with the decrease in the Foreign exchange rate (USD/INR)., Comment: 7 pages, 5 Figures, published in International Business Management in 2018
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- 2022
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32. Digital Healthcare and Patient Transformation: Review Research and Future Agenda
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Bhojak, Nimesh P., primary, Patel, Suresh N., additional, and Momin, Mohammadali K., additional
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- 2023
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33. Studies on the post cracking behaviour of Recycled Aggregate Concrete beams at elevated temperature
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Rao, Vadiraj, Suresh, N., and Arun Kumar, G.P.
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- 2023
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34. In vitro cytotoxicity of Tinospora cordifolia stem extract in Daltons Lymphoma Ascites cell lines
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O. Shyju, Bindya Liz Abraham, Suresh N. Nair, B. Dhanush Krishna, Muhasin Asaf, and T.V. Aravindakshan
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tinospora cordifolia ,cytotoxicity ,mtt assay ,trypan blue dye ,Animal biochemistry ,QP501-801 ,Science (General) ,Q1-390 - Abstract
Tinospora cordifolia (TC) is one of the most versatile medicinal plants in Ayurvedic medicine used for the treatment of various ailments. The present study was carried out to investigate the in vitro cytotoxicity of the aqueous extract of TC stems on Dalton’s lymphoma ascites (DLA) cell lines in comparison with a reference drug, cisplatin through 3-(4, 5-dimethylthiazol-2-yl)-2, 5-phenyl tetrazolium bromide assay (MTT) and Trypan blue dye exclusion methods. Phytochemical analysis of aqueous extract of TC revealed the presence of alkaloids, flavonoids, steroids, glycosides, phenols, anthraquinones, quinones, saponin, carbohydrates and proteins. The MTT assay revealed that the mean per cent inhibition of cells at the test concentrations of 5, 10, 20, 40, 80, 160, 320, 640 μg/mL ranged from 6.848 ±0.01 to 59.686 ±0.13 for TC extract and from 29.129 ±0.13 to 80.902 ±0.05 for cisplatin, respectively. The IC50values of TC and cisplatin in DLA cells were estimated to be 72.05 μg/mL and 65.44μg/mL respectively. Trypan blue dye exclusion revealed the mean per cent cell viability to be 59.40 ±0.04 and 55.17 ±0.01 for TC stem extract and cisplatin respectively. The mean percent cell viability and inhibition differed between TC extract and cisplatin at IC50 as well as at any given concentration significantly (p
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- 2023
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35. Immunomodulatory therapy in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS, MIS-C; RECOVERY): a randomised, controlled, open-label, platform trial
