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7. Mapping medication selling practices at nonpharmacy outlets during the COVID-19 pandemic: an example of Indonesia.

Author

Wibowo, Yosi Irawati, Yana, I Gusti Agung Ari Kusuma, Sari, Gusti Ayu Putu Laksmi Puspa, Brata, Cecilia, Sunderland, Bruce, and Setiadi, Adji Prayitno

Abstract

Objectives: Nonpharmacy outlets are common medication suppliers in Indonesia, yet little is known regarding their practices. This study aimed to evaluate the medication selling practices occurring in kiosks and minimarkets during the coronavirus disease 2019 pandemic. Methods: A cross-sectional study included all minimarkets (N = 101) and a convenience sample of kiosks (a minimum sample size, N = 67) in District X, Indonesia. A validated tool was used to collect data on the characteristics of kiosks/minimarkets and their medication selling practices (i.e. drug management and drug information). Key findings: A sample of 67 kiosks and 52 minimarkets (response rate 51.5%) consented to participate in this study. Kiosks and minimarkets generally stocked nonprescription drugs, particularly cough and/or common cold products or analgesic-antipyretics; while >90% of kiosks and 15.4% of minimarkets provided prescription medicines. Medications in kiosks and minimarkets were mainly obtained from pharmacies (94.0% vs. 17.0%, respectively) or pharmaceutical wholesale representatives (68.7% vs. 96.0%, respectively). Most minimarkets or kiosks satisfied drug storage standards (100.0% vs. 88.1%, respectively). During the previous week, >80% of kiosks and minimarkets reported purchases of nonprescription drugs, and approximately 5% reported sales of prescription drugs. No drug information was provided by kiosk or minimarket staff. Conclusions: Minimarkets and kiosks may improve access to basic medications, but no information is provided regarding their use. These outlets should be licensed and policed to ensure the range and quality of drugs, and information provided to the Indonesian community is appropriate. [ABSTRACT FROM AUTHOR]

Published
2024
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11. Contributors

Author

Bonham, Maxine P., primary, Cai, Fang, additional, Chang, Jane Pei-Chen, additional, Chen, Daniel Tzu-Li, additional, Chen, Jocelyn Chia-Yu, additional, Chen, Zhen-Yu, additional, Clark, Katya M., additional, Deo, Permal, additional, Dhillon, Varinderpal, additional, Fenech, Michael, additional, Fu, Yuanqing, additional, Guo, Xiao-fei, additional, He, Canxia, additional, He, Wen-Sen, additional, Hettiarachchi, Dhanushka, additional, Hu, Xiang, additional, Hu, Xiaojie, additional, Huang, Jian-Ying, additional, Huang, Tao, additional, Huggins, Catherine E., additional, Hung, Ling-Shen, additional, James, Anthony P., additional, Jayasooriya, Anura P., additional, Jia, Min, additional, Lee, Sarah D., additional, Li, Duo, additional, Li, Jiaomei, additional, Li, Kelei, additional, Liu, Yandi, additional, Ma, Wen-Jun, additional, Premarathna, Amal D., additional, Qi, Ce, additional, Shi, Yan, additional, Sinclair, Andrew J., additional, Singh, Anish, additional, Su, Kuan-Pin, additional, Sun, Jin, additional, Sunderland, Bruce, additional, Tang, Jun, additional, Tian, Yunyi, additional, Wan, Yi, additional, Wang, Ling, additional, Wang, Xiang-Yang, additional, Xiu, Li-Li, additional, Xu, Tongcheng, additional, Yang, Bo, additional, Yu, Renqiang, additional, Yuan, Gaofeng, additional, Zhang, Xiaohong, additional, Zheng, Ju-Sheng, additional, Zhuang, Zhenhuang, additional, and Zou, Zuquan, additional

Published
2022
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13. The use of psychotropic medications in autistic individuals (21 years and younger) in Western Australia: A preliminary investigation.

