1. A Small Pancreatic Neuroendocrine Tumor with Marked Pancreatic Duct Dilatation and Parenchymal Atrophy
- Author
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Y.J. Choi, Sangwoo Park, Hyoung Jung Kim, Seung-Mo Hong, Il-Young Jang, Sunghyun Won, and Myung-Hwan Kim
- Subjects
Pancreatic duct ,medicine.medical_specialty ,Stromal cell ,business.industry ,medicine.disease ,Malignancy ,Gastroenterology ,medicine.anatomical_structure ,Atrophy ,Fibrosis ,Internal medicine ,Parenchyma ,Immunohistochemistry ,Medicine ,business ,Pancreas - Abstract
Pancreatic ductal adenocarcinomas often cause marked pancreatic duct dilatation and associated parenchymal atrophy. We present the case of a small pancreatic neuroendocrine tumor with upstream pancreatic duct dilatation and severe parenchymal atrophy. A small enhancing tumor was observed at the head of the pancreas on computed tomography (CT). Endoscopic ultrasonographyguided fine-needle aspiration was negative for malignancy. We performed a pylorus-preserving pancreatoduodenectomy since we could not exclude the presence of pancreatic ductal adenocarcinoma. The pathological and immunohistochemical examination revealed a serotonin-positive neuroendocrine tumor, measured 1.0 × 0.5 cm. The pathological specimen was remarkable for the marked stromal fibrosis in the area of the tumor, which resulted in narrowing of the main pancreatic duct. Here, we report a rare small pancreatic neuroendocrine tumor, the CT image of which resembled that of pancreatic ductal adenocarcinoma, in which the expression of serotonin and associated fibrosis might be a possible mechanism for the marked main pancreatic duct dilatation. (Korean J Med 2014;86:598-602)
- Published
- 2014