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Faust, Saul N, Haynes, Richard, Jones, Christine E, Staplin, Natalie, Whittaker, Elizabeth, Jaki, Thomas, Juszczak, Ed, Spata, Enti, Wan, Mandy, Bamford, Alasdair, Dimitri, Paul, Finn, Adam, Furness, John, Ramanan, Athimalaipet V, Gale, Christopher, Cathie, Katrina, Drysdale, Simon, Bernatoniene, Jolanta, Murray, Clare, Roehr, Charles C, Fleming, Paul, Riordan, Andrew, Bandi, Srini, Jyothish, Deepthi, Evans, Jennifer, Emonts, Marieke, Kelly, Dominic, Pathan, Nazima, Davies, Patrick, Hague, Rosie, Pollock, Louisa, Semple, Malcolm G, Peto, Leon, Baillie, J Kenneth, Buch, Maya, Jeffery, Katie, Knight, Marian, Lim, Wei Shen, Montgomery, Alan, Mukherjee, Aparna, Mumford, Andrew, Rowan, Kathryn, Thwaites, Guy, Mafham, Marion, Emberson, Jonathan, Landray, Martin J, Horby, Peter W, Chappell, Lucy, Day, Jeremy, Dung, DV, Quang, NN, Binh, Prof, Burhan, E, Alisjahbana, B, Koirala, J, Basnet, S, Kestelyn, E, Basnyat, B, Gyanwali, P, Hamers, RL, Sandercock, P, Darbyshire, J, DeMets, D, Fowler, R, Lalloo, D, Munavvar, M, Roberts, I, Warris, A, Wittes, J, Craddock-Bamford, A, Barton, J, Basoglu, A, Brown, R, Brudlo, W, Denis, E, Fletcher, L, Howard, S, Musini, S, Taylor, K, Cui, G, Goodenough, B, King, A, Lay, M, Murray, D, Stevens, W, Wallendszus, K, Welsh, R, Crichton, C, Davies, J, Goldacre, R, Harper, C, Knight, F, Nunn, M, Salih, H, Welch, J, Campbell, M, Pessoa-Amorim, G, Zayed, M, Wiles, J, Bagley, G, Cameron, S, Chamberlain, S, Farrell, B, Freeman, H, Kennedy, A, Whitehouse, A, Wilkinson, S, Wood, C, Reith, C, Davies, K, Halls, H, Holland, L, Truell, R, Wilson, K, Lingwood, Emma, Howie, L, Lunn, M, Rodgers, Penelope, Amuasi, J, Baird, K, Bao, T, Bittaye, M, Bonney, J, D'Alessandro, U, Dhimal, M, Huyen, T, Jagne, A, Karkey, A, Maiga, O, Matey, E, Nadjm, B, Nel, J, Pant, S, Puspatriani, K, Rahardjani, M, Raijal, S, Rees, H, Rimainar, A, Roberts, C, Rocca, A, Shrestha, S, Usuf, E, Vidaillic, C, Wulandari, F, Alexander, A, Amezaga, M, Armah, C, Asghar, A, Aubrey, P, Barker-Williams, K, Barnard, A, Bartholomew, J, Beaumont-Jewell, D, Beddows, S, Beety, J, Birch, C, Boyle, P, Brend, M, Brookes, M, Callens, C, Campbell, D, Campbell, H, Cate, H, Chambers, E, Chapman, K, Coe, A, Collins, J, Crawshaw, S, Das, S, De Soyza, A, Denton, E, Dicks, P, Dolman, M, Donaldson, K, Dowden, L, Dowling, S, Drake, C, Duckles-Leech, H, Duffy, H, Gerdes, L, Gibbons, K, Gill, L, Gilmour, K, Goodwin, J, Graham, J, Green, C, Hall, C, Hall, A, Hampshire, K, Hanson, J, Harman, T, Harper, H, Harrison, S, Hicks, J, Hodgson, H, Hough, M, Jackson, S, Johnson, G, Kirk, J, Lemoine, N, Levett, C, Lock, S, Lockett, T, Logan, M, Lomme, K, Luo, J, McMillan, N, Membrey, H, Mguni, N, Minton, J, Monaghan, H, Murphy, S, Muzengi, N, Naz, M, Nickson, I, Odam, M, Ohia, U, Okell, E, Oliver, A, Pearson, K, Pine, K, Pleass, R, Porter, D, Porter, L, Potter, A, Poustie, V, Pratt, S, Price, A, Priest, A, Rodgers, A, Rook, C, Ryan, P, Sam, S, Sharratt, P, Sheffield, J, Shenton, J, Shirley, K, Skinner, T, Slade, H, Sutu, M, Taylor, J, Thomas, E, Tinkler, H, Unsworth, A, Usher, R, van't Hoff, W, Walker, S, Walters, J, Walton, E, Warmington, J, Wayman, E, Williams, P, Williamson, J, Williamson, D, Yelnoorkar, F, Knight, M, Hodson, K, Pavord, S, Williamson, C, Bowman, L, Chen, F, Clarke, R, Goonasekara, M, Herrington, W, Judge, P, Ng, S, Preiss, D, Sammons, E, Zhu, D, Arkley, C, Bowker, P, Bruce, J, Byrne-Watts, V, Chapman, G, Coleman, G, Denwood, T, Gray, J, Harrison, D, Mather, N, Pinches, H, Rees, A, Rees, S, Turner, G, Abani, O, Abbas, A, Abbas, F, Abbas, J, Abbas, K, Abbas, M, Abbasi, S, Abbass, H, Abbott, A, Abdallah, N, Abdelaziz, A, Abdelfattah, M, Abdelqader, B, Abdul, A, Abdul, B, Abdul, S, Abdul