Author

Bulonza, Roselyne, Watkins, Kim, Parsons, Richard, Sunderland, Bruce, Whitehouse, Andrew, Caccetta, Rima, Bulonza, Roselyne, Watkins, Kim, Parsons, Richard, Sunderland, Bruce, Whitehouse, Andrew, and Caccetta, Rima

Abstract

Prescriptions and use of medications to treat mental health conditions in young autistic populations are inconsistent worldwide. This makes it hard to compare findings from international studies to the Australian autistic population, where there are limited relevant studies. Apart from risperidone, there are no other medications specified for direct use in autistic persons. This study aims to gain initial broad understanding of the use of medications, commonly prescribed for mental health conditions, specifically by autistics under the age of 21 years. We analysed data that were previously collected as part of the Western Australian Autism Biological Registry between 2011 and 2015 which amounted to 239 surveys completed on young persons with diagnosed autism. The questionnaires included information on co-occurring conditions, current or previous use of medications and reasons for use of the medications. Only one-quarter of the participants in this study reported using at least one mental health-related medication in their lifetime. The most reported medications were stimulants, antidepressants and antiepileptics. The reasons for using medication included managing attention deficit hyperactivity disorder, challenging behaviours, seizures, sleep difficulties and symptoms of anxiety and depression. The number of individuals reporting medication use in this study was lower compared to other developed countries. Nevertheless, these medications should be monitored due to limited understanding of their use to manage co-occurring symptoms in young autistic persons. The findings highlight the importance of ongoing research to better understand mental health-related medications and inform best practice.

Published
2024

14. Assessment of patient perceptions of counselling on oral antineoplastic agents by a dedicated cancer services pharmacist in an outpatient cancer clinic.

Author

McNabb, Lorna, Metrot, Eva, Ferrington, Micaela, Sunderland, Bruce, Parsons, Richard, Copeland, Tandy-Sue, Corscadden, Siobhan, Tong, Selina, and Czarniak, Petra

Subjects
HYPOGLYCEMIC agents, PATIENTS' attitudes, ANTINEOPLASTIC agents, OUTPATIENT medical care, COUNSELING, PHARMACIST-patient relationships
Abstract

Background: Oral antineoplastic agents have caused a paradigm shift in cancer treatment, however, they produce many unique challenges. Although oral antineoplastics can have complex administration regimes, low adherence rates and high possibilities of drug-drug interactions, they are administered unsupervised at home. Cancer services pharmacists have the required skillsets to improve patient outcomes associated with oral antineoplastic treatment by increasing patient health literacy, improving concordance and optimising administration protocols. Aim: To evaluate patients' perceptions, experiences and overall satisfaction with dedicated clinical pharmacist consultations in patients treated with oral antineoplastic agents at a major public hospital. Method: In this retrospective cross-sectional study at a quaternary hospital in Western Australia, data were collected by a paper questionnaire (mailed in March 2022) to a random sample of 191 patients initiated on oral antineoplastic drugs between January 2021 and February 2022. Demographics, prescribed antineoplastic drug/s, cancer type data were collected including using 5-point Likert scale questions assess patients' overall satisfaction with the clinical pharmacist consultations. Results: The questionnaire response rate was 27.7% (52/188) (mean age 63.2 years; 57.5% female). Most patients (42/52; 80.8%) were satisfied with pharmacist consultations, trusted the pharmacist's advice (45/52; 86.5%), considered that the pharmacist improved their understanding of how to manage side effects (43/52; 82.7%) and they provided an important service in outpatient care (45/52; 86.5%). Conclusion: Overall, patients reported positive perceptions, experiences, and satisfaction with the cancer services pharmacist counselling services during their oral antineoplastic treatment. [ABSTRACT FROM AUTHOR]

Published
2024
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22. Abstracts from the 1st JoPPP Conference on Pharmaceutical Policy and Practice: Shah Alam, Malaysia. 28-29 August 2019

