Search

Your search keyword '"Sung, Rohyun"' showing total 32 results
Start Over Author "Sung, Rohyun"
32 results on '"Sung, Rohyun"'

6. Diagnostic Accuracy of the Initial Endoscopy for Ampullary Tumors

Author

Lee, Hee Seung, primary, Jang, Jong Soon, additional, Lee, Seungho, additional, Yeon, Myeong Ho, additional, Kim, Ki Bae, additional, Park, Jae Geun, additional, Lee, Joo Young, additional, Kim, Mi Jin, additional, Han, Joung-Ho, additional, Sung, Rohyun, additional, and Park, Seon Mee, additional

Published
2015
Full Text
View/download PDF

8. Differential Expression of E-Cadherin, β-Catenin, and S100A4 in Intestinal Type and Nonintestinal Type Ampulla of Vater Cancers

Author

Sung, Rohyun, primary, Kang, Li, additional, Han, Joung-Ho, additional, Choi, Jae-Woon, additional, Lee, Sang Hwa, additional, Lee, Tae Hoon, additional, Park, Sang-Heum, additional, Kim, Hong Ja, additional, Lee, Eaum Seok, additional, Kim, Young Suk, additional, Choi, Young Woo, additional, and Park, Seon Mee, additional

Published
2014
Full Text
View/download PDF

9. H2Receptor-Mediated Relaxation of Circular Smooth Muscle in Human Gastric Corpus: the Role of Nitric Oxide (NO)

Author

Lee, Sang Eok, primary, Kim, Dae Hoon, additional, Kim, Young Chul, additional, Han, Joung-Ho, additional, Choi, Woong, additional, Kim, Chan Hyung, additional, Jeong, Hye Won, additional, Park, Seon-Mee, additional, Yun, Sei Jin, additional, Choi, Song-Yi, additional, Sung, Rohyun, additional, Kim, Young Ho, additional, Yoo, Ra Young, additional, Sun, Park Hee, additional, Kim, Heon, additional, Song, Young-Jin, additional, Xu, Wen-Xie, additional, Yun, Hyo-Yung, additional, and Lee, Sang Jin, additional

Published
2014
Full Text
View/download PDF

11. Combined aberrant expression of E-cadherin and S100A4, but not β-catenin is associated with disease-free survival and overall survival in colorectal cancer patients

Author

Lee, Sang-Jeon, primary, Choi, Song Yi, additional, Kim, Wun-Jae, additional, Ji, Meiying, additional, Lee, Taek-Gu, additional, Son, Bo-Ra, additional, Yoon, Soon Man, additional, Sung, Rohyun, additional, Lee, Eun Jeoung, additional, Youn, Sei Jin, additional, and Park, Seon Mee, additional

Published
2013
Full Text
View/download PDF

13. Mechanism of Relaxation Via TASK-2 Channels in Uterine Circular Muscle of Mouse

Author

Hong, Seung Hwa, primary, Sung, Rohyun, additional, Kim, Young Chul, additional, Suzuki, Hikaru, additional, Choi, Woong, additional, Park, Yeon Jin, additional, Ji, Ill Woon, additional, Kim, Chan Hyung, additional, Myung, Sun Chul, additional, Lee, Moo Yeol, additional, Kang, Tong Mook, additional, You, Ra Young, additional, Lee, Kwang Ju, additional, Lim, Seung Woon, additional, Yun, Hyo-Yung, additional, Song, Young-Jin, additional, Xu, Wen-Xie, additional, Kim, Hak Soon, additional, and Lee, Sang Jin, additional

Published
2013
Full Text
View/download PDF

15. High K+-Induced Relaxation by Nitric Oxide in Human Gastric Fundus

Author

Kim, Dae Hoon, primary, Kim, Young Chul, additional, Choi, Woong, additional, Yun, Hyo-Young, additional, Sung, Rohyun, additional, Kim, Hun Sik, additional, Kim, Heon, additional, Yoo, Ra Young, additional, Park, Seon-Mee, additional, Yun, Sei Jin, additional, Song, Young-Jin, additional, Xu, Wen-Xie, additional, and Lee, Sang Jin, additional

Published
2012
Full Text
View/download PDF

19. Regional Distribution of Interstitial Cells of Cajal (ICC) in Human Stomach

Author

Yun, Hyo-Yung, primary, Sung, Rohyun, additional, Kim, Young Chul, additional, Choi, Woong, additional, Kim, Hun Sik, additional, Kim, Heon, additional, Lee, Gwang Ju, additional, You, Ra Young, additional, Park, Seon-Mee, additional, Yun, Sei Jin, additional, Kim, Mi-Jung, additional, Kim, Won Seop, additional, Song, Young-Jin, additional, Xu, Wen-Xie, additional, and Lee, Sang Jin, additional