Rasheed, A, Abdulakeem, A, Abdul-Kadir, R, Abdullah, A, Abdulmumeen, A, Abdul-Raheem, R, Abdulshukkoor, N, Abdusamad, K, Abed El Khaleq, Y, Abedalla, M, Abeer Ul Amna, A, Abel, L, Abernethy, K, Abeywickrema, M, Abhinaya, C, Aboaba, A, Aboagye-Odei, A, Aboelela, H, Abo-Leyah, H, Abouelela, K, Abou-Haggar, A, Abouibrahim, M, Abousamra, A, Abouzaid, M, Abraham, M, Abraham, T, Abraheem, A, Abrams, J, Abrams, R, Abu, H, Abu-Arafeh, A, Abubacker, S, Abung, A, Abusamra, Y, Aceampong, Y, Achara, A, Acharya, D, Acheampong, S, Acheampong, P, Acheson, J, Achieng, S, Acosta, A, Acquah, R, Acton, C, Adabie-Ankrah, J, Adair, P, Adam, F, Adam, M, Adamali, H, Adamczyk, M, Adams, C, Adams, D, Adams, K, Adams, L, Adams, N, Adams, R, Adams, T, Adamu-Ikeme, L, Adati, K, Adcock, K, Addo, A, Adeagbo, O, Adebiyi, A, Adedeji, O, Adegeye, Y, Adegoke, K, Adell, V, Adenwalla, S, Adeoye, F, Adesemoye, O, Adewunmi, E, Adeyanju, A, Adeyemi, J, Adeyemo, T, Adhikary, R, Aditya, A, Adkins, G, Adnan, A, Aeron-Thomas, J, Affleck, D, Afnan, C, Afridi, M, Aftab, Z, Agarwal, M, Agbeko, R, Agbo, C, Aggarwal, S, Aghababaie, A, Aguilar Jimenez, L, Ahamed Sadiq, S, Ahammed Nazeer, M, Ahmed, A, Ahmed, B, Ahmed, F, Ahmed, H, Ahmed, I, Ahmed, K, Ahmed, L, Ahmad, M, Ahmed, N, Ahmed, O, Ahmed, R, 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Zulaikha, R, Zulfikar, S, Zullo, C, and Zuriaga-Alvaro, A
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- 2024
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36. Seismic Response of Coupled Structure, Equipment and Piping System with and Without Base Isolation—An Experiment
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Reddy, G. R., Sajish, S. D., Ravikiran, A., Preetha, R., Singh, Tarvinder, Mohanraj, P., Verma, R. K., Mohanraj, K. V., Parmar, R. M., Rajesh, S. K., Mahesh Kumar, R., Suresh, N., Deb, S. K., di Prisco, Marco, Series Editor, Chen, Sheng-Hong, Series Editor, Vayas, Ioannis, Series Editor, Kumar Shukla, Sanjay, Series Editor, Sharma, Anuj, Series Editor, Kumar, Nagesh, Series Editor, Wang, Chien Ming, Series Editor, Shrikhande, Manish, editor, Agarwal, Pankaj, editor, and Kumar, P. C. Ashwin, editor
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- 2023
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37. Analytical Studies on the Fire Resistance of Reinforced Concrete Beams Exposed to Parametric Time–Temperature Curve
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Amar Hebbar, V. P., Sachin, V., Suresh, N., di Prisco, Marco, Series Editor, Chen, Sheng-Hong, Series Editor, Vayas, Ioannis, Series Editor, Kumar Shukla, Sanjay, Series Editor, Sharma, Anuj, Series Editor, Kumar, Nagesh, Series Editor, Wang, Chien Ming, Series Editor, Shukla, Sanjay Kumar, editor, Raman, Sudharshan N., editor, Bhattacharjee, B., editor, and Singh, Priyanka, editor
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- 2023
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38. Multiclass Discriminator for Blind Steganalysis Using Statistical Features of Digital Images
