Search

Introduction: Minimal invasive surgery techniques are getting more popular by surgeons relying their advantages such as pain control, feasibility and increased affinity. Both techniques have similar prognostic influence regarding survival in colon cancer but increased versatility of laparoscopy in years shows more tendency of laparoscopy among surgeons. This study aims to evaluate of surgical site infection (SSI) rates between conventional and laparoscopic colon cancer procedures. Materials and Methods: Patients operated due to colon adenocarcinoma between 2018 and 2023 evaluated. Emergency, palliative or incomplete resections excluded. Demographic, pathologic, peroperative and postoperative records of patients evaluated. Patients seperated into groups by SSI occurance and surgical method choice. Results: SSI development was found higher in conventional surgery group (30.0% vs 11.6%; p=0.013). In comparison of patients by SSI development; only intraoperative Red Blood Concentrate (RBC) replacement founded to be higher in SSI (+) group (0±1 vs 0±1; p=0.002). All variables associated with SSI development were subjected to univariate regression analysis. It's shown that only conventional surgery choice was a indipendant risk factor for SSI development (OR: 3.489 (1.289 - 9.415); p=0.017). Conclusion: Laparoscopic colon surgery has better SSI rates than conventional colon surgery procedures. Our findings are similar with the general view on SSI ratio's between two surgical practices. [ABSTRACT FROM AUTHOR]

Introduction: The laparoscopic approach is preferred in colorectal cancer cases, yet concerns arise regarding the development of complications among the elderly patient population. This study aims to investigate the difference in the development of major complications between patients aged 65 and older undergoing laparoscopic procedures for colorectal cancer diagnoses and the younger patients. Materials and Methods: Between 2013 and 2023, records of patients who underwent laparoscopic surgery due to colorectal cancers at our center were extracted. Demographic characteristics, pathology data, complications developed during hospitalization, and lengths of stay were gathered from hospital records. Results: A total of 72 patients were included in the study, with 18 patients aged 65 and older and 54 patients aged younger than 65. When patients were evaluated based on the development of major and minor complications, all demographic and pathological characteristics were found to be similar. Only in the group of patients aged 65 and older, the length of hospital stay was found to be longer (p<0.001). In the multivariate analysis conducted, age was not found to be significant for the development of major complications (OR: 0.895 [0.246-3.264], p=0.897). Conclusion: This study has shown that being aged 65 or older or younger is not associated with the development of major complications in patients undergoing surgery for colorectal cancer. It has also demonstrated that laparoscopic surgical procedures can be safely used in patients aged 65 and older. Further studies with larger patient cohorts could provide more clarity on this topic. [ABSTRACT FROM AUTHOR]

Objectives: Colorectal cancer remains a significant health concern, necessitating reliable prognostic indicators for effective management. This study explores the preoperative prognostic significance of the Glucose/Lymphocyte Ratio (GLR) in colorectal cancers. Methods: The study retrospectively analyzed records of patients who underwent surgery for elective colorectal cancers between January 1, 2013, and December 31, 2021, at the Koşuyolu Training and Research Hospital Gastroenterologic Surgery Department. Demographic, clinicopathological, and follow-up data were comprehensively assessed. A cutoff was established from GLR ratios and patients were divided into two groups for prognosis analysis. Results: The study enrolled 222 eligible patients, examining variables such as age, sex, ASA score, neoadjuvant treatment, lymphovascular and perineural invasion, tumor grade, TNM stage, and GLR. The groups consisted of 128 patients with low GLR and 94 patients with high GLR. Statistical analyses revealed relations between GLR levels (p ≤ 0.001) and various prognostic factors such as age (p = 0.034), Perineural Invasion (PNI) (p = 0.002), tumor grade (p = 0.017), TNM stage (p = 0.003), and surgery time (p = 0.029), individuals with GLR ≥ 3.04 were observed to show higher mortality rates (p = 0.001). Above GLR cutoff point of 3.04 patients showed better overall survival rates. All survival related parameters were related with prognosis in univariant Cox regression tests. In multivariant cox regression tests GLR ≥ 3.04 significantly increased mortality by 2.9 times. (p = 0.003). Conclusion: This study demonstrates that GLR, calculated from preoperative glucose and lymphocyte values serves as an independent prognostic factor in colorectal cancers. The findings suggest potential applications for GLR in survival analyses, with significant associations identified in age, PNI, tumor grade, TNM stage, and surgery time. Further investigations are warranted in homogeneous patient populations. [ABSTRACT FROM AUTHOR]