Author

Mehmood, Salman, Hasan, Syed Muhammad Farid, Razzakova, Chinara Maratovna, Ziganshina, Liliya Eugenevna, Ganbat, Azjargal, Sanjjav, Tsetsegmaa, Sunderland, Bruce, Dorj, Gantuya, Dorj, Gereltuya, Satibi, Satibi, Rokhman, M. Rifqi, Aditama, Hardika, Kartini, Ika, Ambarsari, Rini, Pramesti, Fajar, Loh, Peng Yeow, Chua, Siew Siang, Karuppannan, Mahmathi, Verma, Rohit Kumar, Paraidathathu, Thomas, Taha, Nur Akmar, Chong, Wei Wen, Rosli, M. Rozaini, Neoh, Chin Fen, Karuppannan, Mahmathi, Hassan, W. Nazariah W., Mahmud, Mahani, Rahimi, Afifah, Wu, David Bin-Chia, Teh, Ren Ee, Ali, Adliah Mhd, Mustapha, Mohammed, Zainal, Hadzliana, Tangiisuran, Balamurugan, Harun, Sabariah Noor, Looi, Irene, Sidek, Norsima Nazifah, Ibrahim, Khairul Azmi, Wei, Loo Keat, Yee, Lee Keng, Aziz, Zariah Abdul, Al-Sunaidar, Khalid A., Aziz, Noorizan Abd, Hassan, Yahaya, Hameed, Mohamed Abdul, Shaari, Nur Fatihah Binti, Karuppannan, Mahmathi, Ismail, Hasnah, Wong, Yuet Yen, Neoh, Chin Fen, Ramlan, Rifqa Danisha Nadhrah, Raman, Wan Asma Najiha A., Radzaini, Syazani Salman, Ghani, Norazila Abdul, Lean, Qi Ying, Neoh, Chin Fen, Wong, Yuet Yen, Md Shariff, A., Karuppannan, M., Gnanasan, S., Aziz N, A., Zaini, Muhammad Helmi, Wahab, Mohd Shahezwan Abd, Lkhagvasuren, Dulmaa, Dorjbal, Enkhjargal, Leghari, Qurratul-ain, Aslam, Muhammad Shahzad, Malick, Neelum, Kashif, Sadia, Bawani, Sharmeen, Ahmad, Nur Sufiza Bt, Hatah, Ernieda, Makmor-Bakry, Mohd, Nagaria, Raveena Amee, Hasan, Syed Shahzad, Babar, Zaheer Ud-Din, Faller, Erwin Martinez, Madelo, Jesa, Tolentino, Edward Agravante, Noordin, Zakiah Mohd, Karuppannan, Mahmathi, Fen, Neoh Chin, Ghazali, Nor Haizan Ibrahim, El-Dahiyat, F., Rashrash, M., Abuhamdah, S., Abu Farha, R., Khan, Amjad, Khan, Amer Hayat, Sulaiman, Syed Azhar Syed, Adnan, Azreen Syazril, Mushtaq, Saima, Fadzil, Maisarah Mohamad, Akmal, Muhammad Hadif Syahmi Mohd, Wong, Yuet Yen, Neoh, Chin Fen, Lean, Qi Ying, Malini, Christina, Wahab, Noor Azizah Binti Abdul, Shamsuddin, Ahmad Fuad, Dali, Ahmad Fauzi, Patah, Norfarahin Abd, Ibrahim, Noorizam, Cheah, Min H., Gan, Eon T., Azman, Nur J., Kori, Najma, Periyasamy, Petrick, Abdul-Aziz, Siti-Azdiah, Ismail, Wan Ismahanisa, Hassali, Mohamed Azmi Ahmad, Farooqui, Maryam, Roslan, Muhammad Nabil Fikri, Rahim, Nurhidayah