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Suryawanshi, Govind, Mali, Suresh N., Patil, Pramod D., Kacprzyk, Janusz, Series Editor, Gomide, Fernando, Advisory Editor, Kaynak, Okyay, Advisory Editor, Liu, Derong, Advisory Editor, Pedrycz, Witold, Advisory Editor, Polycarpou, Marios M., Advisory Editor, Rudas, Imre J., Advisory Editor, Wang, Jun, Advisory Editor, Senjyu, Tomonobu, editor, So–In, Chakchai, editor, and Joshi, Amit, editor
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- 2023
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39. Effects of gene replacement therapy with resamirigene bilparvovec (AT132) on skeletal muscle pathology in X-linked myotubular myopathy: results from a substudy of the ASPIRO open-label clinical trial
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Lawlor, Michael W., Schoser, Benedikt, Margeta, Marta, Sewry, Caroline A., Jones, Karra A., Shieh, Perry B., Kuntz, Nancy L., Smith, Barbara K., Dowling, James J., Müller-Felber, Wolfgang, Bönnemann, Carsten G., Seferian, Andreea M., Blaschek, Astrid, Neuhaus, Sarah, Foley, A. Reghan, Saade, Dimah N., Tsuchiya, Etsuko, Qasim, Ummulwara R., Beatka, Margaret, Prom, Mariah J., Ott, Emily, Danielson, Susan, Krakau, Paul, Kumar, Suresh N., Meng, Hui, Vanden Avond, Mark, Wells, Clive, Gordish-Dressman, Heather, Beggs, Alan H., Christensen, Sarah, Conner, Edward, James, Emma S., Lee, Jun, Sadhu, Chanchal, Miller, Weston, Sepulveda, Bryan, Varfaj, Fatbardha, Prasad, Suyash, and Rico, Salvador
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- 2024
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40. Impact of primary kidney disease on the effects of empagliflozin in patients with chronic kidney disease: secondary analyses of the EMPA-KIDNEY trial
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41. Effects of empagliflozin on progression of chronic kidney disease: a prespecified secondary analysis from the empa-kidney trial
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Staplin, N, Haynes, R, Judge, PK, Wanner, C, Green, JB, Emberson, J, Preiss, D, Mayne, KJ, Ng, SYA, Sammons, E, Zhu, D, Hill, M, Stevens, W, Wallendszus, K, Brenner, S, Cheung, AK, Liu, ZH, Li, J, Hooi, LS, Liu, WJ, Kadowaki, T, Nangaku, M, Levin, A, Cherney, D, Maggioni, AP, Pontremoli, R, Deo, R, Goto, S, Rossello, X, Tuttle, KR, Steubl, D, Petrini, M, Seidi, S, Landray, MJ, Baigent, C, Herrington, WG, Abat, S, Abd Rahman, R, Abdul Cader, R, Abdul Hafidz, MI, Abdul Wahab, MZ, Abdullah, NK, Abdul-Samad, T, Abe, M, Abraham, N, Acheampong, S, Achiri, P, Acosta, JA, Adeleke, A, Adell, V, Adewuyi-Dalton, R, Adnan, N, Africano, A, Agharazii, M, Aguilar, F, Aguilera, A, Ahmad, M, Ahmad, MK, Ahmad, NA, Ahmad, NH, Ahmad, NI, Ahmad Miswan, N, Ahmad Rosdi, H, Ahmed, I, Ahmed, S, Aiello, J, Aitken, A, AitSadi, R, Aker, S, Akimoto, S, Akinfolarin, A, Akram, S, Alberici, F, Albert, C, Aldrich, L, Alegata, M, Alexander, L, Alfaress, S, Alhadj Ali, M, Ali, A, Alicic, R, Aliu, A, Almaraz, R, 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M, Nishi, S, Nishida, Y, Nishiyama, A, Niu, J, Niu, P, Nobili, G, Nohara, N, Nojima, I, Nolan, J, Nosseir, H, Nozawa, M, Nunn, M, Nunokawa, S, Oda, M, Oe, M, Oe, Y, Ogane, K, Ogawa, W, Ogihara, T, Oguchi, G, Ohsugi, M, Oishi, K, Okada, Y, Okajyo, J, Okamoto, S, Okamura, K, Olufuwa, O, Oluyombo, R, Omata, A, Omori, Y, Ong, LM, Ong, YC, Onyema, J, Oomatia, A, Oommen, A, Oremus, R, Orimo, Y, Ortalda, V, Osaki, Y, Osawa, Y, Osmond