816 results on '"Sunazuka, Toshiaki"'
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2. Virgaricins C and D, new pramanicin analogs produced by Apiospora sp. FKI-8058
3. The potentiation activity of β-lactam by phomoidrides and oxasetin against methicillin-resistant Staphylococcus aureus
4. Antifungal profile against Candida auris clinical isolates of tyroscherin and its new analog produced by the deep-sea-derived fungal strain Scedosporium apiospermum FKJ-0499
5. A novel aromatic compound from the fungus Synnemellisia sp. FKR-0921
6. A novel 12-membered ring non-antibiotic macrolide EM982 attenuates cytokine production by inhibiting IKKβ and IκBα phosphorylation
7. Variational autoencoder-based chemical latent space for large molecular structures with 3D complexity
8. A combination strategy of a semisynthetic macrolide, 5-O-mycaminosyltylonolide with polymyxin B nonapeptide for multi-drug resistance P. aeruginosa
9. New antimalarial fusarochromanone analogs produced by the fungal strain Fusarium sp. FKI-9521
10. A novel macrolide–Del-1 axis to regenerate bone in old age
11. An efflux pump deletion mutant enabling the discovery of a macrolide as an overlooked anti-P. aeruginosa active compound
12. A new selective inhibitor for IMP-1 metallo-β-lactamase, 3Z,5E-octa-3,5-diene-1,3,4-tricarboxylic acid-3,4-anhydride
13. Pot-economical synthesis of cyclic depsipeptides using a hydrophobic anchor molecule toward the construction of an unnatural peptide library
14. Afidopyropen, a novel insecticide originating from microbial secondary extracts
15. Sesquicillin F, a new insecticidal meroterpenoid produced by Mariannaea macrochlamydospora FKI-4735
16. Efficient Total Synthesis of Ōmura Natural Products
17. Trichothioneic acid, a new antioxidant compound produced by the fungal strain Trichoderma virens FKI-7573
18. Nanaomycin K, a new epithelial–mesenchymal transition inhibitor produced by the actinomycete “Streptomyces rosa subsp. notoensis” OS-3966
19. The non-antibiotic macrolide EM900 attenuates HDM and poly(I:C)-induced airway inflammation with inhibition of macrophages in a mouse model
20. Jietacins, azoxy natural products, as novel NF-κB inhibitors: Discovery, synthesis, biological activity, and mode of action
21. Nanaomycin I and J: New nanaomycins generated by mycothiol-mediated compounds from “Streptomyces rosa subsp. notoensis” OS-3966
22. 特異な構造を有する大村天然物の新規分子骨格構築法開発と実践的全合成
23. Jietacins, azoxy antibiotics with potent nematocidal activity: Design, synthesis, and biological evaluation against parasitic nematodes
24. Azithromycin, a 15-membered macrolide antibiotic, inhibits influenza A(H1N1)pdm09 virus infection by interfering with virus internalization process
25. Synthesis and insecticidal efficacy of pyripyropene derivatives. Part II—Invention of afidopyropen
26. Fusaramin, an antimitochondrial compound produced by Fusarium sp., discovered using multidrug-sensitive Saccharomyces cerevisiae
27. Stereostructure of Luminamicin, an Anaerobic Antibiotic, via Molecular Dynamics, NMR Spectroscopy, and the Modified Mosher Method
28. Deep generative model of constructing chemical latent space for large molecular structures with 3D complexity
29. Deep generative model of constructing chemical latent space for small to large molecular structures with 3D complexity
30. Studies on the Catechin Constituents of Bark of Cinnamomum sieboldii
31. Suppression of Bone Resorption by Madindoline A, a Novel Nonpeptide Antagonist to gp130
32. A Potent PDK4 Inhibitor for Treatment of Heart Failure with Reduced Ejection Fraction.
33. Synthesis and insecticidal efficacy of pyripyropene derivatives focusing on the C-1, C-7, and C-11 positions’ substituent groups
34. Narrow-spectrum inhibitors targeting an alternative menaquinone biosynthetic pathway of Helicobacter pylori
35. Development of a nitrogen-bound hydrophobic auxiliary: application to solid/hydrophobic-tag relay synthesis of calpinactam
36. Hakuhybotrol, a polyketide produced by Hypomyces pseudocorticiicola, characterized with the assistance of 3D ED/MicroED
37. An architectonic macrolide library based on a C2-symmetric macrodiolide toward pharmaceutical compositions
38. Jietacins with potent nematocidal activity; efficient isolation of novel analogs and divergent total synthesis of jietacin A, B, C, and D
39. Jietacin Derivative Inhibits TNF-α-Mediated Inflammatory Cytokines Production via Suppression of the NF-κB Pathway in Synovial Cells
40. Chemical Degradation-Inspired Total Synthesis of the Antibiotic Macrodiolide, Luminamicin
41. Ivermectin Inhibits HBV Entry into the Nucleus by Suppressing KPNA2
42. 5-O-Mycaminosyltylonolide antibacterial derivatives: design, synthesis and bioactivity
43. Total synthesis of (±)-naphthacemycin A9, possessing both antibacterial activity against methicillin-resistant Staphylococcus aureus and circumventing effect of β-lactam resistance
44. Naphthacemycins, novel circumventors of β-lactam resistance in MRSA, produced by Streptomyces sp. KB-3346-5. II. Structure elucidation
45. Ivermectin efficacy against Biomphalaria, intermediate host snail vectors of Schistosomiasis
46. Identification of pyripyropene A as a promising insecticidal compound in a microbial metabolite screening
47. Macrolides Promote CCL2-Mediated Macrophage Recruitment and Clearance of Nasopharyngeal Pneumococcal Colonization in Mice
48. Koshidacins A and B, Antiplasmodial Cyclic Tetrapeptides from the Okinawan Fungus Pochonia boninensis FKR-0564
49. An Anthelmintic Compound, Nafuredin, Shows Selective Inhibition of Complex I in Helminth Mitochondria
50. Synthesis and stereochemical determination of an antiparasitic pseudo-aminal type monoterpene indole alkaloid
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