Published
2010
Full Text
View/download PDF

21. Successful Hemostasis with Recombinant Activated Factor VII in a Patient with Massive Hepatic Subcapsular Hematoma

Author

Lee, Ju-Hee, primary, Chae, Hee Bok, additional, Seo, Eui-Keun, additional, Jeon, Won Joong, additional, Jeong, Hye Won, additional, Shin, Yoon Mi, additional, Bae, Jang Whan, additional, Kwon, Soon Kil, additional, Bae, Il Hun, additional, Shim, Woo Sub, additional, Shin, Dong Ick, additional, Sung, Rohyun, additional, and Kim, Ji Yoon, additional

Published
2009
Full Text
View/download PDF

25. A Case of Idiopathic Adulthood Ductopenia

Author

Park, Byeong Chool, primary, Park, Seon Mee, additional, Choi, Eun Young, additional, Chae, Hee Bok, additional, Yoon, Se Jin, additional, Sung, Rohyun, additional, and Lee, Sung Koo, additional

Published
2009
Full Text
View/download PDF

29. H2 Receptor-Mediated Relaxation of Circular Smooth Muscle in Human Gastric Corpus: the Role of Nitric Oxide (NO).

Author

Lee SE, Kim DH, Kim YC, Han JH, Choi W, Kim CH, Jeong HW, Park SM, Yun SJ, Choi SY, Sung R, Kim YH, Yoo RY, Sun PH, Kim H, Song YJ, Xu WX, Yun HY, and Lee SJ

Abstract

This study was designed to examine the effects of histamine on gastric motility and its specific receptor in the circular smooth muscle of the human gastric corpus. Histamine mainly produced tonic relaxation in a concentration-dependent and reversible manner, although histamine enhanced contractility in a minor portion of tissues tested. Histamine-induced tonic relaxation was nerve-insensitive because pretreatment with nerve blockers cocktail (NBC) did not inhibit relaxation. Additionally, K(+) channel blockers, such as tetraethylammonium (TEA), apamin (APA), and glibenclamide (Glib), had no effect. However, N(G)-nitro-L-arginine methyl ester (L-NAME) and 1H-(1,2,4)oxadiazolo (4,3-A) quinoxalin-1-one (ODQ), an inhibitor of soluble guanylate cyclase (sGC), did inhibit histamine-induced tonic relaxation. In particular, histamine-induced tonic relaxation was converted to tonic contraction by pretreatment with L-NAME. Ranitidine, the H2 receptor blocker, inhibited histamine-induced tonic relaxation. These findings suggest that histamine produced relaxation in circular smooth muscle of human gastric smooth muscle through H2 receptor and NO/sGC pathways.

Published
2014
Full Text
View/download PDF

30. Nitric Oxide-mediated Relaxation by High K in Human Gastric Longitudinal Smooth Muscle.

Author

Kim YC, Choi W, Yun HY, Sung R, Yoo RY, Park SM, Yun SJ, Kim MJ, Song YJ, Xu WX, and Lee SJ

Abstract

This study was designed to elucidate high-K(+)induced response of circular and longitudinal smooth muscle from human gastric corpus using isometric contraction. Contraction from circular and longitudinal muscle stripes of gastric corpus greater curvature and lesser curvature were compared. Circular smooth muscle from corpus greater curvature showed high K(+) (50 mM)-induced tonic contraction. On the contrary, however, longitudinal smooth muscle strips showed high K(+) (50 mM)-induced sustained relaxation. To find out the reason for the discrepancy we tested several relaxation mechanisms. Protein kinase blockers like KT5720, PKA inhibitor, and KT5823, PKG inhibitor, did not affect high K(+)-induced relaxation. K(+) channel blockers like tetraethylammonium (TEA), apamin (APA), glibenclamide (Glib) and barium (Ba(2+)) also had no effect. However, N(G)-nitro-L-arginine (L-NNA) and 1H-(1,2,4) oxadiazolo (4,3-A) quinoxalin-1-one (ODQ), an inhibitor of soluble guanylate cyclase (sGC) and 4-AP (4-aminopyridine), voltage-dependent K(+) channel (K(V)) blocker, inhibited high K(+)-induced relaxation, hence reversing to tonic contraction. High K(+)-induced relaxation was observed in gastric corpus of human stomach, but only in the longitudinal muscles from greater curvature not lesser curvature. L-NNA, ODQ and K(V) channel blocker sensitive high K(+)-induced relaxation in longitudinal muscle of higher portion of corpus was also observed. These results suggest that longitudinal smooth muscle from greater curvature of gastric corpus produced high K(+)-induced relaxation which was activated by NO/sGC pathway and by K(V) channel dependent mechanism.