Foster, J, O'Sullivan, A, Otani, T, Othman, N, Otomo, S, O'Toole, J, Owen, L, Ozawa, T, Padiyar, A, Page, N, Pajak, S, Paliege, A, Pandey, A, Pandey, R, Pariani, H, Park, J, Parrigon, M, Passauer, J, Patecki, M, Patel, M, Patel, R, Patel, T, Patel, Z, Paul, R, Paulsen, L, Pavone, L, Peixoto, A, Peji, J, Peng, BC, Peng, K, Pennino, L, Pereira, E, Perez, E, Pergola, P, Pesce, F, Pessolano, G, Petchey, W, Petr, EJ, Pfab, T, Phelan, P, Phillips, R, Phillips, T, Phipps, M, Piccinni, G, Pickett, T, Pickworth, S, Piemontese, M, Pinto, D, Piper, J, Plummer-Morgan, J, 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Simmons, K, Sinha, S, Sitter, T, Sivanandam, S, Skipper, M, Sloan, K, Sloan, L, Smith, R, Smyth, J, Sobande, T, Sobata, M, Somalanka, S, Song, X, Sonntag, F, Sood, B, Sor, SY, Soufer, J, Sparks, H, Spatoliatore, G, Spinola, T, Squyres, S, Srivastava, A, Stanfield, J, Staylor, K, Steele, A, Steen, O, Steffl, D, Stegbauer, J, Stellbrink, C, Stellbrink, E, Stevenson, A, Stewart-Ray, V, Stickley, J, Stoffler, D, Stratmann, B, Streitenberger, S, Strutz, F, Stubbs, J, Stumpf, J, Suazo, N, Suchinda, P, Suckling, R, Sudin, A, Sugamori, K, Sugawara, H, Sugawara, K, Sugimoto, D, Sugiyama, H, Sugiyama, T, Sullivan, M, Sumi, M, Suresh, N, Sutton, D, Suzuki, H, Suzuki, R, Suzuki, Y, Swanson, E, Swift, P, Syed, S, Szerlip, H, Taal, M, Taddeo, M, Tailor, C, Tajima, K, Takagi, M, Takahashi, K, Takahashi, M, Takahashi, T, Takahira, E, Takai, T, Takaoka, M, Takeoka, J, Takesada, A, Takezawa, M, Talbot, M, Taliercio, J, Talsania, T, Tamori, Y, Tamura, R, Tamura, Y, Tan, CHH, Tan, EZZ, Tanabe, A, Tanabe, K, Tanaka, A, Tanaka, N, Tang, S, Tang, Z, Tanigaki, K, Tarlac, M, Tatsuzawa, A, Tay, JF, Tay, LL, Taylor, J, Taylor, K, Te, A, Tenbusch, L, Teng, KS, Terakawa, A, Terry, J, Tham, ZD, Tholl, S, Thomas, G, Thong, KM, Tietjen, D, Timadjer, A, Tindall, H, Tipper, S, Tobin, K, Toda, N, Tokuyama, A, Tolibas, M, Tomita, A, Tomita, T, Tomlinson, J, Tonks, L, Topf, J, Topping, S, Torp, A, Torres, A, Totaro, F, Toth, P, Toyonaga, Y, Tripodi, F, Trivedi, K, Tropman, E, Tschope, D, Tse, J, Tsuji, K, Tsunekawa, S, Tsunoda, R, Tucky, B, Tufail, S, Tuffaha, A, Turan, E, Turner, H, Turner, J, Turner, M, Tye, YL, Tyler, A, Tyler, J, Uchi, H, Uchida, H, Uchida, T, Udagawa, T, Ueda, S, Ueda, Y, Ueki, K, Ugni, S, Ugwu, E, Umeno, R, Unekawa, C, Uozumi, K, Urquia, K, Valleteau, A, Valletta, C, van Erp, R, Vanhoy, C, Varad, V, Varma, R, Varughese, A, Vasquez, P, Vasseur, A, Veelken, R, Velagapudi, C, Verdel, K, Vettoretti, S, Vezzoli, G, Vielhauer, V, Viera, R, Vilar, E, Villaruel, S, Vinall, L, Vinathan, J, Visnjic, M, Voigt, E, von-Eynatten, M, Vourvou, M, Wada, J, Wada, T, Wada, Y, Wakayama, K, Wakita, Y, Walters, T, Wan