Ab, Dzulkarnain, Syarifah Masyitah Habib, Chigome, Audrey K., Matlala, Moliehi, Meyer, Johanna C., Zaidi, Nur Hazirah Izzati, Saman, Kamaliah Md, Fahrni, Mathumalar Loganathan, Sani, Fajaratunur A., Gnanasan, Shubashini, Karuppannan, Mahmathi, Alhebs, Dema Nasser, Hussin, Nur Sabiha Md, Gnanasan, Shubashini, Karupannan, Mahmathi, Gopalan, Yogheswaran, Gankhulug, Badamkhand, Tegshee, Otgonbileg, Dorj, Gereltuya, Sanjjav, Tsetsegmaa, Sunderland, Bruce, Dorj, Gantuya, Ganbat, Azjargal, Dorj, Gereltuya, Sanjjav, Tsetsegmaa, Sunderland, Bruce, Dorj, Gantuya, Ariunaa, D., Purevsuren, S., Tugsbileg, S., Boditsetseg, B., Baigalmaa, D., Bolor, B., Otgonbat, B., Mandahnaran, P., Alhatlani, Asma, Alshehaitan, Nujud, Alherabi, Amjad, Farooqui, Maryam, Gill, M. S., Basari, A. H., Adnan, M. A., Mat Rahim, M. A., Fauzi, Nurul Atika Mohd, Hamidi, Nurin Hasya, Rahman, Muhammad Amin Azizul, Ghani, Norazila Abdul, Lean, Qi Ying, Neoh, Chin Fen, Wong, Yuet Yen, Nasrudin, Izzah Zahra, Zaki, Nur Izzati Mohd, Ismail, Muhammad Fareez Nazwaad, Ghani, Norazila Abdul, Lean, Qi Ying, Neoh, Chin Fen, Wong, Yuet Yen, Aslam, Adeel, Zin, Che Suraya, Syafinaz, Norny, Ahmad, Syed Imran, Jamshed, Shazia, Yahaya, H., Suriana, H. A., Izyan, A. W., Amlizan, R., Phodha, Tuangrat, Riewpaiboon, Arthorn, Malathum, Kumthorn, Coyte, Peter C., Othman, Nursyuhadah, Wong, Yuet Yen, Lean, Qi Ying, Noor, Nurain Mohd, Neoh, Chin Fen, Lertsinudom, Sunee, Niamtaworn, Pawalee, Tanpichart, Sirirat, Alkhalidi, Doaa, Jamshed, Shazia Qasim, Elkalmi, Ramadan Mohamed, Baig, Mirza Rafi, Aslam, Adeel, Hassali, Mohamed Azmi, Usir, Ezlina, Azman, Nurul Hafizah, Ismail, Hasnah, Fahrni, Mathumalar Loganathan, Rafar, Noor Razilah Abdul, Neoh, Chin Fen, Othman, Muhamad Faiz, Bahrin, Nur Zuhaida Zainal, Zaid, Wan Sazrina Wan, Zamri, Fauziah, Andayani, Nurita, Ariani, Farida, Sarnianto, Prih, Sofia, Zarith, Naimat, Faiza, Fahrni, Mathumalar Loganathan, Min, Beh Huai, Yaacob, Nor Liana Che, Ngadimon, Irma Wati, Fahrni, Mathumalar Loganathan, Rahman, Safwanah, Zunaidi, Nasrul Nazim Husna, Suhaimi, Azyyati Mohd, Manan, M. M., Jamaluddin, N. L., Manan, M. M., Nadiah Loke, A. L., Khan, Muhammad Anwar Nawab, Saroge, Nurin Alya Bt, Khan, Muhammad Anwar Nawab, Ng, Wang S., Wong, Pey C., and Said, Siti N. Md