Published
2011
Full Text
View/download PDF

31. Interstitial cells of Cajal (ICC)-like-c-Kit positive cells are involved in gastritis and carcinogenesis in human stomach.

Author

Sung R, Kim YC, Yun HY, Choi W, Kim HS, Kim H, Lee KJ, You RY, Park SM, Youn SJ, Kim MJ, Kim WS, Song YJ, Kim SY, Xu WX, and Lee SJ

Subjects
Adult, Aged, Gastric Fundus metabolism, Gastric Mucosa metabolism, Gastritis pathology, Humans, Inflammation, Male, Metaplasia, Middle Aged, Muscle, Smooth metabolism, Stomach Neoplasms pathology, Gastritis metabolism, Gene Expression Regulation, Neoplastic, Interstitial Cells of Cajal cytology, Proto-Oncogene Proteins c-kit metabolism, Stomach Neoplasms metabolism
Abstract

This study was executed to prove the existence of c-Kit-positive interstitial cells of Cajal (ICC)-like cells [c-Kit (+) ICC-like cells] and their possible role associated with gastric inflammation and/or carcinogenesis in human gastric mucosa. c-Kit (+) ICC-like cells were observed throughout all the layers of the gastric fundus along the greater curvature. Dense fusiform cell bodies with many processes were found in each layer. We also studied the c-Kit-positive immunoreactivity distribution pattern in the mucosa. c-Kit (+) cells were found mainly around the epithelial repair zone of the normal gastric fundus/corpus and of the fundus/corpus with non-metaplastic chronic gastritis. Notably, they were found attached to the epithelia of the repair zone in non-metaplastic chronic gastritis. In chronic gastritis with intestinal metaplasia, they were found scattered everywhere in the stroma of the gastric mucosa and did not attach to the metaplastic epithelium. We found c-Kit (+) ICC-like cells in human mucosa. They were present mainly in the stroma around the repair zone of the glands in chronic gastritis as well as in normal mucosa, whereas they seemed to redistribute over the whole mucosa in gastritis with intestinal metaplasia. These cells around the repair zone were found to be tightly attached to epithelial cells, but not to metaplastic epithelial cells. Thus, c-Kit (+) ICC-like cells appear to have a role in the epithelial recovery process and may be associated with carcinogenesis of human gastric mucosa.

Published
2011
Full Text
View/download PDF

32. [An experimental model of hepatic fibrosis induced by alcohol and CCl4: can the lipopolysaccharide prevent liver injury induced by alcohol and CCl4?].

Author

Chae HB, Jang LC, Park SM, Son BR, Sung R, and Choi JW

Subjects
Animals, Female, Liver pathology, Liver Cirrhosis, Alcoholic pathology, Rats, Rats, Sprague-Dawley, Carbon Tetrachloride Poisoning complications, Ethanol toxicity, Lipopolysaccharides administration & dosage, Liver Cirrhosis, Alcoholic prevention & control
Abstract

Background/aims: It is well known that alcohol enhances the toxicity of CCl4. We tried to establish an alcoholic liver cirrhosis model by administration of alcohol and CCl4 to rats. We also wanted to know the hepatoprotective effect of low doses of lipopolysaccharide(LPS) in this animal model., Methods: Of 20 female adult rats, 8 were ingested with alcohol ad libitum(group 1) Another 6 were ingested with 10% alcohol and 50% 1mL/kg CCl4 intragastrically by Sonde twice a week(group 2) The remaining 6 were ingested with 10% alcohol, CCl4, and 0.1mg/kg LPS intraperitoneally twice a week(group 3) The fibrosis was evaluated semiquantitatively on a scale of 0(none) to 3(cirrhosis)., Results: 1) After 10 weeks, septal fibrosis or cirrhosis was produced in 9 out of 12 rats in groups 2 and 3 but there was no fibrotic change in group 1. 2) There was no significant difference in pathological grading between groups 2 and 3., Conclusions: Hepatic fibrosis or cirrhosis can be sufficiently induced by alcohol and repetitive CCl4 ingestion for 10 weeks. We can not prove the hepatoprotective effect of low dose LPS by semiquantitative evaluation of pathological grading.

Published
2002

Catalog

Books, media, physical & digital resources
See catalog results