Mohamad, WH, Wang, L, Wang, W, Wang, X, Wang, Y, Wanninayake, S, Watada, H, Watanabe, K, Watanabe, M, Waterfall, H, Watkins, D, Watson, S, Weaving, L, Weber, B, Webley, Y, Webster, A, Webster, M, Weetman, M, Wei, W, Weihprecht, H, Weiland, L, Weinmann-Menke, J, Weinreich, T, Wendt, R, Weng, Y, Whalen, M, Whalley, G, Wheatley, R, Wheeler, A, Wheeler, J, Whelton, P, White, K, Whitmore, B, Whittaker, S, Wiebel, J, Wiley, J, Wilkinson, L, Willett, M, Williams, A, Williams, E, Williams, K, Williams, T, Wilson, A, Wilson, P, Wincott, L, Wines, E, Winkelmann, B, Winkler, M, Winter-Goodwin, B, Witczak, J, Wittes, J, Wittmann, M, Wolf, G, Wolf, L, Wolfling, R, Wong, C, Wong, E, Wong, HS, Wong, LW, Wong, YH, Wonnacott, A, Wood, A, Wood, L, Woodhouse, H, Wooding, N, Woodman, A, Wren, K, Wu, J, Wu, P, Xia, S, Xiao, H, Xiao, X, Xie, Y, Xu, C, Xu, Y, Xue, H, Yahaya, H, Yalamanchili, H, Yamada, A, Yamada, N, Yamagata, K, Yamaguchi, M, Yamaji, Y, Yamamoto, A, Yamamoto, S, Yamamoto, T, Yamanaka, A, Yamano, T, Yamanouchi, Y, Yamasaki, N, Yamasaki, Y, Yamashita, C, Yamauchi, T, Yan, Q, Yanagisawa, E, Yang, F, Yang, L, Yano, S, Yao, S, Yao, Y, Yarlagadda, S, Yasuda, Y, Yiu, V, Yokoyama, T, Yoshida, S, Yoshidome, E, Yoshikawa, H, Young, A, Young, T, Yousif, V, Yu, H, Yu, Y, Yuasa, K, Yusof, N, Zalunardo, N, Zander, B, Zani, R, Zappulo, F, Zayed, M, Zemann, B, Zettergren, P, Zhang, H, Zhang, L, Zhang, N, Zhang, X, Zhao, J, Zhao, L, Zhao, S, Zhao, Z, Zhong, H, Zhou, N, Zhou, S, Zhu, L, Zhu, S, Zietz, M, Zippo, M, Zirino, F, and Zulkipli, FH
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- 2024
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42. Evaluation of electrocardiographic and serum biochemical changes in arrhythmias associated with renal diseases of dogs
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U. S. Remya Krishna, Arun George, Usha Narayana Pillai, Sindhu K. Rajan, and Suresh N. Nair
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renal disease ,arrhythmia ,electrocardiography ,correlation studies ,Animal biochemistry ,QP501-801 ,Science (General) ,Q1-390 - Abstract
The present study was conducted to investigate electrocardiographical (ECG) and haemato-biochemical changes in arrhythmia associated with renal diseases in dogs. The dogs with renal affections confirmed through appropriate diagnostic methods were selected and screened for arrhythmia. The ECG and haemato-biochemical parameters of twenty dogs with arrhythmia were compared with that of the control group and ECG parameters were statistically correlated with the haemato-biochemical parameters for correlation studies. It was found that the occurrence of arrhythmia was 51.2 per cent in renal diseases. Arrhythmia was more predominant in dogs with chronic kidney disease (CKD) followed by acute kidney injury (AKI). Sinus arrhythmia followed by first-degree AV block and wandering pacemaker were the common types of arrhythmias observed. A significant increase in R-R interval and a decrease in heart rate was noticed in comparison. The haemato-biochemical analysis revealed anaemia, leukocytosis with neutrophilia, elevated blood urea nitrogen (BUN), creatinine and magnesium level. A significant positive correlation was noticed between haemoglobin, volume of packed red cells (VPRC) and red blood cell count (RBC) with T amplitude and, creatinine and BUN levels with corrected Q-T interval. A significant negative correlation was noticed between VPRC, RBC and haemoglobin with the corrected QT interval. The present study revealed ECG and haemato-biochemical parameters had a significant role in renal diseases in dogs which might help in the early diagnosis and proper management of arrhythmia associated with renal diseases.