Published
2020
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35. Specialist pharmacist consultations with cancer patients in a pharmacist‐led anticancer clinic.

Author

Soggee, Johnathan, Hunt, Maddaleine, O'Callaghan, Barbara, Lam, Wei‐Sen, Cannell, Paul, Boardman, Glenn, Sunderland, Bruce, and Czarniak, Petra

Subjects
CANCER patients, PHARMACISTS, PHARMACIST-patient relationships, ELECTRONIC health records, MEDICATION therapy management, DRUG carriers, NURSE practitioners
Abstract

Background: Prescription‐related errors and misinterpretation of oral cancer treatment instructions can lead to significant harm or fatal outcomes for patients. The impact of specialist pharmacist‐led consultation for patients taking oral antineoplastic medicines (OAMs) across a range of cancer types in an Australian setting has not been studied. Aim: To evaluate the impact of specialist cancer pharmacist patient consultation in a pharmacist‐led anticancer clinic across a range of cancer types and evaluate health service staff perceptions of these consultations. Method: Retrospective data were collected from electronic patient medical records from 2017 to 2020 at a Western Australian quaternary hospital. The impacts of pharmacist clinical interventions were classified using a validated tool and specialist interdisciplinary panel consensus. An online staff survey was conducted using Qualtrics. Results: Of 246 patients reviewed, 76 (30.8%, p <.001) had received a clinical intervention of which 48 (63.2%) were classified as high‐extreme and 28 (36.8%) as low‐moderate impact (p =.021). Patients on ≥5 concurrent medications or > 65 years may represent high risk groups. Thirty‐seven clinical staff were surveyed (37/55; 67.3%) and all strongly agreed/ agreed pharmacist consultation improved patient understanding and medication management confidence (p <.001). All cancer center staff (26/26) strongly agreed/agreed the clinic added value to the cancer service (p <.001), and 96.2% perceived it improved patient outcomes (p <.001). Conclusions: Specialist pharmacist‐led patient consultation for patients on OAM regimens may protect patients from high and extreme risk of harm. Specialist interdisciplinary staff supported this service. [ABSTRACT FROM AUTHOR]

Published
2023
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40. Loading of artesunate with MIL100(Fe) nanoparticles and evaluation of anti-cancer activity in a human breast cancer cell line

Author

Haydar, Murder Al, Gedawy, Ahmed, Abide, Hussein R., Zargar, Masoumeh, Brook, Naomi, Dass, Crispin, Sunderland, Bruce, Haydar, Murder Al, Gedawy, Ahmed, Abide, Hussein R., Zargar, Masoumeh, Brook, Naomi, Dass, Crispin, and Sunderland, Bruce

Abstract

Artesunate (ART), an anti-malarial drug, is nowadays used for the treatment of several types of cancers. It is sparingly soluble in water; therefore, it requires the development of a modified formulation of this drug to enhance its water solubility and stability. MIL100(Fe) nanoparticles, a metal-organic framework, were selected as the drug carrier. Purpose: This study aimed to employ MIL-100 (Fe) as a carrier for ART to investigate the release profile of ART and evaluate in vitro its anti-cancer activity. Methods: ART loading was achieved by mixing ART with MIL100(Fe) in the proportion of (1:1) and (1:2) to form ART-1MIL100(Fe) and ART-2MIL100(Fe), respectively. Only ART-2MIL100(Fe) was coated with 0.5% chitosan (CH) to form CH-ART-2MIL100(Fe). Free ART, ART-2MIL100(Fe), and CH-ART-2MIL100(Fe) were evaluated for anti-cancer activity in a human breast cancer cell line. Results: The ART loading capacity was 65% ± 1.3 and 75% ± 2.2 for ART-MIL100(Fe) and ART-2MIL100(Fe), respectively. The release profiles showed 50% ± 2.3 and 63% ± 1.5 of cumulative ART percent release for ART-2MIL100(Fe) and CH-ART-2MIL100(Fe), respectively. Although free ART demonstrated inhibition of cell viability (81%), ART-2MIL100(Fe) and CH-ART-2MIL100(Fe) showed cell inhibition viability of 56 and 51%, respectively. Conclusion: ART loading within MIL100(Fe) was effective and in vitro breast anti-cancer effect was significant.

Published
2022

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