8,270 results on '"Supuran, Claudiu T."'
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2. ANTIBACTERIAL Zn(II) COMPOUNDS OF. SCHIFF BASES DERIVED FROM SOME BENZOTHIAZOLES
3. Paraoxonases
4. Bacterial zinc proteases
5. Carbonic anhydrases
6. Preface
7. Introduction to metalloenzymes: From bench to bedside
8. INHIBITION OF CARBONIC ANHYDRASE ISOZYMES I, II AND IV WITH ARSINOLIPIDS
9. Novel benzenesulfonamide-aroylhydrazone conjugates as carbonic anhydrase inhibitors that induce MAPK/ERK-mediated cell cycle arrest and mitochondrial-associated apoptosis in MCF-7 breast cancer cells
10. Phosphorylation strongly affects the inhibition of human carbonic anhydrase I CO2 hydration activity
11. Exploration of 1,3,5-trisubstituted pyrazoline derivatives as human carbonic anhydrase inhibitors: Synthesis, biological evaluation and in silico studies
12. Discovery of new sulfonamide-tethered 2-aryl-4-anilinoquinazolines as the first-in-class dual carbonic anhydrase and EGFR inhibitors
13. Mitigating the resistance of MCF-7 cancer cells to Doxorubicin under hypoxic conditions with novel coumarin based carbonic anhydrase IX and XII inhibitors
14. Development of novel organometallic sulfonamides with N-ethyl or N-methyl benzenesulfonamide units as potential human carbonic anhydrase I, II, IX and XII isoforms' inhibitors: Synthesis, biological evaluation and docking studies
15. Physiological modeling of the metaverse of the Mycobacterium tuberculosis β-CA inhibition mechanism
16. INHIBITION OF CARBONIC ANHYDRASE ISOZYMES I, II AND IV WITH ARSANILIC ACID DERIVATIVES
17. Glucoimines incorporating classical and non-classical carbonic anhydrase pharmacophores: Design, synthesis, conformational analysis, biological evaluation, and docking simulations
18. INTERACTION OF ISOZYMES I AND II OF CARBONIC ANHYDRASE WITH Ge(IV) AND Sb(lll) DERIVATIVES
19. SYNTHESIS AND CARBONIC ANHYDRASE INHIBITORY ACTIVITY OF 5-BENZOYLAMIDO- AND 5-(3-NITROBENZOYLAMIDO)- 1,3,4-THIADIAZOLE-2-SULFONAMIDE AND THEIR METAL COMPLEXES
20. GERMYL AMINES AND GERMANOLS INHIBIT CARBONIC ANHYDRASE ISOZYME II BUT NOT ISOZYME I
21. INHIBITION OF CARBONIC ANHYDRASE ISOZYMES I AND II WITH THIOPHOSPHORYLIC COMPOUNDS CONTAINING 4-CARBOXYBENZENE-SULFONAMIDO MOIETIES
22. COMPLEXES WITH BIOLOGICALLY ACTIVE LIGANDS. Part 5. Zn(ll) AND Cd(ll) COORDINATION COMPOUNDS OF HYDRAZINE AND HETEROCYCLIC SULFONAMIDES AS INHIBITORS OF THE ZINC ENZYME CARBONIC ANHYDRASE
23. COMPLEXES WITH BIOLOGICALLY ACTIVE LIGANDS. Part 3 SYNTHESIS OF COORDINATION COMPOUNDS OF CHLOROTHIAZIDE WITH DIVALENT METAL IONS
24. Exploring the binding mode of phenyl and vinyl boronic acids to human carbonic anhydrases
25. Synthesis and investigation of selective human carbonic anhydrase IX, XII inhibitors using coumarins bearing a sulfonamide or biotin moiety
26. Bacterial Ectonucleotidases: Underexplored Antibacterial Drug Targets
27. CD73 Inhibitors as Antitumor Agents
28. A new framework for novel analogues of pazopanib as potent and selective human carbonic anhydrase inhibitors: Design, repurposing rational, synthesis, crystallographic, in vivo and in vitro biological assessments
29. Novel sulfonamide-tethered Schiff bases as anti-proliferative agents with VEGFR-2 inhibitory activity: Synthesis, biological assessment, and molecular dynamic simulations
30. Comparative CO2 and SiO2 hydratase activity of an enzyme from the siliceous demosponge Suberitesdomuncula
31. Carbonic anhydrase IX: An atypical target for innovative therapies in cancer
32. 2-Substituted-4,7-dihydro-4-ethylpyrazolo[1,5-a]pyrimidin-7-ones alleviate LPS-induced inflammation by modulating cell metabolism via CD73 upon macrophage polarization
33. Discovery of a new potent oxindole multi-kinase inhibitor among a series of designed 3-alkenyl-oxindoles with ancillary carbonic anhydrase inhibitory activity as antiproliferative agents
34. Probing benzenesulfonamide–thiazolidinone hybrids as multitarget directed ligands for efficient control of type 2 diabetes mellitus through targeting the enzymes: α-glucosidase and carbonic anhydrase II
35. Design, synthesis and in vitro evaluation of novel thiazole-coumarin hybrids as selective and potent human carbonic anhydrase IX and XII inhibitors
36. An asiatic acid derived trisulfamate acts as a nanomolar inhibitor of human carbonic anhydrase VA
37. A comparative study of diaryl urea molecules with and without sulfonamide group on Carbonic anhydrase IX and XII inhibition and its consequence on breast cancer cells
38. Coumarins-lipophilic cations conjugates: Efficient mitocans targeting carbonic anhydrases
39. Tumor associated carbonic anhydrase inhibitors: Rational approaches, design strategies, structure activity relationship and mechanistic insights
40. Direct assembly of N-sulfamoyl lactam scaffolds bearing a zinc-binding group for inhibiting metalloenzymes based on desymmetrization of sulfamide and the Castagnoli-Cushman reaction
41. Identification of thienopyrimidine derivatives tethered with sulfonamide and other moieties as carbonic anhydrase inhibitors: Design, synthesis and anti-proliferative activity
42. Novel 2-(hydrazinocarbonyl)-3-phenyl-1H-indole-5-sulfonamide based thiosemicarbazides as potent and selective inhibitors of tumor-associated human carbonic anhydrase IX and XII: Synthesis, cytotoxicity, and molecular modelling studies
43. Boron-containing carbonic anhydrases inhibitors
44. mGluR5 PAMs rescue cortical and behavioural defects in a mouse model of CDKL5 deficiency disorder
45. Design, synthesis, and carbonic anhydrase inhibition activities of Schiff bases incorporating benzenesulfonamide scaffold: Molecular docking application
46. Chagas Disease: Drug Development and Parasite Targets
47. Targeting Carbonic Anhydrases from Trypanosoma cruzi and Leishmania spp. as a Therapeutic Strategy to Obtain New Antiprotozoal Drugs
48. Challenges and Promises for Obtaining New Antiprotozoal Drugs: What’s Going Wrong?
49. η-Class Carbonic Anhydrases as Antiplasmodial Drug Targets: Current State of the Art and Hurdles to Develop New Antimalarials
50. Beta-Carbonic Anhydrase 1 from Trichomonas Vaginalis as New Antiprotozoan Drug Target
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