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- 2023
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43. Preclinical assessment of MAGMAS inhibitor as a potential therapy for pediatric medulloblastoma.
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Zahra Motahari, Javier J Lepe, Malia R Bautista, Clay Hoerig, Ashley S Plant-Fox, Bhaskar Das, Christie D Fowler, Suresh N Magge, and Daniela A Bota
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Medicine ,Science - Abstract
Medulloblastoma is the most common malignant brain tumor in children. It has WNT-driven, SHH-driven/TP53 mutant, SHH-driven/TP53 wildtype, and non-WNT/non-SHH subgroups. MAGMAS (Mitochondrial Associated Granulocyte Macrophage colony-stimulating factor Signaling molecules) encodes a mitochondrial import inner membrane translocase subunit and is responsible for the translocation of matrix proteins across the inner membrane. We previously reported that a small molecule MAGMAS inhibitor, BT9, decreases cell proliferation, migration, and oxidative phosphorylation in adult glioblastoma cell lines. The aim of our study was to investigate whether the chemotherapeutic effect of BT9 can be extended to pediatric medulloblastoma.MethodsDAOY (SHH driven/tp53 mutant) and D425 (non-SHH group 3) were treated with BT9. For in vitro analysis, cell proliferation, death, migration, invasion, and metabolic activity were assessed using MTT assay, TUNEL staining, scratch wound assay, Matrigel invasion chambers, and seahorse assay, respectively. A D425 orthotopic xenograft mouse model was used to evaluate BT9 efficacy in vivo.ResultsBT9 treatment resulted in a significant decrease in cell proliferation (DAOY, 24 hours IC50: 3.6 μM, 48 hours IC50: 2.3 μM, 72 hours IC50: 2.1 μM; D425 24 hours IC50: 3.4 μM, 48 hours IC50: 2.2 μM, 72 hours IC50: 2.1 μM) and a significant increase in cell death (DAOY, 24 hours p = 0.0004, 48 hours pConclusionsOur in vitro data showed BT9 antitumor efficacy in DAOY and D425 cell lines, suggesting that BT9 may represent a promising targeted therapeutic in pediatric medulloblastoma. These data, however, need to be further validated in animal models.
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- 2024
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44. Synthesis, molecular structure, experimental and theoretical characterization of 3-((2-(2,4-dinitrophenyl) hydrazone) methyl) pyridine- Carcinopreventive activity (in silico and in vitro investigation)
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Vedhapriya, K., Balaji, G., Dhiyaneshwari, B., Kumaran, S., Narayana, B., Kodlady, Suresh N, Kadaikunnan, Shine, Abbas, Ghulam, and Muthu, S.
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- 2023
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45. Empagliflozin in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial
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Abani, O, Abbas, A, Abbas, F, Abbas, J, Abbas, K, Abbas, M, Abbasi, S, Abbass, H, Abbott, A, Abdallah, N, Abdelaziz, A, Abdelfattah, M, Abdelqader, B, Abdul, A, Abdul, B, Abdul, S, Abdul Rasheed, A, Abdulakeem, A, Abdul-Kadir, R, Abdullah, A, Abdulmumeen, A, Abdul-Raheem, R, Abdulshukkoor, N, Abdusamad, K, Abed El Khaleq, Y, Abedalla, M, Abeer Ul Amna, A, Abel, L, Abernethy, K, Abeywickrema, M, Abhinaya, C, Abidin, A, Aboaba, A, Aboagye-Odei, A, Aboah, C, Aboelela, H, Abo-Leyah, H, Abouelela, K, Abou-Haggar, A, Abouibrahim, M, Abousamra, A, Abouzaid, M, Abraham, M, Abraham, T, Abraheem, A, Abrams, J, Abrams, R, Abu, HJ, Abu-Arafeh, A, Abubacker, SM, Abung, A, Abusamra, Y, Aceampong, Y, Achara, A, Acharya, D, Acheampong, F, Acheampong, P, Acheampong, S, Acheson, J, Achieng, S, Acosta, A, Acquah, R, Acton, C, Adabie-Ankrah, J, Adair, P, Adam, AS, Adam, F, Adam, M, Adamali, H, Adamczyk, M, Adams, C, Adams, D, Adams, K, Adams, L, Adams, N, Adams, R, Adams, T, Adamu-Ikeme, L, Adatia, K, 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- 2023
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46. Model-free measurements of calorific content and ash content of mixed garden wastes using a bomb calorimeter
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Trombley, Jeremy B., Wang, Chun, and Thennadil, Suresh N.
