1,338 results on '"Superti-Furga, Giulio"'
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2. Ex vivo imaging-based high content phenotyping of patients with rheumatoid arthritis
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3. Image-based quantification of mitochondrial iron uptake via Mitoferrin-2
4. AspSnFR: A genetically encoded biosensor for real-time monitoring of aspartate in live cells
5. Protein Binder Toolbox for Studies of Solute Carrier Transporters
6. Development of a live cell assay for the zinc transporter ZnT8
7. A conformation-locking inhibitor of SLC15A4 with TASL proteostatic anti-inflammatory activity
8. Structural basis for recruitment of TASL by SLC15A4 in human endolysosomal TLR signaling
9. Experimental and Computational Analysis of Newly Identified Pathogenic Mutations in the Creatine Transporter SLC6A8
10. PCYT2-regulated lipid biosynthesis is critical to muscle health and ageing
11. LRP8‐mediated selenocysteine uptake is a targetable vulnerability in MYCN‐amplified neuroblastoma
12. A structure and evolutionary-based classification of solute carriers
13. Membrane transporters modulating the toxicity of arsenic, cadmium, and mercury in human cells.
14. Targeting solute carriers to modulate receptor–ligand interactions
15. Recent developments in ligands and chemical probes targeting solute carrier transporters
16. Author Correction: PCYT2-regulated lipid biosynthesis is critical to muscle health and ageing
17. Patient-derived model systems and the development of next-generation anticancer therapeutics
18. Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells
19. Cell-surface SLC nucleoside transporters and purine levels modulate BRD4-dependent chromatin states
20. EU-LIFE charter of independent life science research institutes
21. TASL is the SLC15A4-associated adaptor for IRF5 activation by TLR7–9
22. The promise and peril of chemical probes
23. Crystal structure of an SH2-kinase construct of c-Abl and effect of the SH2 domain on kinase activity.
24. Metabolic drug survey highlights cancer cell dependencies and vulnerabilities
25. Convergent use of phosphatidic acid for hepatitis C virus and SARS-CoV-2 replication organelle formation
26. Cross-species analysis of viral nucleic acid interacting proteins identifies TAOKs as innate immune regulators
27. Transcriptional Responses to IFN-γ Require Mediator Kinase-Dependent Pause Release and Mechanistically Distinct CDK8 and CDK19 Functions
28. Insights into the transport side of the human SLC38A9 transceptor
29. FOXO3 is involved in the tumor necrosis factor-driven inflammatory response in fibroblast-like synoviocytes
30. Identification and Characterization of Novel Small-Molecule Enhancers of the CUL3LZTR1E3 Ligase KRAS Complex
31. Experimental and Computational Analysis of Newly Identified Pathogenic Mutations in the Creatine Transporter SLC6A8
32. LZTR1 is a regulator of RAS ubiquitination and signaling
33. Recent advances in combinatorial drug screening and synergy scoring
34. mTOR Senses Environmental Cues to Shape the Fibroblast-like Synoviocyte Response to Inflammation
35. Polymerase [delta] deficiency causes syndromic immunodeficiency with replicative stress
36. The phosphatase UBASH3B/Sts-1 is a negative regulator of Bcr-Abl kinase activity and leukemogenesis
37. IRF1 is critical for the TNF-driven interferon response in rheumatoid fibroblast-like synoviocytes: JAKinibs suppress the interferon response in RA-FLSs
38. Systematic genetic mapping of necroptosis identifies SLC39A7 as modulator of death receptor trafficking
39. Combined chemosensitivity and chromatin profiling prioritizes drug combinations in CLL
40. Structure-Based Assembly of Protein Complexes in Yeast
41. The structure of the leukemia drug imatinib bound to human quinone reductase 2 (NQO2)
42. Discovery of Molecular Glue Degraders via Isogenic Morphological Profiling
43. Image-based ex-vivo drug screening for patients with aggressive haematological malignancies: interim results from a single-arm, open-label, pilot study
44. Epistasis-driven identification of SLC25A51 as a regulator of human mitochondrial NAD import
45. A substrate‐based ontology for human solute carriers
46. ProteoMutaMetrics: machine learning approaches for solute carrier family 6 mutation pathogenicity prediction.
47. EU‐LIFE charter of independent life science research institutes.
48. Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity
49. Absence of mitochondrial SLC25A51 enhances PARP1-dependent DNA repair by increasing nuclear NAD+ levels
50. Structural and functional annotation of solute carrier transporters: implication for drug discovery
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