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- 2023
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47. Synthesis, DFT, solvent effect and biological attributes of NLO active 4-bromo-2-((2-(2,4-Dinitrophenyl) hydrazono)methyl) phenol -Potent drug anti-brain cancer
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Cheerlin Mishma, J.N., Bena Jothy, V., Narayana, B., Kodlady, Suresh N, Alharbi, Naiyf S., Abbas, Ghulam, and Muthu, S.
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- 2023
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48. A cyclophosphamide-induced immunosuppression Swiss Albino mouse model unveils a potential role for cow urine distillate as a feed additive
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Kolathingal-Thodika, Naseema, Usha, P.T.A., Sujarani, S., Suresh, N. Nair, Priya, P.M., Naseef, Punnoth Poonkuzhi, Kuruniyan, Mohamed Saheer, Ollakkode, Shyju, and Elayadeth-Meethal, Muhammed
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- 2023
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49. No more bull: pediatric head injuries as a result of mechanical bull rides
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Xu, Jordan C., Vargas, Anthony J., Waunch, Amy, Gibbs, David L., Cappon, James P., Loudon, William G., and Magge, Suresh N.
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- 2023
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50. Exploring the benefits of in-diet versus repeated oral dosing of saracatinib (AZD0530) in chronic studies: insights into pharmacokinetics and animal welfare
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Suraj S. Vasanthi, Nyzil Massey, Suresh N. Nair, Jonathan P. Mochel, Lucas Showman, and Thimmasettappa Thippeswamy
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saracatinib ,Src tyrosine kinases ,serum ,LC–MS/MS ,hippocampus ,pharmacokinetics ,Veterinary medicine ,SF600-1100 - Abstract
Saracatinib/AZD0530 (SAR), a Src tyrosine kinase inhibitor, mitigates seizure-induced brain pathology in epilepsy models upon repeated oral dosing. However, repeated dosing is stressful and can be challenging in some seizing animals. To overcome this issue, we have incorporated SAR-in-Diet and compared serum pharmacokinetics (PK) and brain concentrations with conventional repeated oral dosing. Saracatinib in solution or in-diet was stable at room temperature for >4 weeks (97 ± 1.56%). Adult Sprague Dawley rats on SAR-in-Diet consumed ~1.7 g/day less compared to regular diet (16.82 ± 0.6 vs. 18.50 ± 0.5 g/day), but the weight gain/day was unaffected (2.63 ± 0.5 g/day vs. 2.83 ± 0.2 g/day). Importantly, we achieved the anticipated SAR dose range from 2.5–18.7 mg/kg of rat in response to varying concentrations of SAR-in-Diet from 54 to 260 ppm of feed, respectively. There was a strong and significant correlation between SAR-in-Diet dose (mg/kg) and serum saracatinib concentrations (ng/ml). Serum concentrations also did not vary significantly between SAR-in-Diet and repeated oral dosing. The hippocampal saracatinib concentrations derived from SAR-in-Diet treatment were higher than those derived after repeated oral dosing (day 3, 546.8 ± 219.7 ng/g vs. 238.6 ± 143 ng/g; day 7, 300.7 ± 43.4 ng/g vs. 271.1 ± 62.33 ng/g). Saracatinib stability at room temperature and high serum and hippocampal concentrations in animals fed on SAR-in-Diet are useful to titer the saracatinib dose for future animal disease models. Overall, test drugs in the diet is an experimental approach that addresses issues related to handling stress-induced variables in animal experiments.
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- 2023
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